-
1
-
-
84861591910
-
The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology
-
[1] Chalasani, N., Younossi, Z., Lavine, J.E., Diehl, A.M., Brunt, E.M., Cusi, K., et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 142 (2012), 1592–1609.
-
(2012)
Gastroenterology
, vol.142
, pp. 1592-1609
-
-
Chalasani, N.1
Younossi, Z.2
Lavine, J.E.3
Diehl, A.M.4
Brunt, E.M.5
Cusi, K.6
-
2
-
-
0034697846
-
Identification of a novel FGF, FGF-21, preferentially expressed in the liver
-
[2] Nishimura, T., Nakatake, Y., Konishi, M., Itoh, N., Identification of a novel FGF, FGF-21, preferentially expressed in the liver. Biochim Biophys Acta 1492 (2000), 203–206.
-
(2000)
Biochim Biophys Acta
, vol.1492
, pp. 203-206
-
-
Nishimura, T.1
Nakatake, Y.2
Konishi, M.3
Itoh, N.4
-
3
-
-
84921771693
-
The role of fibroblast growth factor 21 in the pathogenesis of non-alcoholic fatty liver disease and implications for therapy
-
[3] Liu, J., Xu, Y., Hu, Y., Wang, G., The role of fibroblast growth factor 21 in the pathogenesis of non-alcoholic fatty liver disease and implications for therapy. Metabolism 64 (2015), 380–390.
-
(2015)
Metabolism
, vol.64
, pp. 380-390
-
-
Liu, J.1
Xu, Y.2
Hu, Y.3
Wang, G.4
-
4
-
-
68149091653
-
Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance
-
[4] Chavez, A.O., Molina-Carrion, M., Abdul-Ghani, M.A., Folli, F., Defronzo, R.A., Tripathy, D., Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance. Diabetes Care 32 (2009), 1542–1546.
-
(2009)
Diabetes Care
, vol.32
, pp. 1542-1546
-
-
Chavez, A.O.1
Molina-Carrion, M.2
Abdul-Ghani, M.A.3
Folli, F.4
Defronzo, R.A.5
Tripathy, D.6
-
5
-
-
33750587755
-
Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways
-
[5] Wente, W., Efanov, A.M., Bfenner, M., Kharitonenkov, A., Köster, A., Sandusky, G.E., et al. Fibroblast growth factor-21 improves pancreatic beta-cell function and survival by activation of extracellular signal-regulated kinase 1/2 and Akt signaling pathways. Diabetes 55 (2006), 2470–2478.
-
(2006)
Diabetes
, vol.55
, pp. 2470-2478
-
-
Wente, W.1
Efanov, A.M.2
Bfenner, M.3
Kharitonenkov, A.4
Köster, A.5
Sandusky, G.E.6
-
6
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
[6] Kharitonenkov, A., Shiyanova, T.L., Koester, A., Ford, A.M., Micanovic, R., Galbreath, E.J., et al. FGF-21 as a novel metabolic regulator. J Clin Invest 115 (2005), 1627–1635.
-
(2005)
J Clin Invest
, vol.115
, pp. 1627-1635
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
-
7
-
-
80055055627
-
Effects of short-term continuous subcutaneous insulin infusion on fasting plasma fibroblast growth factor-21 levels in patients with newly diagnosed type 2 diabetes mellitus
-
[7] Yang, M., Dong, J., Liu, H., Li, L., Yang, G., Effects of short-term continuous subcutaneous insulin infusion on fasting plasma fibroblast growth factor-21 levels in patients with newly diagnosed type 2 diabetes mellitus. PLoS ONE, 6, 2011, e26359.
-
(2011)
PLoS ONE
, vol.6
, pp. e26359
-
-
Yang, M.1
Dong, J.2
Liu, H.3
Li, L.4
Yang, G.5
-
8
-
-
63849189712
-
Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity
-
[8] Mraz, M., Bartlova, M., Lacinova, Z., Michalsky, D., Kasalicky, M., Haluzikova, D., et al. Serum concentrations and tissue expression of a novel endocrine regulator fibroblast growth factor-21 in patients with type 2 diabetes and obesity. Clin Endocrinol (Oxf) 71 (2009), 369–375.
-
(2009)
Clin Endocrinol (Oxf)
, vol.71
, pp. 369-375
-
-
Mraz, M.1
Bartlova, M.2
Lacinova, Z.3
Michalsky, D.4
Kasalicky, M.5
Haluzikova, D.6
-
9
-
-
80053645063
-
Serum FGF-21 levels in type 2 diabetic patients
-
[9] Cheng, X., Zhu, B., Jiang, F., Fan, H., Serum FGF-21 levels in type 2 diabetic patients. Endocr Res 36 (2011), 142–148.
-
(2011)
Endocr Res
, vol.36
, pp. 142-148
-
-
Cheng, X.1
Zhu, B.2
Jiang, F.3
Fan, H.4
-
10
-
-
70349234490
-
Effects of rosiglitazone on fasting plasma fibroblast growth factor-21 levels in patients with type 2 diabetes mellitus
-
[10] Li, K., Li, L., Yang, M., Zong, H., Liu, H., Yang, G., Effects of rosiglitazone on fasting plasma fibroblast growth factor-21 levels in patients with type 2 diabetes mellitus. Eur J Endocrinol 161 (2009), 391–395.
-
(2009)
Eur J Endocrinol
, vol.161
, pp. 391-395
-
-
Li, K.1
Li, L.2
Yang, M.3
Zong, H.4
Liu, H.5
Yang, G.6
-
11
-
-
84880469413
-
Changes of plasma fibroblast growth factor-21 (FGF-21) in oral glucose tolerance test and effects of metformin on FGF-21 levels in type 2 diabetes mellitus
-
[11] Zhang, M., Liu, Y., Xiong, Z.Y., Deng, Z.Y., Song, H.L., An, Z.M., Changes of plasma fibroblast growth factor-21 (FGF-21) in oral glucose tolerance test and effects of metformin on FGF-21 levels in type 2 diabetes mellitus. Endokrynol Pol 64 (2013), 220–224.
-
(2013)
Endokrynol Pol
, vol.64
, pp. 220-224
-
-
Zhang, M.1
Liu, Y.2
Xiong, Z.Y.3
Deng, Z.Y.4
Song, H.L.5
An, Z.M.6
-
12
-
-
78049297991
-
Obesity is a fibroblast growth factor 21 (FGF21)-resistant state
-
[12] Fisher, F.M., Chui, P.C., Antonellis, P.J., Bina, H.A., Kharitonenkov, A., Flier, J.S., et al. Obesity is a fibroblast growth factor 21 (FGF21)-resistant state. Diabetes 59 (2010), 2781–2789.
-
(2010)
Diabetes
, vol.59
, pp. 2781-2789
-
-
Fisher, F.M.1
Chui, P.C.2
Antonellis, P.J.3
Bina, H.A.4
Kharitonenkov, A.5
Flier, J.S.6
-
13
-
-
84928255405
-
Liraglutide, a glucagon-like peptide-1 analogy, increased insulin sensitivity assessed by hyperinsulinemic-euglycemic clamp examination in patients with uncontrolled type 2 diabetes mellitus
-
[13] Jinnouchi, H., Sugiyama, S., Yoshida, A., Hieshima, K., Kurinami, N., Suzuki, T., et al. Liraglutide, a glucagon-like peptide-1 analogy, increased insulin sensitivity assessed by hyperinsulinemic-euglycemic clamp examination in patients with uncontrolled type 2 diabetes mellitus. J Diabetes Res, 2015, e706416.
-
(2015)
J Diabetes Res
, pp. e706416
-
-
Jinnouchi, H.1
Sugiyama, S.2
Yoshida, A.3
Hieshima, K.4
Kurinami, N.5
Suzuki, T.6
-
14
-
-
82455212124
-
Exenatide decreases hepatic fibroblast growth factor 21 resistance in non-alcoholic fatty liver disease in a mouse model of obesity and in a randomised controlled trial
-
[14] Samson, S.L., Sathyanarayana, P., Jogi, M., Gonzalez, E.V., Gutierrez, A., Krishnamurthy, R., et al. Exenatide decreases hepatic fibroblast growth factor 21 resistance in non-alcoholic fatty liver disease in a mouse model of obesity and in a randomised controlled trial. Diabetologia 54 (2011), 3093–3100.
-
(2011)
Diabetologia
, vol.54
, pp. 3093-3100
-
-
Samson, S.L.1
Sathyanarayana, P.2
Jogi, M.3
Gonzalez, E.V.4
Gutierrez, A.5
Krishnamurthy, R.6
-
15
-
-
84900030527
-
Liraglutide suppresses obesity and hyperglycemia associated with increases in hepatic fibroblast growth factor 21 production in KKAy mice
-
[15] Nonogaki, K., Hazama, M., Satoh, N., Liraglutide suppresses obesity and hyperglycemia associated with increases in hepatic fibroblast growth factor 21 production in KKAy mice. Biomed Res Int, 2014, e751930.
-
(2014)
Biomed Res Int
, pp. e751930
-
-
Nonogaki, K.1
Hazama, M.2
Satoh, N.3
-
16
-
-
0021813187
-
Homeostasis model assessment: insulin resistance and B-cell function from fasting plasma glucose and insulin concentrations in man
-
[16] Matthews, D.R., Hosker, J.P., Rudenski, A.S., Naylor, B.A., Treacher, D.F., Turner, R.C., Homeostasis model assessment: insulin resistance and B-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28 (1995), 412–419.
-
(1995)
Diabetologia
, vol.28
, pp. 412-419
-
-
Matthews, D.R.1
Hosker, J.P.2
Rudenski, A.S.3
Naylor, B.A.4
Treacher, D.F.5
Turner, R.C.6
-
17
-
-
84869051421
-
Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance
-
[17] Yang, M., Zhang, L., Wang, C., Liu, H., Boden, G., Yang, G., et al. Liraglutide increases FGF-21 activity and insulin sensitivity in high fat diet and adiponectin knockdown induced insulin resistance. PLoS ONE, 7, 2012, e48392.
-
(2012)
PLoS ONE
, vol.7
, pp. e48392
-
-
Yang, M.1
Zhang, L.2
Wang, C.3
Liu, H.4
Boden, G.5
Yang, G.6
-
18
-
-
77955474305
-
Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease
-
[18] Dushay, J., Chui, P.C., Gopalakrishnan, G.S., Varela-Rey, M., Crawley, M., Fisher, F.M., et al. Increased fibroblast growth factor 21 in obesity and nonalcoholic fatty liver disease. Gastroenterology 139 (2010), 456–463.
-
(2010)
Gastroenterology
, vol.139
, pp. 456-463
-
-
Dushay, J.1
Chui, P.C.2
Gopalakrishnan, G.S.3
Varela-Rey, M.4
Crawley, M.5
Fisher, F.M.6
-
19
-
-
48349146527
-
Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
-
[19] Zhang, X., Yeung, D.C., Karpisek, M., Stejskal, D., Zhou, Z.G., Liu, F., et al. Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans. Diabetes 57 (2008), 1246–1253.
-
(2008)
Diabetes
, vol.57
, pp. 1246-1253
-
-
Zhang, X.1
Yeung, D.C.2
Karpisek, M.3
Stejskal, D.4
Zhou, Z.G.5
Liu, F.6
-
20
-
-
84929415426
-
Serum FGF21 levels are associated with brown adipose tissue activity in humans
-
[20] Hanssen, M.J., Broeders, E., Samms, R.J., Vosselman, M.J., van der Lans, A.A., Cheng, C.C., et al. Serum FGF21 levels are associated with brown adipose tissue activity in humans. Sci Rep, 5, 2015, 10275.
-
(2015)
Sci Rep
, vol.5
, pp. 10275
-
-
Hanssen, M.J.1
Broeders, E.2
Samms, R.J.3
Vosselman, M.J.4
van der Lans, A.A.5
Cheng, C.C.6
-
21
-
-
84946739962
-
Fibroblast growth factor-21, energy balance and obesity
-
[21] Giralt, M., Gavaldà-Navarro, A., Villarroya, F., Fibroblast growth factor-21, energy balance and obesity. Mol Cell Endocrinol 418 (2015), 66–73.
-
(2015)
Mol Cell Endocrinol
, vol.418
, pp. 66-73
-
-
Giralt, M.1
Gavaldà-Navarro, A.2
Villarroya, F.3
-
22
-
-
84865422329
-
TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathway
-
[22] Díaz-Delfín, J., Hondares, E., Iglesias, R., Giralt, M., Caelles, C., Villarroya, F., et al. TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathway. Endocrinology 153 (2012), 4238–4245.
-
(2012)
Endocrinology
, vol.153
, pp. 4238-4245
-
-
Díaz-Delfín, J.1
Hondares, E.2
Iglesias, R.3
Giralt, M.4
Caelles, C.5
Villarroya, F.6
-
23
-
-
54949146796
-
Gene therapy for diabetes: metabolic effects of helper-dependent adenoviral exendin 4 expression in a diet-induced obesity mouse model
-
[23] Samson, S.L., Gonzalez, E.V., Yechoor, V., Bajaj, M., Oka, K., Chan, L., Gene therapy for diabetes: metabolic effects of helper-dependent adenoviral exendin 4 expression in a diet-induced obesity mouse model. Mol Ther 16 (2009), 1805–1812.
-
(2009)
Mol Ther
, vol.16
, pp. 1805-1812
-
-
Samson, S.L.1
Gonzalez, E.V.2
Yechoor, V.3
Bajaj, M.4
Oka, K.5
Chan, L.6
-
24
-
-
84883179637
-
Eight weeks of treatment with long-acting GLP-1 analog taspoglutide improves postprandial insulin secretion and sensitivity in metformin-treated patients with type 2 diabetes
-
[24] Gastaldelli, A., Nauck, M.A., Balena, R., Eight weeks of treatment with long-acting GLP-1 analog taspoglutide improves postprandial insulin secretion and sensitivity in metformin-treated patients with type 2 diabetes. Metabolism 62 (2013), 1330–1339.
-
(2013)
Metabolism
, vol.62
, pp. 1330-1339
-
-
Gastaldelli, A.1
Nauck, M.A.2
Balena, R.3
-
25
-
-
78649878256
-
Exenatide in the treatment of diabetic patients with non-alcoholic steatohepatitis: a case series
-
[25] Kenny, P.R., Brady, D.E., Torres, D.M., Ragozzino, L., Chalasani, N., Harrison, S.A., Exenatide in the treatment of diabetic patients with non-alcoholic steatohepatitis: a case series. Am J Gastroenterol 105 (2010), 2707–2709.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 2707-2709
-
-
Kenny, P.R.1
Brady, D.E.2
Torres, D.M.3
Ragozzino, L.4
Chalasani, N.5
Harrison, S.A.6
-
26
-
-
84960970251
-
Fibroblast growth factor 21 (FGF21) protects against high fat diet induced inflammation and islet hyperplasia in pancreas
-
[26] Singhal, G., Fisher, F.M., Chee, M.J., Tan, T.G., El Ouaamari, A., Adams, A.C., et al. Fibroblast growth factor 21 (FGF21) protects against high fat diet induced inflammation and islet hyperplasia in pancreas. PLOS ONE, 11, 2016, e0148252.
-
(2016)
PLOS ONE
, vol.11
, pp. e0148252
-
-
Singhal, G.1
Fisher, F.M.2
Chee, M.J.3
Tan, T.G.4
El Ouaamari, A.5
Adams, A.C.6
-
27
-
-
84937635957
-
Antidiabetic agents: potential anti-inflammatory activity beyond glucose control
-
[27] Scheen, A.J., Esser, N., Paquot, N., Antidiabetic agents: potential anti-inflammatory activity beyond glucose control. Diabetes Metab 41 (2015), 183–194.
-
(2015)
Diabetes Metab
, vol.41
, pp. 183-194
-
-
Scheen, A.J.1
Esser, N.2
Paquot, N.3
-
28
-
-
0032896330
-
Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulphonylureas
-
[28] Emoto, M., Nishizawa, Y., Maekawa, K., Hiura, Y., Kanda, H., Kawagishi, T., et al. Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulphonylureas. Diabetes Care 22 (1999), 818–822.
-
(1999)
Diabetes Care
, vol.22
, pp. 818-822
-
-
Emoto, M.1
Nishizawa, Y.2
Maekawa, K.3
Hiura, Y.4
Kanda, H.5
Kawagishi, T.6
-
29
-
-
0032821965
-
Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp
-
[29] Matsuda, M., DeFronzo, R., Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 22 (1999), 1462–1470.
-
(1999)
Diabetes Care
, vol.22
, pp. 1462-1470
-
-
Matsuda, M.1
DeFronzo, R.2
-
30
-
-
0035089445
-
A model-based method for assessing insulin sensitivity from the OGTT
-
[30] Mari, A., Pacini, G., Murphy, E., Ludvik, B., Nolan, J.J., A model-based method for assessing insulin sensitivity from the OGTT. Diabetes Care 24 (2001), 539–548.
-
(2001)
Diabetes Care
, vol.24
, pp. 539-548
-
-
Mari, A.1
Pacini, G.2
Murphy, E.3
Ludvik, B.4
Nolan, J.J.5
-
31
-
-
0033941315
-
Homeostasis model assessment and related simplified evaluations of insulin sensitivity from fasting insulin and glucose
-
[31] Brun, J.F., Raynaud, E., Mercier, J., Homeostasis model assessment and related simplified evaluations of insulin sensitivity from fasting insulin and glucose. Diabetes Care 23 (2000), 1037–1038.
-
(2000)
Diabetes Care
, vol.23
, pp. 1037-1038
-
-
Brun, J.F.1
Raynaud, E.2
Mercier, J.3
|