-
1
-
-
0026318549
-
Increasing brain cancer rates in Canada
-
Mao YM, Desmeules M, Semenciw RM, Hill G, Gaudette L, Wigle DT. Increasing brain cancer rates in Canada. CMAJ. 1991;145:1583-91.
-
(1991)
CMAJ
, vol.145
, pp. 1583-1591
-
-
Mao, Y.M.1
Desmeules, M.2
Semenciw, R.M.3
Hill, G.4
Gaudette, L.5
Wigle, D.T.6
-
2
-
-
84873397441
-
Mechanisms of gliomagenesis and glioblastoma multiforme variants
-
Karsy M. Mechanisms of gliomagenesis and glioblastoma multiforme variants. Folia Neuropathol. 2012;50:301-21.
-
(2012)
Folia Neuropathol
, vol.50
, pp. 301-321
-
-
Karsy, M.1
-
3
-
-
84867598511
-
Primary human glioblastomas-prognostic value of clinical and histopathological parameters
-
Habberstad AH, Lind-Landström T, Sundstrøm S, Torp SH. Primary human glioblastomas-prognostic value of clinical and histopathological parameters. Clin Neuropathol. 2012;31:361-8.
-
(2012)
Clin Neuropathol
, vol.31
, pp. 361-368
-
-
Habberstad, A.H.1
Lind-Landström, T.2
Sundstrøm, S.3
Torp, S.H.4
-
4
-
-
1042301341
-
Factors influencing survival in high-grade gliomas
-
Buckner JC. Factors influencing survival in high-grade gliomas. Semin Oncol. 2003;30:10-4.
-
(2003)
Semin Oncol
, vol.30
, pp. 10-14
-
-
Buckner, J.C.1
-
5
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-96.
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
-
6
-
-
0035843243
-
Brain tumors
-
DeAngelis LM. Brain tumors. N Engl J Med. 2001;344:114-23.
-
(2001)
N Engl J Med
, vol.344
, pp. 114-123
-
-
DeAngelis, L.M.1
-
7
-
-
79960494838
-
The efficacy of carmustine wafers for older patients with glioblastoma multiforme: Prolonging survival
-
Chaichana KL, Zaidi H, Pendleton C, et al. The efficacy of carmustine wafers for older patients with glioblastoma multiforme: prolonging survival. Neurol Res. 2011;33:759-64.
-
(2011)
Neurol Res
, vol.33
, pp. 759-764
-
-
Chaichana, K.L.1
Zaidi, H.2
Pendleton, C.3
-
8
-
-
63849314514
-
Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme
-
McGirt MJ, Than KD, Weingart JD, et al. Gliadel (BCNU) wafer plus concomitant temozolomide therapy after primary resection of glioblastoma multiforme. J Neurosurg. 2009;110:583-8.
-
(2009)
J Neurosurg
, vol.110
, pp. 583-588
-
-
McGirt, M.J.1
Than, K.D.2
Weingart, J.D.3
-
9
-
-
84858594427
-
Temozolomide and other potential agents for the treatment of glioblastoma multiforme
-
Nagasawa DT, Chow F, Yew A, Kim W, Cremer N, Yang I. Temozolomide and other potential agents for the treatment of glioblastoma multiforme. Neurosurg Clin N Am. 2012;23: 307-22.
-
(2012)
Neurosurg Clin N Am
, vol.23
, pp. 307-322
-
-
Nagasawa, D.T.1
Chow, F.2
Yew, A.3
Kim, W.4
Cremer, N.5
Yang, I.6
-
10
-
-
84904902698
-
EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma
-
Weller M, van den Bent M, Hopkins K, et al. EANO guideline for the diagnosis and treatment of anaplastic gliomas and glioblastoma. Lancet Oncol. 2014;s15:e395-403.
-
(2014)
Lancet Oncol
, vol.S15
, pp. e395-403
-
-
Weller, M.1
Van Den Bent, M.2
Hopkins, K.3
-
11
-
-
84941025149
-
Prospects of immune checkpoint modulators in the treatment of glioblastoma
-
Sep
-
Preusser M, Lim M, Hafler DA, Reardon DA, Sampson JH. Prospects of immune checkpoint modulators in the treatment of glioblastoma. Nat Rev Neurol. 2015, Sep;11(9):504-14.
-
(2015)
Nat Rev Neurol
, vol.11
, Issue.9
, pp. 504-514
-
-
Preusser, M.1
Lim, M.2
Hafler, D.A.3
Reardon, D.A.4
Sampson, J.H.5
-
12
-
-
77954939175
-
Prostate cancer as a model for tumour immunotherapy
-
Drake CG. Prostate cancer as a model for tumour immunotherapy. Nat Rev Immunol. 2010;10:580-93.
-
(2010)
Nat Rev Immunol
, vol.10
, pp. 580-593
-
-
Drake, C.G.1
-
13
-
-
81255138488
-
Ipilimumab: An anti-CTLA-4 anti-body for metastatic melanoma
-
Lipson EJ, Drake CG. Ipilimumab: an anti-CTLA-4 anti-body for metastatic melanoma. Clin Cancer Res. 2011;17:6958-62.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6958-6962
-
-
Lipson, E.J.1
Drake, C.G.2
-
14
-
-
84937523825
-
Concepts of immunotherapy for glioma
-
Patel MA, Pardoll DM. Concepts of immunotherapy for glioma. J Neurooncol. 2015;123:323-30.
-
(2015)
J Neurooncol
, vol.123
, pp. 323-330
-
-
Patel, M.A.1
Pardoll, D.M.2
-
15
-
-
0034618869
-
The HLA system. First of two parts
-
Klein J, Sato A. The HLA system. First of two parts. N Engl J Med. 2000;343:702-9.
-
(2000)
N Engl J Med
, vol.343
, pp. 702-709
-
-
Klein, J.1
Sato, A.2
-
18
-
-
0037191792
-
Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes
-
Stefanova I, Dorfman JR, Germain RN. Self-recognition promotes the foreign antigen sensitivity of naive T lymphocytes. Nature. 2002;420:429-34.
-
(2002)
Nature
, vol.420
, pp. 429-434
-
-
Stefanova, I.1
Dorfman, J.R.2
Germain, R.N.3
-
19
-
-
0043268924
-
Dynamics of cell surface molecules during T cell recognition
-
Davis MM, Krogsgaard M, Huppa JB, et al. Dynamics of cell surface molecules during T cell recognition. Annu Rev Biochem. 2003;72:717-42.
-
(2003)
Annu Rev Biochem
, vol.72
, pp. 717-742
-
-
Davis, M.M.1
Krogsgaard, M.2
Huppa, J.B.3
-
20
-
-
0036379786
-
All in the head: Obstacles for immune rejection of brain tumours
-
Walker PR, Calzascia T, Dietrich PY. All in the head: obstacles for immune rejection of brain tumours. Immunology. 2002;107:28-38.
-
(2002)
Immunology
, vol.107
, pp. 28-38
-
-
Walker, P.R.1
Calzascia, T.2
Dietrich, P.Y.3
-
21
-
-
0034982596
-
Immunological update on multiple sclerosis
-
Hohlfeld R, Wekerle H. Immunological update on multiple sclerosis. Curr Opin Neurol. 2001;14:299-304.
-
(2001)
Curr Opin Neurol
, vol.14
, pp. 299-304
-
-
Hohlfeld, R.1
Wekerle, H.2
-
22
-
-
0035017442
-
The role of T-cell-mediated mechanisms in virus infections of the nervous system
-
Dörries R. The role of T-cell-mediated mechanisms in virus infections of the nervous system. Curr Top Microbiol Immunol. 2001;253:219-45.
-
(2001)
Curr Top Microbiol Immunol
, vol.253
, pp. 219-245
-
-
Dörries, R.1
-
23
-
-
0034193965
-
Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii
-
Fischer HG, Bonifas U, Reichmann G. Phenotype and functions of brain dendritic cells emerging during chronic infection of mice with Toxoplasma gondii. J Immunol. 2000;164:4826-34.
-
(2000)
J Immunol
, vol.164
, pp. 4826-4834
-
-
Fischer, H.G.1
Bonifas, U.2
Reichmann, G.3
-
24
-
-
0032936851
-
The cell biology of the blood-brain barrier
-
Rubin LL, Staddon JM. The cell biology of the blood-brain barrier. Annu Rev Neurosci. 1999;22:11-28.
-
(1999)
Annu Rev Neurosci
, vol.22
, pp. 11-28
-
-
Rubin, L.L.1
Staddon, J.M.2
-
25
-
-
2142714017
-
Monoclonal antibodies as therapeutic agents for cancer
-
Harris M. Monoclonal antibodies as therapeutic agents for cancer. Lancet Oncol. 2004;5:292-302.
-
(2004)
Lancet Oncol
, vol.5
, pp. 292-302
-
-
Harris, M.1
-
27
-
-
0034131423
-
An overview of cancer immunotherapy
-
Davis ID. An overview of cancer immunotherapy. Immunol Cell Biol. 2000;78:179-95.
-
(2000)
Immunol Cell Biol
, vol.78
, pp. 179-195
-
-
Davis, I.D.1
-
28
-
-
0037342270
-
Quantitating protein synthesis, degradation, and endogenous antigen processing
-
Princiotta MF, Finzi D, Qian SB, et al. Quantitating protein synthesis, degradation, and endogenous antigen processing, Immunity. 2003;18:343-54.
-
(2003)
Immunity
, vol.18
, pp. 343-354
-
-
Princiotta, M.F.1
Finzi, D.2
Qian, S.B.3
-
29
-
-
3142710121
-
HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells
-
Liu G, Ying H, Zeng G, Wheeler CJ, Black KL, Yu JS. HER-2, gp100, and MAGE-1 are expressed in human glioblastoma and recognized by cytotoxic T cells. Cancer Res. 2004;64:4980-6.
-
(2004)
Cancer Res
, vol.64
, pp. 4980-4986
-
-
Liu, G.1
Ying, H.2
Zeng, G.3
Wheeler, C.J.4
Black, K.L.5
Yu, J.S.6
-
30
-
-
33846886376
-
Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics
-
Zhang JG, Eguchi J, Kruse CA, et al. Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics. Clin Cancer Res. 2007;13:566-75.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 566-575
-
-
Zhang, J.G.1
Eguchi, J.2
Kruse, C.A.3
-
31
-
-
33845698912
-
Expression of nine tumour antigens in a series of human glioblastoma multiforme: Interest of EGFRvIII, IL-13Ralpha2, gp100 and TRP-2 for immunotherapy
-
Saikali S, Avril T, Collet B, et al. Expression of nine tumour antigens in a series of human glioblastoma multiforme: interest of EGFRvIII, IL-13Ralpha2, gp100 and TRP-2 for immunotherapy. J Neurooncol. 2007;81:139-48.
-
(2007)
J Neurooncol
, vol.81
, pp. 139-148
-
-
Saikali, S.1
Avril, T.2
Collet, B.3
-
32
-
-
0346995276
-
Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model
-
Prins RM, Odesa SK, Liau LM. Immunotherapeutic targeting of shared melanoma-associated antigens in a murine glioma model. Cancer Res. 2003;63:8487-91.
-
(2003)
Cancer Res
, vol.63
, pp. 8487-8491
-
-
Prins, R.M.1
Odesa, S.K.2
Liau, L.M.3
-
33
-
-
0025877114
-
The cause of death in patients with glioblastoma is multifactorial: Clinical factors and autopsyfindings in 117 cases of supratentorial glioblastoma in adults
-
Silbergeld DL, Rostomily RC, Alvord EC Jr. The cause of death in patients with glioblastoma is multifactorial: clinical factors and autopsyfindings in 117 cases of supratentorial glioblastoma in adults. J Neurooncol. 1991;10:179-85.
-
(1991)
J Neurooncol
, vol.10
, pp. 179-185
-
-
Silbergeld, D.L.1
Rostomily, R.C.2
Alvord, E.C.3
-
34
-
-
65649149438
-
Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q
-
Aghi MK, Batchelor TT, Louis DN, Barker FG, Curry WT Jr. Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q. J Neurooncol. 2009;93:115-20.
-
(2009)
J Neurooncol
, vol.93
, pp. 115-120
-
-
Aghi, M.K.1
Batchelor, T.T.2
Louis, D.N.3
Barker, F.G.4
Curry, W.T.5
-
35
-
-
33846118474
-
Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
-
Parsa AT, Waldron JS, Panner A, et al. Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med. 2007;13:84-8.
-
(2007)
Nat Med
, vol.13
, pp. 84-88
-
-
Parsa, A.T.1
Waldron, J.S.2
Panner, A.3
-
36
-
-
0036935383
-
Cytokine and cytokine receptor mRNA expression in human glioblastomas: Evidence of Th1, Th2 and Th3 cytokine dysregulation
-
Hao C, Parney IF, Roa WH, Turner J, Petruk KC, Ramsay DA. Cytokine and cytokine receptor mRNA expression in human glioblastomas: evidence of Th1, Th2 and Th3 cytokine dysregulation. Acta Neuropathol. 2002;103:171-8.
-
(2002)
Acta Neuropathol
, vol.103
, pp. 171-178
-
-
Hao, C.1
Parney, I.F.2
Roa, W.H.3
Turner, J.4
Petruk, K.C.5
Ramsay, D.A.6
-
37
-
-
33645502885
-
Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma
-
Fecci PE, Mitchell DA, Whitesides JF, et al. Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma. Cancer Res. 2006;66:3294-302.
-
(2006)
Cancer Res
, vol.66
, pp. 3294-3302
-
-
Fecci, P.E.1
Mitchell, D.A.2
Whitesides, J.F.3
-
38
-
-
33748481603
-
An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme
-
El Andaloussi A, Lesniak MS. An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme. Neurooncol. 2006;8:234-43.
-
(2006)
Neurooncol
, vol.8
, pp. 234-243
-
-
El Andaloussi, A.1
Lesniak, M.S.2
-
39
-
-
84937525661
-
The role of regulatory T cells and microglia in Glioblastoma-associated immunosuppression
-
See AP, Parker JJ, Waziri A. The role of regulatory T cells and microglia in Glioblastoma-associated immunosuppression. J Neurooncol. 2015;123:405-12.
-
(2015)
J Neurooncol
, vol.123
, pp. 405-412
-
-
See, A.P.1
Parker, J.J.2
Waziri, A.3
-
40
-
-
0038615946
-
Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo
-
Choe G, Horvath S, Cloughesy TF, et al. Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo. Cancer Res. 2003;63:2742-6.
-
(2003)
Cancer Res
, vol.63
, pp. 2742-2746
-
-
Choe, G.1
Horvath, S.2
Cloughesy, T.F.3
-
41
-
-
0036094711
-
Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival
-
Ermoian RP, Furniss CS, Lamborn KR, et al. Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival. Clin Cancer Res. 2002;8:1100-6.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1100-1106
-
-
Ermoian, R.P.1
Furniss, C.S.2
Lamborn, K.R.3
-
43
-
-
12444328362
-
Cell-mediated immunotherapy: A new approach to the treatment of malignant glioma
-
Yang L, Ng KY, Lillehei KO. Cell-mediated immunotherapy: a new approach to the treatment of malignant glioma. Cancer Control. 2003;10:138-47.
-
(2003)
Cancer Control
, vol.10
, pp. 138-147
-
-
Yang, L.1
Ng, K.Y.2
Lillehei, K.O.3
-
45
-
-
0742270321
-
Hide-and-seek in the brain: A role for HLA-G mediating immune privilege for glioma cells
-
Wiendl H, Mitsdoerffer M, Weller M. Hide-and-seek in the brain: a role for HLA-G mediating immune privilege for glioma cells. Semin Cancer Biol. 2003;13:343-51.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 343-351
-
-
Wiendl, H.1
Mitsdoerffer, M.2
Weller, M.3
-
47
-
-
33847052535
-
Mechanisms of malignant glioma immune resistance and sources of immunosuppression
-
Gomez GG, Kruse CA. Mechanisms of malignant glioma immune resistance and sources of immunosuppression. Gene Ther Mol Biol. 2006;10:133-46.
-
(2006)
Gene Ther Mol Biol
, vol.10
, pp. 133-146
-
-
Gomez, G.G.1
Kruse, C.A.2
-
48
-
-
34848812545
-
Comparative analysis of peripheral and localised cytokine secretion in glioblastoma patients
-
Zisakis A, Piperi C, Themistocleous MS, et al. Comparative analysis of peripheral and localised cytokine secretion in glioblastoma patients. Cytokine. 2007;39:99-105.
-
(2007)
Cytokine
, vol.39
, pp. 99-105
-
-
Zisakis, A.1
Piperi, C.2
Themistocleous, M.S.3
-
49
-
-
67349223911
-
Dendritic-cell-and peptide-based vaccination strategies for glioma
-
Yamanaka R. Dendritic-cell-and peptide-based vaccination strategies for glioma, Neurosurg Rev. 2009;32:265-73.
-
(2009)
Neurosurg Rev
, vol.32
, pp. 265-273
-
-
Yamanaka, R.1
-
50
-
-
79961118475
-
Phase I/IIa trial of autologous formalin-fixed tumor vaccine concomitant with fractionated radiotherapy for newly diagnosed glioblastoma: Clinical article
-
Muragaki Y, Maruyama T, Iseki H, et al. Phase I/IIa trial of autologous formalin-fixed tumor vaccine concomitant with fractionated radiotherapy for newly diagnosed glioblastoma: clinical article. J Neurosurg. 2011;115:248-55.
-
(2011)
J Neurosurg
, vol.115
, pp. 248-255
-
-
Muragaki, Y.1
Maruyama, T.2
Iseki, H.3
-
51
-
-
0033000339
-
Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans
-
Palu G, Cavaggioni A, Calvi P, et al. Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans. Gene Ther. 1999;6:330-7.
-
(1999)
Gene Ther
, vol.6
, pp. 330-337
-
-
Palu, G.1
Cavaggioni, A.2
Calvi, P.3
-
52
-
-
0023813406
-
Adoptive immunotherapy for recurrent glioblastoma multiforme using lymphokine activated killer cells and recombinant interleukin-2
-
Merchant RE, Grant AJ, Merchant LH, Young HF. Adoptive immunotherapy for recurrent glioblastoma multiforme using lymphokine activated killer cells and recombinant interleukin-2. Cancer. 1988;62:665-71.
-
(1988)
Cancer
, vol.62
, pp. 665-671
-
-
Merchant, R.E.1
Grant, A.J.2
Merchant, L.H.3
Young, H.F.4
-
54
-
-
84937515633
-
Heat shock protein vaccines against glioblastoma: From bench to bedside
-
Ampie L, Choy W, Lamano JB, Fakurnejad S, Bloch O, Parsa AT. Heat shock protein vaccines against glioblastoma: from bench to bedside. J Neurooncol. 2015;123:441-8.
-
(2015)
J Neurooncol
, vol.123
, pp. 441-448
-
-
Ampie, L.1
Choy, W.2
Lamano, J.B.3
Fakurnejad, S.4
Bloch, O.5
Parsa, A.T.6
-
55
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012;366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
-
56
-
-
84879777241
-
Nivolumab plus ipilimumab in advanced melanoma
-
Wolchok JD, Kluger H, Callahan MK, et al. Nivolumab plus ipilimumab in advanced melanoma. N Engl J Med. 2013;369:122-33.
-
(2013)
N Engl J Med
, vol.369
, pp. 122-133
-
-
Wolchok, J.D.1
Kluger, H.2
Callahan, M.K.3
-
57
-
-
84925221855
-
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
-
Ansell SM, Lesokhin AM, Borrello I, et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med. 2015;372:311-9.
-
(2015)
N Engl J Med
, vol.372
, pp. 311-319
-
-
Ansell, S.M.1
Lesokhin, A.M.2
Borrello, I.3
-
58
-
-
84929572937
-
Nivolumab for metastatic renal cell carcinoma: Results of a randomized phase II trial
-
Motzer RJ, Rini BI, McDermott DF, et al. Nivolumab for metastatic renal cell carcinoma: results of a randomized phase II trial. J Clin Oncol. 2015;33:1430-7.
-
(2015)
J Clin Oncol
, vol.33
, pp. 1430-1437
-
-
Motzer, R.J.1
Rini, B.I.2
McDermott, D.F.3
-
59
-
-
84924901863
-
Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): A phase 2, single-arm trial
-
Rizvi NA, Mazières J, Planchard D, et al. Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol. 2015;16:257-65.
-
(2015)
Lancet Oncol
, vol.16
, pp. 257-265
-
-
Rizvi, N.A.1
Mazières, J.2
Planchard, D.3
-
60
-
-
84975739760
-
-
Opdivo (nivolumab) [prescribing information] (Bristol-Myers Squibb Company, 2014)
-
Opdivo (nivolumab) [prescribing information] http://www.opdivo. bmscustomer connect.com/gateway (Bristol-Myers Squibb Company, 2014).
-
-
-
-
61
-
-
84975732891
-
-
Keytruda (pembrolizumab) [prescribing information] (Merck & Co., Inc. 2015)
-
Keytruda (pembrolizumab) [prescribing information] http://www. merck.com/product/usa/pi-circulars/k/keytruda/keytruda-pi.pdf (Merck & Co., Inc. 2015).
-
-
-
-
62
-
-
84937429313
-
A phase 2 study of concurrent radiation therapy, temozolomide, and the histone deacetylase inhibitor valproic acid for patients with glioblastoma
-
Krauze AV, Myrehaug SD, Chang MG, et al. A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma. Int J Radiat Oncol Biol Phys. 2015;92:986-92.
-
(2015)
Int J Radiat Oncol Biol Phys
, vol.92
, pp. 986-992
-
-
Krauze, A.V.1
Myrehaug, S.D.2
Chang, M.G.3
-
63
-
-
84904061991
-
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors
-
Wainwright DA, Chang AL, Dey M, et al. Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors. Clin Cancer Res. 2014;20:5290-301.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 5290-5301
-
-
Wainwright, D.A.1
Chang, A.L.2
Dey, M.3
-
64
-
-
84907498834
-
Blocking immunosuppressive checkpoints for glioma therapy: The more the Merrier!
-
Castro MG, Baker GJ, Lowenstein PR. Blocking immunosuppressive checkpoints for glioma therapy: the more the Merrier! Clin Cancer Res. 2014;20:5147-9.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 5147-5149
-
-
Castro, M.G.1
Baker, G.J.2
Lowenstein, P.R.3
-
65
-
-
0037108683
-
Direct detection and quantitation of a distinct T-cell epitope derived from tumor-specific epithelial cell-associated mucin using human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells
-
Cohen CJ, Hoffmann N, Farago M, Hoogenboom HR, Eisenbach L, Reiter Y. Direct detection and quantitation of a distinct T-cell epitope derived from tumor-specific epithelial cell-associated mucin using human recombinant antibodies endowed with the antigen-specific, major histocompatibility complex-restricted specificity of T cells. Cancer Res. 2002;62:5835-44.
-
(2002)
Cancer Res
, vol.62
, pp. 5835-5844
-
-
Cohen, C.J.1
Hoffmann, N.2
Farago, M.3
Hoogenboom, H.R.4
Eisenbach, L.5
Reiter, Y.6
-
66
-
-
0037047110
-
Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC-restricted T cell receptor-like specificity
-
Denkberg G, Cohen CJ, Lev A, Chames P, Hoogenboom HR, Reiter Y. Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC-restricted T cell receptor-like specificity. Proc Natl Acad Sci. 2002;99:9421-6.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 9421-9426
-
-
Denkberg, G.1
Cohen, C.J.2
Lev, A.3
Chames, P.4
Hoogenboom, H.R.5
Reiter, Y.6
-
67
-
-
0037446653
-
Direct phenotypic analysis of human MHC class i antigen presentation: Visualization, quantitation, and in situ detection of human viral epitopes using peptide-specific, MHC-restricted human recombinant antibodies
-
Cohen CJ, Sarig O, Yamano Y, Tomaru U, Jacobson S, Reiter Y. Direct phenotypic analysis of human MHC class I antigen presentation: visualization, quantitation, and in situ detection of human viral epitopes using peptide-specific, MHC-restricted human recombinant antibodies. J Immunol. 2003;170: 4349-4361.
-
(2003)
J Immunol
, vol.170
, pp. 4349-4361
-
-
Cohen, C.J.1
Sarig, O.2
Yamano, Y.3
Tomaru, U.4
Jacobson, S.5
Reiter, Y.6
-
68
-
-
0037108364
-
Modification of a tumorderived peptide at an HLA-A2 anchor residue can alter the conformation of the MHC-peptide complex: Probing with TCRlike recombinant antibodies
-
Denkberg G, Klechevsky E, Reiter Y. Modification of a tumorderived peptide at an HLA-A2 anchor residue can alter the conformation of the MHC-peptide complex: probing with TCRlike recombinant antibodies. J Immunol. 2002;169:4399-407.
-
(2002)
J Immunol
, vol.169
, pp. 4399-4407
-
-
Denkberg, G.1
Klechevsky, E.2
Reiter, Y.3
-
70
-
-
0035107548
-
Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell in-filtration
-
Yu JS, Wheeler CJ, Zeltzer PM, et al. Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell in-filtration. Cancer Res. 2001;61:842-7.
-
(2001)
Cancer Res
, vol.61
, pp. 842-847
-
-
Yu, J.S.1
Wheeler, C.J.2
Zeltzer, P.M.3
-
71
-
-
23044479028
-
Dendritic cell vaccination in glioblastoma patients induces systemic andintracranial T-cell responses modulated by the local central nervous system tumor microenvironment
-
Liau LM, Prins RM, Kiertscher SM, et al. Dendritic cell vaccination in glioblastoma patients induces systemic andintracranial T-cell responses modulated by the local central nervous system tumor microenvironment. Clin Cancer Res. 2005;11:5515-25.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5515-5525
-
-
Liau, L.M.1
Prins, R.M.2
Kiertscher, S.M.3
-
72
-
-
78149254368
-
Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma
-
Sampson JH, Heimberger AB, Archer GE, et al. Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma. J Clin Oncol. 2010;28:4722-9.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4722-4729
-
-
Sampson, J.H.1
Heimberger, A.B.2
Archer, G.E.3
-
73
-
-
0034784610
-
Preliminary results of active specific immunization with modified tumor cell vaccine in glioblastoma multiforme
-
Schneider T, Gerhards R, Kirches E, Firsching R. Preliminary results of active specific immunization with modified tumor cell vaccine in glioblastoma multiforme. J Neuro-Oncol. 2001;53:39-46.
-
(2001)
J Neuro-Oncol
, vol.53
, pp. 39-46
-
-
Schneider, T.1
Gerhards, R.2
Kirches, E.3
Firsching, R.4
-
74
-
-
16544392098
-
Antitumor vaccination of patients with glioblastoma multiforme: A pilot study to assess feasibility, safety, and clinical benefit
-
Steiner HH, Bonsanto MM, Beckhove P, et al. Antitumor vaccination of patients with glioblastoma multiforme: a pilot study to assess feasibility, safety, and clinical benefit. J Clin Oncol. 2004;22:4272-81.
-
(2004)
J Clin Oncol
, vol.22
, pp. 4272-4281
-
-
Steiner, H.H.1
Bonsanto, M.M.2
Beckhove, P.3
-
75
-
-
34347238993
-
Clinical trial of autologous formalin-fixed tumor vaccine for Glioblastoma multiforme patients
-
Ishikawa E, Tsuboi K, Yamamoto T, et al. Clinical trial of autologous formalin-fixed tumor vaccine for Glioblastoma multiforme patients. Cancer Sci. 2007;98:1226-33.
-
(2007)
Cancer Sci
, vol.98
, pp. 1226-1233
-
-
Ishikawa, E.1
Tsuboi, K.2
Yamamoto, T.3
-
76
-
-
79951602633
-
Targeted therapy for highgrade glioma with the TGF-beta2 inhibitor trabedersen: Results of a randomized and controlled phase IIb study
-
Bogdahn U, Hau P, Stockhammer G, et al. Targeted therapy for highgrade glioma with the TGF-beta2 inhibitor trabedersen: results of a randomized and controlled phase IIb study. Neuro-Oncol. 2011;13:132-42.
-
(2011)
Neuro-Oncol
, vol.13
, pp. 132-142
-
-
Bogdahn, U.1
Hau, P.2
Stockhammer, G.3
-
77
-
-
0026570661
-
Treatment of recurrent malignant glioma by repeated intracerebral injections of human recombinant interleukin-2 alone or in combination with systemic interferon-?. Results of a phase i clinical trial
-
Merchant RE, McVicar DW, Merchant LH, Young HF. Treatment of recurrent malignant glioma by repeated intracerebral injections of human recombinant interleukin-2 alone or in combination with systemic interferon-? . Results of a phase I clinical trial. J Neuro-Oncol. 1992;12:75-83.
-
(1992)
J Neuro-Oncol
, vol.12
, pp. 75-83
-
-
Merchant, R.E.1
McVicar, D.W.2
Merchant, L.H.3
Young, H.F.4
-
78
-
-
0024510754
-
Intratumoral LAK cell and interleukin-2 therapy of human gliomas
-
Barba D, Saris SC, Holder C, Rosenberg SA, Oldfield EH. Intratumoral LAK cell and interleukin-2 therapy of human gliomas. J Neurosurgery. 1989;70:175-82.
-
(1989)
J Neurosurgery
, vol.70
, pp. 175-182
-
-
Barba, D.1
Saris, S.C.2
Holder, C.3
Rosenberg, S.A.4
Oldfield, E.H.5
-
79
-
-
30644457691
-
Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: Biological and clinical results
-
Colombo F, Barzon L, Franchin E, et al. Combined HSV-TK/IL-2 gene therapy in patients with recurrent glioblastoma multiforme: biological and clinical results. Cancer Gene Ther. 2005;12: 835-48.
-
(2005)
Cancer Gene Ther
, vol.12
, pp. 835-848
-
-
Colombo, F.1
Barzon, L.2
Franchin, E.3
-
80
-
-
0028275672
-
Randomised, controlled study of intratumoral recombinant ?-interferon treatment in newly diagnosed glioblastoma
-
Farkkila M, Jaaskelainen J, Kallio M, et al. Randomised, controlled study of intratumoral recombinant ?-interferon treatment in newly diagnosed glioblastoma. Br J Cancer. 1994;70:138-41.
-
(1994)
Br J Cancer
, vol.70
, pp. 138-141
-
-
Farkkila, M.1
Jaaskelainen, J.2
Kallio, M.3
-
81
-
-
33748580294
-
Maintenance treatment with interferon-gamma and low-dose cyclophosphamide for pediatric high-grade glioma
-
Wolff JE, Wagner S, Reinert C, et al. Maintenance treatment with interferon-gamma and low-dose cyclophosphamide for pediatric high-grade glioma. J Neuro-Oncol. 2006;79:315-21.
-
(2006)
J Neuro-Oncol
, vol.79
, pp. 315-321
-
-
Wolff, J.E.1
Wagner, S.2
Reinert, C.3
-
82
-
-
0025897346
-
Recombinant interferon beta: A phase I-II trial in children with recurrent brain tumors
-
Allen J, Packer R, Bleyer A, Zeltzer P, Prados M, Nirenberg A. Recombinant interferon beta: a phase I-II trial in children with recurrent brain tumors. J Clin Oncol. 1991;9:783-8.
-
(1991)
J Clin Oncol
, vol.9
, pp. 783-788
-
-
Allen, J.1
Packer, R.2
Bleyer, A.3
Zeltzer, P.4
Prados, M.5
Nirenberg, A.6
-
83
-
-
0025055369
-
Intratumor administration of beta-interferon in recurrent malignant gliomas. A Phase i clinical and laboratory study
-
Fetell MR, Housepian EM, Oster MW, et al. Intratumor administration of beta-interferon in recurrent malignant gliomas. A Phase I clinical and laboratory study. Cancer. 1990;65:78-83.
-
(1990)
Cancer
, vol.65
, pp. 78-83
-
-
Fetell, M.R.1
Housepian, E.M.2
Oster, M.W.3
-
84
-
-
0024347330
-
Systemic beta-interferon therapy for recurrent gliomas: A brief report
-
Mahaley MS, Dropcho EJ, Bertsch L, Tirey T, Gillespie GY. Systemic beta-interferon therapy for recurrent gliomas: a brief report. J Neurosurgery. 1989;71:639-41.
-
(1989)
J Neurosurgery
, vol.71
, pp. 639-641
-
-
Mahaley, M.S.1
Dropcho, E.J.2
Bertsch, L.3
Tirey, T.4
Gillespie, G.Y.5
-
85
-
-
0028929258
-
Phase II evaluation of recombinant interferon alpha and BCNU in recurrent glioma
-
Buckner JC, Brown LD, Kugler JW, et al. Phase II evaluation of recombinant interferon alpha and BCNU in recurrent glioma. J Neurosurgery. 1995;82:430-5.
-
(1995)
J Neurosurgery
, vol.82
, pp. 430-435
-
-
Buckner, J.C.1
Brown, L.D.2
Kugler, J.W.3
-
86
-
-
0035878917
-
A Phase III study of radiation therapy plus carmustine with or without recombinant interferon-? in the treatment of patients with newly diagnosed high-grade glioma
-
Buckner JC, Schomberg PJ, McGinnis WL, et al. A Phase III study of radiation therapy plus carmustine with or without recombinant interferon-? in the treatment of patients with newly diagnosed high-grade glioma. Cancer. 2001;92:420-33.
-
(2001)
Cancer
, vol.92
, pp. 420-433
-
-
Buckner, J.C.1
Schomberg, P.J.2
McGinnis, W.L.3
-
87
-
-
56249111936
-
Phase i analysis of BCNU-impregnated biodegradable polymer wafers followed by systemic interferon alfa-2b in adults with recurrent glioblastoma multiforme
-
Olson JJ, McKenzie E, Skurski-Martin M, Zhang Z, Brat D, Phuphanich S. Phase I analysis of BCNU-impregnated biodegradable polymer wafers followed by systemic interferon alfa-2b in adults with recurrent glioblastoma multiforme. J Neuro-Oncol. 2008;90:293-9.
-
(2008)
J Neuro-Oncol
, vol.90
, pp. 293-299
-
-
Olson, J.J.1
McKenzie, E.2
Skurski-Martin, M.3
Zhang, Z.4
Brat, D.5
Phuphanich, S.6
-
88
-
-
40149090821
-
Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas
-
Okada H, Lieberman FS, Walter KA, et al. Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomas. J Transl Med. 2007;5:67.
-
(2007)
J Transl Med
, vol.5
, pp. 67
-
-
Okada, H.1
Lieberman, F.S.2
Walter, K.A.3
-
89
-
-
0034047780
-
Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with highgrade glioma
-
Rand RW, Kreitman RJ, Patronas N, Varricchio F, Pastan I, Puri RK. Intratumoral administration of recombinant circularly permuted interleukin-4-Pseudomonas exotoxin in patients with highgrade glioma. Clin Cancer Res. 2000;6:2157-65.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2157-2165
-
-
Rand, R.W.1
Kreitman, R.J.2
Patronas, N.3
Varricchio, F.4
Pastan, I.5
Puri, R.K.6
-
90
-
-
7444220033
-
Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12
-
Kikuchi T, Akasaki Y, Abe T, et al. Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12. J Immunother. 2004;27:452-9.
-
(2004)
J Immunother
, vol.27
, pp. 452-459
-
-
Kikuchi, T.1
Akasaki, Y.2
Abe, T.3
-
91
-
-
0022641036
-
Interleukin-2 or autologous lymphokine-activated killer cell treatment of malignant glioma: Phase i trial
-
Jacobs SK, Wilson DJ, Kornblith PL, Grimm EA. Interleukin-2 or autologous lymphokine-activated killer cell treatment of malignant glioma: phase I trial. Cancer Res. 1986;46:2101-4.
-
(1986)
Cancer Res
, vol.46
, pp. 2101-2104
-
-
Jacobs, S.K.1
Wilson, D.J.2
Kornblith, P.L.3
Grimm, E.A.4
-
92
-
-
0025974603
-
Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy
-
Lillehei KO, Mitchell DH, Johnson SD, McCleary EL, Kruse CA. Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy. Neurosurgery. 1991;28:16-23.
-
(1991)
Neurosurgery
, vol.28
, pp. 16-23
-
-
Lillehei, K.O.1
Mitchell, D.H.2
Johnson, S.D.3
McCleary, E.L.4
Kruse, C.A.5
-
93
-
-
0029145309
-
Improved long term survival after intracavitary interleukin-2 and lymphokineactivated killer cells for adults with recurrent malignant glioma
-
Hayes RL, Koslow M, Hiesiger EM, et al. Improved long term survival after intracavitary interleukin-2 and lymphokineactivated killer cells for adults with recurrent malignant glioma. Cancer. 1995;76:840-52.
-
(1995)
Cancer
, vol.76
, pp. 840-852
-
-
Hayes, R.L.1
Koslow, M.2
Hiesiger, E.M.3
-
94
-
-
4344689067
-
Intracavitary placement of autologous lymphokine-activated killer (LAK) cells after resection of recurrent glioblastoma
-
Dillman RO, Duma CM, Schiltz PM, et al. Intracavitary placement of autologous lymphokine-activated killer (LAK) cells after resection of recurrent glioblastoma. J Immunother. 2004;27: 398-404.
-
(2004)
J Immunother
, vol.27
, pp. 398-404
-
-
Dillman, R.O.1
Duma, C.M.2
Schiltz, P.M.3
-
95
-
-
0032999584
-
Reduction of end-stage malignant glioma by injection with autologous cytotoxic T lymphocytes
-
Tsurushima H, Liu SQ, Tuboi K, et al. Reduction of end-stage malignant glioma by injection with autologous cytotoxic T lymphocytes. Jap J Cancer Res. 1999;90:536-45.
-
(1999)
Jap J Cancer Res
, vol.90
, pp. 536-545
-
-
Tsurushima, H.1
Liu, S.Q.2
Tuboi, K.3
-
96
-
-
0034044202
-
T cell adoptive immunotherapy of newly diagnosed gliomas
-
Plautz GE, Miller DW, Barnett GH, et al. T cell adoptive immunotherapy of newly diagnosed gliomas. Clin Cancer Res. 2000;6:2209-18.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 2209-2218
-
-
Plautz, G.E.1
Miller, D.W.2
Barnett, G.H.3
-
97
-
-
84855604775
-
Challenges in Immunotherapy Presented by the Glioblastoma Multiforme Microenvironment
-
Jackson C, Ruzevick J, Phallen J, Belcaid Z, Lim M. Challenges in Immunotherapy Presented by the Glioblastoma Multiforme Microenvironment. Clin Dev Immunol. 2011;2011:732413, doi: 10.1155/2011/732413. Epub 2011 Dec 10.
-
(2011)
Clin Dev Immunol
, vol.2011
, pp. 732413
-
-
Jackson, C.1
Ruzevick, J.2
Phallen, J.3
Belcaid, Z.4
Lim, M.5
-
98
-
-
84929645757
-
Stereotactic radiosurgery and immunotherapy for metastatic spinal melanoma
-
Caruso JP, Cohen-Inbar O, Bilsky MH, Gerszten PC, Sheehan JP. Stereotactic radiosurgery and immunotherapy for metastatic spinal melanoma. Neurosurg Focus. 2015;38:E6.
-
(2015)
Neurosurg Focus
, vol.38
, pp. E6
-
-
Caruso, J.P.1
Cohen-Inbar, O.2
Bilsky, M.H.3
Gerszten, P.C.4
Sheehan, J.P.5
|