Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

Nature Communications

Volumn 7, Issue , 2016, Pages

  Benraiss, Abdellatif ^a   Wang, Su ^a   Herrlinger, Stephanie ^a   Li, Xiaojie ^a   Chandler Militello, Devin ^a   Mauceri, Joseph ^a   Burm, Hayley B ^a   Toner, Michael ^a   Osipovitch, Mikhail ^b   Jim Xu, Qiwu ^a   Ding, Fengfei ^a   Wang, Fushun ^a   Kang, Ning ^a   Kang, Jian ^c   Curtin, Paul C ^d   Brunner, Daniela ^d   Windrem, Martha S ^a   Munoz Sanjuan, Ignacio ^e   Nedergaard, Maiken ^a,b   Goldman, Steven A ^a,b,f  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c NEW YORK MEDICAL COLLEGE   (United States)

^d PSYCHOGENICS INC   (United States)

^e CHDI MANAGEMENT CHDI FOUNDATION   (United States)

^f Rigshospitalet   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; POTASSIUM; HTT PROTEIN, MOUSE; HYALURONIC ACID BINDING PROTEIN;

CELLS AND CELL COMPONENTS; HOMEOSTASIS; MUTATION; NERVOUS SYSTEM DISORDER; PATHOLOGY; PHENOTYPE; POTASSIUM; RODENT; SURVIVAL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAG REPEAT; CELL ISOLATION; CELL SELECTION; CHIMERA; CONTROLLED STUDY; CYTOPATHOLOGY; DISEASE COURSE; ENGRAFTMENT; EXON; FEMALE; FETAL BRAIN; FETUS; GESTATIONAL AGE; GLIA CELL; HOMEOSTASIS; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; HUNTINGTON CHOREA; IMMUNOCYTOCHEMISTRY; MACROGLIA; MALE; MEMBRANE STEADY POTENTIAL; MENTAL DETERIORATION; MOTOR PERFORMANCE; MOUSE; NEUROPATHOLOGY; NEWBORN; NONHUMAN; NORMAL HUMAN; OLIGODENDROGLIA; PHENOTYPE; POTASSIUM HOMEOSTASIS; POTASSIUM METABOLISM; SURVIVAL; ANIMAL; ANIMAL BEHAVIOR; COGNITION; DISEASE EXACERBATION; GENETIC CROSS; GLIA; METABOLISM; MOTOR ACTIVITY; NEOSTRIATUM; NERVE CELL; PATHOLOGY; STEM CELL TRANSPLANTATION; SURVIVAL ANALYSIS;

MUS;

ANIMALS; BEHAVIOR, ANIMAL; CHIMERA; COGNITION; CROSSES, GENETIC; DISEASE PROGRESSION; FEMALE; HUMAN EMBRYONIC STEM CELLS; HUMANS; HUNTINGTIN PROTEIN; HUNTINGTON DISEASE; HYALURONAN RECEPTORS; MALE; MICE; MOTOR ACTIVITY; NEOSTRIATUM; NEUROGLIA; NEURONS; PHENOTYPE; STEM CELL TRANSPLANTATION; SURVIVAL ANALYSIS;

EID: 84976358857     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11758     Document Type: Article

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