메뉴 건너뛰기




Volumn 43, Issue 4, 2016, Pages 494-502

Immunological Aspects of Malignant Gliomas

Author keywords

Anergy; Astrocytromas; Checkpoint inhibitors; Cytokine Modulation; Dendritic Cell vaccination; Glioblatoma Multiforma; Glioma; Immuno Resistance; Immunotherapy; Neuro oncology Surgical; Neuroimmunology

Indexed keywords

ARTICLE; CANCER IMMUNOLOGY; CANCER IMMUNOTHERAPY; CANCER PROGNOSIS; CLINICAL FEATURE; CLINICAL TRIAL (TOPIC); GLIOBLASTOMA; HUMAN; KNOWLEDGE; MELANOMA; PRIORITY JOURNAL; SYNAPSE; BRAIN NEOPLASMS; IMMUNOLOGY; IMMUNOTHERAPY; PROCEDURES;

EID: 84975743877     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/cjn.2016.34     Document Type: Article
Times cited : (12)

References (98)
  • 2
    • 84873397441 scopus 로고    scopus 로고
    • Mechanisms of gliomagenesis and glioblastoma multiforme variants
    • Karsy M. Mechanisms of gliomagenesis and glioblastoma multiforme variants. Folia Neuropathol. 2012;50:301-21.
    • (2012) Folia Neuropathol , vol.50 , pp. 301-321
    • Karsy, M.1
  • 3
    • 84867598511 scopus 로고    scopus 로고
    • Primary human glioblastomas-prognostic value of clinical and histopathological parameters
    • Habberstad AH, Lind-Landström T, Sundstrøm S, Torp SH. Primary human glioblastomas-prognostic value of clinical and histopathological parameters. Clin Neuropathol. 2012;31:361-8.
    • (2012) Clin Neuropathol , vol.31 , pp. 361-368
    • Habberstad, A.H.1    Lind-Landström, T.2    Sundstrøm, S.3    Torp, S.H.4
  • 4
    • 1042301341 scopus 로고    scopus 로고
    • Factors influencing survival in high-grade gliomas
    • Buckner JC. Factors influencing survival in high-grade gliomas. Semin Oncol. 2003;30:10-4.
    • (2003) Semin Oncol , vol.30 , pp. 10-14
    • Buckner, J.C.1
  • 5
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-96.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    Van Den Bent, M.J.3
  • 6
    • 0035843243 scopus 로고    scopus 로고
    • Brain tumors
    • DeAngelis LM. Brain tumors. N Engl J Med. 2001;344:114-23.
    • (2001) N Engl J Med , vol.344 , pp. 114-123
    • DeAngelis, L.M.1
  • 7
    • 79960494838 scopus 로고    scopus 로고
    • The efficacy of carmustine wafers for older patients with glioblastoma multiforme: Prolonging survival
    • Chaichana KL, Zaidi H, Pendleton C, et al. The efficacy of carmustine wafers for older patients with glioblastoma multiforme: prolonging survival. Neurol Res. 2011;33:759-64.
    • (2011) Neurol Res , vol.33 , pp. 759-764
    • Chaichana, K.L.1    Zaidi, H.2    Pendleton, C.3
  • 8
    • 63849314514 scopus 로고    scopus 로고
    • Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme
    • McGirt MJ, Than KD, Weingart JD, et al. Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme. J Neurosurg. 2009;110:583-8.
    • (2009) J Neurosurg , vol.110 , pp. 583-588
    • McGirt, M.J.1    Than, K.D.2    Weingart, J.D.3
  • 9
    • 84858594427 scopus 로고    scopus 로고
    • Temozolomide and other potential agents for the treatment of glioblastoma multiforme
    • Nagasawa DT, Chow F, Yew A, Kim W, Cremer N, Yang I. Temozolomide and other potential agents for the treatment of glioblastoma multiforme. Neurosurg Clin N Am. 2012;23: 307-22.
    • (2012) Neurosurg Clin N Am , vol.23 , pp. 307-322
    • Nagasawa, D.T.1    Chow, F.2    Yew, A.3    Kim, W.4    Cremer, N.5    Yang, I.6
  • 10
    • 84904902698 scopus 로고    scopus 로고
    • EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma
    • Weller M, van den Bent M, Hopkins K, et al. EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma. Lancet Oncol. 2014;s15:e395-403.
    • (2014) Lancet Oncol , vol.S15 , pp. e395-403
    • Weller, M.1    Van Den Bent, M.2    Hopkins, K.3
  • 11
    • 84941025149 scopus 로고    scopus 로고
    • Prospects of immune checkpoint modulators in the treatment of glioblastoma
    • Sep
    • Preusser M, Lim M, Hafler DA, Reardon DA, Sampson JH. Prospects of immune checkpoint modulators in the treatment of glioblastoma. Nat Rev Neurol. 2015, Sep;11(9):504-14.
    • (2015) Nat Rev Neurol , vol.11 , Issue.9 , pp. 504-514
    • Preusser, M.1    Lim, M.2    Hafler, D.A.3    Reardon, D.A.4    Sampson, J.H.5
  • 12
    • 77954939175 scopus 로고    scopus 로고
    • Prostate cancer as a model for tumour immunotherapy
    • Drake CG. Prostate cancer as a model for tumour immunotherapy. Nat Rev Immunol. 2010;10:580-93.
    • (2010) Nat Rev Immunol , vol.10 , pp. 580-593
    • Drake, C.G.1
  • 13
    • 81255138488 scopus 로고    scopus 로고
    • Ipilimumab: An anti-CTLA-4 anti-body for metastatic melanoma
    • Lipson EJ, Drake CG. Ipilimumab: an anti-CTLA-4 anti-body for metastatic melanoma. Clin Cancer Res. 2011;17:6958-62.
    • (2011) Clin Cancer Res , vol.17 , pp. 6958-6962
    • Lipson, E.J.1    Drake, C.G.2
  • 14
    • 84937523825 scopus 로고    scopus 로고
    • Concepts of immunotherapy for glioma
    • Patel MA, Pardoll DM. Concepts of immunotherapy for glioma. J Neurooncol. 2015;123:323-30.
    • (2015) J Neurooncol , vol.123 , pp. 323-330
    • Patel, M.A.1    Pardoll, D.M.2
  • 15
    • 0034618869 scopus 로고    scopus 로고
    • The HLA system. First of two parts
    • Klein J, Sato A. The HLA system. First of two parts. N Engl J Med. 2000;343:702-9.
    • (2000) N Engl J Med , vol.343 , pp. 702-709
    • Klein, J.1    Sato, A.2
  • 18
    • 0037191792 scopus 로고    scopus 로고
    • Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
    • Stefanova I, Dorfman JR, Germain RN. Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature. 2002;420:429-34.
    • (2002) Nature , vol.420 , pp. 429-434
    • Stefanova, I.1    Dorfman, J.R.2    Germain, R.N.3
  • 19
    • 0043268924 scopus 로고    scopus 로고
    • Dynamics of cell surface molecules during T cell recognition
    • Davis MM, Krogsgaard M, Huppa JB, et al. Dynamics of cell surface molecules during T cell recognition. Annu Rev Biochem. 2003;72:717-42.
    • (2003) Annu Rev Biochem , vol.72 , pp. 717-742
    • Davis, M.M.1    Krogsgaard, M.2    Huppa, J.B.3
  • 20
    • 0036379786 scopus 로고    scopus 로고
    • All in the head: Obstacles for immune rejection of brain tumours
    • Walker PR, Calzascia T, Dietrich PY. All in the head: obstacles for immune rejection of brain tumours. Immunology. 2002;107:28-38.
    • (2002) Immunology , vol.107 , pp. 28-38
    • Walker, P.R.1    Calzascia, T.2    Dietrich, P.Y.3
  • 21
    • 0034982596 scopus 로고    scopus 로고
    • Immunological update on multiple sclerosis
    • Hohlfeld R, Wekerle H. Immunological update on multiple sclerosis. Curr Opin Neurol. 2001;14:299-304.
    • (2001) Curr Opin Neurol , vol.14 , pp. 299-304
    • Hohlfeld, R.1    Wekerle, H.2
  • 22
    • 0035017442 scopus 로고    scopus 로고
    • The role of T-cell-mediated mechanisms in virus infections of the nervous system
    • Dörries R. The role of T-cell-mediated mechanisms in virus infections of the nervous system. Curr Top Microbiol Immunol. 2001;253:219-45.
    • (2001) Curr Top Microbiol Immunol , vol.253 , pp. 219-245
    • Dörries, R.1
  • 23
    • 0034193965 scopus 로고    scopus 로고
    • Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii
    • Fischer HG, Bonifas U, Reichmann G. Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii. J Immunol. 2000;164:4826-34.
    • (2000) J Immunol , vol.164 , pp. 4826-4834
    • Fischer, H.G.1    Bonifas, U.2    Reichmann, G.3
  • 24
    • 0032936851 scopus 로고    scopus 로고
    • The cell biology of the blood-brain barrier
    • Rubin LL, Staddon JM. The cell biology of the blood-brain barrier. Annu Rev Neurosci. 1999;22:11-28.
    • (1999) Annu Rev Neurosci , vol.22 , pp. 11-28
    • Rubin, L.L.1    Staddon, J.M.2
  • 25
    • 2142714017 scopus 로고    scopus 로고
    • Monoclonal antibodies as therapeutic agents for cancer
    • Harris M. Monoclonal antibodies as therapeutic agents for cancer. Lancet Oncol. 2004;5:292-302.
    • (2004) Lancet Oncol , vol.5 , pp. 292-302
    • Harris, M.1
  • 26
    • 34249693089 scopus 로고    scopus 로고
    • Novel antibodies as anticancer agents
    • Zafir-Lavie I, Michaeli Y, Reiter Y. Novel antibodies as anticancer agents. Oncogene. 2007;26:3714-33.
    • (2007) Oncogene , vol.26 , pp. 3714-3733
    • Zafir-Lavie, I.1    Michaeli, Y.2    Reiter, Y.3
  • 27
    • 0034131423 scopus 로고    scopus 로고
    • An overview of cancer immunotherapy
    • Davis ID. An overview of cancer immunotherapy. Immunol Cell Biol. 2000;78:179-95.
    • (2000) Immunol Cell Biol , vol.78 , pp. 179-195
    • Davis, I.D.1
  • 28
    • 0037342270 scopus 로고    scopus 로고
    • Quantitating protein synthesis, degradation, and endogenous antigen processing
    • Princiotta MF, Finzi D, Qian SB, et al. Quantitating protein synthesis, degradation, and endogenous antigen processing, Immunity. 2003;18:343-54.
    • (2003) Immunity , vol.18 , pp. 343-354
    • Princiotta, M.F.1    Finzi, D.2    Qian, S.B.3
  • 29
    • 3142710121 scopus 로고    scopus 로고
    • HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells
    • Liu G, Ying H, Zeng G, Wheeler CJ, Black KL, Yu JS. HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells. Cancer Res. 2004;64:4980-6.
    • (2004) Cancer Res , vol.64 , pp. 4980-4986
    • Liu, G.1    Ying, H.2    Zeng, G.3    Wheeler, C.J.4    Black, K.L.5    Yu, J.S.6
  • 30
    • 33846886376 scopus 로고    scopus 로고
    • Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics
    • Zhang JG, Eguchi J, Kruse CA, et al. Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. Clin Cancer Res. 2007;13:566-75.
    • (2007) Clin Cancer Res , vol.13 , pp. 566-575
    • Zhang, J.G.1    Eguchi, J.2    Kruse, C.A.3
  • 31
    • 33845698912 scopus 로고    scopus 로고
    • Expression of nine tumour antigens in a series of human glioblastoma multiforme: Interest of EGFRvIII, IL-13Ralpha2, gp100 and TRP-2 for immunotherapy
    • Saikali S, Avril T, Collet B, et al. Expression of nine tumour antigens in a series of human glioblastoma multiforme: interest of EGFRvIII, IL-13Ralpha2, gp100 and TRP-2 for immunotherapy. J Neurooncol. 2007;81:139-48.
    • (2007) J Neurooncol , vol.81 , pp. 139-148
    • Saikali, S.1    Avril, T.2    Collet, B.3
  • 32
    • 0346995276 scopus 로고    scopus 로고
    • Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model
    • Prins RM, Odesa SK, Liau LM. Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model. Cancer Res. 2003;63:8487-91.
    • (2003) Cancer Res , vol.63 , pp. 8487-8491
    • Prins, R.M.1    Odesa, S.K.2    Liau, L.M.3
  • 33
    • 0025877114 scopus 로고
    • The cause of death in patients with glioblastoma is multifactorial: Clinical factors and autopsyfindings in 117 cases of supratentorial glioblastoma in adults
    • Silbergeld DL, Rostomily RC, Alvord EC Jr. The cause of death in patients with glioblastoma is multifactorial: clinical factors and autopsyfindings in 117 cases of supratentorial glioblastoma in adults. J Neurooncol. 1991;10:179-85.
    • (1991) J Neurooncol , vol.10 , pp. 179-185
    • Silbergeld, D.L.1    Rostomily, R.C.2    Alvord, E.C.3
  • 34
    • 65649149438 scopus 로고    scopus 로고
    • Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q
    • Aghi MK, Batchelor TT, Louis DN, Barker FG, Curry WT Jr. Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q. J Neurooncol. 2009;93:115-20.
    • (2009) J Neurooncol , vol.93 , pp. 115-120
    • Aghi, M.K.1    Batchelor, T.T.2    Louis, D.N.3    Barker, F.G.4    Curry, W.T.5
  • 35
    • 33846118474 scopus 로고    scopus 로고
    • Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
    • Parsa AT, Waldron JS, Panner A, et al. Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med. 2007;13:84-8.
    • (2007) Nat Med , vol.13 , pp. 84-88
    • Parsa, A.T.1    Waldron, J.S.2    Panner, A.3
  • 36
    • 0036935383 scopus 로고    scopus 로고
    • Cytokine and cytokine receptor mRNA expression in human glioblastomas: Evidence of Th1, Th2 and Th3 cytokine dysregulation
    • Hao C, Parney IF, Roa WH, Turner J, Petruk KC, Ramsay DA. Cytokine and cytokine receptor mRNA expression in human glioblastomas: evidence of Th1, Th2 and Th3 cytokine dysregulation. Acta Neuropathol. 2002;103:171-8.
    • (2002) Acta Neuropathol , vol.103 , pp. 171-178
    • Hao, C.1    Parney, I.F.2    Roa, W.H.3    Turner, J.4    Petruk, K.C.5    Ramsay, D.A.6
  • 37
    • 33645502885 scopus 로고    scopus 로고
    • Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma
    • Fecci PE, Mitchell DA, Whitesides JF, et al. Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma. Cancer Res. 2006;66:3294-302.
    • (2006) Cancer Res , vol.66 , pp. 3294-3302
    • Fecci, P.E.1    Mitchell, D.A.2    Whitesides, J.F.3
  • 38
    • 33748481603 scopus 로고    scopus 로고
    • An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme
    • El Andaloussi A, Lesniak MS. An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme. Neurooncol. 2006;8:234-43.
    • (2006) Neurooncol , vol.8 , pp. 234-243
    • El Andaloussi, A.1    Lesniak, M.S.2
  • 39
    • 84937525661 scopus 로고    scopus 로고
    • The role of regulatory T cells and microglia in Glioblastoma-associated immunosuppression
    • See AP, Parker JJ, Waziri A. The role of regulatory T cells and microglia in Glioblastoma-associated immunosuppression. J Neurooncol. 2015;123:405-12.
    • (2015) J Neurooncol , vol.123 , pp. 405-412
    • See, A.P.1    Parker, J.J.2    Waziri, A.3
  • 40
    • 0038615946 scopus 로고    scopus 로고
    • Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo
    • Choe G, Horvath S, Cloughesy TF, et al. Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo. Cancer Res. 2003;63:2742-6.
    • (2003) Cancer Res , vol.63 , pp. 2742-2746
    • Choe, G.1    Horvath, S.2    Cloughesy, T.F.3
  • 41
    • 0036094711 scopus 로고    scopus 로고
    • Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival
    • Ermoian RP, Furniss CS, Lamborn KR, et al. Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival. Clin Cancer Res. 2002;8:1100-6.
    • (2002) Clin Cancer Res , vol.8 , pp. 1100-1106
    • Ermoian, R.P.1    Furniss, C.S.2    Lamborn, K.R.3
  • 42
  • 43
    • 12444328362 scopus 로고    scopus 로고
    • Cell-mediated immunotherapy: A new approach to the treatment of malignant glioma
    • Yang L, Ng KY, Lillehei KO. Cell-mediated immunotherapy: a new approach to the treatment of malignant glioma. Cancer Control. 2003;10:138-47.
    • (2003) Cancer Control , vol.10 , pp. 138-147
    • Yang, L.1    Ng, K.Y.2    Lillehei, K.O.3
  • 45
    • 0742270321 scopus 로고    scopus 로고
    • Hide-and-seek in the brain: A role for HLA-G mediating immune privilege for glioma cells
    • Wiendl H, Mitsdoerffer M, Weller M. Hide-and-seek in the brain: a role for HLA-G mediating immune privilege for glioma cells. Semin Cancer Biol. 2003;13:343-51.
    • (2003) Semin Cancer Biol , vol.13 , pp. 343-351
    • Wiendl, H.1    Mitsdoerffer, M.2    Weller, M.3
  • 47
    • 33847052535 scopus 로고    scopus 로고
    • Mechanisms of malignant glioma immune resistance and sources of immunosuppression
    • Gomez GG, Kruse CA. Mechanisms of malignant glioma immune resistance and sources of immunosuppression. Gene Ther Mol Biol. 2006;10:133-46.
    • (2006) Gene Ther Mol Biol , vol.10 , pp. 133-146
    • Gomez, G.G.1    Kruse, C.A.2
  • 48
    • 34848812545 scopus 로고    scopus 로고
    • Comparative analysis of peripheral and localised cytokine secretion in glioblastoma patients
    • Zisakis A, Piperi C, Themistocleous MS, et al. Comparative analysis of peripheral and localised cytokine secretion in glioblastoma patients. Cytokine. 2007;39:99-105.
    • (2007) Cytokine , vol.39 , pp. 99-105
    • Zisakis, A.1    Piperi, C.2    Themistocleous, M.S.3
  • 49
    • 67349223911 scopus 로고    scopus 로고
    • Dendritic-cell-and peptide-based vaccination strategies for glioma
    • Yamanaka R. Dendritic-cell-and peptide-based vaccination strategies for glioma, Neurosurg Rev. 2009;32:265-73.
    • (2009) Neurosurg Rev , vol.32 , pp. 265-273
    • Yamanaka, R.1
  • 50
    • 79961118475 scopus 로고    scopus 로고
    • Phase I/IIa trial of autologous formalin-fixed tumor vaccine concomitant with fractionated radiotherapy for newly diagnosed glioblastoma: Clinical article
    • Muragaki Y, Maruyama T, Iseki H, et al. Phase I/IIa trial of autologous formalin-fixed tumor vaccine concomitant with fractionated radiotherapy for newly diagnosed glioblastoma: clinical article. J Neurosurg. 2011;115:248-55.
    • (2011) J Neurosurg , vol.115 , pp. 248-255
    • Muragaki, Y.1    Maruyama, T.2    Iseki, H.3
  • 51
    • 0033000339 scopus 로고    scopus 로고
    • Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans
    • Palu G, Cavaggioni A, Calvi P, et al. Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans. Gene Ther. 1999;6:330-7.
    • (1999) Gene Ther , vol.6 , pp. 330-337
    • Palu, G.1    Cavaggioni, A.2    Calvi, P.3
  • 52
    • 0023813406 scopus 로고
    • Adoptive immunotherapy for recurrent glioblastoma multiforme using lymphokine activated killer cells and recombinant interleukin-2
    • Merchant RE, Grant AJ, Merchant LH, Young HF. Adoptive immunotherapy for recurrent glioblastoma multiforme using lymphokine activated killer cells and recombinant interleukin-2. Cancer. 1988;62:665-71.
    • (1988) Cancer , vol.62 , pp. 665-671
    • Merchant, R.E.1    Grant, A.J.2    Merchant, L.H.3    Young, H.F.4
  • 55
    • 84862859820 scopus 로고    scopus 로고
    • Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
    • Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366:2443-54.
    • (2012) N Engl J Med , vol.366 , pp. 2443-2454
    • Topalian, S.L.1    Hodi, F.S.2    Brahmer, J.R.3
  • 56
    • 84879777241 scopus 로고    scopus 로고
    • Nivolumab plus ipilimumab in advanced melanoma
    • Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. 2013;369:122-33.
    • (2013) N Engl J Med , vol.369 , pp. 122-133
    • Wolchok, J.D.1    Kluger, H.2    Callahan, M.K.3
  • 57
    • 84925221855 scopus 로고    scopus 로고
    • PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
    • Ansell SM, Lesokhin AM, Borrello I, et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med. 2015;372:311-9.
    • (2015) N Engl J Med , vol.372 , pp. 311-319
    • Ansell, S.M.1    Lesokhin, A.M.2    Borrello, I.3
  • 58
    • 84929572937 scopus 로고    scopus 로고
    • Nivolumab for metastatic renal cell carcinoma: Results of a randomized phase II trial
    • Motzer RJ, Rini BI, McDermott DF, et al. Nivolumab for metastatic renal cell carcinoma: results of a randomized phase II trial. J Clin Oncol. 2015;33:1430-7.
    • (2015) J Clin Oncol , vol.33 , pp. 1430-1437
    • Motzer, R.J.1    Rini, B.I.2    McDermott, D.F.3
  • 59
    • 84924901863 scopus 로고    scopus 로고
    • Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): A phase 2, single-arm trial
    • Rizvi NA, Mazières J, Planchard D, et al. Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol. 2015;16:257-65.
    • (2015) Lancet Oncol , vol.16 , pp. 257-265
    • Rizvi, N.A.1    Mazières, J.2    Planchard, D.3
  • 60
    • 84975739760 scopus 로고    scopus 로고
    • Opdivo (nivolumab) [prescribing information] (Bristol-Myers Squibb Company, 2014)
    • Opdivo (nivolumab) [prescribing information] http://www.opdivo. bmscustomer connect.com/gateway (Bristol-Myers Squibb Company, 2014).
  • 61
    • 84975732891 scopus 로고    scopus 로고
    • Keytruda (pembrolizumab) [prescribing information] (Merck & Co., Inc. 2015)
    • Keytruda (pembrolizumab) [prescribing information] http://www. merck.com/product/usa/pi-circulars/k/keytruda/keytruda-pi.pdf (Merck & Co., Inc. 2015).
  • 62
    • 84937429313 scopus 로고    scopus 로고
    • A phase 2 study of concurrent radiation therapy, temozolomide, and the histone deacetylase inhibitor valproic acid for patients with glioblastoma
    • Krauze AV, Myrehaug SD, Chang MG, et al. A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma. Int J Radiat Oncol Biol Phys. 2015;92:986-92.
    • (2015) Int J Radiat Oncol Biol Phys , vol.92 , pp. 986-992
    • Krauze, A.V.1    Myrehaug, S.D.2    Chang, M.G.3
  • 63
    • 84904061991 scopus 로고    scopus 로고
    • Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors
    • Wainwright DA, Chang AL, Dey M, et al. Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors. Clin Cancer Res. 2014;20:5290-301.
    • (2014) Clin Cancer Res , vol.20 , pp. 5290-5301
    • Wainwright, D.A.1    Chang, A.L.2    Dey, M.3
  • 64
    • 84907498834 scopus 로고    scopus 로고
    • Blocking immunosuppressive checkpoints for glioma therapy: The more the Merrier!
    • Castro MG, Baker GJ, Lowenstein PR. Blocking immunosuppressive checkpoints for glioma therapy: the more the Merrier! Clin Cancer Res. 2014;20:5147-9.
    • (2014) Clin Cancer Res , vol.20 , pp. 5147-5149
    • Castro, M.G.1    Baker, G.J.2    Lowenstein, P.R.3
  • 65
    • 0037108683 scopus 로고    scopus 로고
    • Direct detection and quantitation of a distinct T-cell epitope derived from tumor-specific epithelial cell-associated mucin using human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells
    • Cohen CJ, Hoffmann N, Farago M, Hoogenboom HR, Eisenbach L, Reiter Y. Direct detection and quantitation of a distinct T-cell epitope derived from tumor-specific epithelial cell-associated mucin using human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells. Cancer Res. 2002;62:5835-44.
    • (2002) Cancer Res , vol.62 , pp. 5835-5844
    • Cohen, C.J.1    Hoffmann, N.2    Farago, M.3    Hoogenboom, H.R.4    Eisenbach, L.5    Reiter, Y.6
  • 66
    • 0037047110 scopus 로고    scopus 로고
    • Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC-restricted T cell receptor-like specificity
    • Denkberg G, Cohen CJ, Lev A, Chames P, Hoogenboom HR, Reiter Y. Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC-restricted T cell receptor-like specificity. Proc Natl Acad Sci. 2002;99:9421-6.
    • (2002) Proc Natl Acad Sci , vol.99 , pp. 9421-9426
    • Denkberg, G.1    Cohen, C.J.2    Lev, A.3    Chames, P.4    Hoogenboom, H.R.5    Reiter, Y.6
  • 67
    • 0037446653 scopus 로고    scopus 로고
    • Direct phenotypic analysis of human MHC class i antigen presentation: Visualization, quantitation, and in situ detection of human viral epitopes using peptide-specific, MHC-restricted human recombinant antibodies
    • Cohen CJ, Sarig O, Yamano Y, Tomaru U, Jacobson S, Reiter Y. Direct phenotypic analysis of human MHC class I antigen presentation: visualization, quantitation, and in situ detection of human viral epitopes using peptide-specific, MHC-restricted human recombinant antibodies. J Immunol. 2003;170: 4349-4361.
    • (2003) J Immunol , vol.170 , pp. 4349-4361
    • Cohen, C.J.1    Sarig, O.2    Yamano, Y.3    Tomaru, U.4    Jacobson, S.5    Reiter, Y.6
  • 68
    • 0037108364 scopus 로고    scopus 로고
    • Modification of a tumorderived peptide at an HLA-A2 anchor residue can alter the conformation of the MHC-peptide complex: Probing with TCRlike recombinant antibodies
    • Denkberg G, Klechevsky E, Reiter Y. Modification of a tumorderived peptide at an HLA-A2 anchor residue can alter the conformation of the MHC-peptide complex: probing with TCRlike recombinant antibodies. J Immunol. 2002;169:4399-407.
    • (2002) J Immunol , vol.169 , pp. 4399-4407
    • Denkberg, G.1    Klechevsky, E.2    Reiter, Y.3
  • 70
    • 0035107548 scopus 로고    scopus 로고
    • Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell in-filtration
    • Yu JS, Wheeler CJ, Zeltzer PM, et al. Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell in-filtration. Cancer Res. 2001;61:842-7.
    • (2001) Cancer Res , vol.61 , pp. 842-847
    • Yu, J.S.1    Wheeler, C.J.2    Zeltzer, P.M.3
  • 71
    • 23044479028 scopus 로고    scopus 로고
    • Dendritic cell vaccination in glioblastoma patients induces systemic andintracranial T-cell responses modulated by the local central nervous system tumor microenvironment
    • Liau LM, Prins RM, Kiertscher SM, et al. Dendritic cell vaccination in glioblastoma patients induces systemic andintracranial T-cell responses modulated by the local central nervous system tumor microenvironment. Clin Cancer Res. 2005;11:5515-25.
    • (2005) Clin Cancer Res , vol.11 , pp. 5515-5525
    • Liau, L.M.1    Prins, R.M.2    Kiertscher, S.M.3
  • 72
    • 78149254368 scopus 로고    scopus 로고
    • Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
    • Sampson JH, Heimberger AB, Archer GE, et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J Clin Oncol. 2010;28:4722-9.
    • (2010) J Clin Oncol , vol.28 , pp. 4722-4729
    • Sampson, J.H.1    Heimberger, A.B.2    Archer, G.E.3
  • 73
    • 0034784610 scopus 로고    scopus 로고
    • Preliminary results of active specific immunization with modified tumor cell vaccine in glioblastoma multiforme
    • Schneider T, Gerhards R, Kirches E, Firsching R. Preliminary results of active specific immunization with modified tumor cell vaccine in glioblastoma multiforme. J Neuro-Oncol. 2001;53:39-46.
    • (2001) J Neuro-Oncol , vol.53 , pp. 39-46
    • Schneider, T.1    Gerhards, R.2    Kirches, E.3    Firsching, R.4
  • 74
    • 16544392098 scopus 로고    scopus 로고
    • Antitumor vaccination of patients with glioblastoma multiforme: A pilot study to assess feasibility, safety, and clinical benefit
    • Steiner HH, Bonsanto MM, Beckhove P, et al. Antitumor vaccination of patients with glioblastoma multiforme: a pilot study to assess feasibility, safety, and clinical benefit. J Clin Oncol. 2004;22:4272-81.
    • (2004) J Clin Oncol , vol.22 , pp. 4272-4281
    • Steiner, H.H.1    Bonsanto, M.M.2    Beckhove, P.3
  • 75
    • 34347238993 scopus 로고    scopus 로고
    • Clinical trial of autologous formalin-fixed tumor vaccine for Glioblastoma multiforme patients
    • Ishikawa E, Tsuboi K, Yamamoto T, et al. Clinical trial of autologous formalin-fixed tumor vaccine for Glioblastoma multiforme patients. Cancer Sci. 2007;98:1226-33.
    • (2007) Cancer Sci , vol.98 , pp. 1226-1233
    • Ishikawa, E.1    Tsuboi, K.2    Yamamoto, T.3
  • 76
    • 79951602633 scopus 로고    scopus 로고
    • Targeted therapy for highgrade glioma with the TGF-beta2 inhibitor trabedersen: Results of a randomized and controlled phase IIb study
    • Bogdahn U, Hau P, Stockhammer G, et al. Targeted therapy for highgrade glioma with the TGF-beta2 inhibitor trabedersen: results of a randomized and controlled phase IIb study. Neuro-Oncol. 2011;13:132-42.
    • (2011) Neuro-Oncol , vol.13 , pp. 132-142
    • Bogdahn, U.1    Hau, P.2    Stockhammer, G.3
  • 77
    • 0026570661 scopus 로고
    • Treatment of recurrent malignant glioma by repeated intracerebral injections of human recombinant interleukin-2 alone or in combination with systemic interferon-?. Results of a phase i clinical trial
    • Merchant RE, McVicar DW, Merchant LH, Young HF. Treatment of recurrent malignant glioma by repeated intracerebral injections of human recombinant interleukin-2 alone or in combination with systemic interferon-? . Results of a phase I clinical trial. J Neuro-Oncol. 1992;12:75-83.
    • (1992) J Neuro-Oncol , vol.12 , pp. 75-83
    • Merchant, R.E.1    McVicar, D.W.2    Merchant, L.H.3    Young, H.F.4
  • 79
    • 30644457691 scopus 로고    scopus 로고
    • Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: Biological and clinical results
    • Colombo F, Barzon L, Franchin E, et al. Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results. Cancer Gene Ther. 2005;12: 835-48.
    • (2005) Cancer Gene Ther , vol.12 , pp. 835-848
    • Colombo, F.1    Barzon, L.2    Franchin, E.3
  • 80
    • 0028275672 scopus 로고
    • Randomised, controlled study of intratumoral recombinant ?-interferon treatment in newly diagnosed glioblastoma
    • Farkkila M, Jaaskelainen J, Kallio M, et al. Randomised, controlled study of intratumoral recombinant ?-interferon treatment in newly diagnosed glioblastoma. Br J Cancer. 1994;70:138-41.
    • (1994) Br J Cancer , vol.70 , pp. 138-141
    • Farkkila, M.1    Jaaskelainen, J.2    Kallio, M.3
  • 81
    • 33748580294 scopus 로고    scopus 로고
    • Maintenance treatment with interferon-gamma and low-dose cyclophosphamide for pediatric high-grade glioma
    • Wolff JE, Wagner S, Reinert C, et al. Maintenance treatment with interferon-gamma and low-dose cyclophosphamide for pediatric high-grade glioma. J Neuro-Oncol. 2006;79:315-21.
    • (2006) J Neuro-Oncol , vol.79 , pp. 315-321
    • Wolff, J.E.1    Wagner, S.2    Reinert, C.3
  • 82
    • 0025897346 scopus 로고
    • Recombinant interferon beta: A phase I-II trial in children with recurrent brain tumors
    • Allen J, Packer R, Bleyer A, Zeltzer P, Prados M, Nirenberg A. Recombinant interferon beta: a phase I-II trial in children with recurrent brain tumors. J Clin Oncol. 1991;9:783-8.
    • (1991) J Clin Oncol , vol.9 , pp. 783-788
    • Allen, J.1    Packer, R.2    Bleyer, A.3    Zeltzer, P.4    Prados, M.5    Nirenberg, A.6
  • 83
    • 0025055369 scopus 로고
    • Intratumor administration of beta-interferon in recurrent malignant gliomas. A Phase i clinical and laboratory study
    • Fetell MR, Housepian EM, Oster MW, et al. Intratumor administration of beta-interferon in recurrent malignant gliomas. A Phase I clinical and laboratory study. Cancer. 1990;65:78-83.
    • (1990) Cancer , vol.65 , pp. 78-83
    • Fetell, M.R.1    Housepian, E.M.2    Oster, M.W.3
  • 85
    • 0028929258 scopus 로고
    • Phase II evaluation of recombinant interferon alpha and BCNU in recurrent glioma
    • Buckner JC, Brown LD, Kugler JW, et al. Phase II evaluation of recombinant interferon alpha and BCNU in recurrent glioma. J Neurosurgery. 1995;82:430-5.
    • (1995) J Neurosurgery , vol.82 , pp. 430-435
    • Buckner, J.C.1    Brown, L.D.2    Kugler, J.W.3
  • 86
    • 0035878917 scopus 로고    scopus 로고
    • A Phase III study of radiation therapy plus carmustine with or without recombinant interferon-? in the treatment of patients with newly diagnosed high-grade glioma
    • Buckner JC, Schomberg PJ, McGinnis WL, et al. A Phase III study of radiation therapy plus carmustine with or without recombinant interferon-? in the treatment of patients with newly diagnosed high-grade glioma. Cancer. 2001;92:420-33.
    • (2001) Cancer , vol.92 , pp. 420-433
    • Buckner, J.C.1    Schomberg, P.J.2    McGinnis, W.L.3
  • 87
    • 56249111936 scopus 로고    scopus 로고
    • Phase i analysis of BCNU-impregnated biodegradable polymer wafers followed by systemic interferon alfa-2b in adults with recurrent glioblastoma multiforme
    • Olson JJ, McKenzie E, Skurski-Martin M, Zhang Z, Brat D, Phuphanich S. Phase I analysis of BCNU-impregnated biodegradable polymer wafers followed by systemic interferon alfa-2b in adults with recurrent glioblastoma multiforme. J Neuro-Oncol. 2008;90:293-9.
    • (2008) J Neuro-Oncol , vol.90 , pp. 293-299
    • Olson, J.J.1    McKenzie, E.2    Skurski-Martin, M.3    Zhang, Z.4    Brat, D.5    Phuphanich, S.6
  • 88
    • 40149090821 scopus 로고    scopus 로고
    • Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas
    • Okada H, Lieberman FS, Walter KA, et al. Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas. J Transl Med. 2007;5:67.
    • (2007) J Transl Med , vol.5 , pp. 67
    • Okada, H.1    Lieberman, F.S.2    Walter, K.A.3
  • 89
    • 0034047780 scopus 로고    scopus 로고
    • Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with highgrade glioma
    • Rand RW, Kreitman RJ, Patronas N, Varricchio F, Pastan I, Puri RK. Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with highgrade glioma. Clin Cancer Res. 2000;6:2157-65.
    • (2000) Clin Cancer Res , vol.6 , pp. 2157-2165
    • Rand, R.W.1    Kreitman, R.J.2    Patronas, N.3    Varricchio, F.4    Pastan, I.5    Puri, R.K.6
  • 90
    • 7444220033 scopus 로고    scopus 로고
    • Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12
    • Kikuchi T, Akasaki Y, Abe T, et al. Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12. J Immunother. 2004;27:452-9.
    • (2004) J Immunother , vol.27 , pp. 452-459
    • Kikuchi, T.1    Akasaki, Y.2    Abe, T.3
  • 91
    • 0022641036 scopus 로고
    • Interleukin-2 or autologous lymphokine-activated killer cell treatment of malignant glioma: Phase i trial
    • Jacobs SK, Wilson DJ, Kornblith PL, Grimm EA. Interleukin-2 or autologous lymphokine-activated killer cell treatment of malignant glioma: phase I trial. Cancer Res. 1986;46:2101-4.
    • (1986) Cancer Res , vol.46 , pp. 2101-2104
    • Jacobs, S.K.1    Wilson, D.J.2    Kornblith, P.L.3    Grimm, E.A.4
  • 92
    • 0025974603 scopus 로고
    • Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy
    • Lillehei KO, Mitchell DH, Johnson SD, McCleary EL, Kruse CA. Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy. Neurosurgery. 1991;28:16-23.
    • (1991) Neurosurgery , vol.28 , pp. 16-23
    • Lillehei, K.O.1    Mitchell, D.H.2    Johnson, S.D.3    McCleary, E.L.4    Kruse, C.A.5
  • 93
    • 0029145309 scopus 로고
    • Improved long term survival after intracavitary interleukin-2 and lymphokineactivated killer cells for adults with recurrent malignant glioma
    • Hayes RL, Koslow M, Hiesiger EM, et al. Improved long term survival after intracavitary interleukin-2 and lymphokineactivated killer cells for adults with recurrent malignant glioma. Cancer. 1995;76:840-52.
    • (1995) Cancer , vol.76 , pp. 840-852
    • Hayes, R.L.1    Koslow, M.2    Hiesiger, E.M.3
  • 94
    • 4344689067 scopus 로고    scopus 로고
    • Intracavitary placement of autologous lymphokine-activated killer (LAK) cells after resection of recurrent glioblastoma
    • Dillman RO, Duma CM, Schiltz PM, et al. Intracavitary placement of autologous lymphokine-activated killer (LAK) cells after resection of recurrent glioblastoma. J Immunother. 2004;27: 398-404.
    • (2004) J Immunother , vol.27 , pp. 398-404
    • Dillman, R.O.1    Duma, C.M.2    Schiltz, P.M.3
  • 95
    • 0032999584 scopus 로고    scopus 로고
    • Reduction of end-stage malignant glioma by injection with autologous cytotoxic T lymphocytes
    • Tsurushima H, Liu SQ, Tuboi K, et al. Reduction of end-stage malignant glioma by injection with autologous cytotoxic T lymphocytes. Jap J Cancer Res. 1999;90:536-45.
    • (1999) Jap J Cancer Res , vol.90 , pp. 536-545
    • Tsurushima, H.1    Liu, S.Q.2    Tuboi, K.3
  • 96
    • 0034044202 scopus 로고    scopus 로고
    • T cell adoptive immunotherapy of newly diagnosed gliomas
    • Plautz GE, Miller DW, Barnett GH, et al. T cell adoptive immunotherapy of newly diagnosed gliomas. Clin Cancer Res. 2000;6:2209-18.
    • (2000) Clin Cancer Res , vol.6 , pp. 2209-2218
    • Plautz, G.E.1    Miller, D.W.2    Barnett, G.H.3
  • 97
    • 84855604775 scopus 로고    scopus 로고
    • Challenges in Immunotherapy Presented by the Glioblastoma Multiforme Microenvironment
    • Jackson C, Ruzevick J, Phallen J, Belcaid Z, Lim M. Challenges in Immunotherapy Presented by the Glioblastoma Multiforme Microenvironment. Clin Dev Immunol. 2011;2011:732413, doi: 10.1155/2011/732413. Epub 2011 Dec 10.
    • (2011) Clin Dev Immunol , vol.2011 , pp. 732413
    • Jackson, C.1    Ruzevick, J.2    Phallen, J.3    Belcaid, Z.4    Lim, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.