Loss of Macrophage Low-Density Lipoprotein Receptor-Related Protein 1 Confers Resistance to the Antiatherogenic Effects of Tumor Necrosis Factor-α Inhibition

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 36, Issue 8, 2016, Pages 1483-1495

  Zhu, Lin ^a,c   Giunzioni, Ilaria ^d   Tavori, Hagai ^d   Covarrubias, Roman ^a   Ding, Lei ^a   Zhang, Youmin ^a   Ormseth, Michelle ^b   Major, Amy S ^a   Stafford, John M ^a,c   Linton, MacRae F ^a   Fazio, Sergio ^d  

^a Division of Rheumatology   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^c Tennessee Valley Healthcare System   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

atherosclerosis; inflammation; low density lipoprotein receptor related protein 1; macrophages; tumor necrosis factor alpha

Indexed keywords

ADALIMUMAB; APOLIPOPROTEIN E; CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; ANTIINFLAMMATORY AGENT; LOW DENSITY LIPOPROTEIN RECEPTOR; LRP1 PROTEIN, MOUSE; LY ANTIGEN; LY-6C ANTIGEN, MOUSE; TUMOR NECROSIS FACTOR; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; CELL MIGRATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HYPERLIPIDEMIA; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; WILD TYPE; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; AORTIC DISEASES; APOPTOSIS; ATHEROSCLEROTIC PLAQUE; BONE MARROW TRANSPLANTATION; CELL MOTION; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; DRUG RESISTANCE; GENETIC PREDISPOSITION; GENETICS; KNOCKOUT MOUSE; LIPID DIET; METABOLISM; MONOCYTE; NECROSIS; PATHOLOGY; PHENOTYPE; SIGNAL TRANSDUCTION; WHOLE BODY RADIATION;

ADALIMUMAB; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIGENS, LY; AORTA; AORTIC DISEASES; APOLIPOPROTEINS E; APOPTOSIS; ATHEROSCLEROSIS; BONE MARROW TRANSPLANTATION; CELL MOVEMENT; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DRUG RESISTANCE; FEMALE; GENETIC PREDISPOSITION TO DISEASE; MACROPHAGES; MICE, KNOCKOUT; MONOCYTES; NECROSIS; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; RECEPTORS, LDL; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEINS; WHOLE-BODY IRRADIATION;

EID: 84976573510     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.116.307736     Document Type: Article

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