Decreased rate of infection in glioblastoma patients with allelic loss of chromosome 10q

Journal of Neuro-Oncology

Volumn 93, Issue 1, 2009, Pages 115-120

  Aghi, Manish K ^a   Batchelor, Tracy T ^b,c   Louis, David N ^c   Barker, Fred G ^b,c   Curry, William T ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Chromosome 10q; Glioblastoma; Helper T cells; Infection

Indexed keywords

ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; CD274 ANTIGEN; DEXAMETHASONE; DNA; LYMPHOCYTE ANTIGEN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BACTERIAL INFECTION; CANCER RADIOTHERAPY; CANCER SURVIVAL; CELLULAR IMMUNITY; CHROMOSOME 10Q; CHROMOSOME LOSS; CONTROLLED STUDY; CRANIOTOMY; CYTOKINE RELEASE; GENE DISRUPTION; GENE MUTATION; GLIOBLASTOMA; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE SYSTEM; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; MEDICAL RESEARCH; MICROSATELLITE MARKER; MORBIDITY; MORTALITY; PNEUMONIA; PROTEIN EXPRESSION; SEPSIS; TH2 CELL; TUMOR IMMUNITY; URINARY TRACT INFECTION; WOUND INFECTION;

BACTERIAL INFECTIONS; BRAIN NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 10; GLIOBLASTOMA; HUMANS; KAPLAN-MEIERS ESTIMATE; LOSS OF HETEROZYGOSITY; MIDDLE AGED; RETROSPECTIVE STUDIES;

EID: 65649149438     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-009-9826-3     Document Type: Article

References (28)

1. Dabholkar MD, Berger MS, Vionnet JA, Overton L, Thompson C, Bostick-Bruton F, Yu JJ, Silber JR, Reed E (1996) Comparative analyses of relative ERCC3 and ERCC6 mRNA levels in gliomas and adjacent non-neoplastic brain. Mol Carcinog 17:1-7. doi: 10.1002/ (SICI)1098-2744(199609)17:1<1::AID-MC1>3.0.CO;2-M
2. Suzuki T, Maruno M, Wada K, Kagawa N, Fujimoto Y, Hashimoto N, Izumoto S, Yoshimine T (2004) Genetic analysis of human glioblastomas using a genomic microarray system. Brain Tumor Pathol 21:27-34. doi: 10.1007/ BF02482174
3. Choe G, Horvath S, Cloughesy TF, Crosby K, Seligson D, Palotie A, Inge L, Smith BL, Sawyers CL, Mischel PS (2003) Analysis of the phosphatidylinositol 3′-kinase signaling pathway in glioblastoma patients in vivo. Cancer Res 63:2742-2746
4. Ermoian RP, Furniss CS, Lamborn KR, Basila D, Berger MS, Gottschalk AR, Nicholas MK, Stokoe D, Haas-Kogan DA (2002) Dysregulation of PTEN and protein kinase B is associated with glioma histology and patient survival. Clin Cancer Res 8:1100-1106
5. Smith JS, Tachibana I, Passe SM, Huntley BK, Borell TJ, Iturria N, O'Fallon JR, Schaefer PL, Scheithauer BW, James CD, Buckner JC, Jenkins RB (2001) PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme. J Natl Cancer Inst 93:1246-1256. doi: 10.1093/jnci/93.16.1246
6. Daido S, Takao S, Tamiya T, Ono Y, Terada K, Ito S, Ouchida M, Date I, Ohmoto T, Shimizu K (2004) Loss of heterozygosity on chromosome 10q associated with malignancy and prognosis in astrocytic tumors, and discovery of novel loss regions. Oncol Rep 12:789-795
7. Hao C, Parney IF, Roa WH, Turner J, Petruk KC, Ramsay DA (2002) Cytokine and cytokine receptor mRNA expression in human glioblastomas: Evidence of Th1, Th2 and Th3 cytokine dysregulation. Acta Neuropathol 103:171-178. doi: 10.1007/s004010100448
8. Morford LA, Dix AR, Brooks WH, Roszman TL (1999) Apoptotic elimination of peripheral T lymphocytes in patients with primary intracranial tumors. J Neurosurg 91:935-946
9. Mollenhauer J, Herbertz S, Holmskov U, Tolnay M, Krebs I, Merlo A, Schroder HD, Maier D, Breitling F, Wiemann S, Grone HJ, Poustka A (2000) DMBT1 encodes a protein involved in the immune defense and in epithelial differentiation and is highly unstable in cancer. Cancer Res 60:1704-1710
10. Parsa AT, Waldron JS, Panner A, Crane CA, Parney IF, Barry JJ, Cachola KE, Murray JC, Tihan T, Jensen MC, Mischel PS, Stokoe D, Pieper RO (2007) Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma. Nat Med 13:84-88. doi: 10.1038/nm1517
11. Moody JL, Jirik FR (2004) Compound heterozygosity for Pten and SHIP augments T-dependent humoral immune responses and cytokine production by CD(4 +) T cells. Immunology 112:404-412. doi: 10.1111/ j.1365-2567.2004.01901.x
12. Suzuki A, Yamaguchi MT, Ohteki T, Sasaki T, Kaisho T, Kimura Y, Yoshida R, Wakeham A, Higuchi T, Fukumoto M, Tsubata T, Ohashi PS, Koyasu S, Penninger JM, Nakano T, Mak TW (2001) T cell-specific loss of Pten leads to defects in central and peripheral tolerance. Immunity 14:523-534. doi: 10.1016/S1074-7613(01)00134-0
13. Louis DN, von Deimling A, Seizinger BR (1992) A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens. Am J Pathol 141:777-782
14. Batchelor TT, Betensky RA, Esposito JM, Pham LD, Dorfman MV, Piscatelli N, Jhung S, Rhee D, Louis DN (2004) Age-dependent prognostic effects of genetic alterations in glioblastoma. Clin Cancer Res 10:228-233. doi: 10.1158/1078-0432.CCR-0841-3
15. Hughes MA, Parisi M, Grossman S, Kleinberg L (2005) Primary brain tumors treated with steroids and radiotherapy: Low CD4 counts and risk of infection. Int J Radiat Oncol Biol Phys 62:1423-1426. doi: 10.1016/ j.ijrobp.2004.12.085
16. Zentner J, Gilsbach J, Daschner F (1987) Incidence of wound infection in patients undergoing craniotomy: Influence of type of shaving. Acta Neurochir (Wien) 86:79-82. doi: 10.1007/BF01402288
17. Teng DH, Hu R, Lin H, Davis T, Iliev D, Frye C, Swedlund B, Hansen KL, Vinson VL, Gumpper KL, Ellis L, El-Naggar A, Frazier M, Jasser S, Langford LA, Lee J, Mills GB, Pershouse MA, Pollack RE, Tornos C, Troncoso P, Yung WK, Fujii G, Berson A, Steck PA et al (1997) MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res 57:5221-5225
18. Sasaki H, Betensky RA, Cairncross JG, Louis DN (2002) DMBT1 polymorphisms: Relationship to malignant glioma tumorigenesis. Cancer Res 62:1790-1796
19. Kumar R, Kamdar D, Madden L, Hills C, Crooks D, O'Brien D, Greenman J (2006) Th1/Th2 cytokine imbalance in meningioma, anaplastic astrocytoma and glioblastoma multiforme patients. Oncol Rep 15:1513-1516
20. Zisakis A, Piperi C, Themistocleous MS, Korkolopoulou P, Boviatsis EI, Sakas DE, Patsouris E, Lea RW, Kalofoutis A (2007) Comparative analysis of peripheral and localised cytokine secretion in glioblastoma patients. Cytokine 39:99-105. doi: 10.1016/j.cyto.2007.05.012
21. Fecci PE, Mitchell DA, Whitesides JF, Xie W, Friedman AH, Archer GE, Herndon JE II, Bigner DD, Dranoff G, Sampson JH (2006) Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma. Cancer Res 66:3294-3302. doi: 10.1158/0008-5472.CAN-05-3773
22. Hong S, Qian J, Yang J, Li H, Kwak LW, Yi Q (2008) Roles of idiotype-specific t cells in myeloma cell growth and survival: Th1 and CTL cells are tumoricidal while Th2 cells promote tumor growth. Cancer Res 68:8456-8464. doi: 10.1158/0008-5472.CAN-08-2213
23. Bowles AP Jr, Perkins E (1999) Long-term remission of malignant brain tumors after intracranial infection: A report of four cases. Neurosurgery 44:636-642. doi: 10.1097/00006123-199903000-00110
24. Borrello I, Sotomayor E, Grossman SA (1997) Postoperative infections may impart a survival advantage in high-grade astrocytomas. American Society of Clinical Oncology (ASCO) 33rd Annual Meeting, Denver, CO
25. Ruckdeschel JC, Codish SD, Stranahan A, McKneally MF (1972) Postoperative empyema improves survival in lung cancer. Documentation and analysis of a natural experiment. N Engl J Med 287:1013-1017
26. Cady B, Cliffton EE (1967) Empyema and survival following surgery for bronchogenic carcinoma. J Thorac Cardiovasc Surg 53:102-108
27. Mariani CL, Rajon D, Bova FJ, Streit WJ (2007) Nonspecific immunotherapy with intratumoral lipopolysaccharide and zymosan A but not GM-CSF leads to an effective anti-tumor response in subcutaneous RG-2 gliomas. J Neurooncol 85:231-240. doi: 10.1007/s11060-007-9415-2
28. Chicoine MR, Won EK, Zahner MC (2001) Intratumoral injection of lipopolysaccharide causes regression of subcutaneously implanted mouse glioblastoma multiforme. Neurosurgery 48:607-614. doi: 10.1097/ 00006123-200103000-00032