메뉴 건너뛰기




Volumn 22, Issue 17, 2016, Pages 2453-2462

Selected engineering and physicochemical aspects of systemic drug delivery by inhalation

Author keywords

Aerosol; Air blood barrier; Deposition; Inhalation; Particles; Surfactant

Indexed keywords

DRUG CARRIER; NANOCARRIER; RECOMBINANT HUMAN INSULIN; DRUG;

EID: 84974678232     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612822666160128145644     Document Type: Review
Times cited : (13)

References (94)
  • 2
    • 0346672501 scopus 로고    scopus 로고
    • Epidemiological evidence of the effects of ultrafine particle exposure
    • Wichmann HE, Peters A. Epidemiological evidence of the effects of ultrafine particle exposure. Phil Trans R Soc Lond A 2000; 358: 2751-69.
    • (2000) Phil Trans R Soc Lond A , vol.358 , pp. 2751-2769
    • Wichmann, H.E.1    Peters, A.2
  • 3
    • 65849518360 scopus 로고    scopus 로고
    • Nitrous oxide and the inhalation anesthetics
    • Becker DE, Rosenberg M. Nitrous oxide and the inhalation anesthetics. Anesth Prog 2008; 55(4): 124-31.
    • (2008) Anesth Prog , vol.55 , Issue.4 , pp. 124-131
    • Becker, D.E.1    Rosenberg, M.2
  • 4
    • 84919666239 scopus 로고    scopus 로고
    • Dosimetry of inhaled nanoparticles
    • Marijnissen J, Gradoń L, Eds. Dordrecht: Springer
    • Kreyling WG, Geiser M. Dosimetry of inhaled nanoparticles. In: Marijnissen J, Gradoń L, Eds. Nanoparticles in environment and medicine. Dordrecht: Springer 2010; pp: 145-71.
    • (2010) Nanoparticles in environment and medicine , pp. 145-171
    • Kreyling, W.G.1    Geiser, M.2
  • 5
    • 0343058935 scopus 로고    scopus 로고
    • Mechanisms of macromolecule absorption by the lungs
    • Patton JS. Mechanisms of macromolecule absorption by the lungs. Adv Drug Deliv Rev 1996; 19(1): 3-36.
    • (1996) Adv Drug Deliv Rev , vol.19 , Issue.1 , pp. 3-36
    • Patton, J.S.1
  • 6
    • 26944439522 scopus 로고    scopus 로고
    • The lungs as a portal of entry for systemic drug delivery
    • Patton JS, Fishburn CS, Weers JG. The lungs as a portal of entry for systemic drug delivery. Proc Am Thorac Soc 2004; 1: 338-44.
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 338-344
    • Patton, J.S.1    Fishburn, C.S.2    Weers, J.G.3
  • 7
    • 33751233271 scopus 로고    scopus 로고
    • Clinical evaluation of inhaled insulin
    • Mastrandrea LD, Quattrin T. Clinical evaluation of inhaled insulin. Adv Drug Del Rev 2006; 58: 1061-75.
    • (2006) Adv Drug Del Rev , vol.58 , pp. 1061-1075
    • Mastrandrea, L.D.1    Quattrin, T.2
  • 8
    • 77955984808 scopus 로고    scopus 로고
    • Treatment of systemic diseases by inhalation of biomolecule aerosols
    • Siekmeier R, Scheuch G. Treatment of systemic diseases by inhalation of biomolecule aerosols. J Physiol Pharmacol 2009; 60 (Suppl 5): 15-26.
    • (2009) J Physiol Pharmacol , vol.60 , pp. 15-26
    • Siekmeier, R.1    Scheuch, G.2
  • 9
    • 84874709963 scopus 로고    scopus 로고
    • Back to the future: Inhaled drug products
    • Hickey AJ. Back to the future: inhaled drug products. J Pharm Sci. 2013; 102(4): 1165-72.
    • (2013) J Pharm Sci. , vol.102 , Issue.4 , pp. 1165-1172
    • Hickey, A.J.1
  • 10
    • 84944729759 scopus 로고    scopus 로고
    • Aerosolized medications for gene and peptide therapy
    • Laube BL. Aerosolized medications for gene and peptide therapy. Respir Care 2015; 60(6): 806-24.
    • (2015) Respir Care , vol.60 , Issue.6 , pp. 806-824
    • Laube, B.L.1
  • 11
    • 84905725777 scopus 로고    scopus 로고
    • Inhaled nebulized and intranasal opioids for the relief of breathlessness
    • Bausewein C, Simon ST. Inhaled nebulized and intranasal opioids for the relief of breathlessness. Curr Opin Support Palliat Care 2014; 8(3): 208-12.
    • (2014) Curr Opin Support Palliat Care , vol.8 , Issue.3 , pp. 208-212
    • Bausewein, C.1    Simon, S.T.2
  • 12
    • 38649087934 scopus 로고    scopus 로고
    • Human health effects of air pollution
    • Kampa M, Castanas E. Human health effects of air pollution. Environ Pollut 2008; 51(2): 362-7.
    • (2008) Environ Pollut , vol.51 , Issue.2 , pp. 362-367
    • Kampa, M.1    Castanas, E.2
  • 13
    • 84875516600 scopus 로고    scopus 로고
    • Nasal drug delivery devices: Characteristics and performance in a clinical perspective-a review
    • Djupesland PG. Nasal drug delivery devices: characteristics and performance in a clinical perspective-a review. Drug Deliv Transl Res 2013; 3(1): 42-62.
    • (2013) Drug Deliv Transl Res , vol.3 , Issue.1 , pp. 42-62
    • Djupesland, P.G.1
  • 14
    • 84907216206 scopus 로고    scopus 로고
    • Intranasal formulations: Promising strategy to deliver vaccines
    • Riese P, Sakthivel P, Trittel S, Guzmán CA. Intranasal formulations: promising strategy to deliver vaccines. Expert Opin Drug Deliv 2014; 11(10): 1619-34.
    • (2014) Expert Opin Drug Deliv , vol.11 , Issue.10 , pp. 1619-1634
    • Riese, P.1    Sakthivel, P.2    Trittel, S.3    Guzmán, C.A.4
  • 15
    • 84904310183 scopus 로고    scopus 로고
    • Quantitative analysis of drug delivery to the brain via nasal route
    • Kozlovskaya L, Abou-Kaoud M, Stepensky D. Quantitative analysis of drug delivery to the brain via nasal route. J Control Release 2014; 189: 133-40.
    • (2014) J Control Release , vol.189 , pp. 133-140
    • Kozlovskaya, L.1    Abou-Kaoud, M.2    Stepensky, D.3
  • 17
    • 85086053515 scopus 로고    scopus 로고
    • Strasbourg: European Directorate for the Quality of Medicines and Healthcare
    • th ed. Strasbourg: European Directorate for the Quality of Medicines and Healthcare 2013.
    • (2013) th ed
  • 18
    • 33646431138 scopus 로고    scopus 로고
    • Esophageal candidiasis as a side effect of inhaled fluticasone propionate dry powder: Recovery by switching over to hydrofluoroalkane-134a beclomethasone dipropionate (HFA-BDP)
    • Kobayashi Y, Yasuba H, Kudou M, Hamada K, Kita H. Esophageal candidiasis as a side effect of inhaled fluticasone propionate dry powder: recovery by switching over to hydrofluoroalkane-134a beclomethasone dipropionate (HFA-BDP). Int J Clin Pharmacol Ther 2006; 44(5): 193-7.
    • (2006) Int J Clin Pharmacol Ther , vol.44 , Issue.5 , pp. 193-197
    • Kobayashi, Y.1    Yasuba, H.2    Kudou, M.3    Hamada, K.4    Kita, H.5
  • 19
    • 33745284283 scopus 로고    scopus 로고
    • Local oropharyngeal side effects of inhaled corticosteroids in patients with asthma
    • Buhl R. Local oropharyngeal side effects of inhaled corticosteroids in patients with asthma. Allergy 2006; 61(5): 518-26.
    • (2006) Allergy , vol.61 , Issue.5 , pp. 518-526
    • Buhl, R.1
  • 20
    • 50249100805 scopus 로고    scopus 로고
    • Targetting aerosols to disease areas
    • Gradoń L, Marijnissen J. Eds. Dordrecht: Kluwer
    • Zanen P. Targetting aerosols to disease areas. In: Gradoń L, Marijnissen J. Eds. Optimization of aerosol drug delivery. Dordrecht: Kluwer 2003; pp. 243-76.
    • (2003) Optimization of aerosol drug delivery , pp. 243-276
    • Zanen, P.1
  • 22
    • 84863197414 scopus 로고    scopus 로고
    • Regional quantification of muscarinic acetylcholine receptors and β-adrenoceptors in human airways
    • Ikeda T. Regional quantification of muscarinic acetylcholine receptors and β-adrenoceptors in human airways. Br J Pharmacol 2012; 166(6): 1804-14.
    • (2012) Br J Pharmacol , vol.166 , Issue.6 , pp. 1804-1814
    • Ikeda, T.1
  • 23
    • 0033542041 scopus 로고    scopus 로고
    • Systemic adverse effects of inhaled corticosteroid therapy a systemic review and meta-analysis
    • Lipworth BJ. Systemic adverse effects of inhaled corticosteroid therapy a systemic review and meta-analysis. Arch Intern Med 1999; 159: 941-55.
    • (1999) Arch Intern Med , vol.159 , pp. 941-955
    • Lipworth, B.J.1
  • 24
    • 33645231621 scopus 로고    scopus 로고
    • Effects of long term inhaled corticosteroid on adrenal function in a patient with asthma
    • White M, Crisalida T, Li H, Economides A, Kaliner M. Effects of long term inhaled corticosteroid on adrenal function in a patient with asthma. Ann Allergy Asthma Immunol 2006; 96: 437-44.
    • (2006) Ann Allergy Asthma Immunol , vol.96 , pp. 437-444
    • White, M.1    Crisalida, T.2    Li, H.3    Economides, A.4    Kaliner, M.5
  • 25
    • 0003192699 scopus 로고
    • Human respiratory tract model for radiological protection
    • International Council for Radiological Protection. Human respiratory tract model for radiological protection. ICRP Publication 66 Ann ICRP 1994; 24: 231.
    • (1994) ICRP Publication 66 Ann ICRP , vol.24 , pp. 231
  • 27
    • 0035078971 scopus 로고    scopus 로고
    • Particle deposition in a multiple-path model of the human lung
    • Asgharian B, Hofmann W, Bergmann R. Particle deposition in a multiple-path model of the human lung. Aerosol Sci Technol 2001; 34: 332-9.
    • (2001) Aerosol Sci Technol , vol.34 , pp. 332-339
    • Asgharian, B.1    Hofmann, W.2    Bergmann, R.3
  • 28
    • 84974700901 scopus 로고    scopus 로고
    • [cited: 17.06.2015]
    • MPPD software. http: //www.ara.com/products/mppd.htm [cited: 17.06.2015]
    • MPPD software.
  • 29
    • 48249139478 scopus 로고    scopus 로고
    • Recent advances in predictive understanding of respiratory tract deposition
    • Finlay WH, Martin AE. Recent advances in predictive understanding of respiratory tract deposition. J Aerosol Med Pulm Drug Deliv 2008; 21: 189-206.
    • (2008) J Aerosol Med Pulm Drug Deliv , vol.21 , pp. 189-206
    • Finlay, W.H.1    Martin, A.E.2
  • 30
    • 84974738640 scopus 로고    scopus 로고
    • [cited: 17.06.2015]
    • ARLA. http: //www.mece.ualberta.ca/arla/deposition_calculator. html [cited: 17.06.2015]
    • ARLA.
  • 31
    • 0036845924 scopus 로고    scopus 로고
    • Temporary and spatial deposition of aerosol particles in the upper human airways during breathing cycle
    • Moskal A, Gradoń L. Temporary and spatial deposition of aerosol particles in the upper human airways during breathing cycle. J Aerosol Sci 2002; 33 (11): 1525-39.
    • (2002) J Aerosol Sci , vol.33 , Issue.11 , pp. 1525-1539
    • Moskal, A.1    Gradoń, L.2
  • 32
    • 35549005398 scopus 로고    scopus 로고
    • Secondary velocity fields in the conducting airways of the human lung
    • Fresconi FE, Prasad AK. Secondary velocity fields in the conducting airways of the human lung. J Biomech Eng 2007; 129(5): 722-32.
    • (2007) J Biomech Eng , vol.129 , Issue.5 , pp. 722-732
    • Fresconi, F.E.1    Prasad, A.K.2
  • 33
    • 33745261802 scopus 로고    scopus 로고
    • Dynamics of oropharyngeal aerosol transport and deposition with the realistic flow pattern
    • Sosnowski TR, Moskal A, Gradoń L. Dynamics of oropharyngeal aerosol transport and deposition with the realistic flow pattern. Inhal Toxicol 2006; 18(10): 773-80.
    • (2006) Inhal Toxicol , vol.18 , Issue.10 , pp. 773-780
    • Sosnowski, T.R.1    Moskal, A.2    Gradoń, L.3
  • 34
    • 33846230643 scopus 로고    scopus 로고
    • Mechanims of aerosol particle deposition in the oro-pharynx under non-steady airflow
    • Sosnowski TR, Moskal A, Gradon L. Mechanims of aerosol particle deposition in the oro-pharynx under non-steady airflow. Ann Occup Hyg 2007; 51(1): 19-25.
    • (2007) Ann Occup Hyg , vol.51 , Issue.1 , pp. 19-25
    • Sosnowski, T.R.1    Moskal, A.2    Gradon, L.3
  • 35
    • 33846076698 scopus 로고    scopus 로고
    • Degree of throat deposition can explain the variability in lung deposition of inhaled drugs
    • Borgström L, Olsson B, Thorsson L. Degree of throat deposition can explain the variability in lung deposition of inhaled drugs. J Aerosol Med 2006; 19(4): 473-83.
    • (2006) J Aerosol Med , vol.19 , Issue.4 , pp. 473-483
    • Borgström, L.1    Olsson, B.2    Thorsson, L.3
  • 36
    • 0037038303 scopus 로고    scopus 로고
    • A facile method of delivery of liposomes by nebulization
    • Desai TR, Hancock REW, Finlay WH. A facile method of delivery of liposomes by nebulization. J Control Release 2002; 84(1-2): 69-78.
    • (2002) J Control Release , vol.84 , Issue.1-2 , pp. 69-78
    • Desai, T.R.1    Hancock, R.E.W.2    Finlay, W.H.3
  • 38
    • 0029586446 scopus 로고
    • Nebulization of fluids of different physicochemical properties with air-jet and ultrasonic nebulizers
    • McCallion ONM, Taylor KMG, Thomas M, Taylor AJ. Nebulization of fluids of different physicochemical properties with air-jet and ultrasonic nebulizers. Pharm Res 1995; 12: 1682-8.
    • (1995) Pharm Res , vol.12 , pp. 1682-1688
    • McCallion, O.N.M.1    Taylor, K.M.G.2    Thomas, M.3    Taylor, A.J.4
  • 39
    • 84924308274 scopus 로고    scopus 로고
    • The effect of shear and extensional viscosities on atomization of Newtonian and non-Newtonian fluids in ultrasonic inhaler
    • Broniarz-Press L, Sosnowski TR, Matuszak M, Ochowiak M, Jabłczyńska K. The effect of shear and extensional viscosities on atomization of Newtonian and non-Newtonian fluids in ultrasonic inhaler. Int J Pharmaceutics 2015; 485: 41-9.
    • (2015) Int J Pharmaceutics , vol.485 , pp. 41-49
    • Broniarz-Press, L.1    Sosnowski, T.R.2    Matuszak, M.3    Ochowiak, M.4    Jabłczyńska, K.5
  • 40
    • 33746347407 scopus 로고    scopus 로고
    • The need to improve inhalation technique in Europe: A report from the Aerosol Drug Management Improvement Team
    • Crompton GK, Barnes PJ, Broeders M, et al. The need to improve inhalation technique in Europe: A report from the Aerosol Drug Management Improvement Team. Respir Med 2006; 100: 1479-94.
    • (2006) Respir Med , vol.100 , pp. 1479-1494
    • Crompton, G.K.1    Barnes, P.J.2    Broeders, M.3
  • 41
    • 84871385237 scopus 로고    scopus 로고
    • Inhaler competence in asthma: Common errors, barriers to use and recommended solutions
    • Inhaler Error Steering Committee, Price D, Bosnic-Anticevich S, et al. Inhaler competence in asthma: common errors, barriers to use and recommended solutions. Respir Med 2013; 107: 37-46.
    • (2013) Respir Med , vol.107 , pp. 37-46
    • Price, D.1    Bosnic-Anticevich, S.2
  • 42
    • 0036178365 scopus 로고    scopus 로고
    • Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability
    • Giraud V, Roche N. Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability. Eur Resp J 2002; 19: 246-51.
    • (2002) Eur Resp J , vol.19 , pp. 246-251
    • Giraud, V.1    Roche, N.2
  • 43
    • 47049128164 scopus 로고    scopus 로고
    • Dry powder inhalers (DPIs)-a review of device reliability and innovation
    • Islam N, Gladki E. Dry powder inhalers (DPIs)-a review of device reliability and innovation. Int J Pharm 2008; 360: 1-11.
    • (2008) Int J Pharm , vol.360 , pp. 1-11
    • Islam, N.1    Gladki, E.2
  • 44
    • 84890213051 scopus 로고    scopus 로고
    • Fluidization and break-up of powder particle aggregates during constant and pulsating flow in converging nozzles
    • Sosnowski TR, Giżyńska K, Żywczyk Ł. Fluidization and break-up of powder particle aggregates during constant and pulsating flow in converging nozzles. Coll Surf A: Physicochem Eng Asp 2014; 441: 905-11.
    • (2014) Coll Surf A: Physicochem Eng Asp , vol.441 , pp. 905-911
    • Sosnowski, T.R.1    Giżyńska, K.2    Żywczyk, Ł.3
  • 45
    • 84896404056 scopus 로고    scopus 로고
    • Formation of particles for dry powder inhalers
    • Gradoń L, Sosnowski TR. Formation of particles for dry powder inhalers. Adv Powder Technol 2014; 25(1): 43-55.
    • (2014) Adv Powder Technol , vol.25 , Issue.1 , pp. 43-55
    • Gradoń, L.1    Sosnowski, T.R.2
  • 46
    • 38649110436 scopus 로고    scopus 로고
    • Turbulent flow energy for aerosolization of powder particles
    • Gac J, Sosnowski TR, Gradoń L. Turbulent flow energy for aerosolization of powder particles. J Aerosol Sci 2008; 39: 113-26.
    • (2008) J Aerosol Sci , vol.39 , pp. 113-126
    • Gac, J.1    Sosnowski, T.R.2    Gradoń, L.3
  • 47
    • 59349083375 scopus 로고    scopus 로고
    • Resuspension of particles from surfaces: Technological, environmental and pharmaceutical aspects
    • Gradoń L. Resuspension of particles from surfaces: technological, environmental and pharmaceutical aspects. Adv Powder Technol 2009; 20 (1): 17-28.
    • (2009) Adv Powder Technol , vol.20 , Issue.1 , pp. 17-28
    • Gradoń, L.1
  • 48
    • 84885003284 scopus 로고    scopus 로고
    • Pure insulin highly respirable powders for inhalation
    • Balducci AG, Cagnani S, Sonvico F, et al. Pure insulin highly respirable powders for inhalation. Eur J Pharm Sci 2014; 51: 110-7.
    • (2014) Eur J Pharm Sci , vol.51 , pp. 110-117
    • Balducci, A.G.1    Cagnani, S.2    Sonvico, F.3
  • 49
    • 84924589091 scopus 로고    scopus 로고
    • Preparation and characterization of biocompatible polymer particles as potential nanocarriers for inhalation therapy
    • Jabłczyńska K, Janczewska M, Kulikowska A, Sosnowski TR. Preparation and characterization of biocompatible polymer particles as potential nanocarriers for inhalation therapy. Int J Polymer Sci 2015; 2015: 763020.
    • (2015) Int J Polymer Sci , vol.2015
    • Jabłczyńska, K.1    Janczewska, M.2    Kulikowska, A.3    Sosnowski, T.R.4
  • 50
    • 0035656483 scopus 로고    scopus 로고
    • In vitro aerosol performance and dose uniformity between the Foradile Aerolizer and the Oxis Turbuhaler
    • Chew NY, Chan HK. In vitro aerosol performance and dose uniformity between the Foradile Aerolizer and the Oxis Turbuhaler. J Aerosol Med 2001; 14(4): 495-501.
    • (2001) J Aerosol Med , vol.14 , Issue.4 , pp. 495-501
    • Chew, N.Y.1    Chan, H.K.2
  • 51
    • 73949092864 scopus 로고    scopus 로고
    • Dynamics of aerosol pulse in a simplified mouth-throat geometry and its significance for inhalation drug delivery
    • Moskal A, Sosnowski TR. Dynamics of aerosol pulse in a simplified mouth-throat geometry and its significance for inhalation drug delivery. Inz Chem Proc 2009; 30: 545-58.
    • (2009) Inz Chem Proc , vol.30 , pp. 545-558
    • Moskal, A.1    Sosnowski, T.R.2
  • 52
    • 33846083776 scopus 로고    scopus 로고
    • Influence of realistic inspiratory flow profiles on fine particle fractions of dry powder aerosol formulations
    • Martin GP, Marriott C, Zeng XM. Influence of realistic inspiratory flow profiles on fine particle fractions of dry powder aerosol formulations. Pharm Res 2007; 24(2): 361-9.
    • (2007) Pharm Res , vol.24 , Issue.2 , pp. 361-369
    • Martin, G.P.1    Marriott, C.2    Zeng, X.M.3
  • 53
    • 0027978050 scopus 로고
    • Reduction in patient timing errors using a breath-activated metered dose inhaler
    • Hampson NB, Mueller MP. Reduction in patient timing errors using a breath-activated metered dose inhaler. Chest 1994; 106(2): 462-5.
    • (1994) Chest , vol.106 , Issue.2 , pp. 462-465
    • Hampson, N.B.1    Mueller, M.P.2
  • 54
    • 0037235266 scopus 로고    scopus 로고
    • Improvement of asthma control with a breath-actuated pressurised metered dose inhaler (BAI): A prescribing claims study of 5556 patients using a traditional pressurised metered dose inhaler (MDI) or a breath-actuated device
    • Price D, Thomas M, Mitchell G, Niziol C, Featherstone R. Improvement of asthma control with a breath-actuated pressurised metered dose inhaler (BAI): a prescribing claims study of 5556 patients using a traditional pressurised metered dose inhaler (MDI) or a breath-actuated device. Respirat Med 2003; 97(1): 12-9.
    • (2003) Respirat Med , vol.97 , Issue.1 , pp. 12-19
    • Price, D.1    Thomas, M.2    Mitchell, G.3    Niziol, C.4    Featherstone, R.5
  • 55
    • 77955504099 scopus 로고    scopus 로고
    • Novel devices for individualized controlled inhalation can optimize aerosol therapy in efficacy, patient care and power of clinical trials
    • Fischer A, Stegemann J, Scheuch G, Siekmeier R. Novel devices for individualized controlled inhalation can optimize aerosol therapy in efficacy, patient care and power of clinical trials. Eur J Med Res 2009; 14 (Suppl 4): 71-7.
    • (2009) Eur J Med Res , vol.14 , pp. 71-77
    • Fischer, A.1    Stegemann, J.2    Scheuch, G.3    Siekmeier, R.4
  • 56
    • 77950606953 scopus 로고    scopus 로고
    • The Adaptive Aerosol Delivery (AAD) technology: Past, present, and future
    • Denyer J, Dyche T. The Adaptive Aerosol Delivery (AAD) technology: past, present, and future. J Aerosol Med Pulm Drug Deliv 2010; 23 (Suppl 1): S1-10.
    • (2010) J Aerosol Med Pulm Drug Deliv , vol.23 , pp. S1-S10
    • Denyer, J.1    Dyche, T.2
  • 57
    • 0041334256 scopus 로고    scopus 로고
    • Control of the morphology of nanostructured particles prepared by the spray drying of a nanoparticle sol
    • Iskandar F, Gradon L, Okuyama K. Control of the morphology of nanostructured particles prepared by the spray drying of a nanoparticle sol. J Colloid Interface Sci 2003; 265(2): 296-303.
    • (2003) J Colloid Interface Sci , vol.265 , Issue.2 , pp. 296-303
    • Iskandar, F.1    Gradon, L.2    Okuyama, K.3
  • 58
    • 84887043799 scopus 로고    scopus 로고
    • Self-assembly of colloidal nanoparticles inside charged droplets during spray-drying in the fabrication of nanostructured particles
    • Suhendi A, Nandiyanto AB, Munir MM, Ogi T, Gradon L, Okuyama K. Self-assembly of colloidal nanoparticles inside charged droplets during spray-drying in the fabrication of nanostructured particles. Langmuir 2013; 29(43): 13152-61.
    • (2013) Langmuir , vol.29 , Issue.43 , pp. 13152-13161
    • Suhendi, A.1    Nandiyanto, A.B.2    Munir, M.M.3    Ogi, T.4    Gradon, L.5    Okuyama, K.6
  • 59
    • 0027502429 scopus 로고
    • Lung dosimetry: Pulmonary clearance of inhaled particles
    • Oberdörster G. Lung dosimetry: pulmonary clearance of inhaled particles. Aerosol Sci Tech 1993; 18: 279-89.
    • (1993) Aerosol Sci Tech , vol.18 , pp. 279-289
    • Oberdörster, G.1
  • 60
    • 0343637886 scopus 로고
    • Model of particle-alveolar macrophage relationships during alveolar clearance of a low lung burden of instilled particles
    • Bernardin MP, Lehnert BE. Model of particle-alveolar macrophage relationships during alveolar clearance of a low lung burden of instilled particles. J Aerosol Sci 1995; 26(2): 319-33.
    • (1995) J Aerosol Sci , vol.26 , Issue.2 , pp. 319-333
    • Bernardin, M.P.1    Lehnert, B.E.2
  • 61
    • 0027642665 scopus 로고
    • An improved mathematical model of hydrodynamical self-cleansing of pulmonary alveoli
    • Podgórski A, Grado L. An improved mathematical model of hydrodynamical self-cleansing of pulmonary alveoli. Ann Occup Hyg 1993; 37(4): 347-65.
    • (1993) Ann Occup Hyg , vol.37 , Issue.4 , pp. 347-365
    • Podgórski, A.1    Grado, L.2
  • 62
    • 0029329291 scopus 로고
    • Displacement of alveolar macrophages in air space of human lung
    • Grado L, Podgórski A. Displacement of alveolar macrophages in air space of human lung. Med Biol Eng Comput 1995; 33(4): 575-81.
    • (1995) Med Biol Eng Comput , vol.33 , Issue.4 , pp. 575-581
    • Grado, L.1    Podgórski, A.2
  • 63
    • 84920747462 scopus 로고    scopus 로고
    • Nanosized and nanostructured particles in pulmonary drug delivery
    • Sosnowski TR. Nanosized and nanostructured particles in pulmonary drug delivery. J Nanosci Nanotechnol 2015; 15: 3476-87.
    • (2015) J Nanosci Nanotechnol , vol.15 , pp. 3476-3487
    • Sosnowski, T.R.1
  • 64
    • 0024866479 scopus 로고
    • Hydrodynamical model of pulmonary clearance
    • Grado L, Podgórski A. Hydrodynamical model of pulmonary clearance. Chem Eng Sci 1989; 44: 741-9.
    • (1989) Chem Eng Sci , vol.44 , pp. 741-749
    • Grado, L.1    Podgórski, A.2
  • 65
    • 0029970761 scopus 로고    scopus 로고
    • Experimental and theoretical investigations of transport properties of DPPC monolayer
    • Grado L, Podgórski A, Sosnowski TR. Experimental and theoretical investigations of transport properties of DPPC monolayer. J Aerosol Med 1996; 9: 357-67.
    • (1996) J Aerosol Med , vol.9 , pp. 357-367
    • Grado, L.1    Podgórski, A.2    Sosnowski, T.R.3
  • 66
    • 0034527992 scopus 로고    scopus 로고
    • Influence of insoluble aerosol deposits on the surface activity of the pulmonary surfactant: A possible mechanism of alveolar clearance retardation?
    • Sosnowski TR, Grado L Podgorski A. Influence of insoluble aerosol deposits on the surface activity of the pulmonary surfactant: a possible mechanism of alveolar clearance retardation? Aerosol Sci Technol 2000; 32(1): 52-60.
    • (2000) Aerosol Sci Technol , vol.32 , Issue.1 , pp. 52-60
    • Sosnowski, T.R.1    Grado, L.2    Podgorski, A.3
  • 67
    • 0033256839 scopus 로고    scopus 로고
    • Assessment of the pulmonary toxicity of inhaled gases and particles with physicochemical methods
    • Podgórski A, Sosnowski TR. Assessment of the pulmonary toxicity of inhaled gases and particles with physicochemical methods. Int J Occup Safety Ergon 1999; 5(3): 431-47.
    • (1999) Int J Occup Safety Ergon , vol.5 , Issue.3 , pp. 431-447
    • Podgórski, A.1    Sosnowski, T.R.2
  • 68
    • 0035653677 scopus 로고    scopus 로고
    • Deactivation of the pulmonary surfactant dynamics by toxic aerosols and gases
    • Podgórski A, Sosnowski TR, Grado L. Deactivation of the pulmonary surfactant dynamics by toxic aerosols and gases. J Aerosol Med 2001; 14(4): 455-66.
    • (2001) J Aerosol Med , vol.14 , Issue.4 , pp. 455-466
    • Podgórski, A.1    Sosnowski, T.R.2    Grado, L.3
  • 69
    • 84939417935 scopus 로고    scopus 로고
    • Dynamic tensiometry studies on interactions of novel therapeutic inhalable powders with model pulmonary surfactant at the air-water interface
    • Kramek-Romanowska K, Odziomek M, Sosnowski TR. Dynamic tensiometry studies on interactions of novel therapeutic inhalable powders with model pulmonary surfactant at the air-water interface. Coll Surf A: Physicochem Eng Aspects 2015; 480: 149-58.
    • (2015) Coll Surf A: Physicochem Eng Aspects , vol.480 , pp. 149-158
    • Kramek-Romanowska, K.1    Odziomek, M.2    Sosnowski, T.R.3
  • 70
    • 31244437255 scopus 로고    scopus 로고
    • Sorption-induced Marangoni microflows in the pulmonary surfactant system
    • Sosnowski T.R. Sorption-induced Marangoni microflows in the pulmonary surfactant system. Inz Chem Process 2001; 22(2): 251-67.
    • (2001) Inz Chem Process , vol.22 , Issue.2 , pp. 251-267
    • Sosnowski, T.R.1
  • 71
    • 0025307779 scopus 로고
    • Surfactant displaces particles toward the epithelium in airways and alveoli
    • Schürch S, Gehr P, Im Hof V, Geiser M, Green F. Surfactant displaces particles toward the epithelium in airways and alveoli. Respir Physiol 1990; 80(1): 17-32.
    • (1990) Respir Physiol , vol.80 , Issue.1 , pp. 17-32
    • Schürch, S.1    Gehr, P.2    Im Hof, V.3    Geiser, M.4    Green, F.5
  • 72
    • 0029999804 scopus 로고    scopus 로고
    • Airway surfactant, a primary defense barrier: Mechanical and immunological aspects
    • Gehr P, Green FHY, Geiser M, Im Hof V, Lee NM, Schürch S. Airway surfactant, a primary defense barrier: mechanical and immunological aspects. J Aerosol Med 1996; 9(2): 163-18.
    • (1996) J Aerosol Med , vol.9 , Issue.2 , pp. 163-218
    • Gehr, P.1    Green, F.H.Y.2    Geiser, M.3    Im Hof, V.4    Lee, N.M.5    Schürch, S.6
  • 73
    • 84873285996 scopus 로고    scopus 로고
    • Alteration of biophysical activity of pulmonary surfactant by aluminosilicate nanoparticles
    • Kondej D, Sosnowski TR. Alteration of biophysical activity of pulmonary surfactant by aluminosilicate nanoparticles. Inhal Toxicol 2013; 25(2): 77-83.
    • (2013) Inhal Toxicol , vol.25 , Issue.2 , pp. 77-83
    • Kondej, D.1    Sosnowski, T.R.2
  • 74
    • 84892661671 scopus 로고    scopus 로고
    • Physicochemical mechanisms of mineral nanoparticles effects on pulmonary gas/liquid interface studied in model systems
    • Kondej D, Sosnowski TR. Physicochemical mechanisms of mineral nanoparticles effects on pulmonary gas/liquid interface studied in model systems. Physicochem Probl Miner Process 2014; 50(1): 55-67.
    • (2014) Physicochem Probl Miner Process , vol.50 , Issue.1 , pp. 55-67
    • Kondej, D.1    Sosnowski, T.R.2
  • 75
    • 2642528624 scopus 로고    scopus 로고
    • Interaction of deposited aerosol particles with the alveolar liquid layer
    • Grado L, Marijnissen J. Eds. Dordrecht: Kluwer
    • Sosnowski TR, Grado L, Iskandar F, Okuyama K. Interaction of deposited aerosol particles with the alveolar liquid layer. In: Grado L, Marijnissen J. Eds. Optimization of aerosol drug delivery. Dordrecht: Kluwer 2003; pp. 205-16.
    • (2003) Optimization of aerosol drug delivery , pp. 205-216
    • Sosnowski, T.R.1    Grado, L.2    Iskandar, F.3    Okuyama, K.4
  • 76
    • 79953054576 scopus 로고    scopus 로고
    • The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
    • Fang J, Nakamura H, Maeda H. The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv Drug Del Rev 2011; 63(3): 136-51.
    • (2011) Adv Drug Del Rev , vol.63 , Issue.3 , pp. 136-151
    • Fang, J.1    Nakamura, H.2    Maeda, H.3
  • 79
    • 42649125889 scopus 로고    scopus 로고
    • Inhaled nanoparticles-a current review
    • Yang W, Peters JI, Williams III RO. Inhaled nanoparticles-a current review. Int J Pharm 2008; 356 (1-2): 239-47.
    • (2008) Int J Pharm , vol.356 , Issue.1-2 , pp. 239-247
    • Yang, W.1    Peters, J.I.2    Williams, R.O.3
  • 80
    • 58849089005 scopus 로고    scopus 로고
    • Nanoparticle formulations in pulmonary drug delivery
    • Bailey MM, Berkland CJ. Nanoparticle formulations in pulmonary drug delivery. Med Res Rev 2009; 29 (1): 196-212.
    • (2009) Med Res Rev , vol.29 , Issue.1 , pp. 196-212
    • Bailey, M.M.1    Berkland, C.J.2
  • 81
    • 17144472459 scopus 로고    scopus 로고
    • Translocation of inhaled ultrafine particles to the brain
    • Oberdörster G, Sharp Z, Atudorei V, et al. Translocation of inhaled ultrafine particles to the brain. Inhal Toxicol 2004; 16(6-7): 437-45.
    • (2004) Inhal Toxicol , vol.16 , Issue.6-7 , pp. 437-445
    • Oberdörster, G.1    Sharp, Z.2    Atudorei, V.3
  • 82
    • 84872900264 scopus 로고    scopus 로고
    • Particle size distribution of mainstream and exhaled cigarette smoke and predictive deposition in human respiratory tract
    • Sahu SK, Tiwari M, Bhangare RC, Pandit GG. Particle size distribution of mainstream and exhaled cigarette smoke and predictive deposition in human respiratory tract. Aerosol Air Qual Res 2013; 13(1): 324-32.
    • (2013) Aerosol Air Qual Res , vol.13 , Issue.1 , pp. 324-332
    • Sahu, S.K.1    Tiwari, M.2    Bhangare, R.C.3    Pandit, G.G.4
  • 83
    • 84887112201 scopus 로고    scopus 로고
    • Influential parameters on particle concentration and size distribution in the mainstream of e-cigarettes
    • Fuoco FC, Buonanno G, Stabile L, Vigo P. Influential parameters on particle concentration and size distribution in the mainstream of e-cigarettes. Environ Pollut 2014; 184: 523-9.
    • (2014) Environ Pollut , vol.184 , pp. 523-529
    • Fuoco, F.C.1    Buonanno, G.2    Stabile, L.3    Vigo, P.4
  • 84
    • 85027535800 scopus 로고    scopus 로고
    • Predicted lung deposition of electronic cigarette aerosols
    • Sosnowski TR. Predicted lung deposition of electronic cigarette aerosols. J Aerosol Med Pulm Drug Del 2015; 28(3): A28-9.
    • (2015) J Aerosol Med Pulm Drug Del , vol.28 , Issue.3 , pp. A28-A29
    • Sosnowski, T.R.1
  • 85
    • 84941881425 scopus 로고    scopus 로고
    • Electronic cigarettes and vaping: A new challenge in clinical medicine and public health. A literature review
    • article 56
    • Palazzolo DL. Electronic cigarettes and vaping: a new challenge in clinical medicine and public health. A literature review. Front Publ Health 2013; 1: article 56 (20 pages).
    • (2013) Front Publ Health , vol.1
    • Palazzolo, D.L.1
  • 86
    • 84901373578 scopus 로고    scopus 로고
    • E-cigarettes: A scientific review
    • Grana R, Benowitz N, Glantz SA. E-cigarettes: a scientific review. Circulation 2014; 129(19): 1972-86.
    • (2014) Circulation , vol.129 , Issue.19 , pp. 1972-1986
    • Grana, R.1    Benowitz, N.2    Glantz, S.A.3
  • 87
    • 78650175544 scopus 로고    scopus 로고
    • In vitro aerosol characterization of Staccato(®) Loxapine
    • Dinh K, Myers DJ, Glazer M, et al. In vitro aerosol characterization of Staccato(®) Loxapine. Int J Pharm 2011; 403(1-2): 101-8.
    • (2011) Int J Pharm , vol.403 , Issue.1-2 , pp. 101-108
    • Dinh, K.1    Myers, D.J.2    Glazer, M.3
  • 88
    • 84889000300 scopus 로고    scopus 로고
    • Alternative delivery systems for agents to treat acute agitation: Progress to date
    • Nordstrom K, Allen MH. Alternative delivery systems for agents to treat acute agitation: progress to date. Drugs 2013; 73(16): 1783-92.
    • (2013) Drugs , vol.73 , Issue.16 , pp. 1783-1792
    • Nordstrom, K.1    Allen, M.H.2
  • 89
    • 84911471922 scopus 로고    scopus 로고
    • Loxapine inhalation powder (adasuve): A new and innovative formulation of an antipsychotic treatment for agitation
    • Valdes J, Shipley T, Rey JA. Loxapine inhalation powder (adasuve): a new and innovative formulation of an antipsychotic treatment for agitation. Pharm Ther 2014; 39(9): 621-3, 648.
    • (2014) Pharm Ther , vol.39 , Issue.9
    • Valdes, J.1    Shipley, T.2    Rey, J.A.3
  • 90
    • 84906936347 scopus 로고    scopus 로고
    • Inhaled insulin: A breath of fresh air? A review of inhaled insulin
    • Santos CT, Edelman S. Inhaled insulin: a breath of fresh air? A review of inhaled insulin. Clin Ther 2014; 36(8): 1275-89.
    • (2014) Clin Ther , vol.36 , Issue.8 , pp. 1275-1289
    • Santos, C.T.1    Edelman, S.2
  • 91
    • 33750800097 scopus 로고    scopus 로고
    • Implications for occupational exposure to particulate matter
    • Utell MJ, Beckett WS. Implications for occupational exposure to particulate matter. Clin Occup Environ Med 2006; 5(4): 883-93.
    • (2006) Clin Occup Environ Med , vol.5 , Issue.4 , pp. 883-893
    • Utell, M.J.1    Beckett, W.S.2
  • 92
    • 39449124285 scopus 로고    scopus 로고
    • Chronic obstructive pulmonary disease and occupational exposure to silica
    • Rushton L. Chronic obstructive pulmonary disease and occupational exposure to silica. Rev Environ Health 2007; 22(4): 255-72.
    • (2007) Rev Environ Health , vol.22 , Issue.4 , pp. 255-272
    • Rushton, L.1
  • 93
    • 0028907783 scopus 로고
    • Lung particle overload: Implications for occupational exposures to particles
    • Oberdörster G. Lung particle overload: implications for occupational exposures to particles. Regul Toxicol Pharmacol 1995; 21(1): 123-35.
    • (1995) Regul Toxicol Pharmacol , vol.21 , Issue.1 , pp. 123-135
    • Oberdörster, G.1
  • 94
    • 84930740689 scopus 로고    scopus 로고
    • Afrezza inhaled insulin: The fastest-acting FDAapproved insulin on the market has favorable properties
    • Klonoff DC. Afrezza inhaled insulin: the fastest-acting FDAapproved insulin on the market has favorable properties. J Diabetes Sci Technol 2014; 8(6): 1071-3.
    • (2014) J Diabetes Sci Technol , vol.8 , Issue.6 , pp. 1071-1073
    • Klonoff, D.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.