메뉴 건너뛰기




Volumn 90, Issue 6, 2016, Pages 1154-1163

The Evolution of Genetics: Alzheimer's and Parkinson's Diseases

Author keywords

Alzheimer's disease; Exome sequencing; Genetics; Genome wide association; Parkinson's disease

Indexed keywords

ALZHEIMER DISEASE; CLINICAL RESEARCH; GENE IDENTIFICATION; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; GENETIC DISORDER; GENETIC RISK; GENETICS; HUMAN; HUMAN GENOME; HYPOTHESIS; MOLECULAR GENETICS; PARKINSON DISEASE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; THERAPY; UNCERTAINTY; GENETIC PREDISPOSITION; MEDICAL GENETICS; METHODOLOGY; MUTATION; TRENDS;

EID: 84973915581     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2016.05.040     Document Type: Review
Times cited : (81)

References (63)
  • 1
    • 84894322830 scopus 로고    scopus 로고
    • Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
    • International Parkinson's Disease Genomics Consortium, North American Brain Expression ConsortiumNorth American Brain Expression Consortium
    • Beilina A., Rudenko I.N., Kaganovich A., Civiero L., Chau H., Kalia S.K., Kalia L.V., Lobbestael E., Chia R., Ndukwe K., et al. Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease. Proc. Natl. Acad. Sci. USA 2014, 111:2626-2631. International Parkinson's Disease Genomics Consortium, North American Brain Expression ConsortiumNorth American Brain Expression Consortium.
    • (2014) Proc. Natl. Acad. Sci. USA , vol.111 , pp. 2626-2631
    • Beilina, A.1    Rudenko, I.N.2    Kaganovich, A.3    Civiero, L.4    Chau, H.5    Kalia, S.K.6    Kalia, L.V.7    Lobbestael, E.8    Chia, R.9    Ndukwe, K.10
  • 5
    • 84865176138 scopus 로고    scopus 로고
    • Locus-specific mutation databases for neurodegenerative brain diseases
    • Cruts M., Theuns J., Van Broeckhoven C. Locus-specific mutation databases for neurodegenerative brain diseases. Hum. Mutat. 2012, 33:1340-1344.
    • (2012) Hum. Mutat. , vol.33 , pp. 1340-1344
    • Cruts, M.1    Theuns, J.2    Van Broeckhoven, C.3
  • 9
  • 12
    • 84878682420 scopus 로고    scopus 로고
    • The Genotype-Tissue Expression (GTEx) project
    • The Genotype-Tissue Expression (GTEx) project. Nat. Genet. 2013, 45:580-585. GTEx Consortium.
    • (2013) Nat. Genet. , vol.45 , pp. 580-585
  • 15
    • 84948808791 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases
    • International Parkinson's Disease Genomics Consortium (IPDGC)
    • Guerreiro R., Escott-Price V., Darwent L., Parkkinen L., Ansorge O., Hernandez D.G., Nalls M.A., Clark L., Honig L., Marder K., et al. Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases. Neurobiol. Aging 2015, 38:214.e7-214.e10. International Parkinson's Disease Genomics Consortium (IPDGC).
    • (2015) Neurobiol. Aging , vol.38 , pp. 214.e7-214.e10
    • Guerreiro, R.1    Escott-Price, V.2    Darwent, L.3    Parkkinen, L.4    Ansorge, O.5    Hernandez, D.G.6    Nalls, M.A.7    Clark, L.8    Honig, L.9    Marder, K.10
  • 19
    • 79955484414 scopus 로고    scopus 로고
    • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
    • Alzheimer's Disease Neuroimaging Initiative, CHARGE consortiumCHARGE consortium, EADI1 consortiumEADI1 consortium
    • Hollingworth P., Harold D., Sims R., Gerrish A., Lambert J.-C., Carrasquillo M.M., Abraham R., Hamshere M.L., Pahwa J.S., Moskvina V., et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat. Genet. 2011, 43:429-435. Alzheimer's Disease Neuroimaging Initiative, CHARGE consortiumCHARGE consortium, EADI1 consortiumEADI1 consortium.
    • (2011) Nat. Genet. , vol.43 , pp. 429-435
    • Hollingworth, P.1    Harold, D.2    Sims, R.3    Gerrish, A.4    Lambert, J.-C.5    Carrasquillo, M.M.6    Abraham, R.7    Hamshere, M.L.8    Pahwa, J.S.9    Moskvina, V.10
  • 20
    • 84873486299 scopus 로고    scopus 로고
    • A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease
    • International Parkinson's Disease Genomics Consortium
    • Holmans P., Moskvina V., Jones L., Sharma M., Vedernikov A., Buchel F., Saad M., Bras J.M., Bettella F., Nicolaou N., et al. A pathway-based analysis provides additional support for an immune-related genetic susceptibility to Parkinson's disease. Hum. Mol. Genet. 2013, 22:1039-1049. International Parkinson's Disease Genomics Consortium.
    • (2013) Hum. Mol. Genet. , vol.22 , pp. 1039-1049
    • Holmans, P.1    Moskvina, V.2    Jones, L.3    Sharma, M.4    Vedernikov, A.5    Buchel, F.6    Saad, M.7    Bras, J.M.8    Bettella, F.9    Nicolaou, N.10
  • 21
    • 84931560814 scopus 로고    scopus 로고
    • Convergent genetic and expression data implicate immunity in Alzheimer's disease
    • Convergent genetic and expression data implicate immunity in Alzheimer's disease. Alzheimers Dement. 2015, 11:658-671. International Genomics of Alzheimer's Disease Consortium (IGAP).
    • (2015) Alzheimers Dement. , vol.11 , pp. 658-671
  • 22
    • 79959851714 scopus 로고    scopus 로고
    • A two-stage meta-analysis identifies several new loci for Parkinson's disease
    • A two-stage meta-analysis identifies several new loci for Parkinson's disease. PLoS Genet. 2011, 7:e1002142. International Parkinson's Disease Genomics Consortium (IPDGC), Wellcome Trust Case Control Consortium 2 (WTCCC2)Wellcome Trust Case Control Consortium 2 (WTCCC2).
    • (2011) PLoS Genet. , vol.7 , pp. e1002142
  • 25
    • 84868134823 scopus 로고    scopus 로고
    • Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease
    • International Parkinson's Disease Genomics Consortium (IPDGC), Wellcome Trust Case Control Consortium 2 (WTCCC2)Wellcome Trust Case Control Consortium 2 (WTCCC2)
    • Keller M.F., Saad M., Bras J., Bettella F., Nicolaou N., Simón-Sánchez J., Mittag F., Büchel F., Sharma M., Gibbs J.R., et al. Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. Hum. Mol. Genet. 2012, 21:4996-5009. International Parkinson's Disease Genomics Consortium (IPDGC), Wellcome Trust Case Control Consortium 2 (WTCCC2)Wellcome Trust Case Control Consortium 2 (WTCCC2).
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 4996-5009
    • Keller, M.F.1    Saad, M.2    Bras, J.3    Bettella, F.4    Nicolaou, N.5    Simón-Sánchez, J.6    Mittag, F.7    Büchel, F.8    Sharma, M.9    Gibbs, J.R.10
  • 27
    • 78549264026 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
    • European Alzheimer's Disease Initiative Investigators
    • Lambert J.-C., Heath S., Even G., Campion D., Sleegers K., Hiltunen M., Combarros O., Zelenika D., Bullido M.J., Tavernier B., et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat. Genet. 2009, 41:1094-1099. European Alzheimer's Disease Initiative Investigators.
    • (2009) Nat. Genet. , vol.41 , pp. 1094-1099
    • Lambert, J.-C.1    Heath, S.2    Even, G.3    Campion, D.4    Sleegers, K.5    Hiltunen, M.6    Combarros, O.7    Zelenika, D.8    Bullido, M.J.9    Tavernier, B.10
  • 28
    • 84888317489 scopus 로고    scopus 로고
    • Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
    • European Alzheimer's Disease Initiative (EADI), Genetic and Environmental Risk in Alzheimer's DiseaseGenetic and Environmental Risk in Alzheimer's Disease, Alzheimer's Disease Genetic ConsortiumAlzheimer's Disease Genetic Consortium, Cohorts for Heart and Aging Research in Genomic EpidemiologyCohorts for Heart and Aging Research in Genomic Epidemiology
    • Lambert J.C., Ibrahim-Verbaas C.A., Harold D., Naj A.C., Sims R., Bellenguez C., DeStafano A.L., Bis J.C., Beecham G.W., Grenier-Boley B., et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat. Genet. 2013, 45:1452-1458. European Alzheimer's Disease Initiative (EADI), Genetic and Environmental Risk in Alzheimer's DiseaseGenetic and Environmental Risk in Alzheimer's Disease, Alzheimer's Disease Genetic ConsortiumAlzheimer's Disease Genetic Consortium, Cohorts for Heart and Aging Research in Genomic EpidemiologyCohorts for Heart and Aging Research in Genomic Epidemiology.
    • (2013) Nat. Genet. , vol.45 , pp. 1452-1458
    • Lambert, J.C.1    Ibrahim-Verbaas, C.A.2    Harold, D.3    Naj, A.C.4    Sims, R.5    Bellenguez, C.6    DeStafano, A.L.7    Bis, J.C.8    Beecham, G.W.9    Grenier-Boley, B.10
  • 30
    • 84859339977 scopus 로고    scopus 로고
    • Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database
    • 23andMe Genetic Epidemiology of Parkinson's Disease Consortium, International Parkinson's Disease Genomics ConsortiumInternational Parkinson's Disease Genomics Consortium, Parkinson's Disease GWAS ConsortiumParkinson's Disease GWAS Consortium, Wellcome Trust Case Control Consortium 2)Wellcome Trust Case Control Consortium 2)
    • Lill C.M., Roehr J.T., McQueen M.B., Kavvoura F.K., Bagade S., Schjeide B.-M.M., Schjeide L.M., Meissner E., Zauft U., Allen N.C., et al. Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database. PLoS Genet. 2012, 8:e1002548. 23andMe Genetic Epidemiology of Parkinson's Disease Consortium, International Parkinson's Disease Genomics ConsortiumInternational Parkinson's Disease Genomics Consortium, Parkinson's Disease GWAS ConsortiumParkinson's Disease GWAS Consortium, Wellcome Trust Case Control Consortium 2)Wellcome Trust Case Control Consortium 2).
    • (2012) PLoS Genet. , vol.8 , pp. e1002548
    • Lill, C.M.1    Roehr, J.T.2    McQueen, M.B.3    Kavvoura, F.K.4    Bagade, S.5    Schjeide, B.-M.M.6    Schjeide, L.M.7    Meissner, E.8    Zauft, U.9    Allen, N.C.10
  • 33
    • 84885781056 scopus 로고    scopus 로고
    • Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk
    • IPDGC and GERAD Investigators
    • Moskvina V., Harold D., Russo G., Vedernikov A., Sharma M., Saad M., Holmans P., Bras J.M., Bettella F., Keller M.F., et al. Analysis of genome-wide association studies of Alzheimer disease and of Parkinson disease to determine if these 2 diseases share a common genetic risk. JAMA Neurol. 2013, 70:1268-1276. IPDGC and GERAD Investigators.
    • (2013) JAMA Neurol. , vol.70 , pp. 1268-1276
    • Moskvina, V.1    Harold, D.2    Russo, G.3    Vedernikov, A.4    Sharma, M.5    Saad, M.6    Holmans, P.7    Bras, J.M.8    Bettella, F.9    Keller, M.F.10
  • 36
    • 79951811351 scopus 로고    scopus 로고
    • Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies
    • International Parkinson Disease Genomics Consortium
    • Nalls M.A., Plagnol V., Hernandez D.G., Sharma M., Sheerin U.M., Saad M., Simón-Sánchez J., Schulte C., Lesage S., Sveinbjörnsdóttir S., et al. Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet 2011, 377:641-649. International Parkinson Disease Genomics Consortium.
    • (2011) Lancet , vol.377 , pp. 641-649
    • Nalls, M.A.1    Plagnol, V.2    Hernandez, D.G.3    Sharma, M.4    Sheerin, U.M.5    Saad, M.6    Simón-Sánchez, J.7    Schulte, C.8    Lesage, S.9    Sveinbjörnsdóttir, S.10
  • 37
    • 84939599004 scopus 로고    scopus 로고
    • Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
    • International Parkinson's Disease Genomics Consortium (IPDGC), Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI)Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI), 23andMe23andMe, GenePDGenePD, NeuroGenetics Research Consortium (NGRC)NeuroGenetics Research Consortium (NGRC), Hussman Institute of Human Genomics (HIHG)Hussman Institute of Human Genomics (HIHG), Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE)Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE), North American Brain Expression Consortium (NABEC)North American Brain Expression Consortium (NABEC), United Kingdom Brain Expression Consortium (UKBEC)United Kingdom Brain Expression Consortium (UKBEC), Greek Parkinson's Disease ConsortiumGreek Parkinson's Disease Consortium
    • Nalls M., Pankratz N., Lill C.M., Do C.B., Hernandez D.G., Saad M., DeStefano A.L., Kara E., Bras J., Sharma M., et al. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nat. Genet. 2014, 46:989-993. International Parkinson's Disease Genomics Consortium (IPDGC), Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI)Parkinson's Study Group (PSG) Parkinson's Research: The Organized GENetics Initiative (PROGENI), 23andMe23andMe, GenePDGenePD, NeuroGenetics Research Consortium (NGRC)NeuroGenetics Research Consortium (NGRC), Hussman Institute of Human Genomics (HIHG)Hussman Institute of Human Genomics (HIHG), Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE)Ashkenazi Jewish Dataset Investigator; Cohorts for Health and Aging Research in Genetic Epidemiology (CHARGE), North American Brain Expression Consortium (NABEC)North American Brain Expression Consortium (NABEC), United Kingdom Brain Expression Consortium (UKBEC)United Kingdom Brain Expression Consortium (UKBEC), Greek Parkinson's Disease ConsortiumGreek Parkinson's Disease Consortium, Alzheimer Genetic Analysis GroupAlzheimer Genetic Analysis Group.
    • (2014) Nat. Genet. , vol.46 , pp. 989-993
    • Nalls, M.1    Pankratz, N.2    Lill, C.M.3    Do, C.B.4    Hernandez, D.G.5    Saad, M.6    DeStefano, A.L.7    Kara, E.8    Bras, J.9    Sharma, M.10
  • 38
    • 84892453822 scopus 로고    scopus 로고
    • Genetic comorbidities in Parkinson's disease
    • International Parkinson's Disease Genomics Consortium (IPDGC), Wellcome Trust Case Control Consortium 2 (WTCCC2)Wellcome Trust Case Control Consortium 2 (WTCCC2), North American Brain Expression Consortium (NABEC)North American Brain Expression Consortium (NABEC), United Kingdom Brain Expression Consortium (UKBEC)United Kingdom Brain Expression Consortium (UKBEC)
    • Nalls M.A., Saad M., Noyce A.J., Keller M.F., Schrag A., Bestwick J.P., Traynor B.J., Gibbs J.R., Hernandez D.G., Cookson M.R., et al. Genetic comorbidities in Parkinson's disease. Hum. Mol. Genet. 2014, 23:831-841. International Parkinson's Disease Genomics Consortium (IPDGC), Wellcome Trust Case Control Consortium 2 (WTCCC2)Wellcome Trust Case Control Consortium 2 (WTCCC2), North American Brain Expression Consortium (NABEC)North American Brain Expression Consortium (NABEC), United Kingdom Brain Expression Consortium (UKBEC)United Kingdom Brain Expression Consortium (UKBEC).
    • (2014) Hum. Mol. Genet. , vol.23 , pp. 831-841
    • Nalls, M.A.1    Saad, M.2    Noyce, A.J.3    Keller, M.F.4    Schrag, A.5    Bestwick, J.P.6    Traynor, B.J.7    Gibbs, J.R.8    Hernandez, D.G.9    Cookson, M.R.10
  • 42
    • 58149100151 scopus 로고    scopus 로고
    • Genomewide association study for susceptibility genes contributing to familial Parkinson disease
    • PSG-PROGENI and GenePD Investigators, Coordinators and Molecular Genetic Laboratories
    • Pankratz N., Wilk J.B., Latourelle J.C., DeStefano A.L., Halter C., Pugh E.W., Doheny K.F., Gusella J.F., Nichols W.C., Foroud T., Myers R.H. Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum. Genet. 2009, 124:593-605. PSG-PROGENI and GenePD Investigators, Coordinators and Molecular Genetic Laboratories.
    • (2009) Hum. Genet. , vol.124 , pp. 593-605
    • Pankratz, N.1    Wilk, J.B.2    Latourelle, J.C.3    DeStefano, A.L.4    Halter, C.5    Pugh, E.W.6    Doheny, K.F.7    Gusella, J.F.8    Nichols, W.C.9    Foroud, T.10    Myers, R.H.11
  • 44
    • 82755161902 scopus 로고    scopus 로고
    • The Parkinson Progression Marker Initiative (PPMI)
    • The Parkinson Progression Marker Initiative (PPMI). Prog. Neurobiol. 2011, 95:629-635. Parkinson Progression Marker Initiative.
    • (2011) Prog. Neurobiol. , vol.95 , pp. 629-635
  • 47
    • 0029101491 scopus 로고
    • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
    • Rogaev E.I., Sherrington R., Rogaeva E.A., Levesque G., Ikeda M., Liang Y., Chi H., Lin C., Holman K., Tsuda T., et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 1995, 376:775-778.
    • (1995) Nature , vol.376 , pp. 775-778
    • Rogaev, E.I.1    Sherrington, R.2    Rogaeva, E.A.3    Levesque, G.4    Ikeda, M.5    Liang, Y.6    Chi, H.7    Lin, C.8    Holman, K.9    Tsuda, T.10
  • 48
    • 78651110778 scopus 로고    scopus 로고
    • Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population
    • French Parkinson's Disease Genetics Study Group
    • Saad M., Lesage S., Saint-Pierre A., Corvol J.-C., Zelenika D., Lambert J.-C., Vidailhet M., Mellick G.D., Lohmann E., Durif F., et al. Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. Hum. Mol. Genet. 2011, 20:615-627. French Parkinson's Disease Genetics Study Group.
    • (2011) Hum. Mol. Genet. , vol.20 , pp. 615-627
    • Saad, M.1    Lesage, S.2    Saint-Pierre, A.3    Corvol, J.-C.4    Zelenika, D.5    Lambert, J.-C.6    Vidailhet, M.7    Mellick, G.D.8    Lohmann, E.9    Durif, F.10
  • 50
    • 16044373524 scopus 로고    scopus 로고
    • Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
    • Scheuner D., Eckman C., Jensen M., Song X., Citron M., Suzuki N., Bird T.D., Hardy J., Hutton M., Kukull W., et al. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat. Med. 1996, 2:864-870.
    • (1996) Nat. Med. , vol.2 , pp. 864-870
    • Scheuner, D.1    Eckman, C.2    Jensen, M.3    Song, X.4    Citron, M.5    Suzuki, N.6    Bird, T.D.7    Hardy, J.8    Hutton, M.9    Kukull, W.10
  • 51
    • 77952307991 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic loci associated with Alzheimer disease
    • CHARGE Consortium, GERAD1 ConsortiumGERAD1 Consortium, EADI1 ConsortiumEADI1 Consortium
    • Seshadri S., Fitzpatrick A.L., Ikram M.A., DeStefano A.L., Gudnason V., Boada M., Bis J.C., Smith A.V., Carassquillo M.M., Lambert J.C., et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA 2010, 303:1832-1840. CHARGE Consortium, GERAD1 ConsortiumGERAD1 Consortium, EADI1 ConsortiumEADI1 Consortium.
    • (2010) JAMA , vol.303 , pp. 1832-1840
    • Seshadri, S.1    Fitzpatrick, A.L.2    Ikram, M.A.3    DeStefano, A.L.4    Gudnason, V.5    Boada, M.6    Bis, J.C.7    Smith, A.V.8    Carassquillo, M.M.9    Lambert, J.C.10
  • 56
    • 4644295844 scopus 로고    scopus 로고
    • Parkinson's disease and dementia with Lewy bodies: a difference in dose?
    • Singleton A., Gwinn-Hardy K. Parkinson's disease and dementia with Lewy bodies: a difference in dose?. Lancet 2004, 364:1105-1107.
    • (2004) Lancet , vol.364 , pp. 1105-1107
    • Singleton, A.1    Gwinn-Hardy, K.2
  • 57
    • 84856024666 scopus 로고    scopus 로고
    • A generalizable hypothesis for the genetic architecture of disease: pleomorphic risk loci
    • Singleton A., Hardy J. A generalizable hypothesis for the genetic architecture of disease: pleomorphic risk loci. Hum. Mol. Genet. 2011, 20(R2):R158-R162.
    • (2011) Hum. Mol. Genet. , vol.20 , Issue.R2 , pp. R158-R162
    • Singleton, A.1    Hardy, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.