-
1
-
-
84255183707
-
The search for effective therapy for sepsis: Back to the drawing board?
-
D.C. Angus The search for effective therapy for sepsis: back to the drawing board? JAMA 306 2011 2614 2615
-
(2011)
JAMA
, vol.306
, pp. 2614-2615
-
-
Angus, D.C.1
-
2
-
-
77953462161
-
Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection
-
M.T. Baldridge, K.Y. King, N.C. Boles, D.C. Weksberg, and M.A. Goodell Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection Nature 465 2010 793 797
-
(2010)
Nature
, vol.465
, pp. 793-797
-
-
Baldridge, M.T.1
King, K.Y.2
Boles, N.C.3
Weksberg, D.C.4
Goodell, M.A.5
-
3
-
-
0033952703
-
Tlr4: Central component of the sole mammalian LPS sensor
-
B. Beutler Tlr4: central component of the sole mammalian LPS sensor Curr. Opin. Immunol. 12 2000 20 26
-
(2000)
Curr. Opin. Immunol.
, vol.12
, pp. 20-26
-
-
Beutler, B.1
-
4
-
-
84907333314
-
Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis
-
S. Boettcher, R.C. Gerosa, R. Radpour, J. Bauer, F. Ampenberger, M. Heikenwalder, M. Kopf, and M.G. Manz Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis Blood 124 2014 1393 1403
-
(2014)
Blood
, vol.124
, pp. 1393-1403
-
-
Boettcher, S.1
Gerosa, R.C.2
Radpour, R.3
Bauer, J.4
Ampenberger, F.5
Heikenwalder, M.6
Kopf, M.7
Manz, M.G.8
-
5
-
-
84875262757
-
The inflammatory response in sepsis
-
M. Bosmann, and P.A. Ward The inflammatory response in sepsis Trends Immunol. 34 2013 129 136
-
(2013)
Trends Immunol.
, vol.34
, pp. 129-136
-
-
Bosmann, M.1
Ward, P.A.2
-
6
-
-
20444469154
-
Roles of Sca-1 in hematopoietic stem/progenitor cell function
-
S.B. Bradfute, T.A. Graubert, and M.A. Goodell Roles of Sca-1 in hematopoietic stem/progenitor cell function Exp. Hematol. 33 2005 836 843
-
(2005)
Exp. Hematol.
, vol.33
, pp. 836-843
-
-
Bradfute, S.B.1
Graubert, T.A.2
Goodell, M.A.3
-
7
-
-
79952378225
-
Epigenetic regulation of immune cell functions during post-septic immunosuppression
-
W.F. Carson, K.A. Cavassani, Y. Dou, and S.L. Kunkel Epigenetic regulation of immune cell functions during post-septic immunosuppression Epigenetics 6 2011 273 283
-
(2011)
Epigenetics
, vol.6
, pp. 273-283
-
-
Carson, W.F.1
Cavassani, K.A.2
Dou, Y.3
Kunkel, S.L.4
-
8
-
-
84555207349
-
Dnmt3a is essential for hematopoietic stem cell differentiation
-
G.A. Challen, D. Sun, M. Jeong, M. Luo, J. Jelinek, J.S. Berg, C. Bock, A. Vasanthakumar, H. Gu, Y. Xi, and et al. Dnmt3a is essential for hematopoietic stem cell differentiation Nat. Genet. 44 2012 23 31
-
(2012)
Nat. Genet.
, vol.44
, pp. 23-31
-
-
Challen, G.A.1
Sun, D.2
Jeong, M.3
Luo, M.4
Jelinek, J.5
Berg, J.S.6
Bock, C.7
Vasanthakumar, A.8
Gu, H.9
Xi, Y.10
-
9
-
-
79955530513
-
Chronic exposure to a TLR ligand injures hematopoietic stem cells
-
B.L. Esplin, T. Shimazu, R.S. Welner, K.P. Garrett, L. Nie, Q. Zhang, M.B. Humphrey, Q. Yang, L.A. Borghesi, and P.W. Kincade Chronic exposure to a TLR ligand injures hematopoietic stem cells J. Immunol. 186 2011 5367 5375
-
(2011)
J. Immunol.
, vol.186
, pp. 5367-5375
-
-
Esplin, B.L.1
Shimazu, T.2
Welner, R.S.3
Garrett, K.P.4
Nie, L.5
Zhang, Q.6
Humphrey, M.B.7
Yang, Q.8
Borghesi, L.A.9
Kincade, P.W.10
-
10
-
-
66149115277
-
IFNalpha activates dormant haematopoietic stem cells in vivo
-
M.A. Essers, S. Offner, W.E. Blanco-Bose, Z. Waibler, U. Kalinke, M.A. Duchosal, and A. Trumpp IFNalpha activates dormant haematopoietic stem cells in vivo Nature 458 2009 904 908
-
(2009)
Nature
, vol.458
, pp. 904-908
-
-
Essers, M.A.1
Offner, S.2
Blanco-Bose, W.E.3
Waibler, Z.4
Kalinke, U.5
Duchosal, M.A.6
Trumpp, A.7
-
11
-
-
0034662159
-
Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages
-
N. Faust, F. Varas, L.M. Kelly, S. Heck, and T. Graf Insertion of enhanced green fluorescent protein into the lysozyme gene creates mice with green fluorescent granulocytes and macrophages Blood 96 2000 719 726
-
(2000)
Blood
, vol.96
, pp. 719-726
-
-
Faust, N.1
Varas, F.2
Kelly, L.M.3
Heck, S.4
Graf, T.5
-
12
-
-
84896539534
-
PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis
-
A.E. Ferreira, F. Sisti, F. Sonego, S. Wang, L.R. Filgueiras, S. Brandt, A.P. Serezani, H. Du, F.Q. Cunha, J.C. Alves-Filho, and et al. PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis J. Immunol. 192 2014 2357 2365
-
(2014)
J. Immunol.
, vol.192
, pp. 2357-2365
-
-
Ferreira, A.E.1
Sisti, F.2
Sonego, F.3
Wang, S.4
Filgueiras, L.R.5
Brandt, S.6
Serezani, A.P.7
Du, H.8
Cunha, F.Q.9
Alves-Filho, J.C.10
-
13
-
-
84893744924
-
C/EBPalpha is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors
-
M.S. Hasemann, F.K. Lauridsen, J. Waage, J.S. Jakobsen, A.K. Frank, M.B. Schuster, N. Rapin, F.O. Bagger, P.S. Hoppe, T. Schroeder, and et al. C/EBPalpha is required for long-term self-renewal and lineage priming of hematopoietic stem cells and for the maintenance of epigenetic configurations in multipotent progenitors PLoS Genet. 10 2014 e1004079
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004079
-
-
Hasemann, M.S.1
Lauridsen, F.K.2
Waage, J.3
Jakobsen, J.S.4
Frank, A.K.5
Schuster, M.B.6
Rapin, N.7
Bagger, F.O.8
Hoppe, P.S.9
Schroeder, T.10
-
14
-
-
0037426726
-
The pathophysiology and treatment of sepsis
-
R.S. Hotchkiss, and I.E. Karl The pathophysiology and treatment of sepsis N. Engl. J. Med. 348 2003 138 150
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 138-150
-
-
Hotchkiss, R.S.1
Karl, I.E.2
-
15
-
-
30344461860
-
The p38 mitogen-activated protein kinase pathway in interferon signal transduction
-
E. Katsoulidis, Y. Li, H. Mears, and L.C. Platanias The p38 mitogen-activated protein kinase pathway in interferon signal transduction J. Interferon Cytokine Res. 25 2005 749 756
-
(2005)
J. Interferon Cytokine Res.
, vol.25
, pp. 749-756
-
-
Katsoulidis, E.1
Li, Y.2
Mears, H.3
Platanias, L.C.4
-
16
-
-
0035889228
-
Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes
-
T. Kawai, O. Takeuchi, T. Fujita, J. Inoue, P.F. Muhlradt, S. Sato, K. Hoshino, and S. Akira Lipopolysaccharide stimulates the MyD88-independent pathway and results in activation of IFN-regulatory factor 3 and the expression of a subset of lipopolysaccharide-inducible genes J. Immunol. 167 2001 5887 5894
-
(2001)
J. Immunol.
, vol.167
, pp. 5887-5894
-
-
Kawai, T.1
Takeuchi, O.2
Fujita, T.3
Inoue, J.4
Muhlradt, P.F.5
Sato, S.6
Hoshino, K.7
Akira, S.8
-
17
-
-
21244463426
-
SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
-
M.J. Kiel, O.H. Yilmaz, T. Iwashita, C. Terhorst, and S.J. Morrison SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells Cell 121 2005 1109 1121
-
(2005)
Cell
, vol.121
, pp. 1109-1121
-
-
Kiel, M.J.1
Yilmaz, O.H.2
Iwashita, T.3
Terhorst, C.4
Morrison, S.J.5
-
18
-
-
0036070180
-
Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment
-
T. Miyamoto, H. Iwasaki, B. Reizis, M. Ye, T. Graf, I.L. Weissman, and K. Akashi Myeloid or lymphoid promiscuity as a critical step in hematopoietic lineage commitment Dev. Cell 3 2002 137 147
-
(2002)
Dev. Cell
, vol.3
, pp. 137-147
-
-
Miyamoto, T.1
Iwasaki, H.2
Reizis, B.3
Ye, M.4
Graf, T.5
Weissman, I.L.6
Akashi, K.7
-
19
-
-
33744978765
-
Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment
-
Y. Nagai, K.P. Garrett, S. Ohta, U. Bahrun, T. Kouro, S. Akira, K. Takatsu, and P.W. Kincade Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment Immunity 24 2006 801 812
-
(2006)
Immunity
, vol.24
, pp. 801-812
-
-
Nagai, Y.1
Garrett, K.P.2
Ohta, S.3
Bahrun, U.4
Kouro, T.5
Akira, S.6
Takatsu, K.7
Kincade, P.W.8
-
20
-
-
84889568419
-
SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors
-
H. Oguro, L. Ding, and S.J. Morrison SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors Cell Stem Cell 13 2013 102 116
-
(2013)
Cell Stem Cell
, vol.13
, pp. 102-116
-
-
Oguro, H.1
Ding, L.2
Morrison, S.J.3
-
21
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
L.A. O'Neill, and A.G. Bowie The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling Nat. Rev. Immunol. 7 2007 353 364
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
22
-
-
84875124740
-
Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: The ACCESS randomized trial
-
S.M. Opal, P.F. Laterre, B. Francois, S.P. LaRosa, D.C. Angus, J.P. Mira, X. Wittebole, T. Dugernier, D. Perrotin, M. Tidswell, and et al. Effect of eritoran, an antagonist of MD2-TLR4, on mortality in patients with severe sepsis: the ACCESS randomized trial JAMA 309 2013 1154 1162
-
(2013)
JAMA
, vol.309
, pp. 1154-1162
-
-
Opal, S.M.1
Laterre, P.F.2
Francois, B.3
LaRosa, S.P.4
Angus, D.C.5
Mira, J.P.6
Wittebole, X.7
Dugernier, T.8
Perrotin, D.9
Tidswell, M.10
-
23
-
-
84893810137
-
Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type i interferons
-
E.M. Pietras, R. Lakshminarasimhan, J.M. Techner, S. Fong, J. Flach, M. Binnewies, and E. Passegue Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons J. Exp. Med. 211 2014 245 262
-
(2014)
J. Exp. Med.
, vol.211
, pp. 245-262
-
-
Pietras, E.M.1
Lakshminarasimhan, R.2
Techner, J.M.3
Fong, S.4
Flach, J.5
Binnewies, M.6
Passegue, E.7
-
24
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
A. Poltorak, X. He, I. Smirnova, M.Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, and et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene Science 282 1998 2085 2088
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
-
25
-
-
77950389067
-
Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis
-
S. Rodriguez, A. Chora, B. Goumnerov, C. Mumaw, W.S. Goebel, L. Fernandez, H. Baydoun, H. HogenEsch, D.M. Dombkowski, C.A. Karlewicz, and et al. Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis Blood 114 2009 4064 4076
-
(2009)
Blood
, vol.114
, pp. 4064-4076
-
-
Rodriguez, S.1
Chora, A.2
Goumnerov, B.3
Mumaw, C.4
Goebel, W.S.5
Fernandez, L.6
Baydoun, H.7
HogenEsch, H.8
Dombkowski, D.M.9
Karlewicz, C.A.10
-
26
-
-
60549101332
-
Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4
-
T. Roger, C. Froidevaux, D. Le Roy, M.K. Reymond, A.L. Chanson, D. Mauri, K. Burns, B.M. Riederer, S. Akira, and T. Calandra Protection from lethal gram-negative bacterial sepsis by targeting Toll-like receptor 4 Proc. Natl. Acad. Sci. USA 106 2009 2348 2352
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 2348-2352
-
-
Roger, T.1
Froidevaux, C.2
Le Roy, D.3
Reymond, M.K.4
Chanson, A.L.5
Mauri, D.6
Burns, K.7
Riederer, B.M.8
Akira, S.9
Calandra, T.10
-
27
-
-
84876860619
-
Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells
-
P.B. Staber, P. Zhang, M. Ye, R.S. Welner, C. Nombela-Arrieta, C. Bach, M. Kerenyi, B.A. Bartholdy, H. Zhang, M. Alberich-Jorda, and et al. Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells Mol. Cell 49 2013 934 946
-
(2013)
Mol. Cell
, vol.49
, pp. 934-946
-
-
Staber, P.B.1
Zhang, P.2
Ye, M.3
Welner, R.S.4
Nombela-Arrieta, C.5
Bach, C.6
Kerenyi, M.7
Bartholdy, B.A.8
Zhang, H.9
Alberich-Jorda, M.10
-
28
-
-
84867557780
-
Differential roles of MyD88 and TRIF in hematopoietic and resident cells during murine gram-negative pneumonia
-
M.H. van Lieshout, D.C. Blok, C.W. Wieland, A.F. de Vos, C. van 't Veer, and T. van der Poll Differential roles of MyD88 and TRIF in hematopoietic and resident cells during murine gram-negative pneumonia J. Infect. Dis. 206 2012 1415 1423
-
(2012)
J. Infect. Dis.
, vol.206
, pp. 1415-1423
-
-
Van Lieshout, M.H.1
Blok, D.C.2
Wieland, C.W.3
De Vos, A.F.4
Van'T Veer, C.5
Van Der Poll, T.6
-
29
-
-
72249087115
-
International study of the prevalence and outcomes of infection in intensive care units
-
J.L. Vincent, J. Rello, J. Marshall, E. Silva, A. Anzueto, C.D. Martin, R. Moreno, J. Lipman, C. Gomersall, Y. Sakr, and et al. International study of the prevalence and outcomes of infection in intensive care units JAMA 302 2009 2323 2329
-
(2009)
JAMA
, vol.302
, pp. 2323-2329
-
-
Vincent, J.L.1
Rello, J.2
Marshall, J.3
Silva, E.4
Anzueto, A.5
Martin, C.D.6
Moreno, R.7
Lipman, J.8
Gomersall, C.9
Sakr, Y.10
-
30
-
-
37049024099
-
Role of Toll-like receptor responses for sepsis pathogenesis
-
H. Weighardt, and B. Holzmann Role of Toll-like receptor responses for sepsis pathogenesis Immunobiology 212 2007 715 722
-
(2007)
Immunobiology
, vol.212
, pp. 715-722
-
-
Weighardt, H.1
Holzmann, B.2
-
31
-
-
0037105549
-
Cutting edge: Myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection
-
H. Weighardt, S. Kaiser-Moore, R.M. Vabulas, C.J. Kirschning, H. Wagner, and B. Holzmann Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection J. Immunol. 169 2002 2823 2827
-
(2002)
J. Immunol.
, vol.169
, pp. 2823-2827
-
-
Weighardt, H.1
Kaiser-Moore, S.2
Vabulas, R.M.3
Kirschning, C.J.4
Wagner, H.5
Holzmann, B.6
-
32
-
-
1642278750
-
Identification of a TLR4- and TRIF-dependent activation program of dendritic cells
-
H. Weighardt, G. Jusek, J. Mages, R. Lang, K. Hoebe, B. Beutler, and B. Holzmann Identification of a TLR4- and TRIF-dependent activation program of dendritic cells Eur. J. Immunol. 34 2004 558 564
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 558-564
-
-
Weighardt, H.1
Jusek, G.2
Mages, J.3
Lang, R.4
Hoebe, K.5
Beutler, B.6
Holzmann, B.7
-
33
-
-
56549128268
-
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
-
A. Wilson, E. Laurenti, G. Oser, R.C. van der Wath, W. Blanco-Bose, M. Jaworski, S. Offner, C.F. Dunant, L. Eshkind, E. Bockamp, and et al. Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair Cell 135 2008 1118 1129
-
(2008)
Cell
, vol.135
, pp. 1118-1129
-
-
Wilson, A.1
Laurenti, E.2
Oser, G.3
Van Der Wath, R.C.4
Blanco-Bose, W.5
Jaworski, M.6
Offner, S.7
Dunant, C.F.8
Eshkind, L.9
Bockamp, E.10
-
34
-
-
0043176281
-
Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway
-
M. Yamamoto, S. Sato, H. Hemmi, K. Hoshino, T. Kaisho, H. Sanjo, O. Takeuchi, M. Sugiyama, M. Okabe, K. Takeda, and et al. Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway Science 301 2003 640 643
-
(2003)
Science
, vol.301
, pp. 640-643
-
-
Yamamoto, M.1
Sato, S.2
Hemmi, H.3
Hoshino, K.4
Kaisho, T.5
Sanjo, H.6
Takeuchi, O.7
Sugiyama, M.8
Okabe, M.9
Takeda, K.10
|