Defects during Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms

Cerebral Cortex

Volumn 26, Issue 6, 2016, Pages 2517-2529

  Bedogni, Francesco ^a   Gigli, Clementina Cobolli ^a,b   Pozzi, Davide ^c   Rossi, Riccardo Lorenzo ^d   Scaramuzza, Linda ^a   Rossetti, Grazisa ^d   Pagani, Massimiliano ^d   Kilstrup Nielsen, Charlotte ^b   Matteoli, Michela ^c,e   Landsberger, Nicoletta ^a,b  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b UNIVERSITY OF INSUBRIA   (Italy)

^c HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^d Istituto Nazionale di Genetica Molecolare   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

Author keywords

Embryonic cerebral cortex development; Intrinsic neuronal excitability; MeCP2 null cortex; Neurological disorders; Transcriptome

Indexed keywords

METHYL CPG BINDING PROTEIN 2; CALCIUM; GLUTAMIC ACID; MECP2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; BRAIN FUNCTION; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FEMALE; HUMAN; MALE; MOUSE; NEOCORTEX; NERVE CELL CULTURE; NEUROLOGIC DISEASE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CELL CULTURE; CELL MOTION; DISEASE COURSE; ELECTROSTIMULATION; EMBRYOLOGY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC TRANSCRIPTION; GENETICS; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY; RETT SYNDROME; TIME FACTOR; VOLTAGE SENSITIVE DYE IMAGING;

ANIMALS; CALCIUM; CELL MOVEMENT; CELLS, CULTURED; CEREBRAL CORTEX; DISEASE PROGRESSION; ELECTRIC STIMULATION; FLUORESCENT ANTIBODY TECHNIQUE; GLUTAMIC ACID; METHYL-CPG-BINDING PROTEIN 2; MICE, KNOCKOUT; NEURONS; RETT SYNDROME; TIME FACTORS; TRANSCRIPTION, GENETIC; VOLTAGE-SENSITIVE DYE IMAGING;

EID: 84974573964     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhv078     Document Type: Article

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