Impact of Single Nucleotide Polymorphisms of Base Excision Repair Genes on DNA Damage and Efficiency of DNA Repair in Recurrent Depression Disorder

Molecular Neurobiology

Volumn 54, Issue 6, 2017, Pages 4150-4159

  Czarny, Piotr ^a,b   Kwiatkowski, Dominik ^a   Toma, Monika ^a   Kubiak, Joanna ^a   Sliwinska, Agnieszka ^b   Talarowska, Monika ^b   Szemraj, Janusz ^b   Maes, Michael ^c,d,e   Galecki, Piotr ^b   Sliwinski, Tomasz ^a  

^a UNIVERSITY OF LODZ   (Poland)

^b MEDICAL UNIVERSITY OF LODZ   (Poland)

^c DEAKIN UNIVERSITY   (Australia)

^d CHULALONGKORN UNIVERSITY   (Thailand)

^e STATE UNIVERSITY OF LONDRINA   (Brazil)

Author keywords

Base excision repair; DNA damage; DNA repair; Oxidative stress; Recurrent depression disorder; Single nucleotide polymorphism

Indexed keywords

DNA; DNA GLYCOSYLTRANSFERASE; OXOGUANINE GLYCOSYLASE 1, HUMAN;

ADULT; ARTICLE; CLINICAL ARTICLE; COMET ASSAY; CONTROLLED STUDY; DEPRESSION; DNA DAMAGE; DNA REPAIR; EXCISION REPAIR; GENETIC REGULATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; MOLECULAR PATHOLOGY; MOLECULAR PROBE; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; RECURRENT DISEASE; SINGLE NUCLEOTIDE POLYMORPHISM; ALLELE; CASE CONTROL STUDY; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; OXIDATION REDUCTION REACTION; RISK FACTOR;

ALLELES; CASE-CONTROL STUDIES; DEPRESSION; DNA DAMAGE; DNA GLYCOSYLASES; DNA REPAIR; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MIDDLE AGED; OXIDATION-REDUCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84975229544     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-9971-6     Document Type: Article

References (35)

1. Pasco JA, Nicholson GC, Williams LJ, Jacka FN, Henry MJ, Kotowicz MA, Schneider HG, Leonard BE, Berk M (2010) Association of high-sensitivity C-reactive protein with de novo major depression. Br J Psychiatry 197:372–377
2. Gardner A, Boles RG (2011) Beyond the serotonin hypothesis: mitochondria, inflammation and neurodegeneration in major depression and affective spectrum disorders. Prog Neuropsychopharmacol Biol Psychiatry 35:730–743
3. Maes M, Bosmans E, Meltzer HY, Scharpé S, Suy E (1993) Interleukin-1 beta: a putative mediator of HPA axis hyperactivity in major depression? Am J Psychiatry 150:1189–1193
4. Rawdin BJ, Mellon SH, Dhabhar FS, Epel ES, Puterman E, Su Y, Burke HM, Reus VI, Rosser R, Hamilton SP, Nelson JC, Wolkowitz OM (2013) Dysregulated relationship of inflammation and oxidative stress in major depression. Brain Brain Behav Immun 31:143–152
5. Leemans JC, Cassel SL, Sutterwala FS (2011) Sensing damage by the NLRP3 inflammasome. Immunol Rev 243:152–162
6. Alcocer-Gómez E, de Miguel M, Casas-Barquero N, Núñez-Vasco J, Sánchez-Alcazar JA, Fernández-Rodríguez A, Cordero MD (2014) NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder. Brain Brain Behav Immun 36:111–117
7. Licandro G, Ling Khor H, Beretta O, Lai J, Derks H, Laudisi F, Conforti-Andreoni C, Liang Qian H, Teng GG, Ricciardi-Castagnoli P, Mortellaro A (2013) The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells. Eur J Immunol 43:2126–2137
8. Anderson G, Maes M (2014) Oxidative/nitrosative stress and immuno-inflammatory pathways in depression: treatment implications. Curr Pharm Des 20:3812–3847
9. Irie M, Asami S, Nagata S, Ikeda M, Miyata M, Kasai H (2001) Psychosocial factors as a potential trigger of oxidative DNA damage in human leukocytes. Jpn J Cancer Res 92:367–376
10. Irie M, Asami S, Ikeda M, Kasai H (2003) Depressive state relates to female oxidative DNA damage via neutrophil activation. Biochem Biophys Res Commun 311:1014–1018
11. Forlenza MJ, Miller GE (2006) Increased serum levels of 8-hydroxy-2′-deoxyguanosine in clinical depression. Psychosom Med 68:1–7
12. Maes M, Mihaylova I, Kubera M, Uytterhoeven M, Vrydags N, Bosmans E (2009) Increased 8-hydroxy-deoxyguanosine, a marker of oxidative damage to DNA, in major depression and myalgic encephalomyelitis/chronic fatigue syndrome. Neuro Endocrinol Lett 30:715–722
13. Wei YC, Zhou FL, He DL, Bai JR, Ding H, Wang XY, Nan KJ (2009) Oxidative stress in depressive patients with gastric adenocarcinoma. Int J Neuropsychopharmacol 12:1089–1096
14. Kupper N, Gidron Y, Winter J, Denollet J (2009) Association between type D personality, depression, and oxidative stress in patients with chronic heart failure. Psychosom Med 71:973–980
15. Yi S, Nanri A, Matsushita Y, Kasai H, Kawai K, Mizoue T (2012) Depressive symptoms and oxidative DNA damage in Japanese municipal employees. Psychiatry Res 200:318–322
16. Czarny P, Kwiatkowski D, Kacperska D, Kawczyńska D, Talarowska M, Orzechowska A, Bielecka-Kowalska A, Szemraj J, Gałecki P, Śliwiński T (2015) Elevated level of DNA damage and impaired repair of oxidative DNA damage in patients with recurrent depressive disorder. Med Sci Monit 21:412–418
17. Czarny P, Kwiatkowski D, Galecki P, Talarowska M, Orzechowska A, Bobinska K, Bielecka-Kowalska A, Szemraj J, Maes M, Su KP, Sliwinski T (2015) Association between single nucleotide polymorphisms of MUTYH, hOGG1 and NEIL1 genes, and depression. J Affect Disord 184:90–96
18. Erčulj N, Zadel M, Dolžan V (2010) Genetic polymorphisms in base excision repair in healthy slovenian population and their influence on DNA damage. Acta Chim Slov 57:182–188
19. Zielinska A, Davies OT, Meldrum RA, Hodges NJ (2011) Direct visualization of repair of oxidative damage by OGG1 in the nuclei of live cells. J Biochem Mol Toxicol 25:1–7
20. World Health Organization (1992) ICD-10 Classification of Mental and Behavioural Disorders. WHO, Geneva
21. Patten SB (1997) Performance of the Composite International Diagnostic Interview Short Form for major depression in community and clinical samples. Chronic Dis Can 3:18–24
22. Singh NP, McCoy MT, Tice RR, Schneider EL (1988) A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184–191
23. Klaude M, Eriksson S, Nygren J, Ahnström G (1996) The comet assay: mechanisms and technical considerations. Mutat Res 12:89–96
24. Blasiak J, Gloc E, Drzewoski J, Wozniak K, Zadrozny M, Skórski T, Pertynski T (2003) Free radicals scavengers can differentially modulate the genotoxicity of amsacrine in normal and cancer cells. Mutat Res 535:25–34
25. Blasiak J, Synowiec E, Tarnawska J, Czarny P, Poplawski T, Reiter RJ (2012) Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair. Mol Biol Rep 39:7487–7496
26. Bjorâs M, Luna L, Johnsen B, Hoff E, Haug T, Rognes T, Seeberg E (1997) Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sites. EMBO J 16:6314–6322
27. Boiteux S, Radicella JP (1999) Base excision repair of 8-hydroxyguanine protects DNA from endogenous oxidative stress. Biochimie 81:59–67
28. Dizdaroglu M, Laval J, Boiteux S (1993) Substrate specificity of the Escherichia coli endonuclease III: excision of thymine- and cytosine-derived lesions in DNA produced by radiation-generated free radicals. Biochemistry 32:12105–12111
29. Hatahet Z, Kow YW, Purmal AA, Cunningham RP, Wallace SS (1994) New substrates for old enzymes. 5-Hydroxy-2′-deoxycytidine and 5-hydroxy-2′-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2′-deoxyuridine is a substrate for uracil DNA N-glycosylase. J Biol Chem 269:18814–18820
30. Lu J, Zhang S, Chen D, Wang H, Wu W, Wang X, Lei Y, Wang J, Qian J, Fan W, Hu Z, Jin L, Shen H, Huang W, Wei Q, Lu D (2009) Functional characterization of a promoter polymorphism in APE1/Ref-1 that contributes to reduced lung cancer susceptibility. FASEB J 23:3459–3469
31. Lo YL, Jou YS, Hsiao CF, Chang GC, Tsai YH, Su WC, Chen KY, Chen YM, Huang MS, Hu CY, Chen CJ, Hsiung CA (2009) A polymorphism in the APE1 gene promoter is associated with lung cancer risk. Cancer Epidemiol Biomarkers Prev 18:223–229
32. Synowiec E, Stefanska J, Morawiec Z, Blasiak J, Wozniak K (2008) Association between DNA damage, DNA repair genes variability and clinical characteristics in breast cancer patients. Mutat Res 648:65–72
33. Synowiec E, Krupa R, Morawiec Z, Wasylecka M, Dziki L, Morawiec J, Blasiak J, Wozniak K (2010) Efficacy of DNA double-strand breaks repair in breast cancer is decreased in carriers of the variant allele of the UBC9 gene c.73G>A polymorphism. Mutat Res 10:31–38
34. Maes M, Galecki P, Chang YS, Berk M (2011) A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness. Prog Neuropsychopharmacol Biol Psychiatry 35:676–692
35. Moylan S, Berk M, Dean OM, Samuni Y, Williams LJ, O'Neil A, Hayley AC, Pasco JA, Anderson G, Jacka FN, Maes M (2014) Oxidative & nitrosative stress in depression: why so much stress? Neurosci Biobehav Rev 45:46–62