-
1
-
-
0033849777
-
Obesity and insulin resistance
-
Kahn, B. B. & Flier, J. S. Obesity and insulin resistance. J Clin Invest. 106, 473-481 (2000).
-
(2000)
J Clin Invest.
, vol.106
, pp. 473-481
-
-
Kahn, B.B.1
Flier, J.S.2
-
2
-
-
0347985272
-
Obesity-induced inflammatory changes in adipose tissue
-
Wellen, K. E. & Hotamisligil, G. S. Obesity-induced inflammatory changes in adipose tissue. J. Clin. Invest. 112, 1785-1788 (2003).
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1785-1788
-
-
Wellen, K.E.1
Hotamisligil, G.S.2
-
3
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu, H. et al. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J. Clin. Invest. 112, 1821-1830 (2003).
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
-
4
-
-
33845914986
-
Mechanisms linking obesity with cardiovascular disease
-
Van Gaal, L. F., Mertens, I. L. & De Block, C. E. Mechanisms linking obesity with cardiovascular disease. Nature. 444, 875-880 (2006).
-
(2006)
Nature.
, vol.444
, pp. 875-880
-
-
Van Gaal, L.F.1
Mertens, I.L.2
De Block, C.E.3
-
5
-
-
22844437863
-
Endocrine and signaling role of adipose tissue: New perspectives on fat
-
Trayhurn, P. Endocrine and signaling role of adipose tissue: New perspectives on fat. Acta Physiol Scand. 184, 285-293 (2005).
-
(2005)
Acta Physiol Scand.
, vol.184
, pp. 285-293
-
-
Trayhurn, P.1
-
6
-
-
0033562966
-
Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
-
Kaufman, R. J. Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls. Genes Dev. 13, 1211-1233 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 1211-1233
-
-
Kaufman, R.J.1
-
7
-
-
5644231992
-
Endoplasmic reticulum stress links obesity insulin action and type 2 diabetes
-
Ozcan, U. et al. Endoplasmic reticulum stress links obesity insulin action and type 2 diabetes. Science 306, 457-461 (2004).
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
-
8
-
-
79251508007
-
Measurement of the increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals, methods
-
Boden, G. & Merali, S. Measurement of the increase in endoplasmic reticulum stress-related proteins and genes in adipose tissue of obese, insulin-resistant individuals, methods. Enzymol. 489, 67-82 (2011).
-
(2011)
Enzymol.
, vol.489
, pp. 67-82
-
-
Boden, G.1
Merali, S.2
-
9
-
-
84869184022
-
Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue
-
N. Kawasaki, R. et al. Obesity-induced endoplasmic reticulum stress causes chronic inflammation in adipose tissue. Sci. Rep. 2, 799 (2012).
-
(2012)
Sci. Rep.
, vol.2
, pp. 799
-
-
Kawasaki R, N.1
-
10
-
-
0030154323
-
Influence of molecular and chemical chaperones on protein folding
-
Welch, W. J. & Brown, C. R. Influence of molecular and chemical chaperones on protein folding. Cell Stress Chaperones 1(2), 109-15 (1996).
-
(1996)
Cell Stress Chaperones
, vol.1
, Issue.2
, pp. 109-115
-
-
Welch, W.J.1
Brown, C.R.2
-
11
-
-
34249814605
-
Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone
-
Inden, M., Kitamura, Y. et al. Neurodegeneration of mouse nigrostriatal dopaminergic system induced by repeated oral administration of rotenone is prevented by 4-phenylbutyrate, a chemical chaperone. J. Neurochem. 101, 1491-1504 (2007).
-
(2007)
J. Neurochem.
, vol.101
, pp. 1491-1504
-
-
Inden, M.1
Kitamura, Y.2
-
12
-
-
57149117113
-
Role of endoplasmic reticulum stress in acrolein-induced endothelial activation
-
Haberzettl, P., Vladykovskaya, E., Srivastava, S. & Bhatnagar, A. Role of endoplasmic reticulum stress in acrolein-induced endothelial activation. Toxicol. Appl. Pharmacol. 234, 14-24 (2009).
-
(2009)
Toxicol. Appl. Pharmacol.
, vol.234
, pp. 14-24
-
-
Haberzettl, P.1
Vladykovskaya, E.2
Srivastava, S.3
Bhatnagar, A.4
-
13
-
-
77955644910
-
NF-κ B in renal inflammation
-
Ana. Belen, S. et al. NF-κ B in renal inflammation. J Am Soc Nephro. 21(8), 1254-1262 (2010).
-
(2010)
J Am Soc Nephro.
, vol.21
, Issue.8
, pp. 1254-1262
-
-
Ana Belen, S.1
-
14
-
-
84858699864
-
McGuckin. The interplay between endoplasmic reticulum stress and inflammation
-
Hasnain, S. Z. et al. McGuckin. The interplay between endoplasmic reticulum stress and inflammation. Immunol Cell Biol. 90(3), 260-270 (2012).
-
(2012)
Immunol Cell Biol.
, vol.90
, Issue.3
, pp. 260-270
-
-
Hasnain, S.Z.1
-
15
-
-
84896695185
-
Ox-LDL Induces ER Stress and Promotes the adipokines Secretion in 3T3-L1 Adipocytes
-
Chen, Y. Q., Chen, M. J., Wu, Z. H. & Zhao, S. P. Ox-LDL Induces ER Stress and Promotes the adipokines Secretion in 3T3-L1 Adipocytes. Plos one 8(10), 65-65 (2013).
-
(2013)
Plos One
, vol.8
, Issue.10
, pp. 65
-
-
Chen, Y.Q.1
Chen, M.J.2
Wu, Z.H.3
Zhao, S.P.4
-
16
-
-
34548419344
-
Thematic review series: Adipocyte biology. Adipocyte stress: The endoplasmic reticulum and metabolic disease
-
Gregor, M. F. & Hotamisligil, G. S. Thematic review series: Adipocyte biology. Adipocyte stress: The endoplasmic reticulum and metabolic disease. J Lipid Res. 48(9), 1905-1914 (2007).
-
(2007)
J Lipid Res.
, vol.48
, Issue.9
, pp. 1905-1914
-
-
Gregor, M.F.1
Hotamisligil, G.S.2
-
17
-
-
77955411159
-
Tauroursode-oxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women
-
Kars, M. et al. Tauroursode-oxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes 59(8), 1899-1905 (2010).
-
(2010)
Diabetes
, vol.59
, Issue.8
, pp. 1899-1905
-
-
Kars, M.1
-
18
-
-
85030434746
-
I. Increased oxidative stress in obesity and its impact on metabolic syndrome
-
Furukawa, S. et al. I. Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114, 1752-1761 (2004).
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1752-1761
-
-
Furukawa, S.1
-
19
-
-
84894968202
-
The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress
-
Cha, B. H. et al. The role of tauroursodeoxycholic acid on adipogenesis of human adipose-derived stem cells by modulation of ER stress. Biomaterials 35(9), 2851-8 (2014).
-
(2014)
Biomaterials
, vol.35
, Issue.9
, pp. 2851-2858
-
-
Cha, B.H.1
-
20
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in amouse model of type 2 diabetes
-
Ozcan, U. et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in amouse model of type 2 diabetes. Science 313, 1137-1140 (2006).
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
-
21
-
-
20444461628
-
Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: Model of NF-kappaB and map kinase-dependent inflammation in advanced atherosclerosis
-
Li, Y. et al. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: Model of NF-kappaB and map kinase-dependent inflammation in advanced atherosclerosis. J Biol Chem. 280(23), 21763-72 (2005).
-
(2005)
J Biol Chem.
, vol.280
, Issue.23
, pp. 21763-21772
-
-
Li, Y.1
-
22
-
-
0036790413
-
Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications
-
Tabas, I. Consequences of cellular cholesterol accumulation: Basic concepts and physiological implications. J Clin Invest. 110, 905-911 (2002).
-
(2002)
J Clin Invest.
, vol.110
, pp. 905-911
-
-
Tabas, I.1
-
23
-
-
14244269217
-
Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and i kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro
-
Lappas, M., Yee, K. & Permezel, M. Rice GE. Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-kappa B and I kappa B kinase pathway to regulate the release of proinflammatory cytokines from human adipose tissue and skeletal muscle in vitro. Endocrinology 146, 1491-1497 (2005).
-
(2005)
Endocrinology
, vol.146
, pp. 1491-1497
-
-
Lappas, M.1
Yee, K.2
Permezel, M.3
Rice, G.E.4
-
24
-
-
20044387026
-
IKK-beta links inflammation to obesity induced insulin resistance
-
Arkan, M. C. et al. IKK-beta links inflammation to obesity induced insulin resistance. Nat Med. 11, 191-198 (2005).
-
(2005)
Nat Med.
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
-
25
-
-
33645815074
-
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
-
Hu, P., Han, Z., Couvillon, A. D., Kaufman, R. J. & Exton, J. H. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol Cell Biol. 26, 3071-3084 (2006).
-
(2006)
Mol Cell Biol.
, vol.26
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
26
-
-
69849109361
-
Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response
-
Yamazaki, H. et al. Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response. J. Immunol. 183, 1480-1487 (2009).
-
(2009)
J. Immunol.
, vol.183
, pp. 1480-1487
-
-
Yamazaki, H.1
-
27
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil, G. S. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140, 900-917 (2010).
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
28
-
-
8644282751
-
Translational repression mediates activation of nuclear factor kappaB by phosphorylated translation initiation factor 2
-
Deng, J. et al. Translational repression mediates activation of nuclear factor kappaB by phosphorylated translation initiation factor 2. Mol. Cell. Biol. 24, 10161-10168 (2004).
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 10161-10168
-
-
Deng, J.1
|