-
1
-
-
84926348812
-
Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: Differential involvement of immunerelated gene loci
-
Andreassen,O. et al. (2015) Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immunerelated gene loci. Mol. Psychiatry, 20, 207-214.
-
(2015)
Mol. Psychiatry
, vol.20
, pp. 207-214
-
-
Andreassen, O.1
-
2
-
-
84873701087
-
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors
-
Andreassen,O.A. et al. (2013) Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors. Am. J. Hum. Genet., 92, 197-209.
-
(2013)
Am. J. Hum. Genet.
, vol.92
, pp. 197-209
-
-
Andreassen, O.A.1
-
3
-
-
84912117315
-
GPA: A statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation
-
Chung,D. et al. (2014) GPA: a statistical approach to prioritizing GWAS results by integrating pleiotropy and annotation. PLoS Genet., 10, e1004787.
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004787
-
-
Chung, D.1
-
4
-
-
84890546613
-
Systems genetics approaches to understand complex traits
-
Civelek,M. and Lusis,A.J. (2014) Systems genetics approaches to understand complex traits. Nat. Rev. Genet., 15, 34-48.
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 34-48
-
-
Civelek, M.1
Lusis, A.J.2
-
5
-
-
84883465830
-
Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs
-
Cross-Disorder Group of the Psychiatric Genomics Consortium
-
Cross-Disorder Group of the Psychiatric Genomics Consortium (2013a) Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat. Genet., 45, 984-994.
-
(2013)
Nat. Genet.
, vol.45
, pp. 984-994
-
-
-
6
-
-
84876296688
-
Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
-
Cross-Disorder Group of the Psychiatric Genomics Consortium
-
Cross-Disorder Group of the Psychiatric Genomics Consortium (2013b) Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet, 381, 1371-1379.
-
(2013)
Lancet
, vol.381
, pp. 1371-1379
-
-
-
7
-
-
0344483873
-
MRI analysis of the cerebellum in bipolar disorder: A pilot study
-
DelBello,M.P. et al. (1999) MRI analysis of the cerebellum in bipolar disorder: a pilot study. Neuropsychopharmacology, 21, 63-68.
-
(1999)
Neuropsychopharmacology
, vol.21
, pp. 63-68
-
-
DelBello, M.P.1
-
8
-
-
84929731128
-
-
Cambridge University Press,Cambridge, UK
-
Efron,B. (2010). Large-Scale Inference: Empirical Bayes Methods for Estimation, Testing, and Prediction, volume 1. Cambridge University Press, Cambridge, UK.
-
(2010)
Large-Scale Inference: Empirical Bayes Methods for Estimation, Testing, and Prediction
, vol.1
-
-
Efron, B.1
-
9
-
-
47749152434
-
Microarrays, empirical Bayes and the two-groups model
-
Efron,B. et al. (2008) Microarrays, empirical Bayes and the two-groups model. Stat. Sci., 23, 1-22.
-
(2008)
Stat. Sci.
, vol.23
, pp. 1-22
-
-
Efron, B.1
-
10
-
-
84941053261
-
GRASP v2.0: An update on the Genome-Wide Repository of Associations between SNPs and phenotypes
-
Eicher,J.D. et al. (2015) GRASP v2.0: an update on the Genome-Wide Repository of Associations between SNPs and phenotypes. Nucleic Acids Res., 43, D799-D804.
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. D799-D804
-
-
Eicher, J.D.1
-
11
-
-
53849089038
-
High dimensional classification using features annealed independence rules
-
Fan,J. and Fan,Y. (2008) High dimensional classification using features annealed independence rules. Ann. Stat., 36, 2605.
-
(2008)
Ann. Stat.
, vol.36
, pp. 2605
-
-
Fan, J.1
Fan, Y.2
-
12
-
-
84878476783
-
A statistical framework for joint EQTL analysis in multiple tissues
-
Flutre,T. et al. (2013) A statistical framework for joint EQTL analysis in multiple tissues. PLoS Genet., 9, e1003486.
-
(2013)
PLoS Genet.
, vol.9
, pp. e1003486
-
-
Flutre, T.1
-
13
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke,A. et al. (2010) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat. Genet., 42, 1118-1125.
-
(2010)
Nat. Genet.
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
-
14
-
-
78049347495
-
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
-
Genetic Analysis of Psoriasis Consortium and the Wellcome Trust Case Control Consortium
-
Genetic Analysis of Psoriasis Consortium and the Wellcome Trust Case Control Consortium (2010) A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat. Genet., 42, 985-990.
-
(2010)
Nat. Genet.
, vol.42
, pp. 985-990
-
-
-
15
-
-
84923634571
-
Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing
-
Gutierrez-Arcelus,M. et al. (2015) Tissue-specific effects of genetic and epigenetic variation on gene regulation and splicing. PLoS Genet, 11, e1004958.
-
(2015)
PLoS Genet
, vol.11
, pp. e1004958
-
-
Gutierrez-Arcelus, M.1
-
16
-
-
53949099624
-
The role of the cerebellum in the pathophysiology and treatment of neuropsychiatric disorders: A review
-
Hoppenbrouwers,S.S. et al. (2008) The role of the cerebellum in the pathophysiology and treatment of neuropsychiatric disorders: a review. Brain Res. Rev., 59, 185-200.
-
(2008)
Brain Res. Rev.
, vol.59
, pp. 185-200
-
-
Hoppenbrouwers, S.S.1
-
17
-
-
84938551261
-
Brain abnormalities in bipolar disorder detected by quantitative t1q mapping
-
Johnson,C. et al. (2015) Brain abnormalities in bipolar disorder detected by quantitative t1q mapping. Mol. Psychiatry, 20, 201-206.
-
(2015)
Mol. Psychiatry
, vol.20
, pp. 201-206
-
-
Johnson, C.1
-
18
-
-
84927739557
-
JEPEG: A summary statistics based tool for gene-level joint testing of functional variants
-
Lee,D. et al. (2015) JEPEG: a summary statistics based tool for gene-level joint testing of functional variants. Bioinformatics, 31, 1176-1182.
-
(2015)
Bioinformatics
, vol.31
, pp. 1176-1182
-
-
Lee, D.1
-
19
-
-
79952467494
-
GATES: A rapid and powerful gene-based association test using extended SIMES procedure
-
Li,M.X. et al. (2011) GATES: a rapid and powerful gene-based association test using extended SIMES procedure. Am. J. Hum. Genet., 88, 283-293.
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 283-293
-
-
Li, M.X.1
-
20
-
-
77955064853
-
A versatile gene-based test for genome-wide association studies
-
Liu,J.Z. et al. (2010) A versatile gene-based test for genome-wide association studies. Am. J. Hum. Genet., 87, 139-145.
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 139-145
-
-
Liu, J.Z.1
-
21
-
-
46049110099
-
Tiger: A database for tissue-specific gene expression and regulation
-
Liu,X. et al. (2008) Tiger: a database for tissue-specific gene expression and regulation. BMC Bioinformatics, 9, 271.
-
(2008)
BMC Bioinformatics
, vol.9
, pp. 271
-
-
Liu, X.1
-
22
-
-
84878682420
-
The genotype-tissue expression (GTEx) project
-
Lonsdale,J. et al. (2013) The genotype-tissue expression (GTEx) project. Nat. Genet., 45, 580-585.
-
(2013)
Nat. Genet.
, vol.45
, pp. 580-585
-
-
Lonsdale, J.1
-
23
-
-
44349142294
-
Common variants near mc4r are associated with fat mass, weight and risk of obesity
-
Loos,R.J. et al. (2008) Common variants near mc4r are associated with fat mass, weight and risk of obesity. Nat. Genet., 40, 768-775.
-
(2008)
Nat. Genet.
, vol.40
, pp. 768-775
-
-
Loos, R.J.1
-
24
-
-
33645454744
-
Schizophrenia and bipolar disorder: Differences and overlaps
-
Maier,W. et al. (2006) Schizophrenia and bipolar disorder: differences and overlaps. Curr. Opin. Psychiatry, 19, 165-170.
-
(2006)
Curr. Opin. Psychiatry
, vol.19
, pp. 165-170
-
-
Maier, W.1
-
25
-
-
23344435674
-
MRI analysis of cerebellar vermal abnormalities in bipolar disorder
-
Mills,N.P. et al. (2005) MRI analysis of cerebellar vermal abnormalities in bipolar disorder. Am. J. Psychiatry, 162, 1530-1532.
-
(2005)
Am. J. Psychiatry
, vol.162
, pp. 1530-1532
-
-
Mills, N.P.1
-
26
-
-
84922634287
-
Vegas2: Software for more flexible genebased testing
-
Mishra,A. and Macgregor,S. (2015) Vegas2: software for more flexible genebased testing. Twin Res. Hum. Genet., 18, 86-91.
-
(2015)
Twin Res. Hum. Genet.
, vol.18
, pp. 86-91
-
-
Mishra, A.1
Macgregor, S.2
-
27
-
-
84876933612
-
Acquisition of normal tissues for the GTEx program
-
Moore,H.M. (2013) Acquisition of normal tissues for the GTEx program. Biopreserv. Biobank., 11, 75-76.
-
(2013)
Biopreserv. Biobank.
, vol.11
, pp. 75-76
-
-
Moore, H.M.1
-
28
-
-
4143134235
-
The future of association studies: Genebased analysis and replication
-
Neale,B.M. and Sham,P.C. (2004) The future of association studies: genebased analysis and replication. Am. J. Hum. Genet., 75, 353-362.
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 353-362
-
-
Neale, B.M.1
Sham, P.C.2
-
29
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
Purcell,S.M. et al. (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature, 460, 748-752.
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
Purcell, S.M.1
-
30
-
-
84925031191
-
Methods of integrating data to uncover genotypephenotype interactions
-
Ritchie,M.D. et al. (2015) Methods of integrating data to uncover genotypephenotype interactions. Nat. Rev. Genet., 16, 85-97.
-
(2015)
Nat. Rev. Genet.
, vol.16
, pp. 85-97
-
-
Ritchie, M.D.1
-
31
-
-
84904804929
-
Biological insights from 108 schizophrenia-associated genetic loci
-
Schizophrenia Working Group of the Psychiatric Genomics Consortium
-
Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014) Biological insights from 108 schizophrenia-associated genetic loci. Nature, 511, 421-427.
-
(2014)
Nature
, vol.511
, pp. 421-427
-
-
-
32
-
-
74849105720
-
Empirical null and false discovery rate inference for exponential families
-
Schwartzman,A. (2008) Empirical null and false discovery rate inference for exponential families. Ann. Appl. Stat., 2, 13321359.
-
(2008)
Ann. Appl. Stat.
, vol.2
, pp. 13321359
-
-
Schwartzman, A.1
-
33
-
-
84866488405
-
Moving toward system genetics through multiple trait analysis in genome-wide association studies
-
Shriner,D. (2012) Moving toward system genetics through multiple trait analysis in genome-wide association studies. Front. Genet., 3, 1.
-
(2012)
Front. Genet.
, vol.3
, pp. 1
-
-
Shriner, D.1
-
34
-
-
84879419343
-
Pleiotropy in complex traits: Challenges and strategies
-
Solovieff,N. et al. (2013) Pleiotropy in complex traits: challenges and strategies. Nat. Rev. Genet., 14, 483-495.
-
(2013)
Nat. Rev. Genet.
, vol.14
, pp. 483-495
-
-
Solovieff, N.1
-
35
-
-
78951491095
-
One hundred years of pleiotropy: A retrospective
-
Stearns,F.W. (2010) One hundred years of pleiotropy: a retrospective. Genetics, 186, 767-773.
-
(2010)
Genetics
, vol.186
, pp. 767-773
-
-
Stearns, F.W.1
-
36
-
-
39749118602
-
Multiple loci identified in a genome-wide association study of prostate cancer
-
Thomas,G. et al. (2008) Multiple loci identified in a genome-wide association study of prostate cancer. Nat. Genet., 40, 310-315.
-
(2008)
Nat. Genet.
, vol.40
, pp. 310-315
-
-
Thomas, G.1
-
38
-
-
34547498546
-
A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24
-
Tomlinson,I. et al. (2007) A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat. Genet., 39, 984-988.
-
(2007)
21. Nat. Genet.
, vol.39
, pp. 984-988
-
-
Tomlinson, I.1
-
39
-
-
84922282349
-
Cross-tissue and tissue-specific eQTLs: Partitioning the heritability of a complex trait
-
Torres,J.M. et al. (2014) Cross-tissue and tissue-specific eQTLs: partitioning the heritability of a complex trait. Am. J. Hum. Genet., 95, 521-534.
-
(2014)
Am. J. Hum. Genet.
, vol.95
, pp. 521-534
-
-
Torres, J.M.1
-
41
-
-
84862909349
-
Five years of GWAS discovery
-
Visscher,P.M. et al. (2012) Five years of GWAS discovery. Am. J. Hum. Genet., 90, 7-24.
-
(2012)
Am. J. Hum. Genet.
, vol.90
, pp. 7-24
-
-
Visscher, P.M.1
-
42
-
-
43449101561
-
Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia
-
Walker,E. et al. (2008) Stress and the hypothalamic pituitary adrenal axis in the developmental course of schizophrenia.Annu. Rev. Clin.Psychol., 4, 189-216.
-
(2008)
Annu. Rev. Clin.Psychol.
, vol.4
, pp. 189-216
-
-
Walker, E.1
-
43
-
-
84946489646
-
Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS
-
Wang,Q. et al. (2015) Pervasive pleiotropy between psychiatric disorders and immune disorders revealed by integrative analysis of multiple GWAS. Hum. Genet., 134, 1195-1209.
-
(2015)
Hum. Genet.
, vol.134
, pp. 1195-1209
-
-
Wang, Q.1
-
44
-
-
84891790401
-
The NHGRI GWAS catalog, a curated resource of SNP-trait associations
-
Welter,D. et al. (2014) The NHGRI GWAS catalog, a curated resource of SNP-trait associations. Nucleic Acids Res., 42, D1001-D1006.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. D1001-D1006
-
-
Welter, D.1
-
45
-
-
80054768348
-
Penalized classification using fisher's linear discriminant
-
Witten,D.M. and Tibshirani,R. (2011) Penalized classification using fisher's linear discriminant. J. R. Stat. Soc. B, 73, 753-772.
-
(2011)
J. R. Stat. Soc. B
, vol.73
, pp. 753-772
-
-
Witten, D.M.1
Tibshirani, R.2
-
46
-
-
84940106751
-
Implications of pleiotropy: Challenges and opportunities for mining big data in biomedicine
-
Yang,C. et al. (2015) Implications of pleiotropy: challenges and opportunities for mining big data in biomedicine. Front. Genet., 6, 229.
-
(2015)
Front. Genet.
, vol.6
, pp. 229
-
-
Yang, C.1
-
47
-
-
82255175589
-
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11
-
Yue,W.H. et al. (2011) Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat. Genet., 43, 1228-1231.
-
(2011)
2. Nat. Genet.
, vol.43
, pp. 1228-1231
-
-
Yue, W.H.1
-
48
-
-
84904959814
-
Covariate-modulated local false discovery rate for genome-wide association studies
-
Zablocki,R.W. et al. (2014) Covariate-modulated local false discovery rate for genome-wide association studies. Bioinformatics, 30, 2098-2104.
-
(2014)
Bioinformatics
, vol.30
, pp. 2098-2104
-
-
Zablocki, R.W.1
-
49
-
-
84897954264
-
Efficient multivariate linear mixed model algorithms for genome-wide association studies
-
Zhou,X. and Stephens,M. (2014) Efficient multivariate linear mixed model algorithms for genome-wide association studies. Nat. Methods, 11, 407-409.
-
(2014)
Nat. Methods
, vol.11
, pp. 407-409
-
-
Zhou, X.1
Stephens, M.2
|