Formaldehyde induces toxicity in mouse bone marrow and hematopoietic stem/progenitor cells and enhances benzene-induced adverse effects

Archives of Toxicology

Volumn 91, Issue 2, 2017, Pages 921-933

  Wei, Chenxi ^a,c   Wen, Huaxiao ^a   Yuan, Langyue ^a   McHale, Cliona M ^b   Li, Hui ^a   Wang, Kun ^a,d   Yuan, Junlin ^a   Yang, Xu ^a   Zhang, Luoping ^b  

^a CENTRAL CHINA NORMAL UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HUNAN NORMAL UNIVERSITY   (China)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Benzene; Bone marrow; Formaldehyde; Hematotoxicity; Myeloid progenitor

Indexed keywords

BENZENE; CASPASE 3; FORMALDEHYDE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEMOPOIETIC GROWTH FACTOR; INTERLEUKIN 3; REACTIVE OXYGEN METABOLITE; CASP3 PROTEIN, MOUSE; GROWTH FACTOR RECEPTOR; SIGNAL PEPTIDE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BLOOD CELL COUNT; BLOOD TOXICITY; BONE MARROW TOXICITY; COLONY FORMING UNIT; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEMATOPOIETIC STEM CELL; IN VIVO STUDY; LEUKEMIA; MALE; MOUSE; MYELOID PROGENITOR CELL; NONHUMAN; OCCUPATIONAL EXPOSURE; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPLEEN CELL; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BONE MARROW CELL; DRUG EFFECTS; METABOLISM; PATHOLOGY; PROCEDURES; SPLEEN; TOXICITY TESTING;

ANIMALS; APOPTOSIS; BENZENE; BLOOD CELL COUNT; BONE MARROW CELLS; CASPASE 3; FORMALDEHYDE; HEMATOPOIETIC STEM CELLS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE, INBRED BALB C; REACTIVE OXYGEN SPECIES; RECEPTORS, GROWTH FACTOR; SPLEEN; TOXICITY TESTS;

EID: 84976311672     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-016-1760-5     Document Type: Article

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