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Volumn 64, Issue 1, 2016, Pages 277-286

The hepatic, biliary, and pancreatic network of stem/progenitor cell niches in humans: A new reference frame for disease and regeneration

Author keywords

[No Author keywords available]

Indexed keywords

AMPULLA OF VATER; ANATOMIC LANDMARK; ARTICLE; BILE DUCT; CELL DIFFERENTIATION; CELL DIVISION; CELL LINEAGE; CELLS BY BODY ANATOMY; CHOLANGIOCYTE; CHRONIC LIVER DISEASE; DIABETES MELLITUS; EXTRACELLULAR MATRIX; HEPATOBILIARY SYSTEM; IMMUNOGLOBULIN G4 RELATED DISEASE; IN VITRO STUDY; INTRAHEPATIC BILE DUCT; LIVER; LIVER CELL; LIVER CIRRHOSIS; LIVER REGENERATION; ORGANOGENESIS; PANCREAS; PANCREAS ISLET; PANCREAS ISLET CELL; PANCREATIC DUCT; PHENOTYPE; PRIORITY JOURNAL; SENESCENCE; STEM CELL; STEM CELL NICHE; TISSUE REGENERATION; TURNOVER TIME;

EID: 84976489438     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.28326     Document Type: Article
Times cited : (121)

References (53)
  • 2
    • 57349112286 scopus 로고    scopus 로고
    • Generation and regeneration of cells of the liver and pancreas
    • Zaret KS, Grompe M. Generation and regeneration of cells of the liver and pancreas. Science 2008;322:1490-1494.
    • (2008) Science , vol.322 , pp. 1490-1494
    • Zaret, K.S.1    Grompe, M.2
  • 3
    • 45849089573 scopus 로고    scopus 로고
    • Embryology of extra- and intrahepatic bile ducts, the ductal plate
    • Roskams T, Desmet V. Embryology of extra- and intrahepatic bile ducts, the ductal plate. Anat Rec (Hoboken) 2008;291:628-635.
    • (2008) Anat Rec (Hoboken) , vol.291 , pp. 628-635
    • Roskams, T.1    Desmet, V.2
  • 4
    • 80053610191 scopus 로고    scopus 로고
    • Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells
    • Carpentier R, Suner RE, Van Hul N, Kopp JL, Beaudry JB, Cordi S, et al. Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology 2011;141:1432-1438.
    • (2011) Gastroenterology , vol.141 , pp. 1432-1438
    • Carpentier, R.1    Suner, R.E.2    Van Hul, N.3    Kopp, J.L.4    Beaudry, J.B.5    Cordi, S.6
  • 5
    • 67650246360 scopus 로고    scopus 로고
    • Sox17 regulates organ lineage segregation of ventral foregut progenitor cells
    • Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, et al. Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell 2009;17:62-74.
    • (2009) Dev Cell , vol.17 , pp. 62-74
    • Spence, J.R.1    Lange, A.W.2    Lin, S.C.3    Kaestner, K.H.4    Lowy, A.M.5    Kim, I.6
  • 6
    • 84055193971 scopus 로고    scopus 로고
    • Pancreatic ductal cells in development, regeneration, and neoplasia
    • Reichert M, Rustgi AK. Pancreatic ductal cells in development, regeneration, and neoplasia. J Clin Invest 2011;121:4572-4578.
    • (2011) J Clin Invest , vol.121 , pp. 4572-4578
    • Reichert, M.1    Rustgi, A.K.2
  • 7
    • 82455168059 scopus 로고    scopus 로고
    • Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets
    • Cardinale V, Wang Y, Carpino G, Cui CB, Gatto M, Rossi M, et al. Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets. Hepatology 2011;54:2159-2172.
    • (2011) Hepatology , vol.54 , pp. 2159-2172
    • Cardinale, V.1    Wang, Y.2    Carpino, G.3    Cui, C.B.4    Gatto, M.5    Rossi, M.6
  • 8
    • 84855417413 scopus 로고    scopus 로고
    • Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages
    • Carpino G, Cardinale V, Onori P, Franchitto A, Berloco PB, Rossi M, et al. Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages. J Anat 2012;220:186-199.
    • (2012) J Anat , vol.220 , pp. 186-199
    • Carpino, G.1    Cardinale, V.2    Onori, P.3    Franchitto, A.4    Berloco, P.B.5    Rossi, M.6
  • 10
    • 84885115832 scopus 로고    scopus 로고
    • Biliary tree stem cells, precursors to pancreatic committed progenitors: evidence for possible life-long pancreatic organogenesis
    • Wang Y, Lanzoni G, Carpino G, Cui CB, Dominguez-Bendala J, Wauthier E, et al. Biliary tree stem cells, precursors to pancreatic committed progenitors: evidence for possible life-long pancreatic organogenesis. Stem Cells 2013;31:1966-1979.
    • (2013) Stem Cells , vol.31 , pp. 1966-1979
    • Wang, Y.1    Lanzoni, G.2    Carpino, G.3    Cui, C.B.4    Dominguez-Bendala, J.5    Wauthier, E.6
  • 11
    • 84901239385 scopus 로고    scopus 로고
    • Evidence for multipotent endodermal stem/progenitor cell populations in human gallbladder
    • Carpino G, Cardinale V, Gentile R, Onori P, Semeraro R, Franchitto A, et al. Evidence for multipotent endodermal stem/progenitor cell populations in human gallbladder. J Hepatol 2014;60:1194-1202.
    • (2014) J Hepatol , vol.60 , pp. 1194-1202
    • Carpino, G.1    Cardinale, V.2    Gentile, R.3    Onori, P.4    Semeraro, R.5    Franchitto, A.6
  • 12
    • 84887976409 scopus 로고    scopus 로고
    • Concise review: clinical programs of stem cell therapies for liver and pancreas
    • Lanzoni G, Oikawa T, Wang Y, Cui CB, Carpino G, Cardinale V, et al. Concise review: clinical programs of stem cell therapies for liver and pancreas. Stem Cells 2013;31:2047-2060.
    • (2013) Stem Cells , vol.31 , pp. 2047-2060
    • Lanzoni, G.1    Oikawa, T.2    Wang, Y.3    Cui, C.B.4    Carpino, G.5    Cardinale, V.6
  • 13
    • 84877106062 scopus 로고    scopus 로고
    • Sox9 and programming of liver and pancreatic progenitors
    • Kawaguchi Y. Sox9 and programming of liver and pancreatic progenitors. J Clin Invest 2013;123:1881-1886.
    • (2013) J Clin Invest , vol.123 , pp. 1881-1886
    • Kawaguchi, Y.1
  • 14
    • 84884978675 scopus 로고    scopus 로고
    • Identification of intramural epithelial networks linked to peribiliary glands that express progenitor cell markers and proliferate after injury in mice
    • Dipaola F, Shivakumar P, Pfister J, Walters S, Sabla G, Bezerra JA. Identification of intramural epithelial networks linked to peribiliary glands that express progenitor cell markers and proliferate after injury in mice. Hepatology 2013;58:1486-1496.
    • (2013) Hepatology , vol.58 , pp. 1486-1496
    • Dipaola, F.1    Shivakumar, P.2    Pfister, J.3    Walters, S.4    Sabla, G.5    Bezerra, J.A.6
  • 15
    • 84881606187 scopus 로고    scopus 로고
    • Recent advances in the morphological and functional heterogeneity of the biliary epithelium
    • Han Y, Glaser S, Meng F, Francis H, Marzioni M, McDaniel K, et al. Recent advances in the morphological and functional heterogeneity of the biliary epithelium. Exp Biol Med (Maywood) 2013;238:549-565.
    • (2013) Exp Biol Med (Maywood) , vol.238 , pp. 549-565
    • Han, Y.1    Glaser, S.2    Meng, F.3    Francis, H.4    Marzioni, M.5    McDaniel, K.6
  • 16
    • 84945487651 scopus 로고    scopus 로고
    • Activation of biliary tree stem cells within peribiliary glands in primary sclerosing cholangitis
    • Carpino G, Cardinale V, Renzi A, Hov JR, Berloco PB, Rossi M, et al. Activation of biliary tree stem cells within peribiliary glands in primary sclerosing cholangitis. J Hepatol 2015.
    • (2015) J Hepatol
    • Carpino, G.1    Cardinale, V.2    Renzi, A.3    Hov, J.R.4    Berloco, P.B.5    Rossi, M.6
  • 17
    • 84890927337 scopus 로고    scopus 로고
    • Proposal of a new disease concept “biliary diseases with pancreatic counterparts.” Anatomical and pathological bases
    • Nakanuma Y, Harada K, Sasaki M, Sato Y. Proposal of a new disease concept “biliary diseases with pancreatic counterparts.” Anatomical and pathological bases. Histol Histopathol 2014;29:1-10.
    • (2014) Histol Histopathol , vol.29 , pp. 1-10
    • Nakanuma, Y.1    Harada, K.2    Sasaki, M.3    Sato, Y.4
  • 18
    • 84932154584 scopus 로고    scopus 로고
    • Fas/Fas ligand apoptosis pathway underlies immunomodulatory properties of human biliary tree stem/progenitor cells
    • Riccio M, Carnevale G, Cardinale V, Gibellini L, De Biasi S, Pisciotta A, et al. Fas/Fas ligand apoptosis pathway underlies immunomodulatory properties of human biliary tree stem/progenitor cells. J Hepatol 2014;61:1097-1105.
    • (2014) J Hepatol , vol.61 , pp. 1097-1105
    • Riccio, M.1    Carnevale, G.2    Cardinale, V.3    Gibellini, L.4    De Biasi, S.5    Pisciotta, A.6
  • 19
    • 84901243818 scopus 로고    scopus 로고
    • Injury to peribiliary glands and vascular plexus before liver transplantation predicts formation of non-anastomotic biliary strictures
    • op den Dries S, Westerkamp AC, Karimian N, Gouw AS, Bruinsma BG, Markmann JF, et al. Injury to peribiliary glands and vascular plexus before liver transplantation predicts formation of non-anastomotic biliary strictures. J Hepatol 2014;60:1172-1179.
    • (2014) J Hepatol , vol.60 , pp. 1172-1179
    • op den Dries, S.1    Westerkamp, A.C.2    Karimian, N.3    Gouw, A.S.4    Bruinsma, B.G.5    Markmann, J.F.6
  • 20
    • 84899729602 scopus 로고    scopus 로고
    • Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming
    • Miyajima A, Tanaka M, Itoh T. Stem/progenitor cells in liver development, homeostasis, regeneration, and reprogramming. Cell Stem Cell 2014;14:561-574.
    • (2014) Cell Stem Cell , vol.14 , pp. 561-574
    • Miyajima, A.1    Tanaka, M.2    Itoh, T.3
  • 23
    • 84920989984 scopus 로고    scopus 로고
    • Long-term culture of genome-stable bipotent stem cells from adult human liver
    • Huch M, Gehart H, van Boxtel R, Hamer K, Blokzijl F, Verstegen MM, et al. Long-term culture of genome-stable bipotent stem cells from adult human liver. Cell 2015;160:299-312.
    • (2015) Cell , vol.160 , pp. 299-312
    • Huch, M.1    Gehart, H.2    van Boxtel, R.3    Hamer, K.4    Blokzijl, F.5    Verstegen, M.M.6
  • 25
    • 84939216194 scopus 로고    scopus 로고
    • Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer
    • Font-Burgada J, Shalapour S, Ramaswamy S, Hsueh B, Rossell D, Umemura A, et al. Hybrid periportal hepatocytes regenerate the injured liver without giving rise to cancer. Cell 2015;162:766-779.
    • (2015) Cell , vol.162 , pp. 766-779
    • Font-Burgada, J.1    Shalapour, S.2    Ramaswamy, S.3    Hsueh, B.4    Rossell, D.5    Umemura, A.6
  • 26
    • 78651228289 scopus 로고    scopus 로고
    • Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
    • Furuyama K, Kawaguchi Y, Akiyama H, Horiguchi M, Kodama S, Kuhara T, et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet 2011;43:34-41.
    • (2011) Nat Genet , vol.43 , pp. 34-41
    • Furuyama, K.1    Kawaguchi, Y.2    Akiyama, H.3    Horiguchi, M.4    Kodama, S.5    Kuhara, T.6
  • 27
    • 84055199890 scopus 로고    scopus 로고
    • Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration
    • Malato Y, Naqvi S, Schurmann N, Ng R, Wang B, Zape J, et al. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. J Clin Invest 2011;121:4850-4860.
    • (2011) J Clin Invest , vol.121 , pp. 4850-4860
    • Malato, Y.1    Naqvi, S.2    Schurmann, N.3    Ng, R.4    Wang, B.5    Zape, J.6
  • 28
    • 84938097216 scopus 로고    scopus 로고
    • Paradoxes in studies of liver regeneration: relevance of the parable of the blind men and the elephant
    • Reid LM. Paradoxes in studies of liver regeneration: relevance of the parable of the blind men and the elephant. Hepatology 2015;62:330-333.
    • (2015) Hepatology , vol.62 , pp. 330-333
    • Reid, L.M.1
  • 29
    • 84925092021 scopus 로고    scopus 로고
    • Adult hepatocytes are generated by self-duplication rather than stem cell differentiation
    • Yanger K, Knigin D, Zong Y, Maggs L, Gu G, Akiyama H, et al. Adult hepatocytes are generated by self-duplication rather than stem cell differentiation. Cell Stem Cell 2014;15:340-349.
    • (2014) Cell Stem Cell , vol.15 , pp. 340-349
    • Yanger, K.1    Knigin, D.2    Zong, Y.3    Maggs, L.4    Gu, G.5    Akiyama, H.6
  • 30
    • 84894330173 scopus 로고    scopus 로고
    • Extensive conversion of hepatic biliary epithelial cells to hepatocytes after near total loss of hepatocytes in zebrafish
    • Choi TY, Ninov N, Stainier DY, Shin D. Extensive conversion of hepatic biliary epithelial cells to hepatocytes after near total loss of hepatocytes in zebrafish. Gastroenterology 2014;146:776-788.
    • (2014) Gastroenterology , vol.146 , pp. 776-788
    • Choi, T.Y.1    Ninov, N.2    Stainier, D.Y.3    Shin, D.4
  • 31
    • 84938743495 scopus 로고    scopus 로고
    • Hepatic progenitor cells of biliary origin with liver repopulation capacity
    • Lu WY, Bird TG, Boulter L, Tsuchiya A, Cole AM, Hay T, et al. Hepatic progenitor cells of biliary origin with liver repopulation capacity. Nat Cell Biol 2015;17:971-983.
    • (2015) Nat Cell Biol , vol.17 , pp. 971-983
    • Lu, W.Y.1    Bird, T.G.2    Boulter, L.3    Tsuchiya, A.4    Cole, A.M.5    Hay, T.6
  • 32
    • 84929605817 scopus 로고    scopus 로고
    • Adaptive remodeling of the biliary architecture underlies liver homeostasis
    • Kaneko K, Kamimoto K, Miyajima A, Itoh T. Adaptive remodeling of the biliary architecture underlies liver homeostasis. Hepatology 2015;61:2056-2066.
    • (2015) Hepatology , vol.61 , pp. 2056-2066
    • Kaneko, K.1    Kamimoto, K.2    Miyajima, A.3    Itoh, T.4
  • 33
    • 84892753370 scopus 로고    scopus 로고
    • Links between hepatic fibrosis, ductular reaction, and progenitor cell expansion
    • Williams MJ, Clouston AD, Forbes SJ. Links between hepatic fibrosis, ductular reaction, and progenitor cell expansion. Gastroenterology 2014;146:349-356.
    • (2014) Gastroenterology , vol.146 , pp. 349-356
    • Williams, M.J.1    Clouston, A.D.2    Forbes, S.J.3
  • 34
    • 84867723466 scopus 로고    scopus 로고
    • Hepatic progenitor cells activation, fibrosis and adipokines production in pediatric nonalcoholic fatty liver disease
    • Nobili V, Carpino G, Alisi A, Franchitto A, Alpini G, De Vito R, et al. Hepatic progenitor cells activation, fibrosis and adipokines production in pediatric nonalcoholic fatty liver disease. Hepatology 2012;56:2142-2153.
    • (2012) Hepatology , vol.56 , pp. 2142-2153
    • Nobili, V.1    Carpino, G.2    Alisi, A.3    Franchitto, A.4    Alpini, G.5    De Vito, R.6
  • 35
    • 77149158796 scopus 로고    scopus 로고
    • Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling
    • Spee B, Carpino G, Schotanus BA, Katoonizadeh A, Vander Borght S, Gaudio E, et al. Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling. Gut 2010;59:247-257.
    • (2010) Gut , vol.59 , pp. 247-257
    • Spee, B.1    Carpino, G.2    Schotanus, B.A.3    Katoonizadeh, A.4    Vander Borght, S.5    Gaudio, E.6
  • 36
    • 79952230767 scopus 로고    scopus 로고
    • Epithelial cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans
    • Yoon SM, Gerasimidou D, Kuwahara R, Hytiroglou P, Yoo JE, Park YN, et al. Epithelial cell adhesion molecule (EpCAM) marks hepatocytes newly derived from stem/progenitor cells in humans. Hepatology 2011;53:964-973.
    • (2011) Hepatology , vol.53 , pp. 964-973
    • Yoon, S.M.1    Gerasimidou, D.2    Kuwahara, R.3    Hytiroglou, P.4    Yoo, J.E.5    Park, Y.N.6
  • 37
    • 84928205579 scopus 로고    scopus 로고
    • Hepatocyte buds derived from progenitor cells repopulate regions of parenchymal extinction in human cirrhosis
    • Stueck AE, Wanless IR. Hepatocyte buds derived from progenitor cells repopulate regions of parenchymal extinction in human cirrhosis. Hepatology 2015;61:1696-1707.
    • (2015) Hepatology , vol.61 , pp. 1696-1707
    • Stueck, A.E.1    Wanless, I.R.2
  • 39
    • 4444320484 scopus 로고    scopus 로고
    • Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages
    • Seaberg RM, Smukler SR, Kieffer TJ, Enikolopov G, Asghar Z, Wheeler MB, et al. Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages. Nat Biotechnol 2004;22:1115-1124.
    • (2004) Nat Biotechnol , vol.22 , pp. 1115-1124
    • Seaberg, R.M.1    Smukler, S.R.2    Kieffer, T.J.3    Enikolopov, G.4    Asghar, Z.5    Wheeler, M.B.6
  • 40
    • 84884590283 scopus 로고    scopus 로고
    • Making beta cells from adult cells within the pancreas
    • Lysy PA, Weir GC, Bonner-Weir S. Making beta cells from adult cells within the pancreas. Curr Diab Rep 2013;13:695-703.
    • (2013) Curr Diab Rep , vol.13 , pp. 695-703
    • Lysy, P.A.1    Weir, G.C.2    Bonner-Weir, S.3
  • 41
    • 34147190365 scopus 로고    scopus 로고
    • Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration
    • Desai BM, Oliver-Krasinski J, De Leon DD, Farzad C, Hong N, Leach SD, et al. Preexisting pancreatic acinar cells contribute to acinar cell, but not islet beta cell, regeneration. J Clin Invest 2007;117:971-977.
    • (2007) J Clin Invest , vol.117 , pp. 971-977
    • Desai, B.M.1    Oliver-Krasinski, J.2    De Leon, D.D.3    Farzad, C.4    Hong, N.5    Leach, S.D.6
  • 42
    • 2342510386 scopus 로고    scopus 로고
    • Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation
    • Dor Y, Brown J, Martinez OI, Melton DA. Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation. Nature 2004;429:41-46.
    • (2004) Nature , vol.429 , pp. 41-46
    • Dor, Y.1    Brown, J.2    Martinez, O.I.3    Melton, D.A.4
  • 43
    • 44749088201 scopus 로고    scopus 로고
    • Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans
    • Meier JJ, Butler AE, Saisho Y, Monchamp T, Galasso R, Bhushan A, et al. Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans. Diabetes 2008;57:1584-1594.
    • (2008) Diabetes , vol.57 , pp. 1584-1594
    • Meier, J.J.1    Butler, A.E.2    Saisho, Y.3    Monchamp, T.4    Galasso, R.5    Bhushan, A.6
  • 44
    • 58149378342 scopus 로고    scopus 로고
    • Carbonic anhydrase II–positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth
    • Inada A, Nienaber C, Katsuta H, Fujitani Y, Levine J, Morita R, et al. Carbonic anhydrase II–positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci USA 2008;105:19915-19919.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19915-19919
    • Inada, A.1    Nienaber, C.2    Katsuta, H.3    Fujitani, Y.4    Levine, J.5    Morita, R.6
  • 45
    • 38749108893 scopus 로고    scopus 로고
    • Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas
    • Xu X, D'Hoker J, Stange G, Bonne S, De Leu N, Xiao X, et al. Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 2008;132:197-207.
    • (2008) Cell , vol.132 , pp. 197-207
    • Xu, X.1    D'Hoker, J.2    Stange, G.3    Bonne, S.4    De Leu, N.5    Xiao, X.6
  • 46
    • 84923365135 scopus 로고    scopus 로고
    • Impact of Sox9 dosage and Hes1-mediated Notch signaling in controlling the plasticity of adult pancreatic duct cells in mice
    • Hosokawa S, Furuyama K, Horiguchi M, Aoyama Y, Tsuboi K, Sakikubo M, et al. Impact of Sox9 dosage and Hes1-mediated Notch signaling in controlling the plasticity of adult pancreatic duct cells in mice. Sci Rep 2015;5:8518.
    • (2015) Sci Rep , vol.5 , pp. 8518
    • Hosokawa, S.1    Furuyama, K.2    Horiguchi, M.3    Aoyama, Y.4    Tsuboi, K.5    Sakikubo, M.6
  • 47
    • 77956004353 scopus 로고    scopus 로고
    • Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats
    • Li WC, Rukstalis JM, Nishimura W, Tchipashvili V, Habener JF, Sharma A, et al. Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats. J Cell Sci 2010;123:2792-2802.
    • (2010) J Cell Sci , vol.123 , pp. 2792-2802
    • Li, W.C.1    Rukstalis, J.M.2    Nishimura, W.3    Tchipashvili, V.4    Habener, J.F.5    Sharma, A.6
  • 48
    • 18744394636 scopus 로고    scopus 로고
    • Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB rats
    • Wang GS, Rosenberg L, Scott FW. Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB rats. Lab Invest 2005;85:675-688.
    • (2005) Lab Invest , vol.85 , pp. 675-688
    • Wang, G.S.1    Rosenberg, L.2    Scott, F.W.3
  • 49
    • 77249086130 scopus 로고    scopus 로고
    • Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia
    • Strobel O, Rosow DE, Rakhlin EY, Lauwers GY, Trainor AG, Alsina J, et al. Pancreatic duct glands are distinct ductal compartments that react to chronic injury and mediate Shh-induced metaplasia. Gastroenterology 2010;138:1166-1177.
    • (2010) Gastroenterology , vol.138 , pp. 1166-1177
    • Strobel, O.1    Rosow, D.E.2    Rakhlin, E.Y.3    Lauwers, G.Y.4    Trainor, A.G.5    Alsina, J.6
  • 51
    • 84943328503 scopus 로고    scopus 로고
    • Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells
    • Oikawa T, Wauthier E, Dinh T, Selitsky S, Reyna-Neyra A, Carpino G, et al. Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells. Nat Commun 2015;6:8070.
    • (2015) Nat Commun , vol.6 , pp. 8070
    • Oikawa, T.1    Wauthier, E.2    Dinh, T.3    Selitsky, S.4    Reyna-Neyra, A.5    Carpino, G.6
  • 52
    • 84888250929 scopus 로고    scopus 로고
    • Pathogenesis, diagnosis, and management of cholangiocarcinoma
    • Rizvi S, Gores GJ. Pathogenesis, diagnosis, and management of cholangiocarcinoma. Gastroenterology 2013;145:1215-1229.
    • (2013) Gastroenterology , vol.145 , pp. 1215-1229
    • Rizvi, S.1    Gores, G.J.2
  • 53
    • 84964313384 scopus 로고    scopus 로고
    • Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis
    • Cardinale V, Carpino G, Gentile R, Napoletano C, Rahimi H, Franchitto A, et al. Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis. BMC Gastroenterol 2014;14:204.
    • (2014) BMC Gastroenterol , vol.14 , pp. 204
    • Cardinale, V.1    Carpino, G.2    Gentile, R.3    Napoletano, C.4    Rahimi, H.5    Franchitto, A.6


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