-
1
-
-
65949104586
-
Genomewide Association Studies and Human Disease
-
doi:10.1056/NEJMra0808700
-
Hardy J, Singleton A, (2009) Genomewide Association Studies and Human Disease. New England Journal of Medicine 360: 1759-1768 doi:10.1056/NEJMra0808700.
-
(2009)
New England Journal of Medicine
, vol.360
, pp. 1759-1768
-
-
Hardy, J.1
Singleton, A.2
-
2
-
-
58149100151
-
Genomewide association study for susceptibility genes contributing to familial Parkinson disease
-
doi:10.1007/s00439-008-0582-9
-
Pankratz N, Wilk JB, Latourelle JC, DeStefano AL, Halter C, et al. (2009) Genomewide association study for susceptibility genes contributing to familial Parkinson disease. Hum Genet 124: 593-605 doi:10.1007/s00439-008-0582-9.
-
(2009)
Hum Genet
, vol.124
, pp. 593-605
-
-
Pankratz, N.1
Wilk, J.B.2
Latourelle, J.C.3
DeStefano, A.L.4
Halter, C.5
-
3
-
-
70549084415
-
Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease
-
doi:ng.485 [pii] 10.1038/ng.485
-
Satake W, Nakabayashi Y, Mizuta I, Hirota Y, Ito C, et al. (2009) Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease. Nat Genet 41: 1303-1307 doi:ng.485 [pii] 10.1038/ng.485.
-
(2009)
Nat Genet
, vol.41
, pp. 1303-1307
-
-
Satake, W.1
Nakabayashi, Y.2
Mizuta, I.3
Hirota, Y.4
Ito, C.5
-
4
-
-
70549088602
-
Genome-wide association study reveals genetic risk underlying Parkinson's disease
-
doi:ng.487 [pii] 10.1038/ng.487
-
Simon-Sanchez J, Schulte C, Bras JM, Sharma M, Gibbs JR, et al. (2009) Genome-wide association study reveals genetic risk underlying Parkinson's disease. Nat Genet 41: 1308-1312 doi:ng.487 [pii] 10.1038/ng.487.
-
(2009)
Nat Genet
, vol.41
, pp. 1308-1312
-
-
Simon-Sanchez, J.1
Schulte, C.2
Bras, J.M.3
Sharma, M.4
Gibbs, J.R.5
-
5
-
-
79959841853
-
Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease
-
doi:10.1371/journal.pgen.1002141 PGENETICS-D-11-00444 [pii]
-
Do CB, Tung JY, Dorfman E, Kiefer AK, Drabant EM, et al. (2011) Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. PLoS Genet 7: e1002141 doi:10.1371/journal.pgen.1002141 PGENETICS-D-11-00444 [pii].
-
(2011)
PLoS Genet
, vol.7
-
-
Do, C.B.1
Tung, J.Y.2
Dorfman, E.3
Kiefer, A.K.4
Drabant, E.M.5
-
6
-
-
79951811351
-
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies
-
International Parkinson Disease Genomics Consortium, doi:S0140-6736(10)62345-8 [pii] 10.1016/S0140-6736(10)62345-8
-
International Parkinson Disease Genomics Consortium, Nalls MA, Plagnol V, Hernandez DG, Sharma M, et al. (2011) Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet 377: 641-649 doi:S0140-6736(10)62345-8 [pii] 10.1016/S0140-6736(10)62345-8.
-
(2011)
Lancet
, vol.377
, pp. 641-649
-
-
Nalls, M.A.1
Plagnol, V.2
Hernandez, D.G.3
Sharma, M.4
-
7
-
-
79959851714
-
A two-stage meta-analysis identifies several new loci for Parkinson's disease
-
International Parkinson's Disease Genomics Consortium, Wellcome Trust Case Control Consortium, doi:10.1371/journal.pgen.1002142 PGENETICS-D-11-00446 [pii]
-
International Parkinson's Disease Genomics Consortium, Wellcome Trust Case Control Consortium, (2011) A two-stage meta-analysis identifies several new loci for Parkinson's disease. PLoS Genet 7: e1002142 doi:10.1371/journal.pgen.1002142 PGENETICS-D-11-00446 [pii].
-
(2011)
PLoS Genet
, vol.7
-
-
-
8
-
-
78651110778
-
Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population
-
doi:ddq497 [pii] 10.1093/hmg/ddq497
-
Saad M, Lesage S, Saint-Pierre A, Corvol JC, Zelenika D, et al. (2011) Genome-wide association study confirms BST1 and suggests a locus on 12q24 as the risk loci for Parkinson's disease in the European population. Hum Mol Genet 20: 615-627 doi:ddq497 [pii] 10.1093/hmg/ddq497.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 615-627
-
-
Saad, M.1
Lesage, S.2
Saint-Pierre, A.3
Corvol, J.C.4
Zelenika, D.5
-
9
-
-
84856024666
-
A generalizable hypothesis for the genetic architecture of disease: pleomorphic risk loci
-
doi:10.1093/hmg/ddr358
-
Singleton A, Hardy J, (2011) A generalizable hypothesis for the genetic architecture of disease: pleomorphic risk loci. Human Molecular Genetics 20: R158-R162 doi:10.1093/hmg/ddr358.
-
(2011)
Human Molecular Genetics
, vol.20
-
-
Singleton, A.1
Hardy, J.2
-
10
-
-
77956876046
-
Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study
-
doi:10.1016/S1474-4422(10)70184-8
-
Laaksovirta H, Peuralinna T, Schymick JC, Scholz SW, Lai S-L, et al. (2010) Chromosome 9p21 in amyotrophic lateral sclerosis in Finland: a genome-wide association study. Lancet Neurol 9: 978-985 doi:10.1016/S1474-4422(10)70184-8.
-
(2010)
Lancet Neurol
, vol.9
, pp. 978-985
-
-
Laaksovirta, H.1
Peuralinna, T.2
Schymick, J.C.3
Scholz, S.W.4
Lai, S.-L.5
-
11
-
-
33750467600
-
Application of genome-wide single nucleotide polymorphism typing: simple association and beyond
-
doi:10.1371/journal.pgen.0020150
-
Gibbs JR, Singleton A, (2006) Application of genome-wide single nucleotide polymorphism typing: simple association and beyond. PLoS Genet 2: e150 doi:10.1371/journal.pgen.0020150.
-
(2006)
PLoS Genet
, vol.2
-
-
Gibbs, J.R.1
Singleton, A.2
-
12
-
-
80054837386
-
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
-
doi:10.1016/j.neuron.2011.09.010
-
Renton AE, Majounie E, Waite A, Simón-Sánchez J, Rollinson S, et al. (2011) A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 72: 257-268 doi:10.1016/j.neuron.2011.09.010.
-
(2011)
Neuron
, vol.72
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
Simón-Sánchez, J.4
Rollinson, S.5
-
13
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
doi:S0896-6273(11)00828-2 [pii] 10.1016/j.neuron.2011.09.011
-
DeJesus-Hernandez M, Mackenzie IR, Boeve BF, Boxer AL, Baker M, et al. (2011) Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 72: 245-256 doi:S0896-6273(11)00828-2 [pii] 10.1016/j.neuron.2011.09.011.
-
(2011)
Neuron
, vol.72
, pp. 245-256
-
-
DeJesus-Hernandez, M.1
Mackenzie, I.R.2
Boeve, B.F.3
Boxer, A.L.4
Baker, M.5
-
14
-
-
0034049691
-
Familial aggregation of Parkinson's disease in a Finnish population
-
Autere JM, Moilanen JS, Myllyla VV, Majamaa K, (2000) Familial aggregation of Parkinson's disease in a Finnish population. J Neurol Neurosurg Psychiatry 69: 107-109.
-
(2000)
J Neurol Neurosurg Psychiatry
, vol.69
, pp. 107-109
-
-
Autere, J.M.1
Moilanen, J.S.2
Myllyla, V.V.3
Majamaa, K.4
-
15
-
-
0035075874
-
Complex segregation analysis of Parkinson's disease in the Finnish population
-
Moilanen JS, Autere JM, Myllyla VV, Majamaa K, (2001) Complex segregation analysis of Parkinson's disease in the Finnish population. Hum Genet 108: 184-189.
-
(2001)
Hum Genet
, vol.108
, pp. 184-189
-
-
Moilanen, J.S.1
Autere, J.M.2
Myllyla, V.V.3
Majamaa, K.4
-
16
-
-
0036091503
-
Familial aggregation of Parkinson disease: a comparative study of early-onset and late-onset disease
-
doi:noc10257 [pii]
-
Payami H, Zareparsi S, James D, Nutt J, (2002) Familial aggregation of Parkinson disease: a comparative study of early-onset and late-onset disease. Arch Neurol 59: 848-850 doi:noc10257 [pii].
-
(2002)
Arch Neurol
, vol.59
, pp. 848-850
-
-
Payami, H.1
Zareparsi, S.2
James, D.3
Nutt, J.4
-
17
-
-
31744435871
-
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies
-
doi:10.1038/ng1706
-
Skol AD, Scott LJ, Abecasis GR, Boehnke M, (2006) Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies. Nat Genet 38: 209-213 doi:10.1038/ng1706.
-
(2006)
Nat Genet
, vol.38
, pp. 209-213
-
-
Skol, A.D.1
Scott, L.J.2
Abecasis, G.R.3
Boehnke, M.4
-
18
-
-
63449140483
-
Measures of autozygosity in decline: globalization, urbanization, and its implications for medical genetics
-
doi:10.1371/journal.pgen.1000415
-
Nalls MA, Simon-Sanchez J, Gibbs JR, Paisan-Ruiz C, Bras JT, et al. (2009) Measures of autozygosity in decline: globalization, urbanization, and its implications for medical genetics. PLoS Genet 5: e1000415 doi:10.1371/journal.pgen.1000415.
-
(2009)
PLoS Genet
, vol.5
-
-
Nalls, M.A.1
Simon-Sanchez, J.2
Gibbs, J.R.3
Paisan-Ruiz, C.4
Bras, J.T.5
-
19
-
-
70350231628
-
Genotype Imputation
-
doi:10.1146/annurev.genom.9.081307.164242
-
Li Y, Willer C, Sanna S, Abecasis G, (2009) Genotype Imputation. Annu Rev Genomics Hum Genet 10: 387-406 doi:10.1146/annurev.genom.9.081307.164242.
-
(2009)
Annu Rev Genomics Hum Genet
, vol.10
, pp. 387-406
-
-
Li, Y.1
Willer, C.2
Sanna, S.3
Abecasis, G.4
-
20
-
-
78049314943
-
A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses
-
doi:10.1016/S0140-6736(10)61267-6
-
Ripatti S, Tikkanen E, Orho-Melander M, Havulinna AS, Silander K, et al. (2010) A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses. Lancet 376: 1393-1400 doi:10.1016/S0140-6736(10)61267-6.
-
(2010)
Lancet
, vol.376
, pp. 1393-1400
-
-
Ripatti, S.1
Tikkanen, E.2
Orho-Melander, M.3
Havulinna, A.S.4
Silander, K.5
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