Variation of DNA Fragmentation Levels during Density Gradient Sperm Selection for Assisted Reproduction Techniques

Medicine (United States)

Volumn 95, Issue 20, 2016, Pages

  Muratori, Monica ^a   Tarozzi, Nicoletta ^b   Cambi, Marta ^a   Boni, Luca ^a   Iorio, Anna Lisa ^a   Passaro, Claudia ^a   Luppino, Benedetta ^c   Nadalini, Marco ^b   Marchiani, Sara ^a   Tamburrino, Lara ^a   Forti, Gianni ^a   Maggi, Mario ^a   Baldi, Elisabetta ^a   Borini, Andrea ^b  

^a UNIVERSITY OF FLORENCE   (Italy)

^b Tecnobios Procreazione   (Italy)

^c CAREGGI UNIVERSITY HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BODY MASS; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; DNA FRAGMENTATION; FEMALE; FERTILIZATION IN VITRO; HUMAN; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; MALE; PREGNANCY; PREGNANCY OUTCOME; PREGNANCY RATE; PRIORITY JOURNAL; PROSPECTIVE STUDY; TUNEL ASSAY; INFERTILITY, FEMALE; INFERTILITY, MALE; RECEIVER OPERATING CHARACTERISTIC; SPERMATOZOON;

ADULT; CENTRIFUGATION, DENSITY GRADIENT; DNA FRAGMENTATION; FEMALE; HUMANS; INFERTILITY, FEMALE; INFERTILITY, MALE; MALE; PREGNANCY; PREGNANCY RATE; PROSPECTIVE STUDIES; ROC CURVE; SPERM INJECTIONS, INTRACYTOPLASMIC; SPERMATOZOA;

EID: 84973520078     PISSN: 00257974     EISSN: 15365964     Source Type: Journal    
DOI: 10.1097/MD.0000000000003624     Document Type: Article

References (45)

1. Williams C, Sutcliffe A. Infant outcomes of assisted reproduction. Early Hum Dev. 2009;85:673-677.
2. Kupka MS, Ferraretti AP, de Mouzon J, et al. European IVFMonitoring Consortium, for the European Society of Human Reproduction and Embryology. Assisted reproductive technology in Europe, 2010: results generated from European registers by ESHRE. Hum Reprod. 2014;29:2099-2113.
3. Morrell JM, Moffatt O, Sakkas D, et al. Reduced senescence and retained nuclear DNA integrity in human spermatozoa prepared by density gradient centrifugation. J Assist Reprod Genet. 2004;21:217-222.
4. Sellami A, Chakroun N, Ben Zarrouk S, et al. Assessment of chromatin maturity in human spermatozoa: useful aniline blue assay for routine diagnosis of male infertility. Adv Urol. 2013;2013:578631.
5. Henkel RR, Schill WB. Sperm preparation for ART. Reprod Biol Endocrinol. 2003;1:108.
6. Gomez E, Aitken J. Impact of in vitro fertilization culture media on peroxidative damage to human spermatozoa. Fertil Steril. 1996;65:880-882.
7. Tremellen K. Oxidative stress and male infertility-A clinical perspective. Hum Reprod Update. 2008;14:243-258.
8. Lewis SE. Is sperm evaluation useful in predicting human fertility? Reproduction. 2007;134:31-40.
9. Muratori M, Marchiani S, Tamburrino L, et al. Markers of human sperm functions in the ICSI era. Front Biosci. 2011;16:1344-1363.
10. Ménézo Y, Dale B, Cohen M. DNA damage and repair in human oocytes and embryos: A review. Zygote. 2010;18:357-365.
11. Gavriliouk D, Aitken RJ. Damage to sperm DNA mediated by reactive oxygen species: its impact on human reproduction and the health trajectory of offspring. Adv Exp Med Biol. 2015;868:23-47.
12. Borini A, Tarozzi N, Bizzaro D, et al. Sperm DNA fragmentation: paternal effect on early post-implantation embryo development in ART. Hum Reprod. 2006;21:2876-2881.
13. Tarozzi N, Bizzaro D, Flamigni C, et al. Clinical relevance of sperm DNA damage in assisted reproduction. Reprod Biomed Online. 2007;14:746-757.
14. Tamburrino L, Marchiani S, Montoya M, et al. Mechanisms and clinical correlates of sperm DNA damage. Asian J Androl. 2012;14:24-31.
15. Zhao J, Zhang Q, Wang Y, et al. Whether sperm deoxyribonucleic acid fragmentation has an effect on pregnancy and miscarriage after in vitro fertilization/intracytoplasmic sperm injection: A systematic review and meta-Analysis. Fertil Steril. 2014;102:998-1005.e8.
16. Osman A, Alsomait H, Seshadri S, et al. The effect of sperm DNA fragmentation on live birth rate after IVF or ICSI: A systematic review and meta-Analysis. Reprod Biomed Online. 2015;30:120-127.
17. Fernández-Gonzalez R, Moreira PN, Pérez-Crespo M, et al. Longterm effects of mouse intracytoplasmic sperm injection with DNAfragmented sperm on health and behavior of adult offspring. Biol Reprod. 2008;78:761-772.
18. Parmegiani L, Cognigni GE, Filicori M. Sperm selection: effect on sperm DNA quality. Adv Exp Med Biol. 2014;791:151-172.
19. Zini A, Mak V, Phang D, et al. Potential adverse effect of semen processing on human sperm deoxyribonucleic acid integrity. Fertil Steril. 1999;72:496-499.
20. Zini A, Nam RK, Mak V, et al. Influence of initial semen quality on the integrity of human sperm DNA following semen processing. Fertil Steril. 2000;74:824-827.
21. Aitken RJ, De Iuliis GN, Finnie JM, et al. Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria. Hum Reprod. 2010;25:2415-2426.
22. Aitken RJ, Finnie JM, Muscio L, et al. Potential importance of transition metals in the induction of DNA damage by sperm preparation media. Hum Reprod. 2014;29:2136-2217.
23. Stevanato J, Bertolla RP, Barradas V, et al. Semen processing by density gradient centrifugation does not improve sperm apoptotic deoxyribonucleic acid fragmentation rates. Fertil Steril. 2008;90:889-890.
24. World Health Organization. Laboratory manual for the examination and processing of human semen. Geneva: WHO Press; 2010.
25. Borini A, Bonu MA, Coticchio G, et al. Pregnancies and births after oocyte cryopreservation. Fertil Steril. 2004;82:601-605.
26. Borini A, Lagalla C, Sciajno R, et al. Artificial reproductive technology achievements for optimizing embryo quality. Ann N Y Acad Sci. 2004;1034:252-261.
27. Muratori M, Tamburrino L, Tocci V, et al. Small variations in crucial steps of TUNEL assay coupled to flow cytometry greatly affect measures of sperm DNA fragmentation. J Androl. 2010;31:336-345.
28. Muratori M, Marchiani S, Tamburrino L, et al. Nuclear staining identifies two populations of human sperm with different DNA fragmentation extent and relationship with semen parameters. Hum Reprod. 2008;23:1035-1043.
29. Marchiani S, Tamburrino L, Maoggi A, et al. Characterization of M540 bodies in human semen: evidence that they are apoptotic bodies. Mol Hum Reprod. 2007;13:621-631.
30. Marchiani S, Tamburrino L, Olivito B, et al. Characterization and sorting of flow cytometric populations in human semen. Andrology. 2014;2:394-401.
31. Marchiani S, Tamburrino L, Giuliano L, et al. Sumo1-ylation of human spermatozoa and its relationship with semen quality. Int J Androl. 2011;34:581-593.
32. Muratori M, Tamburrino L, Marchiani S, et al. Investigation on the origin of sperm DNA fragmentation: role of apoptosis, immaturity and oxidative stress. Mol Med. 2015;21:109-122.
33. Mitchell LA, De Iuliis GN, Aitken RJ. The TUNEL assay consistently underestimates DNA damage in human spermatozoa and is influenced by DNA compaction and cell vitality: development of an improved methodology. Int J Androl. 2011;34:2-13.
34. Shekarriz M, DeWire DM, Thomas AJ Jr et al. A method of human semen centrifugation to minimize the iatrogenic sperm injuries caused by reactive oxygen species. Eur Urol. 1995;28:31-35.
35. Broekmans FJ, Klinkert ER. Female age in ART: when to stop? Gynecol Obstet Invest. 2004;58:225-234.
36. Moragianni VA, Jones SM, Ryley DA. The effect of body mass index on the outcomes of first assisted reproductive technology cycles. Fertil Steril. 2012;98:102-108.
37. Sunkara SK, Khalaf Y, Maheshwari A, et al. Association between response to ovarian stimulation and miscarriage following IVF: An analysis of 124 351 IVF pregnancies. Hum Reprod. 2014;29:1218-1224.
38. Dain L, Auslander R, Dirnfeld M. The effect of paternal age on assisted reproduction outcome. Fertil Steril. 2011;95:1-8.
39. Bungum M, Spano M, Humaidan P, et al. Sperm chromatin structure assay parameters measured after density gradient centrifugation are not predictive for the outcome of ART. Hum Reprod. 2008;23:4-10.
40. Simon L, Brunborg G, Stevenson M, et al. Clinical significance of sperm DNA damage in assisted reproduction outcome. Hum Reprod. 2010;25:1594-1608.
41. Simon L, Lutton D, McManus J, et al. Sperm DNA damage measured by the alkaline Comet assay as an independent predictor of male infertility and in vitro fertilization success. Fertil Steril. 2011;95:652-657.
42. Campbell JM, Lane M, Owens JA, et al. Paternal obesity negatively affects male fertility and assisted reproduction outcomes: A systematic review and meta-Analysis. Reprod Biomed Online. 2015;31: 593-604.
43. Le W, Su SH, Shi LH, et al. Effect of male body mass index on clinical outcomes following assisted reproductive technology: A meta-Analysis. Andrologia. 2016;48:406-424.
44. Merhi ZO, Keltz J, Zapantis A, et al. Male adiposity impairs clinical pregnancy rate by in vitro fertilization without affecting day 3 embryo quality. Obesity (Silver Spring). 2013;21: 1608-1612.
45. Petersen GL, Schmidt L, Pinborg A, et al. The influence of female and male body mass index on live births after assisted reproductive technology treatment: A nationwide register-based cohort study. Fertil Steril. 2013;99:1654-1662.