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Infection and Immunity
Volumn 84, Issue 7, 2016, Pages 2031-2041
RpiRc is a pleiotropic effector of virulence determinant synthesis and attenuates pathogenicity in Staphylococcus aureus
Author keywords

[No Author keywords available]
Indexed keywords

ACNA PROTEIN; BACTERIAL PROTEIN; BACTERIAL RNA; MGRA PROTEIN; RNAIII; RPIRC PROTEIN; SIGB PROTEIN; SMAD ANCHOR FOR RECEPTOR ACTIVATION; UNCLASSIFIED DRUG; REPRESSOR PROTEIN; VIRULENCE FACTOR;
EID: 84976866394     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00285-16     Document Type: Article
Times cited : (26)
References (90)
  • 1
    • 0032551901 scopus 로고    scopus 로고
    • Staphylococcus aureus infections
    • Lowy FD. 1998. Staphylococcus aureus infections. N Engl J Med 339:520-532. http://dx.doi.org/10.1056/NEJM199808203390806.
    • (1998) N Engl J Med , vol.339 , pp. 520-532
    • Lowy, F.D.1
  • 2
    • 66749141589 scopus 로고    scopus 로고
    • At the crossroads of bacterial metabolism and virulence factor synthesis in staphylococci
    • Somerville GA, Proctor RA. 2009. At the crossroads of bacterial metabolism and virulence factor synthesis in staphylococci. Microbiol Mol Biol Rev 73:233-248. http://dx.doi.org/10.1128/MMBR.00005-09.
    • (2009) Microbiol Mol Biol Rev , vol.73 , pp. 233-248
    • Somerville, G.A.1    Proctor, R.A.2
  • 3
    • 80655142472 scopus 로고    scopus 로고
    • RpiR homologues may link Staphylococcus aureus RNAIII synthesis and pentose phosphate pathway regulation
    • Zhu Y, Nandakumar R, Sadykov MR, Madayiputhiya N, Luong TT, Gaupp R, Lee CY, Somerville GA. 2011. RpiR homologues may link Staphylococcus aureus RNAIII synthesis and pentose phosphate pathway regulation. J Bacteriol 193:6187-6196. http://dx.doi.org/10.1128/JB .05930-11.
    • (2011) J Bacteriol , vol.193 , pp. 6187-6196
    • Zhu, Y.1    Nandakumar, R.2    Sadykov, M.R.3    Madayiputhiya, N.4    Luong, T.T.5    Gaupp, R.6    Lee, C.Y.7    Somerville, G.A.8
  • 4
    • 58549096736 scopus 로고    scopus 로고
    • Quorum sensing in staphylococci
    • Novick RP, Geisinger E. 2008. Quorum sensing in staphylococci. Annu Rev Genet 42:541-564. http://dx.doi.org/10.1146/annurev.genet.42.110807.091640.
    • (2008) Annu Rev Genet , vol.42 , pp. 541-564
    • Novick, R.P.1    Geisinger, E.2
  • 5
    • 0029785913 scopus 로고    scopus 로고
    • The molecular architecture of the sar locus in Staphylococcus aureus
    • Bayer MG, Heinrichs JH, Cheung AL. 1996. The molecular architecture of the sar locus in Staphylococcus aureus. J Bacteriol 178:4563-4570.
    • (1996) J Bacteriol , vol.178 , pp. 4563-4570
    • Bayer, M.G.1    Heinrichs, J.H.2    Cheung, A.L.3
  • 6
    • 84870243803 scopus 로고    scopus 로고
    • The staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates themRNAturnover properties of late-exponential and stationary-phase Staphylococcus aureus cells
    • Morrison JM, Anderson KL, Beenken KE, Smeltzer MS, Dunman PM. 2012. The staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates themRNAturnover properties of late-exponential and stationary-phase Staphylococcus aureus cells. Front Cell Infect Microbiol 2:26. http://dx.doi.org/10.3389/fcimb.2012.00026.
    • (2012) Front Cell Infect Microbiol , vol.2 , pp. 26
    • Morrison, J.M.1    Anderson, K.L.2    Beenken, K.E.3    Smeltzer, M.S.4    Dunman, P.M.5
  • 7
    • 0033035830 scopus 로고    scopus 로고
    • The staphylococcal accessory regulator (sar) represses transcription of the Staphylococcus aureus collagen adhesin gene (cna) in an agr-independent manner
    • Blevins JS, Gillaspy AF, Rechtin TM, Hurlburt BK, Smeltzer MS. 1999. The staphylococcal accessory regulator (sar) represses transcription of the Staphylococcus aureus collagen adhesin gene (cna) in an agr-independent manner. Mol Microbiol 33:317-326. http://dx.doi.org/10.1046/j.1365-2958.1999.01475.x.
    • (1999) Mol Microbiol , vol.33 , pp. 317-326
    • Blevins, J.S.1    Gillaspy, A.F.2    Rechtin, T.M.3    Hurlburt, B.K.4    Smeltzer, M.S.5
  • 9
    • 0034036997 scopus 로고    scopus 로고
    • agr-independent regulation of fibronectinbinding protein(s) by the regulatory locus sar in Staphylococcus aureus
    • Wolz C, Pöhlmann-Dietze P, Steinhuber A, Chien YT, Manna A, van Wamel W, Cheung A. 2000. agr-independent regulation of fibronectinbinding protein(s) by the regulatory locus sar in Staphylococcus aureus. Mol Microbiol 36:230-243. http://dx.doi.org/10.1046/j.1365-2958.2000.01853.x.
    • (2000) Mol Microbiol , vol.36 , pp. 230-243
    • Wolz, C.1    Pöhlmann-Dietze, P.2    Steinhuber, A.3    Chien, Y.T.4    Manna, A.5    van Wamel, W.6    Cheung, A.7
  • 10
    • 80055050797 scopus 로고    scopus 로고
    • Coordinated regulation by AgrA, SarA, and SarR to control agr expression in Staphylococcus aureus
    • Reyes D, Andrey DO, Monod A, Kelley WL, Zhang G, Cheung AL. 2011. Coordinated regulation by AgrA, SarA, and SarR to control agr expression in Staphylococcus aureus. J Bacteriol 193:6020-6031. http://dx .doi.org/10.1128/JB.05436-11.
    • (2011) J Bacteriol , vol.193 , pp. 6020-6031
    • Reyes, D.1    Andrey, D.O.2    Monod, A.3    Kelley, W.L.4    Zhang, G.5    Cheung, A.L.6
  • 11
    • 0033601339 scopus 로고    scopus 로고
    • SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation
    • Chien Y, Manna AC, Projan SJ, Cheung AL. 1999. SarA, a global regulator of virulence determinants in Staphylococcus aureus, binds to a conserved motif essential for sar-dependent gene regulation. J Biol Chem 274:37169-37176. http://dx.doi.org/10.1074/jbc.274.52.37169.
    • (1999) J Biol Chem , vol.274 , pp. 37169-37176
    • Chien, Y.1    Manna, A.C.2    Projan, S.J.3    Cheung, A.L.4
  • 12
    • 0033871121 scopus 로고    scopus 로고
    • Analysis of genetic elements controlling Staphylococcus aureus lrgAB expression: potential role of DNA topology in SarA regulation
    • Fujimoto DF, Brunskill EW, Bayles KW. 2000. Analysis of genetic elements controlling Staphylococcus aureus lrgAB expression: potential role of DNA topology in SarA regulation. J Bacteriol 182:4822-4828. http://dx .doi.org/10.1128/JB.182.17.4822-4828.2000.
    • (2000) J Bacteriol , vol.182 , pp. 4822-4828
    • Fujimoto, D.F.1    Brunskill, E.W.2    Bayles, K.W.3
  • 13
    • 33144478753 scopus 로고    scopus 로고
    • Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus
    • Liu Y, Manna AC, Pan CH, Kriksunov IA, Thiel DJ, Cheung AL, Zhang G. 2006. Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus. Proc Natl Acad Sci U S A 103:2392-2397. http://dx.doi.org/10.1073/pnas.0510439103.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2392-2397
    • Liu, Y.1    Manna, A.C.2    Pan, C.H.3    Kriksunov, I.A.4    Thiel, D.J.5    Cheung, A.L.6    Zhang, G.7
  • 15
  • 16
    • 0027169704 scopus 로고
    • The accessory gene regulator (agr) controls Staphylococcus aureus virulence in a murine arthritis model
    • Abdelnour A, Arvidson S, Bremell T, Ryden C, Tarkowski A. 1993. The accessory gene regulator (agr) controls Staphylococcus aureus virulence in a murine arthritis model. Infect Immun 61:3879-3885.
    • (1993) Infect Immun , vol.61 , pp. 3879-3885
    • Abdelnour, A.1    Arvidson, S.2    Bremell, T.3    Ryden, C.4    Tarkowski, A.5
  • 17
    • 0028173022 scopus 로고
    • Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis
    • Cheung AL, Eberhardt KJ, Chung E, Yeaman MR, Sullam PM, Ramos M, Bayer AS. 1994. Diminished virulence of a sar-/agr- mutant of Staphylococcus aureus in the rabbit model of endocarditis. J Clin Invest 94:1815-1822. http://dx.doi.org/10.1172/JCI117530.
    • (1994) J Clin Invest , vol.94 , pp. 1815-1822
    • Cheung, A.L.1    Eberhardt, K.J.2    Chung, E.3    Yeaman, M.R.4    Sullam, P.M.5    Ramos, M.6    Bayer, A.S.7
  • 19
    • 0036385645 scopus 로고    scopus 로고
    • Regulation of Staphylococcus aureus type 5 capsular polysaccharides by agr and sarA in vitro and in an experimental endocarditis model
    • van Wamel W, Xiong YQ, Bayer AS, Yeaman MR, Nast CC, Cheung AL. 2002. Regulation of Staphylococcus aureus type 5 capsular polysaccharides by agr and sarA in vitro and in an experimental endocarditis model. Microb Pathog 33:73-79. http://dx.doi.org/10.1006/mpat.2002.0513.
    • (2002) Microb Pathog , vol.33 , pp. 73-79
    • van Wamel, W.1    Xiong, Y.Q.2    Bayer, A.S.3    Yeaman, M.R.4    Nast, C.C.5    Cheung, A.L.6
  • 21
    • 0028269858 scopus 로고
    • Role of the sar locus of Staphylococcus aureus in induction of endocarditis in rabbits
    • Cheung AL, Yeaman MR, Sullam PM, Witt MD, Bayer AS. 1994. Role of the sar locus of Staphylococcus aureus in induction of endocarditis in rabbits. Infect Immun 62:1719-1725.
    • (1994) Infect Immun , vol.62 , pp. 1719-1725
    • Cheung, A.L.1    Yeaman, M.R.2    Sullam, P.M.3    Witt, M.D.4    Bayer, A.S.5
  • 22
    • 0029909324 scopus 로고    scopus 로고
    • Role of the staphylococcal accessory gene regulator (sar) in septic arthritis
    • Nilsson IM, Bremell T, Ryden C, Cheung AL, Tarkowski A. 1996. Role of the staphylococcal accessory gene regulator (sar) in septic arthritis. Infect Immun 64:4438-4443.
    • (1996) Infect Immun , vol.64 , pp. 4438-4443
    • Nilsson, I.M.1    Bremell, T.2    Ryden, C.3    Cheung, A.L.4    Tarkowski, A.5
  • 23
    • 33644755944 scopus 로고    scopus 로고
    • Transcription profiling of the mgrA regulon in Staphylococcus aureus
    • Luong TT, Dunman PM, Murphy E, Projan SJ, Lee CY. 2006. Transcription profiling of the mgrA regulon in Staphylococcus aureus. J Bacteriol 188:1899-1910. http://dx.doi.org/10.1128/JB.188.5.1899-1910.2006.
    • (2006) J Bacteriol , vol.188 , pp. 1899-1910
    • Luong, T.T.1    Dunman, P.M.2    Murphy, E.3    Projan, S.J.4    Lee, C.Y.5
  • 24
    • 0037898948 scopus 로고    scopus 로고
    • Characterization of RAT, an autolysis regulator in Staphylococcus aureus
    • Ingavale SS, Van Wamel W, Cheung AL. 2003. Characterization of RAT, an autolysis regulator in Staphylococcus aureus. Mol Microbiol 48:1451-1466. http://dx.doi.org/10.1046/j.1365-2958.2003.03503.x.
    • (2003) Mol Microbiol , vol.48 , pp. 1451-1466
    • Ingavale, S.S.1    Van Wamel, W.2    Cheung, A.L.3
  • 25
    • 0038643232 scopus 로고    scopus 로고
    • Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus
    • Truong-Bolduc QC, Zhang X, Hooper DC. 2003. Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus. J Bacteriol 185:3127-3138. http://dx.doi.org/10.1128/JB .185.10.3127-3138.2003.
    • (2003) J Bacteriol , vol.185 , pp. 3127-3138
    • Truong-Bolduc, Q.C.1    Zhang, X.2    Hooper, D.C.3
  • 26
    • 0038715856 scopus 로고    scopus 로고
    • Mgr, a novel global regulator in Staphylococcus aureus
    • Luong TT, Newell SW, Lee CY. 2003. Mgr, a novel global regulator in Staphylococcus aureus. J Bacteriol 185:3703-3710. http://dx.doi.org/10.1128/JB.185.13.3703-3710.2003.
    • (2003) J Bacteriol , vol.185 , pp. 3703-3710
    • Luong, T.T.1    Newell, S.W.2    Lee, C.Y.3
  • 27
    • 33750230997 scopus 로고    scopus 로고
    • An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus
    • Chen PR, Bae T, Williams WA, Duguid EM, Rice PA, Schneewind O, He C. 2006. An oxidation-sensing mechanism is used by the global regulator MgrA in Staphylococcus aureus. Nat Chem Biol 2:591-595. http://dx .doi.org/10.1038/nchembio820.
    • (2006) Nat Chem Biol , vol.2 , pp. 591-595
    • Chen, P.R.1    Bae, T.2    Williams, W.A.3    Duguid, E.M.4    Rice, P.A.5    Schneewind, O.6    He, C.7
  • 28
    • 54849416961 scopus 로고    scopus 로고
    • mgrA regulates staphylococcal virulence important for induction and progression of septic arthritis and sepsis
    • Jonsson IM, Lindholm C, Luong TT, Lee CY, Tarkowski A. 2008. mgrA regulates staphylococcal virulence important for induction and progression of septic arthritis and sepsis. Microbes Infect 10:1229-1235. http://dx .doi.org/10.1016/j.micinf.2008.07.026.
    • (2008) Microbes Infect , vol.10 , pp. 1229-1235
    • Jonsson, I.M.1    Lindholm, C.2    Luong, T.T.3    Lee, C.Y.4    Tarkowski, A.5
  • 29
    • 15544372331 scopus 로고    scopus 로고
    • Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus
    • Ingavale S, van Wamel W, Luong TT, Lee CY, Cheung AL. 2005. Rat/MgrA, a regulator of autolysis, is a regulator of virulence genes in Staphylococcus aureus. Infect Immun 73:1423-1431. http://dx.doi.org/10.1128/IAI.73.3.1423-1431.2005.
    • (2005) Infect Immun , vol.73 , pp. 1423-1431
    • Ingavale, S.1    van Wamel, W.2    Luong, T.T.3    Lee, C.Y.4    Cheung, A.L.5
  • 30
    • 55549098541 scopus 로고    scopus 로고
    • Posttranslational modification influences the effects of MgrA on norA expression in Staphylococcus aureus
    • Truong-Bolduc QC, Ding Y, Hooper DC. 2008. Posttranslational modification influences the effects of MgrA on norA expression in Staphylococcus aureus. J Bacteriol 190:7375-7381. http://dx.doi.org/10.1128/JB.01068-08.
    • (2008) J Bacteriol , vol.190 , pp. 7375-7381
    • Truong-Bolduc, Q.C.1    Ding, Y.2    Hooper, D.C.3
  • 31
    • 0345829221 scopus 로고    scopus 로고
    • Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus
    • Cheung AL, Bayer AS, Zhang G, Gresham H, Xiong Y-Q. 2004. Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus. FEMS Immunol Med Microbiol 40:1-9. http://dx.doi.org/10.1016 /S0928-8244(03)00309-2.
    • (2004) FEMS Immunol Med Microbiol , vol.40 , pp. 1-9
    • Cheung, A.L.1    Bayer, A.S.2    Zhang, G.3    Gresham, H.4    Xiong, Y.-Q.5
  • 32
    • 80052396610 scopus 로고    scopus 로고
    • Vancomycin activates σB in vancomycin-resistant Staphylococcus aureus resulting in the enhancement of cytotoxicity
    • Chen HY, Chen CC, Fang CS, Hsieh YT, Lin MH, Shu JC. 2011. Vancomycin activates σB in vancomycin-resistant Staphylococcus aureus resulting in the enhancement of cytotoxicity. PLoS One 6:e24472. http: //dx.doi.org/10.1371/journal.pone.0024472.
    • (2011) PLoS One , vol.6
    • Chen, H.Y.1    Chen, C.C.2    Fang, C.S.3    Hsieh, Y.T.4    Lin, M.H.5    Shu, J.C.6
  • 33
    • 67349215276 scopus 로고    scopus 로고
    • Physiological proteomics and stress/starvation responses in Bacillus subtilis and Staphylococcus aureus
    • Hecker M, Reder A, Fuchs S, Pagels M, Engelmann S. 2009. Physiological proteomics and stress/starvation responses in Bacillus subtilis and Staphylococcus aureus. Res Microbiol 160:245-258. http://dx.doi.org/10.1016/j.resmic.2009.03.008.
    • (2009) Res Microbiol , vol.160 , pp. 245-258
    • Hecker, M.1    Reder, A.2    Fuchs, S.3    Pagels, M.4    Engelmann, S.5
  • 34
    • 0031659829 scopus 로고    scopus 로고
    • Deletion of the alternative sigma factor σB inStaphylococcus aureus reveals its function as a global regulator of virulence genes
    • Kullik I, Giachino P, Fuchs T. 1998. Deletion of the alternative sigma factor σB inStaphylococcus aureus reveals its function as a global regulator of virulence genes. J Bacteriol 180:4814-4820.
    • (1998) J Bacteriol , vol.180 , pp. 4814-4820
    • Kullik, I.1    Giachino, P.2    Fuchs, T.3
  • 35
    • 0030892308 scopus 로고    scopus 로고
    • The alternative sigma factor σB in Staphylococcus aureus: regulation of the sigB operon in response to growth phase and heat shock
    • Kullik II, Giachino P. 1997. The alternative sigma factor σB in Staphylococcus aureus: regulation of the sigB operon in response to growth phase and heat shock. Arch Microbiol 167:151-159. http://dx.doi.org/10.1007 /s002030050428.
    • (1997) Arch Microbiol , vol.167 , pp. 151-159
    • Kullik, I.I.1    Giachino, P.2
  • 37
    • 0034885090 scopus 로고    scopus 로고
    • Influence of a functional sigB operon on the global regulators sar and agr in Staphylococcus aureus
    • Bischoff M, Entenza JM, Giachino P. 2001. Influence of a functional sigB operon on the global regulators sar and agr in Staphylococcus aureus. J Bacteriol 183:5171-5179. http://dx.doi.org/10.1128/JB.183.17.5171-5179.2001.
    • (2001) J Bacteriol , vol.183 , pp. 5171-5179
    • Bischoff, M.1    Entenza, J.M.2    Giachino, P.3
  • 38
    • 0033012331 scopus 로고    scopus 로고
    • Hyperproduction of alphahemolysin in a sigB mutant is associated with elevated SarA expression in Staphylococcus aureus
    • Cheung AL, Chien YT, Bayer AS. 1999. Hyperproduction of alphahemolysin in a sigB mutant is associated with elevated SarA expression in Staphylococcus aureus. Infect Immun 67:1331-1337.
    • (1999) Infect Immun , vol.67 , pp. 1331-1337
    • Cheung, A.L.1    Chien, Y.T.2    Bayer, A.S.3
  • 39
    • 0030809034 scopus 로고    scopus 로고
    • Alternative transcription factor σSB of Staphylococcus aureus: characterization and role in transcription of the global regulatory locus sar
    • Deora R, Tseng T, Misra TK. 1997. Alternative transcription factor σSB of Staphylococcus aureus: characterization and role in transcription of the global regulatory locus sar. J Bacteriol 179:6355-6359.
    • (1997) J Bacteriol , vol.179 , pp. 6355-6359
    • Deora, R.1    Tseng, T.2    Misra, T.K.3
  • 40
    • 0036771636 scopus 로고    scopus 로고
    • sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4
    • Horsburgh MJ, Aish JL, White IJ, Shaw L, Lithgow JK, Foster SJ. 2002. sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J Bacteriol 184:5457-5467. http://dx.doi.org/10.1128/JB .184.19.5457-5467.2002.
    • (2002) J Bacteriol , vol.184 , pp. 5457-5467
    • Horsburgh, M.J.1    Aish, J.L.2    White, I.J.3    Shaw, L.4    Lithgow, J.K.5    Foster, S.J.6
  • 41
    • 0031829309 scopus 로고    scopus 로고
    • Transcriptional analysis of different promoters in the sar locus in Staphylococcus aureus
    • Manna AC, Bayer MG, Cheung AL. 1998. Transcriptional analysis of different promoters in the sar locus in Staphylococcus aureus. J Bacteriol 180:3828-3836.
    • (1998) J Bacteriol , vol.180 , pp. 3828-3836
    • Manna, A.C.1    Bayer, M.G.2    Cheung, A.L.3
  • 42
    • 34147112687 scopus 로고    scopus 로고
    • Enhanced post-stationary-phase survival of a clinical thymidinedependent small-colony variant of Staphylococcus aureus results from lack of a functional tricarboxylic acid cycle
    • Chatterjee I, Herrmann M, Proctor RA, Peters G, Kahl BC. 2007. Enhanced post-stationary-phase survival of a clinical thymidinedependent small-colony variant of Staphylococcus aureus results from lack of a functional tricarboxylic acid cycle. J Bacteriol 189:2936-2940. http: //dx.doi.org/10.1128/JB.01444-06.
    • (2007) J Bacteriol , vol.189 , pp. 2936-2940
    • Chatterjee, I.1    Herrmann, M.2    Proctor, R.A.3    Peters, G.4    Kahl, B.C.5
  • 43
    • 77951059306 scopus 로고    scopus 로고
    • Advantage of upregulation of succinate dehydrogenase in Staphylococcus aureus biofilms
    • Gaupp R, Schlag S, Liebeke M, Lalk M, Gotz F. 2010. Advantage of upregulation of succinate dehydrogenase in Staphylococcus aureus biofilms. J Bacteriol 192:2385-2394. http://dx.doi.org/10.1128/JB.01472-09.
    • (2010) J Bacteriol , vol.192 , pp. 2385-2394
    • Gaupp, R.1    Schlag, S.2    Liebeke, M.3    Lalk, M.4    Gotz, F.5
  • 44
    • 0036840950 scopus 로고    scopus 로고
    • Staphylococcus aureus aconitase inactivation unexpectedly inhibits post-exponential-phase growth and enhances stationary- phase survival
    • Somerville GA, Chaussee MS, Morgan CI, Fitzgerald JR, Dorward DW, Reitzer LJ, Musser JM. 2002. Staphylococcus aureus aconitase inactivation unexpectedly inhibits post-exponential-phase growth and enhances stationary- phase survival. Infect Immun 70:6373-6382. http://dx.doi.org/10.1128/IAI.70.11.6373-6382.2002.
    • (2002) Infect Immun , vol.70 , pp. 6373-6382
    • Somerville, G.A.1    Chaussee, M.S.2    Morgan, C.I.3    Fitzgerald, J.R.4    Dorward, D.W.5    Reitzer, L.J.6    Musser, J.M.7
  • 45
    • 0242575010 scopus 로고    scopus 로고
    • Synthesis and deformylation of Staphylococcus aureus delta-toxin are linked to tricarboxylic acid cycle activity
    • Somerville GA, Cockayne A, Dürr M, Peschel A, Otto M, Musser JM. 2003. Synthesis and deformylation of Staphylococcus aureus delta-toxin are linked to tricarboxylic acid cycle activity. J Bacteriol 185:6686-6694. http://dx.doi.org/10.1128/JB.185.22.6686-6694.2003.
    • (2003) J Bacteriol , vol.185 , pp. 6686-6694
    • Somerville, G.A.1    Cockayne, A.2    Dürr, M.3    Peschel, A.4    Otto, M.5    Musser, J.M.6
  • 46
    • 70349435418 scopus 로고    scopus 로고
    • Tricarboxylic acid cycle-dependent attenuation of Staphylococcus aureus in vivo virulence by selective inhibition of amino acid transport
    • Zhu Y, Xiong YQ, Sadykov MR, Fey PD, Lei MG, Lee CY, Bayer AS, Somerville GA. 2009. Tricarboxylic acid cycle-dependent attenuation of Staphylococcus aureus in vivo virulence by selective inhibition of amino acid transport. Infect Immun 77:4256-4264. http://dx.doi.org/10.1128 /IAI.00195-09.
    • (2009) Infect Immun , vol.77 , pp. 4256-4264
    • Zhu, Y.1    Xiong, Y.Q.2    Sadykov, M.R.3    Fey, P.D.4    Lei, M.G.5    Lee, C.Y.6    Bayer, A.S.7    Somerville, G.A.8
  • 47
    • 77955283399 scopus 로고    scopus 로고
    • CcpA mediates proline auxotrophy and is required for Staphylococcus aureus pathogenesis
    • Li C, Sun F, Cho H, Yelavarthi V, Sohn C, He C, Schneewind O, Bae T. 2010. CcpA mediates proline auxotrophy and is required for Staphylococcus aureus pathogenesis. J Bacteriol 192:3883-3892. http://dx.doi.org/10.1128/JB.00237-10.
    • (2010) J Bacteriol , vol.192 , pp. 3883-3892
    • Li, C.1    Sun, F.2    Cho, H.3    Yelavarthi, V.4    Sohn, C.5    He, C.6    Schneewind, O.7    Bae, T.8
  • 50
    • 65549131633 scopus 로고    scopus 로고
    • CodY in Staphylococcus aureus: a regulatory link between metabolism and virulence gene expression
    • Pohl K, Francois P, Stenz L, Schlink F, Geiger T, Herbert S, Goerke C, Schrenzel J, Wolz C. 2009. CodY in Staphylococcus aureus: a regulatory link between metabolism and virulence gene expression. J Bacteriol 191: 2953-2963. http://dx.doi.org/10.1128/JB.01492-08.
    • (2009) J Bacteriol , vol.191 , pp. 2953-2963
    • Pohl, K.1    Francois, P.2    Stenz, L.3    Schlink, F.4    Geiger, T.5    Herbert, S.6    Goerke, C.7    Schrenzel, J.8    Wolz, C.9
  • 54
    • 0028917215 scopus 로고
    • Protein kinase-dependent HPr/CcpA interaction links glycolytic activity to carbon catabolite repression in gram-positive bacteria
    • Deutscher J, Kuster E, Bergstedt U, Charrier V, Hillen W. 1995. Protein kinase-dependent HPr/CcpA interaction links glycolytic activity to carbon catabolite repression in gram-positive bacteria. Mol Microbiol 15: 1049-1053. http://dx.doi.org/10.1111/j.1365-2958.1995.tb02280.x.
    • (1995) Mol Microbiol , vol.15 , pp. 1049-1053
    • Deutscher, J.1    Kuster, E.2    Bergstedt, U.3    Charrier, V.4    Hillen, W.5
  • 56
    • 0033963304 scopus 로고    scopus 로고
    • Direct quantitative transcript analysis of the agr regulon of Staphylococcus aureus during human infection in comparison to the expression profile in vitro
    • Goerke C, Campana S, Bayer MG, Döring G, Botzenhart K, Wolz C. 2000. Direct quantitative transcript analysis of the agr regulon of Staphylococcus aureus during human infection in comparison to the expression profile in vitro. Infect Immun 68:1304-1311. http://dx.doi.org/10.1128 /IAI.68.3.1304-1311.2000.
    • (2000) Infect Immun , vol.68 , pp. 1304-1311
    • Goerke, C.1    Campana, S.2    Bayer, M.G.3    Döring, G.4    Botzenhart, K.5    Wolz, C.6
  • 57
    • 78751532081 scopus 로고    scopus 로고
    • Staphylococcus aureus ClpC divergently regulates capsule via sae and codY in strain Newman but activates capsule via codY in strain UAMS-1 and in strain Newman with repaired saeS
    • Luong TT, Sau K, Roux C, Sau S, Dunman PM, Lee CY. 2011. Staphylococcus aureus ClpC divergently regulates capsule via sae and codY in strain Newman but activates capsule via codY in strain UAMS-1 and in strain Newman with repaired saeS. J Bacteriol 193:686-694. http://dx.doi .org/10.1128/JB.00987-10.
    • (2011) J Bacteriol , vol.193 , pp. 686-694
    • Luong, T.T.1    Sau, K.2    Roux, C.3    Sau, S.4    Dunman, P.M.5    Lee, C.Y.6
  • 59
    • 33846814907 scopus 로고    scopus 로고
    • Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia
    • Bubeck Wardenburg J, Patel RJ, Schneewind O. 2007. Surface proteins and exotoxins are required for the pathogenesis of Staphylococcus aureus pneumonia. Infect Immun 75:1040-1044. http://dx.doi.org/10.1128/IAI
    • (2007) Infect Immun , vol.75 , pp. 1040-1044
    • Bubeck Wardenburg, J.1    Patel, R.J.2    Schneewind, O.3
  • 61
    • 33845388892 scopus 로고    scopus 로고
    • SarA is a repressor of hla (alpha-hemolysin) transcription in Staphylococcus aureus: its apparent role as an activator of hla in the prototype strain NCTC 8325 depends on reduced expression of sarS
    • Oscarsson J, Kanth A, Tegmark-Wisell K, Arvidson S. 2006. SarA is a repressor of hla (alpha-hemolysin) transcription in Staphylococcus aureus: its apparent role as an activator of hla in the prototype strain NCTC 8325 depends on reduced expression of sarS. J Bacteriol 188:8526-8533. http: //dx.doi.org/10.1128/JB.00866-06.
    • (2006) J Bacteriol , vol.188 , pp. 8526-8533
    • Oscarsson, J.1    Kanth, A.2    Tegmark-Wisell, K.3    Arvidson, S.4
  • 62
    • 77749279738 scopus 로고    scopus 로고
    • Tricarboxylic acid cycle-dependent synthesis of Staphylococcus aureus type 5 and 8 capsular polysaccharides
    • Sadykov MR, Mattes TA, Luong TT, Zhu Y, Day SR, Sifri CD, Lee CY, Somerville GA. 2010. Tricarboxylic acid cycle-dependent synthesis of Staphylococcus aureus type 5 and 8 capsular polysaccharides. J Bacteriol 192:1459-1462. http://dx.doi.org/10.1128/JB.01377-09.
    • (2010) J Bacteriol , vol.192 , pp. 1459-1462
    • Sadykov, M.R.1    Mattes, T.A.2    Luong, T.T.3    Zhu, Y.4    Day, S.R.5    Sifri, C.D.6    Lee, C.Y.7    Somerville, G.A.8
  • 63
    • 0032932006 scopus 로고    scopus 로고
    • The SIS domain: a phosphosugar-binding domain
    • Bateman A. 1999. The SIS domain: a phosphosugar-binding domain. Trends Biochem Sci 24:94-95. http://dx.doi.org/10.1016/S0968-0004(99)01357-2.
    • (1999) Trends Biochem Sci , vol.24 , pp. 94-95
    • Bateman, A.1
  • 64
    • 0030060223 scopus 로고    scopus 로고
    • Ribose catabolism of Escherichia coli: characterization of the rpiB gene encoding ribose phosphate isomerase B and of the rpiR gene, which is involved in regulation of rpiB expression
    • Sorensen KI, Hove-Jensen B. 1996. Ribose catabolism of Escherichia coli: characterization of the rpiB gene encoding ribose phosphate isomerase B and of the rpiR gene, which is involved in regulation of rpiB expression. J Bacteriol 178:1003-1011.
    • (1996) J Bacteriol , vol.178 , pp. 1003-1011
    • Sorensen, K.I.1    Hove-Jensen, B.2
  • 65
    • 0041744003 scopus 로고    scopus 로고
    • Correlation of acetate catabolism and growth yield in Staphylococcus aureus: implications for host-pathogen interactions
    • Somerville GA, Said-Salim B, Wickman JM, Raffel SJ, Kreiswirth BN, Musser JM. 2003. Correlation of acetate catabolism and growth yield in Staphylococcus aureus: implications for host-pathogen interactions. Infect Immun 71:4724-4732. http://dx.doi.org/10.1128/IAI.71.8.4724-4732.2003.
    • (2003) Infect Immun , vol.71 , pp. 4724-4732
    • Somerville, G.A.1    Said-Salim, B.2    Wickman, J.M.3    Raffel, S.J.4    Kreiswirth, B.N.5    Musser, J.M.6
  • 66
    • 0031786412 scopus 로고    scopus 로고
    • Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus
    • Chan PF, Foster SJ. 1998. Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus. J Bacteriol 180:6232-6241.
    • (1998) J Bacteriol , vol.180 , pp. 6232-6241
    • Chan, P.F.1    Foster, S.J.2
  • 67
    • 0028178609 scopus 로고
    • Regulation of alpha- and beta-hemolysins by the sar locus of Staphylococcus aureus
    • Cheung AL, Ying P. 1994. Regulation of alpha- and beta-hemolysins by the sar locus of Staphylococcus aureus. J Bacteriol 176:580-585.
    • (1994) J Bacteriol , vol.176 , pp. 580-585
    • Cheung, A.L.1    Ying, P.2
  • 68
    • 0033913836 scopus 로고    scopus 로고
    • Identification and characterization of SarH1, a new global regulator of virulence gene expression in Staphylococcus aureus
    • Tegmark K, Karlsson A, Arvidson S. 2000. Identification and characterization of SarH1, a new global regulator of virulence gene expression in Staphylococcus aureus. Mol Microbiol 37:398-409. http://dx.doi.org/10.1046/j.1365-2958.2000.02003.x.
    • (2000) Mol Microbiol , vol.37 , pp. 398-409
    • Tegmark, K.1    Karlsson, A.2    Arvidson, S.3
  • 69
    • 0036156087 scopus 로고    scopus 로고
    • Strain-dependent differences in the regulatory roles of sarA and agr in Staphylococcus aureus
    • Blevins JS, Beenken KE, Elasri MO, Hurlburt BK, Smeltzer MS. 2002. Strain-dependent differences in the regulatory roles of sarA and agr in Staphylococcus aureus. Infect Immun 70:470-480. http://dx.doi.org/10.1128/IAI.70.2.470-480.2002.
    • (2002) Infect Immun , vol.70 , pp. 470-480
    • Blevins, J.S.1    Beenken, K.E.2    Elasri, M.O.3    Hurlburt, B.K.4    Smeltzer, M.S.5
  • 70
    • 0026638833 scopus 로고
    • Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr
    • Cheung AL, Koomey JM, Butler CA, Projan SJ, Fischetti VA. 1992. Regulation of exoprotein expression in Staphylococcus aureus by a locus (sar) distinct from agr. Proc Natl Acad Sci U S A 89:6462-6466. http://dx .doi.org/10.1073/pnas.89.14.6462.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 6462-6466
    • Cheung, A.L.1    Koomey, J.M.2    Butler, C.A.3    Projan, S.J.4    Fischetti, V.A.5
  • 71
    • 0036070620 scopus 로고    scopus 로고
    • Variation in extracellular protease production among clinical isolates of Staphylococcus aureus due to different levels of expression of the protease repressor sarA
    • Karlsson A, Arvidson S. 2002. Variation in extracellular protease production among clinical isolates of Staphylococcus aureus due to different levels of expression of the protease repressor sarA. Infect Immun 70:4239-4246. http://dx.doi.org/10.1128/IAI.70.8.4239-4246.2002.
    • (2002) Infect Immun , vol.70 , pp. 4239-4246
    • Karlsson, A.1    Arvidson, S.2
  • 72
    • 0034072868 scopus 로고    scopus 로고
    • Probing the structure of RNAIII, the Staphylococcus aureus agr regulatory RNA, and identification of the RNA domain involved in repression of protein A expression
    • Benito Y, Kolb FA, Romby P, Lina G, Etienne J, Vandenesch F. 2000. Probing the structure of RNAIII, the Staphylococcus aureus agr regulatory RNA, and identification of the RNA domain involved in repression of protein A expression. RNA 6:668-679. http://dx.doi.org/10.1017 /S1355838200992550.
    • (2000) RNA , vol.6 , pp. 668-679
    • Benito, Y.1    Kolb, F.A.2    Romby, P.3    Lina, G.4    Etienne, J.5    Vandenesch, F.6
  • 74
    • 1642475071 scopus 로고    scopus 로고
    • Staphylococcus aureus capsular polysaccharides
    • O'Riordan K, Lee JC. 2004. Staphylococcus aureus capsular polysaccharides. Clin Microbiol Rev 17:218-234. http://dx.doi.org/10.1128/CMR.17.1.218-234.2004.
    • (2004) Clin Microbiol Rev , vol.17 , pp. 218-234
    • O'Riordan, K.1    Lee, J.C.2
  • 76
    • 79955471103 scopus 로고    scopus 로고
    • A play in four acts: Staphylococcus aureus abscess formation
    • Cheng AG, DeDent AC, Schneewind O, Missiakas D. 2011. A play in four acts: Staphylococcus aureus abscess formation. Trends Microbiol 19: 225-232. http://dx.doi.org/10.1016/j.tim.2011.01.007.
    • (2011) Trends Microbiol , vol.19 , pp. 225-232
    • Cheng, A.G.1    DeDent, A.C.2    Schneewind, O.3    Missiakas, D.4
  • 77
    • 84923888013 scopus 로고    scopus 로고
    • Pathogenesis of Staphylococcus aureus abscesses
    • Kobayashi SD, Malachowa N, DeLeo FR. 2015. Pathogenesis of Staphylococcus aureus abscesses. Am J Pathol 185:1518-1527. http://dx.doi.org /10.1016/j.ajpath.2014.11.030.
    • (2015) Am J Pathol , vol.185 , pp. 1518-1527
    • Kobayashi, S.D.1    Malachowa, N.2    DeLeo, F.R.3
  • 78
    • 84859858729 scopus 로고    scopus 로고
    • Immunopathogenesis of Staphylococcus aureus pulmonary infection
    • Parker D, Prince A. 2012. Immunopathogenesis of Staphylococcus aureus pulmonary infection. Semin Immunopathol 34:281-297. http://dx.doi .org/10.1007/s00281-011-0291-7.
    • (2012) Semin Immunopathol , vol.34 , pp. 281-297
    • Parker, D.1    Prince, A.2
  • 79
    • 0033836839 scopus 로고    scopus 로고
    • Nosocomial infections in combined medical-surgical intensive care units in the United States
    • Richards MJ, Edwards JR, Culver DH, Gaynes RP. 2000. Nosocomial infections in combined medical-surgical intensive care units in the United States. Infect Control Hosp Epidemiol 21:510-515. http://dx.doi.org/10.1086/501795.
    • (2000) Infect Control Hosp Epidemiol , vol.21 , pp. 510-515
    • Richards, M.J.1    Edwards, J.R.2    Culver, D.H.3    Gaynes, R.P.4
  • 80
    • 70349693475 scopus 로고    scopus 로고
    • Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues
    • Cheng AG, Kim HK, Burts ML, Krausz T, Schneewind O, Missiakas DM. 2009. Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues. FASEB J 23:3393-3404. http://dx.doi .org/10.1096/fj.09-135467.
    • (2009) FASEB J , vol.23 , pp. 3393-3404
    • Cheng, A.G.1    Kim, H.K.2    Burts, M.L.3    Krausz, T.4    Schneewind, O.5    Missiakas, D.M.6
  • 81
    • 4043059295 scopus 로고    scopus 로고
    • Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1
    • Gomez MI, Lee A, Reddy B, Muir A, Soong G, Pitt A, Cheung A, Prince A. 2004. Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1. Nat Med 10:842-848. http://dx .doi.org/10.1038/nm1079.
    • (2004) Nat Med , vol.10 , pp. 842-848
    • Gomez, M.I.1    Lee, A.2    Reddy, B.3    Muir, A.4    Soong, G.5    Pitt, A.6    Cheung, A.7    Prince, A.8
  • 82
    • 0036139401 scopus 로고    scopus 로고
    • Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung
    • Heyer G, Saba S, Adamo R, Rush W, Soong G, Cheung A, Prince A. 2002. Staphylococcus aureus agr and sarA functions are required for invasive infection but not inflammatory responses in the lung. Infect Immun 70:127-133. http://dx.doi.org/10.1128/IAI.70.1.127-133.2002.
    • (2002) Infect Immun , vol.70 , pp. 127-133
    • Heyer, G.1    Saba, S.2    Adamo, R.3    Rush, W.4    Soong, G.5    Cheung, A.6    Prince, A.7
  • 83
    • 54949140792 scopus 로고    scopus 로고
    • Alpha-toxin facilitates the generation ofCXCchemokine gradients and stimulates neutrophil homing in Staphylococcus aureus pneumonia
    • Bartlett AH, Foster TJ, Hayashida A, Park PW. 2008. Alpha-toxin facilitates the generation ofCXCchemokine gradients and stimulates neutrophil homing in Staphylococcus aureus pneumonia. J Infect Dis 198: 1529-1535. http://dx.doi.org/10.1086/592758.
    • (2008) J Infect Dis , vol.198 , pp. 1529-1535
    • Bartlett, A.H.1    Foster, T.J.2    Hayashida, A.3    Park, P.W.4
  • 84
    • 0032858909 scopus 로고    scopus 로고
    • Alpha-toxin damages the air-blood barrier of the lung in a rat model of Staphylococcus aureus-induced pneumonia
    • McElroy MC, Harty HR, Hosford GE, Boylan GM, Pittet JF, Foster TJ. 1999. Alpha-toxin damages the air-blood barrier of the lung in a rat model of Staphylococcus aureus-induced pneumonia. Infect Immun 67:5541-5544.
    • (1999) Infect Immun , vol.67 , pp. 5541-5544
    • McElroy, M.C.1    Harty, H.R.2    Hosford, G.E.3    Boylan, G.M.4    Pittet, J.F.5    Foster, T.J.6
  • 85
    • 0035979248 scopus 로고    scopus 로고
    • Structural rationale for the modulation of abscess formation by Staphylococcus aureus capsular polysaccharides
    • Tzianabos AO, Wang JY, Lee JC. 2001. Structural rationale for the modulation of abscess formation by Staphylococcus aureus capsular polysaccharides. Proc Natl Acad Sci U S A 98:9365-9370. http://dx.doi.org/10.1073/pnas.161175598.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 9365-9370
    • Tzianabos, A.O.1    Wang, J.Y.2    Lee, J.C.3
  • 86
    • 19744370660 scopus 로고    scopus 로고
    • Staphylococcus aureus strains that express serotype 5 or serotype 8 capsular polysaccharides differ in virulence
    • Watts A, Ke D, Wang Q, Pillay A, Nicholson-Weller A, Lee JC. 2005. Staphylococcus aureus strains that express serotype 5 or serotype 8 capsular polysaccharides differ in virulence. Infect Immun 73:3502-3511. http://dx .doi.org/10.1128/IAI.73.6.3502-3511.2005.
    • (2005) Infect Immun , vol.73 , pp. 3502-3511
    • Watts, A.1    Ke, D.2    Wang, Q.3    Pillay, A.4    Nicholson-Weller, A.5    Lee, J.C.6
  • 87
    • 84864822520 scopus 로고    scopus 로고
    • CodY deletion enhances in vivo virulence of communityassociated methicillin-resistant Staphylococcus aureus clone USA300
    • Montgomery CP, Boyle-Vavra S, Roux A, Ebine K, Sonenshein AL, Daum RS. 2012. CodY deletion enhances in vivo virulence of communityassociated methicillin-resistant Staphylococcus aureus clone USA300. Infect Immun 80:2382-2389. http://dx.doi.org/10.1128/IAI.06172-11.
    • (2012) Infect Immun , vol.80 , pp. 2382-2389
    • Montgomery, C.P.1    Boyle-Vavra, S.2    Roux, A.3    Ebine, K.4    Sonenshein, A.L.5    Daum, R.S.6
  • 89
    • 0036175120 scopus 로고    scopus 로고
    • In vitro serial passage of Staphylococcus aureus: changes in physiology, virulence factor production, and agr nucleotide sequence
    • Somerville GA, Beres SB, Fitzgerald JR, DeLeo FR, Cole RL, Hoff JS, Musser JM. 2002. In vitro serial passage of Staphylococcus aureus: changes in physiology, virulence factor production, and agr nucleotide sequence. J Bacteriol 184:1430-1437. http://dx.doi.org/10.1128/JB.184.5.1430-1437.2002.
    • (2002) J Bacteriol , vol.184 , pp. 1430-1437
    • Somerville, G.A.1    Beres, S.B.2    Fitzgerald, J.R.3    DeLeo, F.R.4    Cole, R.L.5    Hoff, J.S.6    Musser, J.M.7
  • 90
    • 0343052949 scopus 로고    scopus 로고
    • Gene replacement in Staphylococcus carnosus and Staphylococcus xylosus
    • Brückner R. 1997. Gene replacement in Staphylococcus carnosus and Staphylococcus xylosus. FEMS Microbiol Lett 151:1-8. http://dx.doi.org /10.1016/S0378-1097(97)00116-X.
    • (1997) FEMS Microbiol Lett , vol.151 , pp. 1-8
    • Brückner, R.1

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