Design and optimization of topical methotrexate loaded niosomes for enhanced management of psoriasis: Application of Box-Behnken design, in-vitro evaluation and in-vivo skin deposition study

International Journal of Pharmaceutics

Volumn 485, Issue 1-2, 2015, Pages 235-243

  Abdelbary, Aly A ^a   Aboughaly, Mohamed H H ^a  

^a CAIRO UNIVERSITY   (Egypt)

Author keywords

Box Behnken; In vivo histopathological study; In vivo skin deposition; Methotrexate; Niosomes

Indexed keywords

CHOLESTEROL; IONIC SURFACTANT; METHOTREXATE; NIOSOME; DERMATOLOGICAL AGENT; DICETYL PHOSPHATE; DRUG CARRIER; HEXOSE; LIPOSOME; ORGANOPHOSPHATE; SORBITAN STEARATE; SURFACTANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BOX BEHNKEN DESIGN; CONTROLLED STUDY; DRUG FORMULATION; DRUG SAFETY; DRUG SCREENING; DRUG SOLUBILITY; DRUG SOLUTION; ENCAPSULATION; EXPERIMENTAL DESIGN; FILM HYDRATION TECHNIQUE; HISTOPATHOLOGY; HYDRATION; IN VIVO SKIN DEPOSITION; MALE; MORPHOLOGY; NONHUMAN; PARTICLE SIZE; PHARMACOLOGICAL PROCEDURES; PRIORITY JOURNAL; PSORIASIS; RAT; SIGNAL NOISE RATIO; STRATUM CORNEUM; TRANSMISSION ELECTRON MICROSCOPY; ULTRASOUND; ZETA POTENTIAL; ANIMAL; AREA UNDER THE CURVE; CHEMISTRY; INTRADERMAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; NANOTECHNOLOGY; PHARMACEUTICS; PROCEDURES; SKIN; SKIN ABSORPTION; SOLUBILITY; STATISTICAL MODEL; SURFACE PROPERTY; WISTAR RAT;

ADMINISTRATION, CUTANEOUS; ANIMALS; AREA UNDER CURVE; CHEMISTRY, PHARMACEUTICAL; CHOLESTEROL; DERMATOLOGIC AGENTS; DRUG CARRIERS; HEXOSES; LIPOSOMES; MALE; METHOTREXATE; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, STATISTICAL; NANOTECHNOLOGY; ORGANOPHOSPHATES; PARTICLE SIZE; PSORIASIS; RATS, WISTAR; SKIN; SKIN ABSORPTION; SOLUBILITY; SURFACE PROPERTIES; SURFACE-ACTIVE AGENTS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84925037689     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2015.03.020     Document Type: Article

References (46)

1. G. Abdelbary Ocular ciprofloxacin hydrochloride mucoadhesive chitosan-coated liposomes Pharm. Dev. Technol. 16 2011 44 56
2. H. Abdelkader, S. Ismail, A. Kamal, and R.G. Alany Preparation of niosomes as an ocular delivery system for naltrexone hydrochloride: physicochemical characterization Pharmazie 65 2010 811 817
3. W. Abraham, and D.T. Downing Interaction between corneocytes and stratum corneum lipid liposomes in vitro Biochim. Biophys. Acta. 1021 1990 119 125
4. R. Agarwal, O.P. Katare, and S.P. Vyas Preparation and in vitro evaluation of liposomal/niosomal delivery systems for antipsoriatic drug dithranol Int. J. Pharm. 228 2001 43 52
5. G.G. Agyralides, P.P. Dallas, and D.M. Rekkas Development and in vitro evaluation of furosemide transdermal formulations using experimental design techniques Int. J. Pharm. 281 2004 35 43
6. A.M. Al-Mahallawi, O.M. Khowessah, and R.A. Shoukri Nano-transfersomal ciprofloxacin loaded vesicles for non-invasive trans-tympanic ototopical delivery: in-vitro optimization ex-vivo permeation studies, and in-vivo assessment Int. J. Pharm. 472 2014 304 314
7. G. Annadurai, L.Y. Ling, and J.F. Lee Statistical optimization of medium components and growth conditions by response surface methodology to enhance phenol degradation by Pseudomonas putida J. Hazard. Mater. 151 2008 171 178
8. A.J. Baillie, A.T. Florence, L.R. Hume, G.T. Muirhead, and A. Rogerson The preparation and properties of niosomes-non-ionic surfactant vesicles J. Pharm. Pharmacol. 37 1985 863 868
9. P. Balakrishnan, S. Shanmugam, W.S. Lee, W.M. Lee, J.O. Kim, D.H. Oh, D.D. Kim, J.S. Kim, B.K. Yoo, H.G. Choi, J.S. Woo, and C.S. Yong Formulation and in vitro assessment of minoxidil niosomes for enhanced skin delivery Int. J. Pharm. 377 2009 1 8
10. J.D. Bancroft, and M. Gamble Theory and practice of histological techniques 6th ed. 2008 Churchill Livingstone/Elsevier Philadelphia PA
11. E. Begas, C. Papandreou, A. Tsakalof, D. Daliani, G. Papatsibas, and E. Asprodini Simple and reliable HPLC method for the monitoring of methotrexate in osteosarcoma patients J. Chromatogr. Sci. 52 2014 590 595
12. E.R. Bendas, and A.A. Abdelbary Instantaneous enteric nano-encapsulation of omeprazole: pharmaceutical and pharmacological evaluation Int. J. Pharm. 468 2014 97 104
13. H. Chaudhary, K. Kohli, and V. Kumar Nano-transfersomes as a novel carrier for transdermal delivery Int. J. Pharm. 454 2013 367 380
14. B. Chauhan, and R. Gupta Application of statistical experimental design for optimization of alkaline protease production from Bacillus sp. RGR-14 Process Biochem. 39 2004 2115 2122
15. S. Chopra, G.V. Patil, and S.K. Motwani Release modulating hydrophilic matrix systems of losartan potassium: optimization of formulation using statistical experimental design Eur. J. Pharm. Biopharm. 66 2007 73 82
16. R.A. Clark Gone but not forgotten: lesional memory in psoriatic skin J. Invest. Dermatol. 131 2011 283 285
17. L.S. de Lima, M.D.M. Araujo, S.P. Quináia, D.W. Migliorine, and J.R. Garcia Adsorption modeling of Cr, Cd and Cu on activated carbon of different origins by using fractional factorial design Chem. Eng. J. 166 2011 881 889
18. L. Di Marzio, C. Marianecci, M. Petrone, F. Rinaldi, and M. Carafa Novel pH-sensitive non-ionic surfactant vesicles: comparison between Tween 21 and Tween 20 Colloid Surf. B. Biointerfaces 82 2011 18 24
19. M.S. El-Samaligy, N.N. Afifi, and E.A. Mahmoud Increasing bioavailability of silymarin using a buccal liposomal delivery system: preparation and experimental design investigation Int. J. Pharm. 308 2006 140 148
20. G. Goyal, T. Garg, B. Malik, G. Chauhan, G. Rath, and A.K. Goyal Development and characterization of niosomal gel for topical delivery of benzoyl peroxide Drug. Deliv. 2013
21. T. Ichino, T. Yotsuyanagi, I. Mizuno, Y. Akamo, T. Yamamoto, T. Saito, S. Kurahashi, N. Tanimoto, and J. Yura Antitumor effect of liposome-entrapped adriamycin administered via the portal vein Jpn. J. Cancer. Res. 81 1990 1052 1056
22. R. Kaushik, S. Saran, J. Isar, and R.K. Saxena Statistical optimization of medium components and growth conditions by response surface methodology to enhance lipase production by Aspergillus carneus J. Mol. Catal. B: Enzym. 40 2006 121 126
23. K.M. Kazi, A.S. Mandal, N. Biswas, A. Guha, S. Chatterjee, M. Behera, and K. Kuotsu Niosome: a future of targeted drug delivery systems J. Adv. Pharm. Technol. Res. 1 2010 374 380
24. J.M. Kremer, M.E. Weinblatt, A.D. Bankhurst, K.J. Bulpitt, R.M. Fleischmann, C.G. Jackson, K.M. Atkins, A. Feng, and D.J. Burge Etanercept added to background methotrexate therapy in patients with rheumatoid arthritis: continued observations Arthritis Rheum. 48 2003 1493 1499
25. P.K. Lakshmi, G.S. Devi, S. Bhaskaran, and S. Sacchidanand Niosomal methotrexate gel in the treatment of localized psoriasis: phase I and phase II studies Indian. J. Dermatol. Venereol. Leprol. 73 2007 157 161
26. C. Marianecci, F. Rinaldi, M. Mastriota, S. Pieretti, E. Trapasso, D. Paolino, and M. Carafa Anti-inflammatory activity of novel ammonium glycyrrhizinate/niosomes delivery system: human and murine models J. Control. Release 164 2012 17 25
27. M. Mokhtar, O.A. Sammour, M.A. Hammad, and N.A. Megrab Effect of some formulation parameters on flurbiprofen encapsulation and release rates of niosomes prepared from proniosomes Int. J. Pharm. 361 2008 104 111
28. K. Moribe, K. Maruyama, and M. Iwatsuru Encapsulation characteristics of nystatin in liposomes: effects of cholesterol and polyethylene glycol derivatives Int. J. Pharm. 188 1999 193 202
29. N.M. Morsi, G.A. Abdelbary, and M.A. Ahmed Silver sulfadiazine based cubosome hydrogels for topical treatment of burns: development and in vitro/in vivo characterization Eur. J. Pharm. Biopharm. 86 2014 178 189
30. R.H. Muller, C. Jacobs, and O. Kayser Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future Adv. Drug. Deliv. Rev. 47 2001 3 19
31. D. Paolino, R. Muzzalupo, A. Ricciardi, C. Celia, N. Picci, and M. Fresta In vitro and in vivo evaluation of Bola-surfactant containing niosomes for transdermal delivery Biomed. Microdevices 9 2007 421 433
32. K. Ruckmani, and V. Sankar Formulation and optimization of Zidovudine niosomes AAPS PharmSciTech 11 2010 1119 1127
33. A. Sankhyan, and P.K. Pawar Metformin loaded non-ionic surfactant vesicles: optimization of formulation, effect of process variables and characterization Daru 21 2013 7
34. A. Shahiwala, and A. Misra Studies in topical application of niosomally entrapped Nimesulide J. Pharm. Pharm. Sci. 5 2002 220 225
35. M.A. Shatalebi, S.A. Mostafavi, and A. Moghaddas Niosome as a drug carrier for topical delivery of N-acetyl glucosamine Res. Pharm. Sci. 5 2010 107 117
36. L.N. Shen, Y.T. Zhang, Q. Wang, L. Xu, and N.P. Feng Enhanced in vitro and in vivo skin deposition of apigenin delivered using ethosomes Int. J. Pharm. 460 2014 280 288
37. J.R. Sullivan Treatments for severe psoriasis Aust. Prescr. 32 2009 14 18
38. N. Udupa, K.S. Chandraprakash, P. Umadevi, and G.K. Pillai Formulation and evaluation of methotrexate niosomes Drug. Dev. Ind. Pharm. 19 1993 1331 1342
39. R. Vaidyanathan, M.G. Chaubal, and R.C. Vasavada Effect of pH and solubility on in vitro skin penetration of methotrexate from a 50% v/v propylene glycol-water vehicle Int. J. Pharm. 25 1985 85 93
40. D.D. Verma, S. Verma, G. Blume, and A. Fahr Particle size of liposomes influences dermal delivery of substances into skin Int. J. Pharm. 258 2003 141 151
41. J. Wang, N.M. Plourde, N. Iverson, P.V. Moghe, and K.E. Uhrich Nanoscale amphiphilic macromolecules as lipoprotein inhibitors: the role of charge and architecture Int. J. Nanomed. 2 2007 697 705
42. Z. Wang, and X. He Dynamics of vesicle formation from lipid droplets: mechanism and controllability J. Chem. Phys. 130 2009 094905
43. G.D. Weinstein, J.L. McCullough, and E. Olsen Topical methotrexate therapy for psoriasis Arch. Dermatol. 125 1989 227 230
44. Y. Yazici, T. Sokka, H. Kautiainen, C. Swearingen, I. Kulman, and T. Pincus Long term safety of methotrexate in routine clinical care: discontinuation is unusual and rarely the result of laboratory abnormalities Ann. Rheum. Dis. 64 2005 207 211
45. L.C. Zaba, I. Cardinale, P. Gilleaudeau, M. Sullivan-Whalen, M. Suarez-Farinas, J. Fuentes-Duculan, I. Novitskaya, A. Khatcherian, M.J. Bluth, M.A. Lowes, and J.G. Krueger Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses J. Exp. Med. 204 2007 3183 3194
46. R.M. Zaki, A.A. Ali, S.F. El Menshawe, and A. AbdelBary Formulation and in vitro evaluation of diacerein loaded niosomes Int. J. Pharm. Pharm. Sci. 6 2014 515 521