Formaldehyde induces lung inflammation by an oxidant and antioxidant enzymes mediated mechanism in the lung tissue

Toxicology Letters

Volumn 207, Issue 3, 2011, Pages 278-285

  Lino dos Santos Franco, Adriana ^a   Correa Costa, Matheus ^a   Dos Santos Durão, Ana Carolina Cardoso ^a   Ligeiro de Oliveira, Ana Paula ^a   Breithaupt Faloppa, Ana Cristina ^a   Bertoni, Jônatas de Almeida ^a   Oliveira Filho, Ricardo Martins ^a   Câmara, Niels Olsen Saraiva ^a   Marcourakis, Tânia ^a   Tavares de Lima, Wothan ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Formaldehyde; Inflammatory mediators; Lung inflammation; Oxidants and anti oxidant enzymes; Reactive oxygen and nitrogen species

Indexed keywords

APOCYNIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; FORMALDEHYDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; HYDROGEN PEROXIDE; INDOMETACIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDOREDUCTASE; OXYGENASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; GENE ACTIVITY; GENE EXPRESSION; INTERFERON PRODUCTION; MALE; NONHUMAN; OXIDATIVE STRESS; PNEUMONIA; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM;

ANIMALS; CATALASE; FORMALDEHYDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; GLUTATHIONE TRANSFERASE; INFLAMMATION; INHALATION EXPOSURE; LUNG; MALE; NITRIC OXIDE SYNTHASE; OXIDATION-REDUCTION; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE;

RATTUS NORVEGICUS;

EID: 80054116229     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.09.026     Document Type: Article

References (29)

1. Aebi H. Catalase in vitro. Methods Enzymol. 1984, 105:121-126.
2. Baba K., Yagi T., Niwa S., Sakakibara A., Hattori T., Koishikawa I., Yoshida K., Yashi T. Measurement of formaldehyde-specific IgE antibodies in adult asthmatics. Arerugi 2000, 49:404-411.
3. Carlberg I., Mannervik B. Purification and characterization of the flavoenzyme glutathione reductase from rat liver. J. Biol. Chem. 1975, 250(14):5475-5480.
4. Carlson R.M., Smith M.C., Nedorost S.T. Diagnosis and treatment of dermatitis due to formaldehyde resins in clothing. Dermatitis 2004, 15:169-175.
5. Casset A., Marchand C., Purohit A., Le Calvé S., Donnay C., Meyer P., Pauli G., de Blay F. Inhalation de faibles doses de formaldéhyde gazeux: effet sur la réponse bronchique chez des astmatiques sensibilisés aux acariens. Rev. Fr. Allergol. Immunol. Clin. 2005, 45:291.
6. Cross A.R., Jones O.T. Enzymic mechanisms of superoxide production. Biochim. Biophys. Acta 1991, 1057(3):281-298.
7. De Lima W.T., Sirois P., Jancar S. Immune-complex alveolitis in the rat: evidence for platelet activating factor and leukotrienes as mediators of the vascular lesions. Eur. J. Pharmacol. 1992, 213:63-70.
8. Delfino R.J. Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research. Environ. Health Perspect. 2002, 110:573-589.
9. Doreswamy K., Shrilatha B., Rajeshkumar T., Muralidhara Nickel-induced oxidative stress in testes of mice: evidence of DNA damage and genotoxic effects. J. Androl. 2004, 25:996-1003.
10. Flohé L., Günzler W.A. Assays of glutathione peroxidase. Methods Enzymol. 1984, 105:114-121.
11. Flohé L., Otting F. Superoxide dismutase assays. Methods Enzymol. 1984, 105:93-104.
12. Fló-Neyret C., Lorenzi-Filho G., Macchione M., Garcia M.L.B., Saldiva P.H.N. Effects of formaldehyde on the frog's mucociliary epithelium as a surrogate to evaluate air pollution effects on the respiratory epithelium. Braz. J. Med. Biol. Res. 2001, 34:639-643.
13. Fujii J., Iuchi Y., Matsuki S., Ishii T. Cooperative function of antioxidant and redox systems against oxidative stress in male reproductive tissues. Asian J. Androl. 2003, 5:231-242.
14. Gülec M., Songur A., Sahin S., Ozen O.A., Sarsilmaz M., Akyol O. Antioxidant enzyme activities and lipid peroxidation products in heart tissue of subacute and subchronic formaldehyde-exposed rats: a preliminary study. Toxicol. Ind. Health 2006, 22(3):117-124.
15. Gurel A., Coskun O., Armutcu F., Kanter M., Ozen O.A. Vitamin E against oxidative damage caused by formaldehyde in frontal cortex and hippocampus: biochemical and histological studies. J. Chem. Neuroanat. 2005, 29(3):173-178.
16. Habig W.H., Pabst M.J., Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249(22):7130-7139.
17. Halliwell B., Gutteridge J.M. Iron toxicity and oxygen radicals. Baillieres Clin. Haematol. 1989, 2(2):195-256.
18. Heck H.D., Casanova M., Starr T.B. Formaldehyde toxicity-new understanding. Crit. Rev. Toxicol. 1990, 20(6):397-426.
19. Kaminsky D.A., van der Vliet A., Janssen-Heininger Y.J. Reactive nitrogen species in refractory asthma: markers or players?. Allergy Clin. Immunol. 2008, 121(2):338-340.
20. Krakowiak A., Górski P., Pazdrak K., Ruta U. Airway response to formaldehyde inhalation in asthmatic subjects with suspected respiratory formaldehyde sensitization. Am. J. Ind. Med. 1998, 33:274-281.
21. Lino dos Santos Franco A., Damazo A.S., Beraldo de Souza H.R., Domingos H.V., Oliveira-Filho R.M., Oliani S.M., Costa S.K., Tavares de Lima W. Pulmonary neutrophil recruitment and bronchial reactivity in formaldehyde-exposed rats are modulated by mast cells and differentially by neuropeptides and nitric oxide. Toxicol. Appl. Pharmacol. 2006, 214:35-42.
22. Lino-dos-Santos-Franco A., Domingos H.V., Damazo A.S., Breithaupt-Faloppa A., Ligeiro de Oliveira A.P., Costa S.K.P., Oliani S.M., Oliveira-Filho R.M., Vargaftig B.B., Tavares de Lima W. Reduced allergic lung inflammation in rats following formaldehyde exposure: long-term effects on multiple effector systems. Toxicology 2009, 256(3):157-163.
23. Lino-Dos-Santos-Franco A., Domingos H.V., Oliveira A.P., Breithaupt-Faloppa A.C., Peron J.P., Bolonheis S., Muscará M.N., Oliveira-Filho R.M., Vargaftig B.B., Tavares-de-Lima W. Differential effects of formaldehyde exposure on the cell influx and vascular permeability in a rat model of allergic lung inflammation. Toxicol. Lett. 2010, 197(3):211-218.
24. McCord J.M., Fridovich I. The utility of superoxide dismutase in studying free radical reactions. I. Radicals generated by the interaction of sulfite, dimethyl sulfoxide, and oxygen. J. Biol. Chem. 1969, 244:6056L 6063.
25. Mendell M.J., Heath G.A. Do indoor pollutants and thermal conditions in schools influence student performance? A critical review of the literature. Indoor Air 2005, 15:27-52.
26. Pick E., Miziel D. Rapid microassays for the measurement of superoxide and hydrogen peroxide production by macrophages in culture using automatic immunoassay reader. J. Immunol. Methods 1981, 46:221-226.
27. Proust B., Nahori M.A., Ruffie C., Lefort J., Vargaftig B.B. Persistence of bronchopulmonary hyper-reactivity and eosinophilic lung inflammation after anti-IL-5 or -IL-13 treatment in allergic BALB/c and IL-4Ralpha knockout mice. Clin. Exp. Allergy 2003, 33(1):119-131.
28. Reynaert N.L., Ckless K., Wouters E.F., van der Vliet A., Janssen-Heininger Y.M. Nitric oxide and redox signaling in airway inflammation. Antioxid. Redox Signal. 2005, 7:129L 143.
29. Wolin M.S. Interactions of oxidants with vascular signaling systems. Arterioscler. Thromb. Vasc. Biol. 2000, 20(6):1430-1442.