Clinical relevance of sperm DNA damage in assisted reproduction

Reproductive BioMedicine Online

Volumn 14, Issue 6, 2007, Pages 746-757

  Tarozzi, Nicoletta ^a   Bizzaro, Davide ^b   Flamigni, Carlo ^c   Borini, Andrea ^a  

^a Tecnobios Procreazione   (Italy)

^b UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Assisted reproduction outcome; Diagnosis DNA fragmentation; Human spermatozoa; Male infertility; Treatment protocols

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CELL DNA; CREATINE KINASE; DNA FRAGMENT; DNA TOPOISOMERASE (ATP HYDROLYSING); ENDONUCLEASE; FAS ANTIGEN; FAS LIGAND; FREE RADICAL; GENOMIC DNA; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; LACTATE DEHYDROGENASE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN STRUCTURE; CHROMOSOME DELETION Y; COMET ASSAY; DNA DAMAGE; DNA STRAND BREAKAGE; DRUG EFFICACY; ENZYME ACTIVATION; ENZYME ACTIVITY; EPIGENETICS; FERTILIZATION IN VITRO; HUMAN; INFERTILITY THERAPY; INTERMETHOD COMPARISON; INTRACYTOPLASMIC SPERM INJECTION; INTRAUTERINE INSEMINATION; MALE INFERTILITY; NICK END LABELING; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PREGNANCY RATE; PREIMPLANTATION EMBRYO; PROTEIN FUNCTION; REVIEW; SENSITIVITY AND SPECIFICITY; SPERMATOGENESIS; SPERMATOZOON ABNORMALITY; TREATMENT FAILURE; TREATMENT OUTCOME;

EID: 34250714915     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1472-6483(10)60678-5     Document Type: Review

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