-
1
-
-
84872338388
-
Therapy for fibrotic diseases: Nearing the starting line
-
sr1
-
Friedman SL, Sheppard D, Duffield JS, Violette S (2013) Therapy for fibrotic diseases: Nearing the starting line. Sci Transl Med 5(167):167sr1.
-
(2013)
Sci Transl Med
, vol.5
, Issue.167
, pp. 167
-
-
Friedman, S.L.1
Sheppard, D.2
Duffield, J.S.3
Violette, S.4
-
2
-
-
67650480995
-
Transforming growth factor beta as a therapeutic target in systemic sclerosis
-
Varga J, Pasche B (2009) Transforming growth factor beta as a therapeutic target in systemic sclerosis. Nat Rev Rheumatol 5(4):200-206.
-
(2009)
Nat Rev Rheumatol
, vol.5
, Issue.4
, pp. 200-206
-
-
Varga, J.1
Pasche, B.2
-
3
-
-
2942592429
-
Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40
-
Sugamura K, Ishii N, Weinberg AD (2004) Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40. Nat Rev Immunol 4(6):420-431.
-
(2004)
Nat Rev Immunol
, vol.4
, Issue.6
, pp. 420-431
-
-
Sugamura, K.1
Ishii, N.2
Weinberg, A.D.3
-
4
-
-
77955965216
-
OX40-OX40 ligand interaction in T-cellmediated immunity and immunopathology
-
Ishii N, Takahashi T, Soroosh P, Sugamura K (2010) OX40-OX40 ligand interaction in T-cellmediated immunity and immunopathology. Adv Immunol 105:63-98.
-
(2010)
Adv Immunol
, vol.105
, pp. 63-98
-
-
Ishii, N.1
Takahashi, T.2
Soroosh, P.3
Sugamura, K.4
-
5
-
-
84937894061
-
OX40, OX40L and autoimmunity: A comprehensive review
-
Webb GJ, Hirschfield GM, Lane PJL (2016) OX40, OX40L and autoimmunity: A comprehensive review. Clin Rev Allergy Immunol 50(3):312-332.
-
(2016)
Clin Rev Allergy Immunol
, vol.50
, Issue.3
, pp. 312-332
-
-
Webb, G.J.1
Hirschfield, G.M.2
Lane, P.J.L.3
-
6
-
-
77949451240
-
Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis
-
Gourh P, et al. (2010) Association of TNFSF4 (OX40L) polymorphisms with susceptibility to systemic sclerosis. Ann Rheum Dis 69(3):550-555.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.3
, pp. 550-555
-
-
Gourh, P.1
-
7
-
-
79952359835
-
A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort
-
Bossini-Castillo L, et al. (2011) A replication study confirms the association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis in a large European cohort. Ann Rheum Dis 70(4):638-641.
-
(2011)
Ann Rheum Dis
, vol.70
, Issue.4
, pp. 638-641
-
-
Bossini-Castillo, L.1
-
8
-
-
84860741366
-
Independent replication and meta analysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis
-
Coustet B, et al. (2012) Independent replication and meta analysis of association studies establish TNFSF4 as a susceptibility gene preferentially associated with the subset of anticentromere-positive patients with systemic sclerosis. J Rheumatol 39(5):997-1003.
-
(2012)
J Rheumatol
, vol.39
, Issue.5
, pp. 997-1003
-
-
Coustet, B.1
-
9
-
-
57349168552
-
Increased serum soluble OX40 in patients with systemic sclerosis
-
Komura K, et al. (2008) Increased serum soluble OX40 in patients with systemic sclerosis. J Rheumatol 35(12):2359-2362.
-
(2008)
J Rheumatol
, vol.35
, Issue.12
, pp. 2359-2362
-
-
Komura, K.1
-
10
-
-
84893836044
-
OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis
-
Gwyer Findlay E, et al. (2014) OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis. Proc Natl Acad Sci USA 111(6):2289-2294.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.6
, pp. 2289-2294
-
-
Gwyer Findlay, E.1
-
11
-
-
84860464142
-
Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis
-
Avouac J, et al. (2012) Inhibition of activator protein 1 signaling abrogates transforming growth factor β-mediated activation of fibroblasts and prevents experimental fibrosis. Arthritis Rheum 64(5):1642-1652.
-
(2012)
Arthritis Rheum
, vol.64
, Issue.5
, pp. 1642-1652
-
-
Avouac, J.1
-
12
-
-
77957668307
-
Animal models of systemic sclerosis: Prospects and limitations
-
Beyer C, Schett G, Distler O, Distler JHW (2010) Animal models of systemic sclerosis: Prospects and limitations. Arthritis Rheum 62(10):2831-2844.
-
(2010)
Arthritis Rheum
, vol.62
, Issue.10
, pp. 2831-2844
-
-
Beyer, C.1
Schett, G.2
Distler, O.3
Distler, J.H.W.4
-
13
-
-
0017250167
-
Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton
-
Green MC, Sweet HO, Bunker LE (1976) Tight-skin, a new mutation of the mouse causing excessive growth of connective tissue and skeleton. Am J Pathol 82(3):493-512.
-
(1976)
Am J Pathol
, vol.82
, Issue.3
, pp. 493-512
-
-
Green, M.C.1
Sweet, H.O.2
Bunker, L.E.3
-
14
-
-
77957286169
-
Causes and risk factors for death in systemic sclerosis: A study from the EULAR Scleroderma Trials and Research (EUSTAR) database
-
Tyndall AJ, et al. (2010) Causes and risk factors for death in systemic sclerosis: A study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Ann Rheum Dis 69(10):1809-1815.
-
(2010)
Ann Rheum Dis
, vol.69
, Issue.10
, pp. 1809-1815
-
-
Tyndall, A.J.1
-
15
-
-
84863812038
-
Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis
-
Maurer B, et al. (2012) Fra-2 transgenic mice as a novel model of pulmonary hypertension associated with systemic sclerosis. Ann Rheum Dis 71(8):1382-1387.
-
(2012)
Ann Rheum Dis
, vol.71
, Issue.8
, pp. 1382-1387
-
-
Maurer, B.1
-
16
-
-
73449115656
-
Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis
-
Maurer B, et al. (2009) Transcription factor fos-related antigen-2 induces progressive peripheral vasculopathy in mice closely resembling human systemic sclerosis. Circulation 120(23):2367-2376.
-
(2009)
Circulation
, vol.120
, Issue.23
, pp. 2367-2376
-
-
Maurer, B.1
-
17
-
-
34548739767
-
Mechanisms of scleroderma-induced lung disease
-
du Bois RM (2007) Mechanisms of scleroderma-induced lung disease. Proc Am Thorac Soc 4(5):434-438.
-
(2007)
Proc Am Thorac Soc
, vol.4
, Issue.5
, pp. 434-438
-
-
Du Bois, R.M.1
-
18
-
-
84883771144
-
Treatment of early diffuse systemic sclerosis skin disease
-
Frech TM, et al. (2013) Treatment of early diffuse systemic sclerosis skin disease. Clin Exp Rheumatol 31(2, Suppl 76):166-171.
-
(2013)
Clin Exp Rheumatol
, vol.31
, Issue.2
, pp. 166-171
-
-
Frech, T.M.1
-
19
-
-
0032955192
-
Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: Amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein
-
Higgins LM, et al. (1999) Regulation of T cell activation in vitro and in vivo by targeting the OX40-OX40 ligand interaction: Amelioration of ongoing inflammatory bowel disease with an OX40-IgG fusion protein, but not with an OX40 ligand-IgG fusion protein. J Immunol 162(1):486-493.
-
(1999)
J Immunol
, vol.162
, Issue.1
, pp. 486-493
-
-
Higgins, L.M.1
-
20
-
-
0035451519
-
Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis
-
Ndhlovu LC, Ishii N, Murata K, Sato T, Sugamura K (2001) Critical involvement of OX40 ligand signals in the T cell priming events during experimental autoimmune encephalomyelitis. J Immunol 167(5):2991-2999.
-
(2001)
J Immunol
, vol.167
, Issue.5
, pp. 2991-2999
-
-
Ndhlovu, L.C.1
Ishii, N.2
Murata, K.3
Sato, T.4
Sugamura, K.5
-
21
-
-
0345303882
-
CD134 plays a crucial role in the pathogenesis of EAE and is upregulated in the CNS of patients with multiple sclerosis
-
Carboni S, et al. (2003) CD134 plays a crucial role in the pathogenesis of EAE and is upregulated in the CNS of patients with multiple sclerosis. J Neuroimmunol 145(1-2):1-11.
-
(2003)
J Neuroimmunol
, vol.145
, Issue.1-2
, pp. 1-11
-
-
Carboni, S.1
-
22
-
-
65349112520
-
The significance of OX40 and OX40L to T-cell biology and immune disease
-
Croft M, So T, Duan W, Soroosh P (2009) The significance of OX40 and OX40L to T-cell biology and immune disease. Immunol Rev 229(1):173-191.
-
(2009)
Immunol Rev
, vol.229
, Issue.1
, pp. 173-191
-
-
Croft, M.1
So, T.2
Duan, W.3
Soroosh, P.4
-
23
-
-
0031572569
-
Expression and function of OX40 ligand on human dendritic cells
-
Ohshima Y, et al. (1997) Expression and function of OX40 ligand on human dendritic cells. J Immunol 159(8):3838-3848.
-
(1997)
J Immunol
, vol.159
, Issue.8
, pp. 3838-3848
-
-
Ohshima, Y.1
-
24
-
-
47249116959
-
Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival
-
Song J, So T, Croft M (2008) Activation of NF-kappaB1 by OX40 contributes to antigen-driven T cell expansion and survival. J Immunol 180(11):7240-7248.
-
(2008)
J Immunol
, vol.180
, Issue.11
, pp. 7240-7248
-
-
Song, J.1
So, T.2
Croft, M.3
-
25
-
-
0033568008
-
Intracellular signaling of gp34, the OX40 ligand: Induction of c-jun and c-fos mRNA expression through gp34 upon binding of its receptor, OX40
-
Matsumura Y, Hori T, Kawamata S, Imura A, Uchiyama T (1999) Intracellular signaling of gp34, the OX40 ligand: Induction of c-jun and c-fos mRNA expression through gp34 upon binding of its receptor, OX40. J Immunol 163(6):3007-3011.
-
(1999)
J Immunol
, vol.163
, Issue.6
, pp. 3007-3011
-
-
Matsumura, Y.1
Hori, T.2
Kawamata, S.3
Imura, A.4
Uchiyama, T.5
-
26
-
-
0037108529
-
Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases
-
Murata K, et al. (2002) Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases. J Immunol 169(8):4628-4636.
-
(2002)
J Immunol
, vol.169
, Issue.8
, pp. 4628-4636
-
-
Murata, K.1
-
27
-
-
84923882858
-
Cellular interactions in the pathogenesis of interstitial lung diseases
-
Bagnato G, Harari S (2015) Cellular interactions in the pathogenesis of interstitial lung diseases. Eur Respir Rev 24(135):102-114.
-
(2015)
Eur Respir Rev
, vol.24
, Issue.135
, pp. 102-114
-
-
Bagnato, G.1
Harari, S.2
-
28
-
-
83455195470
-
Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension
-
Rabieyousefi M, et al. (2011) Indispensable roles of OX40L-derived signal and epistatic genetic effect in immune-mediated pathogenesis of spontaneous pulmonary hypertension. BMC Immunol 12:67.
-
(2011)
BMC Immunol
, vol.12
, pp. 67
-
-
Rabieyousefi, M.1
-
29
-
-
84890816552
-
OX40L blockade and allergen-induced airway responses in subjects with mild asthma. Clin Exp
-
Gauvreau GM, et al. (2014) OX40L blockade and allergen-induced airway responses in subjects with mild asthma. Clin Exp Allergy 44(1):29-37.
-
(2014)
Allergy
, vol.44
, Issue.1
, pp. 29-37
-
-
Gauvreau, G.M.1
-
30
-
-
0142218995
-
A critical role for OX40 in T cell-mediated immunopathology during lung viral infection
-
Humphreys IR, et al. (2003) A critical role for OX40 in T cell-mediated immunopathology during lung viral infection. J Exp Med 198(8):1237-1242.
-
(2003)
J Exp Med
, vol.198
, Issue.8
, pp. 1237-1242
-
-
Humphreys, I.R.1
-
31
-
-
84938152992
-
Predictive value of serial high-resolution computed tomography analyses and concurrent lung function tests in systemic sclerosis
-
Hoffmann-Vold A-M, et al. (2015) Predictive value of serial high-resolution computed tomography analyses and concurrent lung function tests in systemic sclerosis. Arthritis Rheumatol 67(8):2205-2212.
-
(2015)
Arthritis Rheumatol
, vol.67
, Issue.8
, pp. 2205-2212
-
-
Hoffmann-Vold, A.-M.1
-
32
-
-
75649110070
-
Animal model of systemic sclerosis
-
Yamamoto T (2010) Animal model of systemic sclerosis. J Dermatol 37(1):26-41.
-
(2010)
J Dermatol
, vol.37
, Issue.1
, pp. 26-41
-
-
Yamamoto, T.1
-
33
-
-
84877596388
-
Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis
-
Avouac J, et al. (2013) Critical role of the adhesion receptor DNAX accessory molecule-1 (DNAM-1) in the development of inflammation-driven dermal fibrosis in a mouse model of systemic sclerosis. Ann Rheum Dis 72(6):1089-1098.
-
(2013)
Ann Rheum Dis
, vol.72
, Issue.6
, pp. 1089-1098
-
-
Avouac, J.1
-
34
-
-
84861824342
-
Sunitinib inhibits the phosphorylation of platelet-derived growth factor receptor β in the skin of mice with scleroderma-like features and prevents the development of the disease
-
Kavian N, et al. (2012) Sunitinib inhibits the phosphorylation of platelet-derived growth factor receptor β in the skin of mice with scleroderma-like features and prevents the development of the disease. Arthritis Rheum 64(6):1990-2000.
-
(2012)
Arthritis Rheum
, vol.64
, Issue.6
, pp. 1990-2000
-
-
Kavian, N.1
-
35
-
-
79953676584
-
Inactivation of the transcription factor STAT-4 prevents inflammationdriven fibrosis in animal models of systemic sclerosis
-
Avouac J, et al. (2011) Inactivation of the transcription factor STAT-4 prevents inflammationdriven fibrosis in animal models of systemic sclerosis. Arthritis Rheum 63(3):800-809.
-
(2011)
Arthritis Rheum
, vol.63
, Issue.3
, pp. 800-809
-
-
Avouac, J.1
-
36
-
-
0018252844
-
Comparison of gold levels and distribution in Guinea pig serum
-
Kamel H, et al. (1978) Comparison of gold levels and distribution in guinea pig serum. Arthritis Rheum 21(4):441-446.
-
(1978)
Arthritis Rheum
, vol.21
, Issue.4
, pp. 441-446
-
-
Kamel, H.1
-
37
-
-
0023914820
-
Simple method of estimating severity of pulmonary fibrosis on a numerical scale
-
Ashcroft T, Simpson JM, Timbrell V (1988) Simple method of estimating severity of pulmonary fibrosis on a numerical scale. J Clin Pathol 41(4):467-470.
-
(1988)
J Clin Pathol
, vol.41
, Issue.4
, pp. 467-470
-
-
Ashcroft, T.1
Simpson, J.M.2
Timbrell, V.3
-
38
-
-
77249151384
-
Fibrillar collagen scoring by second harmonic microscopy: A new tool in the assessment of liver fibrosis
-
Gailhouste L, et al. (2010) Fibrillar collagen scoring by second harmonic microscopy: A new tool in the assessment of liver fibrosis. J Hepatol 52(3):398-406.
-
(2010)
J Hepatol
, vol.52
, Issue.3
, pp. 398-406
-
-
Gailhouste, L.1
-
39
-
-
0018887574
-
Preliminary criteria for the classification of systemic sclerosis (scleroderma)
-
Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee (1980) Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 23(5):581-590.
-
(1980)
Arthritis Rheum
, vol.23
, Issue.5
, pp. 581-590
-
-
-
40
-
-
0023854176
-
Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis
-
LeRoy EC, et al. (1988) Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis. J Rheumatol 15(2):202-205.
-
(1988)
J Rheumatol
, vol.15
, Issue.2
, pp. 202-205
-
-
LeRoy, E.C.1
-
41
-
-
67649657743
-
The 4th world symposium on pulmonary hypertension
-
Humbert M, McLaughlin VV (2009) The 4th world symposium on pulmonary hypertension. J Am Coll Cardiol 54(1 Suppl):S1-117.
-
(2009)
J Am Coll Cardiol
, vol.54
, Issue.1
, pp. S1-S117
-
-
Humbert, M.1
McLaughlin, V.V.2
-
42
-
-
0027729083
-
Skin thickness score in systemic sclerosis: An assessment of interobserver variability in 3 independent studies
-
Clements PJ, et al. (1993) Skin thickness score in systemic sclerosis: An assessment of interobserver variability in 3 independent studies. J Rheumatol 20(11):1892-1896.
-
(1993)
J Rheumatol
, vol.20
, Issue.11
, pp. 1892-1896
-
-
Clements, P.J.1
-
43
-
-
84920400485
-
Performance of the 2013 American college of Rheumatology/European league against rheumatism classification criteria for systemic sclerosis (SSc) in large, well-defined cohorts of SSc and mixed connective tissue disease
-
Hoffmann-Vold A-M, Gunnarsson R, Garen T, Midtvedt Ø, Molberg Ø (2015) Performance of the 2013 American College of Rheumatology/European League Against Rheumatism Classification Criteria for Systemic Sclerosis (SSc) in large, well-defined cohorts of SSc and mixed connective tissue disease. J Rheumatol 42(1):60-63.
-
(2015)
J Rheumatol
, vol.42
, Issue.1
, pp. 60-63
-
-
Hoffmann-Vold, A.-M.1
Gunnarsson, R.2
Garen, T.3
Midtvedt, Ø.4
Molberg, Ø.5
-
44
-
-
44449152061
-
Interstitial lung disease in systemic sclerosis: A simple staging system
-
Goh NSL, et al. (2008) Interstitial lung disease in systemic sclerosis: A simple staging system. Am J Respir Crit Care Med 177(11):1248-1254.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, Issue.11
, pp. 1248-1254
-
-
Goh, N.S.L.1
|