Influence of initial semen quality on the integrity of human sperm DNA following semen processing

Fertility and Sterility

Volumn 74, Issue 4, 2000, Pages 824-827

  Zini, Armand ^a   Nam, Robert K ^b   Mak, Victor ^a   Phang, Donna ^b   Jarvi, Keith ^b  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

Male factor infertility; Semen processing; Sperm DNA; Sperm motility

Indexed keywords

ACRIDINE ORANGE;

ARTICLE; CLINICAL ARTICLE; DENSITY GRADIENT CENTRIFUGATION; DNA DAMAGE; DNA INTEGRATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MALE; MALE INFERTILITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEMEN ANALYSIS; SPERMATOZOON MOTILITY; STATISTICAL ANALYSIS; UNIVERSITY HOSPITAL;

ACRIDINE ORANGE; ADULT; CENTRIFUGATION, DENSITY GRADIENT; DNA; FLOW CYTOMETRY; HUMAN; MALE; OBSERVATION; PROSPECTIVE STUDIES; SEMEN; SEMEN PRESERVATION; SPERM MOTILITY;

EID: 0033800244     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(00)01495-3     Document Type: Article

References (4)

1. Aitken R.J., Clarkson J.S. Significance of reactive oxygen species and antioxidants in defining the efficacy of sperm preparation techniques. J Androl. 9:1988;367-376.
2. Zini A., Mak V., Phang D., Jarvi K. Potential adverse effect of semen processing on human sperm DNA integrity. Fertil Steril. 72:1999;496-499.
3. Aitken R.J., Gordon E., Harkiss D., Twigg J.P., Milne P., Jennings Z., et al. Relative impact of oxidative stress on the functional competence and genomic integrity of human spermatozoa. Biol Reprod. 59:1998;1037-1046.
4. Twigg J.P., Irvine D.S., Aitken R.J. Oxidative damage to DNA in human spermatozoa does not preclude pronucleus formation at intracytoplasmic sperm injection. Hum Reprod. 13:1998;1864-1871.