Missing heritability of complex diseases: Enlightenment by genetic variants from intermediate phenotypes

BioEssays

Volumn 38, Issue 7, 2016, Pages 664-673

  Blanco Gómez, Adrián ^a,b   Castillo Lluva, Sonia ^a,b,d   del Mar Sáez Freire, María ^a,b   Hontecillas Prieto, Lourdes ^a,b,e   Mao, Jian Hua ^c   Castellanos Martín, Andrés ^a,b,f   Pérez Losada, Jesus ^a,b  

^a CSIC   (Spain)

^b INSTITUTO DE INVESTIGACIÓN BIOMÉDICA DE SALAMANCA IBSAL   (Spain)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^e Instituto de Biomedicina de Sevilla   (Spain)

^f INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

Author keywords

complex diseases; heritability; intermediate phenotype or endophenotype; missing heritability

Indexed keywords

ARTICLE; COMPLEX DISEASE; ENDOPHENOTYPE; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC TRAIT; GENOME-WIDE ASSOCIATION STUDY; HEREDITY; HERITABILITY; HUMAN; NONHUMAN; PATHOGENESIS; PHENOTYPE; PHENOTYPIC VARIATION; PHYSICAL DISEASE BY ETIOLOGY AND PATHOGENESIS; RARE DISEASE;

EID: 84976543884     PISSN: 02659247     EISSN: 15211878     Source Type: Journal    
DOI: 10.1002/bies.201600084     Document Type: Article

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