Nanoemulsion as a potential ophthalmic delivery system for dorzolamide hydrochloride

AAPS PharmSciTech

Volumn 10, Issue 3, 2009, Pages 808-819

  Ammar, Hussein O ^a   Salama, H A ^a   Ghorab, M ^b   Mahmoud, A A ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Dorzolamide hydrochloride; Glaucoma; Nanoemulsion; Pharmacodynamic; Physicochemical characterization

Indexed keywords

COSURFACTANT; CREMOPHOR; DIETHYLENE GLYCOL MONOETHYL ETHER; DORZOLAMIDE; MIGLYOL; MIRANOL; MYRISTIC ACID ISOPROPYL ESTER; POLYSORBATE 80; PROPYLENE GLYCOL; TRIACETIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG RELEASE; EYE IRRITATION; HISTOLOGY; MALE; NANOEMULSION; NONHUMAN; PHYSICAL CHEMISTRY; RABBIT;

ANIMALS; AQUEOUS HUMOR; CARBONIC ANHYDRASE INHIBITORS; CORNEA; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EMULSIONS; EYE DISEASES; GLAUCOMA; HYDROGEN-ION CONCENTRATION; IRRITANTS; MALE; NANOPARTICLES; OPHTHALMIC SOLUTIONS; OSMOLAR CONCENTRATION; PARTICLE SIZE; RABBITS; RHEOLOGY; SOLUBILITY; SULFONAMIDES; SURFACE TENSION; THIOPHENES; VISCOSITY;

EID: 70449522160     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-009-9268-4     Document Type: Article

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