Ranolazine improves oxidative stress and mitochondrial function in the atrium of acetylcholine-CaCl2 induced atrial fibrillation rats

Life Sciences

Volumn 156, Issue , 2016, Pages 7-14

  Zou, Deling ^a   Geng, Ning ^a   Chen, Yanli ^a   Ren, Li ^a   Liu, Xingli ^a   Wan, Jiye ^a   Guo, Sicong ^a   Wang, Shaojun ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Akt mTOR; Atrial fibrillation; Mitochondrial function; Ranolazine

Indexed keywords

ACETYLCHOLINE; ADENOSINE TRIPHOSPHATE; ANTIARRHYTHMIC AGENT; ANTIOXIDANT; BETA ACTIN; CALCIUM CHLORIDE; CASPASE 3; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE; MAMMALIAN TARGET OF RAPAMYCIN; MANGANESE SUPEROXIDE DISMUTASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; RANOLAZINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; UBIQUINOL CYTOCHROME C REDUCTASE; XANTHINE OXIDASE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; APOPTOSIS; ARTICLE; BLOOD PRESSURE MONITORING; CONTROLLED STUDY; ELECTROCARDIOGRAM; ENZYME ACTIVITY; EXPERIMENTAL ATRIAL FIBRILLATION; HEART ATRIUM; HEART BEAT; HEART HEMODYNAMICS; HEART MITOCHONDRION; HEART PROTECTION; HISTOLOGY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; P WAVE; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TUNEL ASSAY; WESTERN BLOTTING; ANIMAL; ATRIAL FIBRILLATION; DRUG EFFECTS; HEMODYNAMICS; METABOLISM; MITOCHONDRION; PATHOLOGY; SPRAGUE DAWLEY RAT;

ACETYLCHOLINE; ANIMALS; APOPTOSIS; ATRIAL FIBRILLATION; CALCIUM CHLORIDE; HEART ATRIA; HEMODYNAMICS; MALE; MITOCHONDRIA; OXIDATIVE STRESS; PROTO-ONCOGENE PROTEINS C-AKT; RANOLAZINE; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84973867060     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2016.05.026     Document Type: Article

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