The future of vascular biology and medicine

Circulation

Volumn 133, Issue 25, 2016, Pages 2603-2609

  Kinlay, Scott ^a,b   Michel, Thomas ^b   Leopold, Jane A ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

biology vessels; gastrointestinal microbiome; hypertension, pulmonary; peripheral arterial disease

Indexed keywords

ANGIOGENESIS; ARTICLE; BLOOD VESSEL; BLOOD VESSEL WALL; CELL CULTURE; CIRCULATION; DIET; DISEASE ASSOCIATION; ENDOCRINE FUNCTION; EXERCISE; HOMEOSTASIS; HOSPITAL SERVICE; HUMAN; MEDICAL RESEARCH; MEDICINE; MICROBIOME; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RISK FACTOR; VASCULAR BIOLOGY; VASCULAR DISEASE; ANIMAL; CARDIOLOGY; DYSBIOSIS; FORECASTING; GASTROINTESTINAL TRACT; GENETICS; HOST PATHOGEN INTERACTION; INTESTINE FLORA; MICROBIOLOGY; PATHOPHYSIOLOGY; PROGNOSIS; TRENDS; VASCULAR DISEASES;

ANIMALS; BIOMEDICAL RESEARCH; BLOOD VESSELS; CARDIOLOGY; DYSBIOSIS; FORECASTING; GASTROINTESTINAL MICROBIOME; GASTROINTESTINAL TRACT; HOST-PATHOGEN INTERACTIONS; HUMANS; PROGNOSIS; RISK FACTORS; VASCULAR DISEASES;

EID: 84975807265     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.116.023513     Document Type: Article

References (48)

1. Furchgott RF, Zawadzki JV, The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980 288 373 376
2. Barre-Sinoussi F, Montagutelli X, Animal models are essential to biological research: issues and perspectives. Future Science OA 2015 1
3. Said HM, Intestinal absorption of water-soluble vitamins in health and disease. Biochem J 2011 437 357 372. doi: 10.1042/BJ20110326
4. Stappenbeck TS, Hooper LV, Gordon JI, Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proc Natl Acad Sci U S A 2002 99 15451 15455. doi: 10.1073/pnas.202604299
5. Bäckhed F, Manchester JK, Semenkovich CF, Gordon JI, Mechanisms underlying the resistance to diet-induced obesity in germ-free mice. Proc Natl Acad Sci U S A 2007 104 979 984. doi: 10.1073/pnas.0605374104
6. Wen L, Ley RE, Volchkov PY, Stranges PB, Avanesyan L, Stonebraker AC, Hu C, Wong FS, Szot GL, Bluestone JA, Gordon JI, Chervonsky AV, Innate immunity and intestinal microbiota in the development of type 1 diabetes. Nature 2008 455 1109 1113. doi: 10.1038/nature07336
7. Human Microbiome Project Consortium Structure, function and diversity of the healthy human microbiome. Nature 2012 486 207 14
8. Ley RE, Turnbaugh PJ, Klein S, Gordon JI, Microbial ecology: human gut microbes associated with obesity. Nature 2006 444 1022 1023. doi: 10.1038/4441022a
9. Cox LM, Blaser MJ, Pathways in microbe-induced obesity. Cell Metab 2013 17 883 894. doi: 10.1016/j.cmet.2013.05.004
10. Yang T, Santisteban MM, Rodriguez V, Li E, Ahmari N, Carvajal JM, Zadeh M, Gong M, Qi Y, Zubcevic J, Sahay B, Pepine CJ, Raizada MK, Mohamadzadeh M, Gut dysbiosis is linked to hypertension. Hypertension 2015 65 1331 1340. doi: 10.1161/HYPERTENSIONAHA.115.05315
11. Tang WH, Hazen SL, The contributory role of gut microbiota in cardiovascular disease. J Clin Invest 2014 124 4204 4211. doi: 10.1172/JCI72331
12. Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, Dugar B, Feldstein AE, Britt EB, Fu X, Chung YM, Wu Y, Schauer P, Smith JD, Allayee H, Tang WH, DiDonato JA, Lusis AJ, Hazen SL, Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 2011 472 57 63. doi: 10.1038/nature09922
13. Gregory JC, Buffa JA, Org E, Wang Z, Levison BS, Zhu W, Wagner MA, Bennett BJ, Li L, DiDonato JA, Lusis AJ, Hazen SL, Transmission of atherosclerosis susceptibility with gut microbial transplantation. J Biol Chem 2015 290 5647 5660. doi: 10.1074/jbc.M114.618249
14. Aboyans V, Criqui MH, Abraham P, Allison MA, Creager MA, Diehm C, Fowkes FG, Hiatt WR, Jönsson B, Lacroix P, Marin B, McDermott MM, Norgren L, Pande RL, Preux PM, Stoffers HE, Treat-Jacobson D, American Heart Association Council on Peripheral Vascular Disease; Council on Epidemiology and Prevention; Council on Clinical Cardiology; Council on Cardiovascular Nursing; Council on Cardiovascular Radiology and Intervention, and Council on Cardiovascular Surgery and Anesthesia Measurement and interpretation of the ankle-brachial index: a scientific statement from the American Heart Association. Circulation 2012 126 2890 2909. doi: 10.1161/CIR.0b013e318276fbcb
15. Hamburg NM, Balady GJ, Exercise rehabilitation in peripheral artery disease: functional impact and mechanisms of benefits. Circulation 2011 123 87 97. doi: 10.1161/CIRCULATIONAHA.109.881888
16. Berger JS, Hiatt WR, Medical therapy in peripheral artery disease. Circulation 2012 126 491 500. doi: 10.1161/CIRCULATIONAHA.111.033886
17. Pande RL, Hiatt WR, Zhang P, Hittel N, Creager MA, A pooled analysis of the durability and predictors of treatment response of cilostazol in patients with intermittent claudication. Vasc Med 2010 15 181 188. doi: 10.1177/1358863X10361545
18. Murphy TP, Cutlip DE, Regensteiner JG, Mohler ER, Cohen DJ, Reynolds MR, Massaro JM, Lewis BA, Cerezo J, Oldenburg NC, Thum CC, Goldberg S, Jaff MR, Steffes MW, Comerota AJ, Ehrman J, Treat-Jacobson D, Walsh ME, Collins T, Badenhop DT, Bronas U, Hirsch AT, CLEVER Study Investigators Supervised exercise versus primary stenting for claudication resulting from aortoiliac peripheral artery disease: six-month outcomes from the Claudication: Exercise Versus Endoluminal Revascularization (CLEVER) study. Circulation 2012 125 130 139. doi: 10.1161/CIRCULATIONAHA.111.075770
19. Erbs S, Höllriegel R, Linke A, Beck EB, Adams V, Gielen S, Möbius-Winkler S, Sandri M, Kränkel N, Hambrecht R, Schuler G, Exercise training in patients with advanced chronic heart failure (NYHA IIIb) promotes restoration of peripheral vasomotor function, induction of endogenous regeneration, and improvement of left ventricular function. Circ Heart Fail 2010 3 486 494. doi: 10.1161/CIRCHEARTFAILURE.109.868992
20. Pahkala K, Heinonen OJ, Simell O, Viikari JS, Rönnemaa T, Niinikoski H, Raitakari OT, Association of physical activity with vascular endothelial function and intima-media thickness. Circulation 2011 124 1956 1963. doi: 10.1161/CIRCULATIONAHA.111.043851
21. Suboc TB, Strath SJ, Dharmashankar K, Coulliard A, Miller N, Wang J, Tanner MJ, Widlansky ME, Relative importance of step count, intensity, and duration on physical activity's impact on vascular structure and function in previously sedentary older adults. J Am Heart Assoc 2014 3 e000702. doi: 10.1161/JAHA.113.000702
22. Vona M, Codeluppi GM, Iannino T, Ferrari E, Bogousslavsky J, von Segesser LK, Effects of different types of exercise training followed by detraining on endothelium-dependent dilation in patients with recent myocardial infarction. Circulation 2009 119 1601 1608. doi: 10.1161/CIRCULATIONAHA.108.821736
23. Higashi Y, Sasaki S, Sasaki N, Nakagawa K, Ueda T, Yoshimizu A, Kurisu S, Matsuura H, Kajiyama G, Oshima T, Daily aerobic exercise improves reactive hyperemia in patients with essential hypertension. Hypertension 1999 33 pt 2 591 597
24. Lewis TV, Dart AM, Chin-Dusting JP, Kingwell BA, Exercise training increases basal nitric oxide production from the forearm in hypercholesterolemic patients. Arterioscler Thromb Vasc Biol 1999 19 2782 2787
25. Ellsworth DL, Croft DT Jr, Weyandt J, Sturtz LA, Blackburn HL, Burke A, Haberkorn MJ, McDyer FA, Jellema GL, van Laar R, Mamula KA, Chen Y, Vernalis MN, Intensive cardiovascular risk reduction induces sustainable changes in expression of genes and pathways important to vascular function. Circ Cardiovasc Genet 2014 7 151 160. doi: 10.1161/CIRCGENETICS.113.000121
26. Walther C, Gaede L, Adams V, Gelbrich G, Leichtle A, Erbs S, Sonnabend M, Fikenzer K, Körner A, Kiess W, Bruegel M, Thiery J, Schuler G, Effect of increased exercise in school children on physical fitness and endothelial progenitor cells: a prospective randomized trial. Circulation 2009 120 2251 2259. doi: 10.1161/CIRCULATIONAHA.109.865808
27. Werner C, Fürster T, Widmann T, Pöss J, Roggia C, Hanhoun M, Scharhag J, Büchner N, Meyer T, Kindermann W, Haendeler J, Böhm M, Laufs U, Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall. Circulation 2009 120 2438 2447. doi: 10.1161/CIRCULATIONAHA.109.861005
28. Tiso M, Schechter AN, Nitrate reduction to nitrite, nitric oxide and ammonia by gut bacteria under physiological conditions. PLoS One 2015 10 e0119712. doi: 10.1371/journal.pone.0119712
29. Rowe GC, Safdar A, Arany Z, Running forward: new frontiers in endurance exercise biology. Circulation 2014 129 798 810. doi: 10.1161/CIRCULATIONAHA.113.001590
30. Donohoe DR, Garge N, Zhang X, Sun W, O'Connell TM, Bunger MK, Bultman SJ, The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon. Cell Metab 2011 13 517 526. doi: 10.1016/j.cmet.2011.02.018
31. Evans CC, LePard KJ, Kwak JW, Stancukas MC, Laskowski S, Dougherty J, Moulton L, Glawe A, Wang Y, Leone V, Antonopoulos DA, Smith D, Chang EB, Ciancio MJ, Exercise prevents weight gain and alters the gut microbiota in a mouse model of high fat diet-induced obesity. PLoS One 2014 9 e92193. doi: 10.1371/journal.pone.0092193
32. Clarke SF, Murphy EF, O'Sullivan O, Lucey AJ, Humphreys M, Hogan A, Hayes P, O'Reilly M, Jeffery IB, Wood-Martin R, Kerins DM, Quigley E, Ross RP, O'Toole PW, Molloy MG, Falvey E, Shanahan F, Cotter PD, Exercise and associated dietary extremes impact on gut microbial diversity. Gut 2014 63 1913 1920. doi: 10.1136/gutjnl-2013-306541
33. Eckel RH, Jakicic JM, Ard JD, de Jesus JM, Houston Miller N, Hubbard VS, Lee IM, Lichtenstein AH, Loria CM, Millen BE, Nonas CA, Sacks FM, Smith SC, Jr, Svetkey LP, Wadden TA, Yanovski SZ, Kendall KA, Morgan LC, Trisolini MG, Velasco G, Wnek J, Anderson JL, Halperin JL, Albert NM, Bozkurt B, Brindis RG, Curtis LH, DeMets D, Hochman JS, Kovacs RJ, Ohman EM, Pressler SJ, Sellke FW, Shen WK, Smith SC Jr, Tomaselli GF, American College of Cardiology/American Heart Association Task Force on Practice Guidelines 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2014 129 suppl 2 S76 S99. doi: 10.1161/01.cir.0000437740.48606.d1
34. McCall DO, McGartland CP, McKinley MC, Patterson CC, Sharpe P, McCance DR, Young IS, Woodside JV, Dietary intake of fruits and vegetables improves microvascular function in hypertensive subjects in a dose-dependent manner. Circulation 2009 119 2153 2160. doi: 10.1161/CIRCULATIONAHA.108.831297
35. Corti R, Flammer AJ, Hollenberg NK, Lüscher TF, Cocoa and cardiovascular health. Circulation 2009 119 1433 1441. doi: 10.1161/CIRCULATIONAHA.108.827022
36. Robich MP, Osipov RM, Nezafat R, Feng J, Clements RT, Bianchi C, Boodhwani M, Coady MA, Laham RJ, Sellke FW, Resveratrol improves myocardial perfusion in a swine model of hypercholesterolemia and chronic myocardial ischemia. Circulation 2010 122 suppl S142 S149. doi: 10.1161/CIRCULATIONAHA.109.920132
37. Albenberg LG, Wu GD, Diet and the intestinal microbiome: associations, functions, and implications for health and disease. Gastroenterology 2014 146 1564 1572. doi: 10.1053/j.gastro.2014.01.058
38. Wang Z, Roberts AB, Buffa JA, Levison BS, Zhu W, Org E, Gu X, Huang Y, Zamanian-Daryoush M, Culley MK, DiDonato AJ, Fu X, Hazen JE, Krajcik D, DiDonato JA, Lusis AJ, Hazen SL, Non-lethal inhibition of gut microbial trimethylamine production for the treatment of atherosclerosis. Cell 2015 163 1585 1595. doi: 10.1016/j.cell.2015.11.055
39. De Filippis F, Pellegrini N, Vannini L, Jeffery IB, La Storia A, Laghi L, Serrazanetti DI, Di Cagno R, Ferrocino I, Lazzi C, Turroni S, Cocolin L, Brigidi P, Neviani E, Gobbetti M, O'Toole PW, Ercolini D, High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome [published online ahead of print September 28, 2015]. Gut 2015. doi: 10.1136/gutjnl-2015-309957. http://gut.bmj.com/content/early/2015/09/03/gutjnl-2015-309957.long. Accessed January 9, 2016
40. Ott SJ, El Mokhtari NE, Musfeldt M, Hellmig S, Freitag S, Rehman A, Kühbacher T, Nikolaus S, Namsolleck P, Blaut M, Hampe J, Sahly H, Reinecke A, Haake N, Günther R, Krüger D, Lins M, Herrmann G, Fölsch UR, Simon R, Schreiber S, Detection of diverse bacterial signatures in atherosclerotic lesions of patients with coronary heart disease. Circulation 2006 113 929 937. doi: 10.1161/CIRCULATIONAHA.105.579979
41. Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, Gomez Sanchez MA, Krishna Kumar R, Landzberg M, Machado RF, Olschewski H, Robbins IM, Souza R, Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2013 62 suppl D34 D41. doi: 10.1016/j.jacc.2013.10.029
42. Dickson RP, Erb-Downward JR, Huffnagle GB, Homeostasis and its disruption in the lung microbiome. Am J Physiol Lung Cell Mol Physiol 2015 309 L1047 L1055. doi: 10.1152/ajplung.00279.2015
43. Prakash A, Sundar SV, Zhu YG, Tran A, Lee JW, Lowell C, Hellman J, Lung ischemia-reperfusion is a sterile inflammatory process influenced by commensal microbiota in mice. Shock 2015 44 272 279. doi: 10.1097/SHK.0000000000000415
44. Kim JH, Yoon YJ, Lee J, Choi EJ, Yi N, Park KS, Park J, Lötvall J, Kim YK, Gho YS, Outer membrane vesicles derived from Escherichia coli up-regulate expression of endothelial cell adhesion molecules in vitro and in vivo. PLoS One 2013 8 e59276. doi: 10.1371/journal.pone.0059276
45. Ho KJ, Xiong L, Hubert NJ, Nadimpalli A, Wun K, Chang EB, Kibbe MR, Vancomycin treatment and butyrate supplementation modulate gut microbe composition and severity of neointimal hyperplasia after arterial injury. Physiol Rep 2015 3 e12627. doi: 10.14814/phy2.12627
46. Lawrie A, Hameed AG, Chamberlain J, Arnold N, Kennerley A, Hopkinson K, Pickworth J, Kiely DG, Crossman DC, Francis SE, Paigen diet-fed apolipoprotein E knockout mice develop severe pulmonary hypertension in an interleukin-1-dependent manner. Am J Pathol 2011 179 1693 1705. doi: 10.1016/j.ajpath.2011.06.037
47. Archer SL, Johnson GJ, Gebhard RL, Castleman WL, Levine AS, Westcott JY, Voelkel NF, Nelson DP, Weir EK, Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension. J Appl Physiol (1985) 1989 66 1662 1673
48. Forslund K, Hildebrand F, Nielsen T, Falony G, Le Chatelier E, Sunagawa S, Prifti E, Vieira-Silva S, Gudmundsdottir V, Krogh Pedersen H, Arumugam M, Kristiansen K, Voigt AY, Vestergaard H, Hercog R, Igor Costea P, Kultima JR, Li J, Jørgensen T, Levenez F, Dore J, Nielsen HB, Brunak S, Raes J, Hansen T, Wang J, Ehrlich SD, Bork P, Pedersen O, MetaHIT Consortium Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota. Nature 2015 528 262 266. doi: 10.1038/nature15766