Design of cationic lipid nanoparticles for ocular delivery: Development, characterization and cytotoxicity

International Journal of Pharmaceutics

Volumn 461, Issue 1-2, 2014, Pages 64-73

  Fangueiro, Joana F ^a   Andreani, Tatiana ^a,b,c   Egea, Maria A ^d   Garcia, Maria L ^d   Souto, Selma B ^e   Silva, Amélia M ^b,c   Souto, Eliana B ^a,c  

^a UNIVERSIDADE FERNANDO PESSOA   (Portugal)

^b UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^c UNIVERSITY OF TRÁS OS MONTES AND ALTO DOURO   (Portugal)

^d UNIVERSITY OF BARCELONA   (Spain)

^e HOSPITAL DE BRAGA   (Portugal)

Author keywords

Cytotoxicity; Lipid nanoparticles; Multiple emulsion; Ocular delivery; Turbiscan; Y 79 human retinoblastoma cells

Indexed keywords

CATIONIC LIPID NANOPARTICLE; CETRIMIDE; EMULSIFYING AGENT; PHOSPHATIDYLCHOLINE; POLOXAMER; SOLID LIPID NANOPARTICLE; UNCLASSIFIED DRUG; CATION; DRUG CARRIER; EMULSION; LIPID; NANOPARTICLE;

ARTICLE; BIOAVAILABILITY; CHEMICAL PARAMETERS; CONTROLLED STUDY; CRYSTALLIZATION; CYTOTOXICITY; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; EMULSION; FACTORIAL DESIGN; HUMAN; HUMAN CELL; INTRAOCULAR DRUG ADMINISTRATION; MUCOADHESION; NANOENCAPSULATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RETINOBLASTOMA; TOXICITY TESTING; ADVERSE EFFECTS; CHEMISTRY; DRUG DELIVERY SYSTEM; DRUG STABILITY; MEDICINAL CHEMISTRY; METABOLISM; PROCEDURES; TUMOR CELL LINE;

ADMINISTRATION, OPHTHALMIC; CATIONS; CELL LINE, TUMOR; CETRIMONIUM COMPOUNDS; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EMULSIONS; HUMANS; LIPIDS; NANOPARTICLES; RETINOBLASTOMA; TOXICITY TESTS;

EID: 84889593525     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.11.025     Document Type: Article

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