Clinical significance of PD-L1 and PD-L2 copy number gains in non-small-cell lung cancer

Oncotarget

Volumn 7, Issue 22, 2016, Pages 32113-32128

  Inoue, Yusuke ^a   Yoshimura, Katsuhiro ^a   Mori, Kazutaka ^a   Kurabe, Nobuya ^a   Kahyo, Tomoaki ^a   Mori, Hiroki ^b   Kawase, Akikazu ^a   Tanahashi, Masayuki ^c   Ogawa, Hiroshi ^c   Inui, Naoki ^a   Funai, Kazuhito ^a   Shinmura, Kazuya ^a   Niwa, Hiroshi ^c   Suda, Takafumi ^a   Sugimura, Haruhiko ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b HAMAMATSU MEDICAL CENTER   (Japan)

^c Seirei Mikatahara Hospital   (Japan)

Author keywords

Amplification; Copy number; Non small cell lung cancer; PD L1; PD L2

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; JANUS KINASE 2; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 LIGAND 2; CD274 PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; JAK2 PROTEIN, HUMAN; PDCD1LG2 PROTEIN, HUMAN; TUMOR MARKER;

ADJUVANT THERAPY; ADULT; AGED; ARTICLE; CANCER CELL; CANCER PATIENT; CANCER PROGNOSIS; CANCER SURVIVAL; CELL INFILTRATION; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE AMPLIFICATION; GENE DOSAGE; GENOMICS; GOLD STANDARD; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCOMPETENT CELL; JANUS KINASE 2 GENE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; NON SMALL CELL LUNG CANCER; PD L1 GENE; PD L2 GENE; POLYSOME; PREVALENCE; PROTEIN EXPRESSION; REFERENCE VALUE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SMOKING; ADJUVANT CHEMOTHERAPY; CLINICAL TRIAL; COPY NUMBER VARIATION; GENETIC PREDISPOSITION; GENETICS; JAPAN; KAPLAN MEIER METHOD; LUNG RESECTION; LUNG TUMOR; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; PATHOLOGY; PHENOTYPE; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; RISK FACTOR; SECONDARY; STATISTICAL MODEL; TIME FACTOR; TREATMENT OUTCOME; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; B7-H1 ANTIGEN; BIOMARKERS, TUMOR; CARCINOMA, NON-SMALL-CELL LUNG; CHEMOTHERAPY, ADJUVANT; DNA COPY NUMBER VARIATIONS; FEMALE; GENE AMPLIFICATION; GENE DOSAGE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; JANUS KINASE 2; JAPAN; KAPLAN-MEIER ESTIMATE; LOGISTIC MODELS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PHENOTYPE; PNEUMONECTOMY; PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN; PROPORTIONAL HAZARDS MODELS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RETROSPECTIVE STUDIES; RISK FACTORS; SMOKING; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84973548642     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8528     Document Type: Article

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