메뉴 건너뛰기




Volumn 17, Issue 4, 2015, Pages 601-609

Human sperm chromatin epigenetic potential: Genomics, proteomics, and male infertility

Author keywords

genomics; male infertility; proteomics; sperm chromatin; sperm epigenetics

Indexed keywords

DNA; HISTONE; PROTAMINE; PROTEIN;

EID: 84973440945     PISSN: 1008682X     EISSN: 17457262     Source Type: Journal    
DOI: 10.4103/1008-682X.153302     Document Type: Conference Paper
Times cited : (67)

References (125)
  • 1
    • 0021139084 scopus 로고
    • Completion of mouse embryogenesis requires both the maternal and paternal genomes
    • McGrath J, Solter D. Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell 1984; 37: 179-83.
    • (1984) Cell , vol.37 , pp. 179-183
    • McGrath, J.1    Solter, D.2
  • 2
    • 67249153027 scopus 로고    scopus 로고
    • Epigenetics in spermatogenesis
    • Trasler JM. Epigenetics in spermatogenesis. Mol Cell Endocrinol 2009; 306: 33-6.
    • (2009) Mol Cell Endocrinol , vol.306 , pp. 33-36
    • Trasler, J.M.1
  • 3
    • 77649209897 scopus 로고    scopus 로고
    • The human sperm epigenome and its potential role in embryonic development
    • Carrell DT, Hammoud SS. The human sperm epigenome and its potential role in embryonic development. Mol Hum Reprod 2010; 16: 37-47.
    • (2010) Mol Hum Reprod , vol.16 , pp. 37-47
    • Carrell, D.T.1    Hammoud, S.S.2
  • 4
    • 84869055533 scopus 로고    scopus 로고
    • Daddy issues: Paternal effects on phenotype
    • Rando OJ. Daddy issues: paternal effects on phenotype. Cell 2012; 151: 702-8.
    • (2012) Cell , vol.151 , pp. 702-708
    • Rando, O.J.1
  • 5
    • 0035234557 scopus 로고    scopus 로고
    • Genomic imprinting: Parental influence on the genome
    • Reik W, Walter J. Genomic imprinting: parental influence on the genome. Nat Rev Genet 2001; 2: 21-32.
    • (2001) Nat Rev Genet , vol.2 , pp. 21-32
    • Reik, W.1    Walter, J.2
  • 6
    • 84867396351 scopus 로고    scopus 로고
    • Mechanisms of DNA methylation and demethylation in mammals
    • Auclair G, Weber M. Mechanisms of DNA methylation and demethylation in mammals. Biochimie 2012; 94: 2202-11.
    • (2012) Biochimie , vol.94 , pp. 2202-2211
    • Auclair, G.1    Weber, M.2
  • 8
    • 77649211158 scopus 로고    scopus 로고
    • Function of sperm chromatin structural elements in fertilization and development
    • Ward WS. Function of sperm chromatin structural elements in fertilization and development. Mol Hum Reprod 2010; 16: 30-6.
    • (2010) Mol Hum Reprod , vol.16 , pp. 30-36
    • Ward, W.S.1
  • 9
    • 75149161556 scopus 로고    scopus 로고
    • Paternal DNA packaging in spermatozoa: More than the sum of its parts? DNA, histones, protamines and epigenetics
    • Miller D, Brinkworth M, Iles D. Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigenetics. Reproduction 2010; 139: 287-301.
    • (2010) Reproduction , vol.139 , pp. 287-301
    • Miller, D.1    Brinkworth, M.2    Iles, D.3
  • 10
    • 84861514065 scopus 로고    scopus 로고
    • The sperm epigenome and potential implications for the developing embryo
    • Jenkins TG, Carrell DT. The sperm epigenome and potential implications for the developing embryo. Reproduction 2012; 143: 727-34.
    • (2012) Reproduction , vol.143 , pp. 727-734
    • Jenkins, T.G.1    Carrell, D.T.2
  • 11
    • 22944483755 scopus 로고    scopus 로고
    • Paternal contribution: New insights and future challenges
    • Krawetz SA. Paternal contribution: new insights and future challenges. Nat Rev Genet 2005; 6: 633-42.
    • (2005) Nat Rev Genet , vol.6 , pp. 633-642
    • Krawetz, S.A.1
  • 12
    • 84856401866 scopus 로고    scopus 로고
    • Epigenetics of the male gamete
    • Carrell DT. Epigenetics of the male gamete. Fertil Steril 2012; 97: 267-74.
    • (2012) Fertil Steril , vol.97 , pp. 267-274
    • Carrell, D.T.1
  • 13
    • 84987704697 scopus 로고    scopus 로고
    • Conserved properties of Drosophila and human spermatozoal mRNA repertoires
    • Fischer BE, Wasbrough E, Meadows LA, Randlet O, Dorus S, et al. Conserved properties of Drosophila and human spermatozoal mRNA repertoires. Proc Biol Sci 2012; 279: 2636-44.
    • (2012) Proc Biol Sci , vol.279 , pp. 2636-2644
    • Fischer, B.E.1    Wasbrough, E.2    Meadows, L.A.3    Randlet, O.4    Dorus, S.5
  • 14
    • 84875183056 scopus 로고    scopus 로고
    • Structure and function of long noncoding RNAs in epigenetic regulation
    • Mercer TR, Mattick JS. Structure and function of long noncoding RNAs in epigenetic regulation. Nat Struct Mol Biol 2013; 20: 300-7.
    • (2013) Nat Struct Mol Biol , vol.20 , pp. 300-307
    • Mercer, T.R.1    Mattick, J.S.2
  • 15
    • 84884829249 scopus 로고    scopus 로고
    • Mapping human epigenomes
    • Rivera CM, Ren B. Mapping human epigenomes. Cell 2013; 155: 39-55.
    • (2013) Cell , vol.155 , pp. 39-55
    • Rivera, C.M.1    Ren, B.2
  • 16
    • 12544250733 scopus 로고    scopus 로고
    • Origin and neofunctionalization of a Drosophila paternal effect gene essential for zygote viability
    • Loppin B, Lepetit D, Dorus S, Couble P, Karr TL. Origin and neofunctionalization of a Drosophila paternal effect gene essential for zygote viability. Curr Biol 2005; 15: 87-93.
    • (2005) Curr Biol , vol.15 , pp. 87-93
    • Loppin, B.1    Lepetit, D.2    Dorus, S.3    Couble, P.4    Karr, T.L.5
  • 17
    • 84899128858 scopus 로고    scopus 로고
    • Sperm nuclear proteome and its epigenetic potential
    • Castillo J, Amaral A, Oliva R. Sperm nuclear proteome and its epigenetic potential. Andrology 2014; 2: 326-38.
    • (2014) Andrology , vol.2 , pp. 326-338
    • Castillo, J.1    Amaral, A.2    Oliva, R.3
  • 18
    • 84918803645 scopus 로고    scopus 로고
    • Sperm epigenomics: Challenges and opportunities
    • Casas E, Vavouri T. Sperm epigenomics: challenges and opportunities. Front Genet 2014; 5: 330.
    • (2014) Front Genet , vol.5 , pp. 330
    • Casas, E.1    Vavouri, T.2
  • 21
    • 84934437734 scopus 로고    scopus 로고
    • Protamine alterations in human spermatozoa
    • Jodar M, Oliva R. Protamine alterations in human spermatozoa. Adv Exp Med Biol 2014; 791: 83-102.
    • (2014) Adv Exp Med Biol , vol.791 , pp. 83-102
    • Jodar, M.1    Oliva, R.2
  • 22
    • 34447650910 scopus 로고    scopus 로고
    • Sperm chromatin stability and susceptibility to damage in relation to its structure
    • De Jonge CJ, Barratt CL, editors. New York: Cambridge University Press
    • Shaman JA, Ward WS. Sperm chromatin stability and susceptibility to damage in relation to its structure. In: De Jonge CJ, Barratt CL, editors. Sperm Cell: Production, Maturation, Fertilization, Regeneration. New York: Cambridge University Press; 2006. p. 31-48.
    • (2006) Sperm Cell: Production, Maturation, Fertilization, Regeneration , pp. 31-48
    • Shaman, J.A.1    Ward, W.S.2
  • 23
    • 27944478245 scopus 로고    scopus 로고
    • DNA damage to spermatozoa has impacts on fertilization and pregnancy
    • Lewis SE, Aitken RJ. DNA damage to spermatozoa has impacts on fertilization and pregnancy. Cell Tissue Res 2005; 322: 33-41.
    • (2005) Cell Tissue Res , vol.322 , pp. 33-41
    • Lewis, S.E.1    Aitken, R.J.2
  • 24
    • 22544437838 scopus 로고    scopus 로고
    • On the nature and origin of DNA strand breaks in elongating spermatids
    • Laberge RM, Boissonneault G. On the nature and origin of DNA strand breaks in elongating spermatids. Biol Reprod 2005; 73: 289-96.
    • (2005) Biol Reprod , vol.73 , pp. 289-296
    • Laberge, R.M.1    Boissonneault, G.2
  • 25
    • 34250747441 scopus 로고    scopus 로고
    • Origins and consequences of DNA damage in male germ cells
    • Aitken RJ, De Iuliis GN. Origins and consequences of DNA damage in male germ cells. Reprod Biomed Online 2007; 14: 727-33.
    • (2007) Reprod Biomed Online , vol.14 , pp. 727-733
    • Aitken, R.J.1    De Iuliis, G.N.2
  • 26
    • 77649219526 scopus 로고    scopus 로고
    • On the possible origins of DNA damage in human spermatozoa
    • Aitken RJ, De Iuliis GN. On the possible origins of DNA damage in human spermatozoa. Mol Hum Reprod 2010; 16: 3-13.
    • (2010) Mol Hum Reprod , vol.16 , pp. 3-13
    • Aitken, R.J.1    De Iuliis, G.N.2
  • 27
    • 0026084453 scopus 로고
    • Vertebrate protamine genes and the histone-to-protamine replacement reaction
    • Oliva R, Dixon GH. Vertebrate protamine genes and the histone-to-protamine replacement reaction. Prog Nucleic Acid Res Mol Biol 1991; 40: 25-94.
    • (1991) Prog Nucleic Acid Res Mol Biol , vol.40 , pp. 25-94
    • Oliva, R.1    Dixon, G.H.2
  • 28
    • 33745255403 scopus 로고    scopus 로고
    • Protamines and male infertility
    • Oliva R. Protamines and male infertility. Hum Reprod Update 2006; 12: 417-35.
    • (2006) Hum Reprod Update , vol.12 , pp. 417-435
    • Oliva, R.1
  • 29
    • 45949103424 scopus 로고    scopus 로고
    • Proteomics in the study of the sperm cell composition, differentiation and function
    • Oliva R, Martinez-Heredia J, Estanyol JM. Proteomics in the study of the sperm cell composition, differentiation and function. Syst Biol Reprod Med 2008; 54: 23-36.
    • (2008) Syst Biol Reprod Med , vol.54 , pp. 23-36
    • Oliva, R.1    Martinez-Heredia, J.2    Estanyol, J.M.3
  • 31
    • 78650991459 scopus 로고    scopus 로고
    • Proteomics and the genetics of sperm chromatin condensation
    • Oliva R, Castillo J. Proteomics and the genetics of sperm chromatin condensation. Asian J Androl 2011; 13: 24-30.
    • (2011) Asian J Androl , vol.13 , pp. 24-30
    • Oliva, R.1    Castillo, J.2
  • 32
    • 84906100296 scopus 로고    scopus 로고
    • Parenting from before conception
    • Lane M, Robker RL, Robertson SA. Parenting from before conception. Science 2014; 345: 756-60.
    • (2014) Science , vol.345 , pp. 756-760
    • Lane, M.1    Robker, R.L.2    Robertson, S.A.3
  • 33
    • 84875204948 scopus 로고    scopus 로고
    • Dynamic alterations in the paternal epigenetic landscape following fertilization
    • Jenkins TG, Carrell DT. Dynamic alterations in the paternal epigenetic landscape following fertilization. Front Genet 2012; 3: 143.
    • (2012) Front Genet , vol.3 , pp. 143
    • Jenkins, T.G.1    Carrell, D.T.2
  • 34
    • 78650987945 scopus 로고    scopus 로고
    • Non-genetic contributions of the sperm nucleus to embryonic development
    • Yamauchi Y, Shaman JA, Ward WS. Non-genetic contributions of the sperm nucleus to embryonic development. Asian J Androl 2011; 13: 31-5.
    • (2011) Asian J Androl , vol.13 , pp. 31-35
    • Yamauchi, Y.1    Shaman, J.A.2    Ward, W.S.3
  • 35
    • 0037150676 scopus 로고    scopus 로고
    • Unique chromatin remodeling and transcriptional regulation in spermatogenesis
    • Sassone-Corsi P. Unique chromatin remodeling and transcriptional regulation in spermatogenesis. Science 2002; 296: 2176-8.
    • (2002) Science , vol.296 , pp. 2176-2178
    • Sassone-Corsi, P.1
  • 38
    • 0031843173 scopus 로고    scopus 로고
    • Histone- and protamine-DNA association: Conservation of different patterns within the beta-globin domain in human sperm
    • Gardiner-Garden M, Ballesteros M, Gordon M, Tam PP. Histone- and protamine-DNA association: conservation of different patterns within the beta-globin domain in human sperm. Mol Cell Biol 1998; 18: 3350-6.
    • (1998) Mol Cell Biol , vol.18 , pp. 3350-3356
    • Gardiner-Garden, M.1    Ballesteros, M.2    Gordon, M.3    Tam, P.P.4
  • 39
    • 0032746646 scopus 로고    scopus 로고
    • A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA
    • Pittoggi C, Renzi L, Zaccagnini G, Cimini D, Degrassi F, et al. A fraction of mouse sperm chromatin is organized in nucleosomal hypersensitive domains enriched in retroposon DNA. J Cell Sci 1999; 112 (Pt 20): 3537-48.
    • (1999) J Cell Sci , vol.112 , pp. 3537-3548
    • Pittoggi, C.1    Renzi, L.2    Zaccagnini, G.3    Cimini, D.4    Degrassi, F.5
  • 41
    • 0042031173 scopus 로고    scopus 로고
    • The structural organization of sperm chromatin
    • Wykes SM, Krawetz SA. The structural organization of sperm chromatin. J Biol Chem 2003; 278: 29471-7.
    • (2003) J Biol Chem , vol.278 , pp. 29471-29477
    • Wykes, S.M.1    Krawetz, S.A.2
  • 43
    • 68149176814 scopus 로고    scopus 로고
    • Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences
    • Arpanahi A, Brinkworth M, Iles D, Krawetz SA, Paradowska A, et al. Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences. Genome Res 2009; 19: 1338-49.
    • (2009) Genome Res , vol.19 , pp. 1338-1349
    • Arpanahi, A.1    Brinkworth, M.2    Iles, D.3    Krawetz, S.A.4    Paradowska, A.5
  • 44
    • 67749114140 scopus 로고    scopus 로고
    • Distinctive chromatin in human sperm packages genes for embryo development
    • Hammoud SS, Nix DA, Zhang H, Purwar J, Carrell DT, et al. Distinctive chromatin in human sperm packages genes for embryo development. Nature 2009; 460: 473-8.
    • (2009) Nature , vol.460 , pp. 473-478
    • Hammoud, S.S.1    Nix, D.A.2    Zhang, H.3    Purwar, J.4    Carrell, D.T.5
  • 45
    • 77953292127 scopus 로고    scopus 로고
    • Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa
    • Brykczynska U, Hisano M, Erkek S, Ramos L, Oakeley EJ, et al. Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa. Nat Struct Mol Biol 2010; 17: 679-87.
    • (2010) Nat Struct Mol Biol , vol.17 , pp. 679-687
    • Brykczynska, U.1    Hisano, M.2    Erkek, S.3    Ramos, L.4    Oakeley, E.J.5
  • 46
    • 79960449192 scopus 로고    scopus 로고
    • Key gene regulatory sequences with distinctive ontological signatures associate with differentially endonuclease-accessible mouse sperm chromatin
    • Saida M, Iles D, Elnefati A, Brinkworth M, Miller D. Key gene regulatory sequences with distinctive ontological signatures associate with differentially endonuclease-accessible mouse sperm chromatin. Reproduction 2011; 142: 73-86.
    • (2011) Reproduction , vol.142 , pp. 73-86
    • Saida, M.1    Iles, D.2    Elnefati, A.3    Brinkworth, M.4    Miller, D.5
  • 47
    • 79955610452 scopus 로고    scopus 로고
    • Chromatin organization in sperm may be the major functional consequence of base composition variation in the human genome
    • Vavouri T, Lehner B. Chromatin organization in sperm may be the major functional consequence of base composition variation in the human genome. PLoS Genet 2011; 7: e1002036.
    • (2011) PLoS Genet , vol.7 , pp. e1002036
    • Vavouri, T.1    Lehner, B.2
  • 48
    • 84880179559 scopus 로고    scopus 로고
    • Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa
    • Erkek S, Hisano M, Liang CY, Gill M, Murr R, et al. Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa. Nat Struct Mol Biol 2013; 20: 868-75.
    • (2013) Nat Struct Mol Biol , vol.20 , pp. 868-875
    • Erkek, S.1    Hisano, M.2    Liang, C.Y.3    Gill, M.4    Murr, R.5
  • 49
    • 84880795001 scopus 로고    scopus 로고
    • Alteration of poly (ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation
    • Meyer-Ficca ML, Lonchar JD, Ihara M, Bader JJ, Meyer RG. Alteration of poly (ADP-ribose) metabolism affects murine sperm nuclear architecture by impairing pericentric heterochromatin condensation. Chromosoma 2013; 122: 319-35.
    • (2013) Chromosoma , vol.122 , pp. 319-335
    • Meyer-Ficca, M.L.1    Lonchar, J.D.2    Ihara, M.3    Bader, J.J.4    Meyer, R.G.5
  • 50
    • 84904261107 scopus 로고    scopus 로고
    • High-resolution mapping of chromatin packaging in mouse embryonic stem cells and sperm
    • Carone BR, Hung JH, Hainer SJ, Chou MT, Carone DM, et al. High-resolution mapping of chromatin packaging in mouse embryonic stem cells and sperm. Dev Cell 2014; 30: 11-22.
    • (2014) Dev Cell , vol.30 , pp. 11-22
    • Carone, B.R.1    Hung, J.H.2    Hainer, S.J.3    Chou, M.T.4    Carone, D.M.5
  • 51
    • 84913586576 scopus 로고    scopus 로고
    • Genomic and proteomic dissection and characterization of the human sperm chromatin
    • Castillo J, Amaral A, Azpiazu R, Vavouri T, Estanyol JM, et al. Genomic and proteomic dissection and characterization of the human sperm chromatin. Mol Hum Reprod 2014; 20: 1041-53.
    • (2014) Mol Hum Reprod , vol.20 , pp. 1041-1053
    • Castillo, J.1    Amaral, A.2    Azpiazu, R.3    Vavouri, T.4    Estanyol, J.M.5
  • 52
    • 84904261663 scopus 로고    scopus 로고
    • Uniformity of nucleosome preservation pattern in Mammalian sperm and its connection to repetitive DNA elements
    • Samans B, Yang Y, Krebs S, Sarode GV, Blum H, et al. Uniformity of nucleosome preservation pattern in Mammalian sperm and its connection to repetitive DNA elements. Dev Cell 2014; 30: 23-35.
    • (2014) Dev Cell , vol.30 , pp. 23-35
    • Samans, B.1    Yang, Y.2    Krebs, S.3    Sarode, G.V.4    Blum, H.5
  • 53
    • 0025201535 scopus 로고
    • Isolation of four core histones from human sperm chromatin representing a minor subset of somatic histones
    • Gatewood JM, Cook GR, Balhorn R, Schmid CW, Bradbury EM. Isolation of four core histones from human sperm chromatin representing a minor subset of somatic histones. J Biol Chem 1990; 265: 20662-6.
    • (1990) J Biol Chem , vol.265 , pp. 20662-20666
    • Gatewood, J.M.1    Cook, G.R.2    Balhorn, R.3    Schmid, C.W.4    Bradbury, E.M.5
  • 54
    • 84858035113 scopus 로고    scopus 로고
    • Altered histone retention and epigenetic modifications in the sperm of infertile men
    • Oliva R, Ballescà JL. Altered histone retention and epigenetic modifications in the sperm of infertile men. Asian J Androl 2012; 14: 239-40.
    • (2012) Asian J Androl , vol.14 , pp. 239-240
    • Oliva, R.1    Ballescà, J.L.2
  • 55
    • 79953321016 scopus 로고    scopus 로고
    • Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm
    • Wu SF, Zhang H, Cairns BR. Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm. Genome Res 2011; 21: 578-89.
    • (2011) Genome Res , vol.21 , pp. 578-589
    • Wu, S.F.1    Zhang, H.2    Cairns, B.R.3
  • 57
    • 44049104999 scopus 로고    scopus 로고
    • The protamine family of sperm nuclear proteins
    • Balhorn R. The protamine family of sperm nuclear proteins. Genome Biol 2007; 8: 227.
    • (2007) Genome Biol , vol.8 , pp. 227
    • Balhorn, R.1
  • 59
    • 34447122772 scopus 로고    scopus 로고
    • The sperm nuclear matrix is required for paternal DNA replication
    • Shaman JA, Yamauchi Y, Ward WS. The sperm nuclear matrix is required for paternal DNA replication. J Cell Biochem 2007; 102: 680-8.
    • (2007) J Cell Biochem , vol.102 , pp. 680-688
    • Shaman, J.A.1    Yamauchi, Y.2    Ward, W.S.3
  • 60
    • 0036015206 scopus 로고    scopus 로고
    • Sperm nuclear halos can transform into normal chromosomes after injection into oocytes
    • Mohar I, Szczygiel MA, Yanagimachi R, Ward WS. Sperm nuclear halos can transform into normal chromosomes after injection into oocytes. Mol Reprod Dev 2002; 62: 416-20.
    • (2002) Mol Reprod Dev , vol.62 , pp. 416-420
    • Mohar, I.1    Szczygiel, M.A.2    Yanagimachi, R.3    Ward, W.S.4
  • 61
    • 79960926862 scopus 로고    scopus 로고
    • Protamine/DNA ratios and DNA damage in native and density gradient centrifuged sperm from infertile patients
    • Castillo J, Simon L, de Mateo S, Lewis S, Oliva R. Protamine/DNA ratios and DNA damage in native and density gradient centrifuged sperm from infertile patients. J Androl 2011; 32: 324-32.
    • (2011) J Androl , vol.32 , pp. 324-332
    • Castillo, J.1    Simon, L.2    De Mateo, S.3    Lewis, S.4    Oliva, R.5
  • 62
    • 82855172054 scopus 로고    scopus 로고
    • Relationships between human sperm protamines, DNA damage and assisted reproduction outcomes
    • Simon L, Castillo J, Oliva R, Lewis SE. Relationships between human sperm protamines, DNA damage and assisted reproduction outcomes. Reprod Biomed Online 2011; 23: 724-34.
    • (2011) Reprod Biomed Online , vol.23 , pp. 724-734
    • Simon, L.1    Castillo, J.2    Oliva, R.3    Lewis, S.E.4
  • 63
  • 64
    • 26944466235 scopus 로고    scopus 로고
    • DNA integrity is compromised in protamine-deficient human sperm
    • Aoki VW, Moskovtsev SI, Willis J, Liu L, Mullen JB, et al. DNA integrity is compromised in protamine-deficient human sperm. J Androl 2005; 26: 741-8.
    • (2005) J Androl , vol.26 , pp. 741-748
    • Aoki, V.W.1    Moskovtsev, S.I.2    Willis, J.3    Liu, L.4    Mullen, J.B.5
  • 65
    • 33745258535 scopus 로고    scopus 로고
    • Protamine 2 precursors, protamine 1/protamine 2 ratio, DNA integrity and other sperm parameters in infertile patients
    • Torregrosa N, Dominguez-Fandos D, Camejo MI, Shirley CR, Meistrich ML, et al. Protamine 2 precursors, protamine 1/protamine 2 ratio, DNA integrity and other sperm parameters in infertile patients. Hum Reprod 2006; 21: 2084-9.
    • (2006) Hum Reprod , vol.21 , pp. 2084-2089
    • Torregrosa, N.1    Dominguez-Fandos, D.2    Camejo, M.I.3    Shirley, C.R.4    Meistrich, M.L.5
  • 66
    • 78650172833 scopus 로고    scopus 로고
    • Specialization of a Drosophila capping protein essential for the protection of sperm telomeres
    • Dubruille R, Orsi GA, Delabaere L, Cortier E, Couble P, et al. Specialization of a Drosophila capping protein essential for the protection of sperm telomeres. Curr Biol 2010; 20: 2090-9.
    • (2010) Curr Biol , vol.20 , pp. 2090-2099
    • Dubruille, R.1    Orsi, G.A.2    Delabaere, L.3    Cortier, E.4    Couble, P.5
  • 69
    • 4544376137 scopus 로고    scopus 로고
    • The role of histones in chromatin remodelling during mammalian spermiogenesis
    • Govin J, Caron C, Lestrat C, Rousseaux S, Khochbin S. The role of histones in chromatin remodelling during mammalian spermiogenesis. Eur J Biochem 2004; 271: 3459-69.
    • (2004) Eur J Biochem , vol.271 , pp. 3459-3469
    • Govin, J.1    Caron, C.2    Lestrat, C.3    Rousseaux, S.4    Khochbin, S.5
  • 70
    • 33846567551 scopus 로고    scopus 로고
    • Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis
    • Govin J, Escoffier E, Rousseaux S, Kuhn L, Ferro M, et al. Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis. J Cell Biol 2007; 176: 283-94.
    • (2007) J Cell Biol , vol.176 , pp. 283-294
    • Govin, J.1    Escoffier, E.2    Rousseaux, S.3    Kuhn, L.4    Ferro, M.5
  • 71
    • 84881062290 scopus 로고    scopus 로고
    • Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B
    • Montellier E, Boussouar F, Rousseaux S, Zhang K, Buchou T, et al. Chromatin-to-nucleoprotamine transition is controlled by the histone H2B variant TH2B. Genes Dev 2013; 27: 1680-92.
    • (2013) Genes Dev , vol.27 , pp. 1680-1692
    • Montellier, E.1    Boussouar, F.2    Rousseaux, S.3    Zhang, K.4    Buchou, T.5
  • 72
    • 77951222534 scopus 로고    scopus 로고
    • H2A.Bbd: An X-chromosome-encoded histone involved in mammalian spermiogenesis
    • Ishibashi T, Li A, Eirin-Lopez JM, Zhao M, Missiaen K, et al. H2A.Bbd: an X-chromosome-encoded histone involved in mammalian spermiogenesis. Nucleic Acids Res 2010; 38: 1780-9.
    • (2010) Nucleic Acids Res , vol.38 , pp. 1780-1789
    • Ishibashi, T.1    Li, A.2    Eirin-Lopez, J.M.3    Zhao, M.4    Missiaen, K.5
  • 73
    • 84892464356 scopus 로고    scopus 로고
    • Epigenetic marking of sperm by post-translational modification of histones and protamines
    • Brunner AM, Nanni P, Mansuy IM. Epigenetic marking of sperm by post-translational modification of histones and protamines. Epigenetics Chromatin 2014; 7: 2.
    • (2014) Epigenetics Chromatin , vol.7 , pp. 2
    • Brunner, A.M.1    Nanni, P.2    Mansuy, I.M.3
  • 74
    • 84908315044 scopus 로고    scopus 로고
    • The specification and global reprogramming of histone epigenetic marks during gamete formation and early embryo development in C. Elegans
    • Samson M, Jow MM, Wong CC, Fitzpatrick C, Aslanian A, et al. The specification and global reprogramming of histone epigenetic marks during gamete formation and early embryo development in C. elegans. PLoS Genet 2014; 10: e1004588.
    • (2014) PLoS Genet , vol.10 , pp. e1004588
    • Samson, M.1    Jow, M.M.2    Wong, C.C.3    Fitzpatrick, C.4    Aslanian, A.5
  • 75
    • 0020488059 scopus 로고
    • Histone H4 hyperacetylation and rapid turnover of its acetyl groups in transcriptionally inactive rooster testis spermatids
    • Oliva R, Mezquita C. Histone H4 hyperacetylation and rapid turnover of its acetyl groups in transcriptionally inactive rooster testis spermatids. Nucleic Acids Res 1982; 10: 8049-59.
    • (1982) Nucleic Acids Res , vol.10 , pp. 8049-8059
    • Oliva, R.1    Mezquita, C.2
  • 76
    • 0023657268 scopus 로고
    • Factors affecting nucleosome disassembly by protamines in vitro. Histone hyperacetylation and chromatin structure, time dependence, and the size of the sperm nuclear proteins
    • Oliva R, Bazett-Jones D, Mezquita C, Dixon GH. Factors affecting nucleosome disassembly by protamines in vitro. Histone hyperacetylation and chromatin structure, time dependence, and the size of the sperm nuclear proteins. J Biol Chem 1987; 262: 17016-25.
    • (1987) J Biol Chem , vol.262 , pp. 17016-17025
    • Oliva, R.1    Bazett-Jones, D.2    Mezquita, C.3    Dixon, G.H.4
  • 77
    • 0025321665 scopus 로고
    • Histone hyperacetylation can induce unfolding of the nucleosome core particle
    • Oliva R, Bazett-Jones DP, Locklear L, Dixon GH. Histone hyperacetylation can induce unfolding of the nucleosome core particle. Nucleic Acids Res 1990; 18: 2739-47.
    • (1990) Nucleic Acids Res , vol.18 , pp. 2739-2747
    • Oliva, R.1    Bazett-Jones, D.P.2    Locklear, L.3    Dixon, G.H.4
  • 78
    • 36849080253 scopus 로고    scopus 로고
    • Acetylation of histone H4 in complex structural transitions of spermiogenic chromatin
    • Kurtz K, Martinez-Soler F, Ausió J, Chiva M. Acetylation of histone H4 in complex structural transitions of spermiogenic chromatin. J Cell Biochem 2007; 102: 1432-41.
    • (2007) J Cell Biochem , vol.102 , pp. 1432-1441
    • Kurtz, K.1    Martinez-Soler, F.2    Ausió, J.3    Chiva, M.4
  • 79
    • 77249162176 scopus 로고    scopus 로고
    • Histone H4 acetylation is essential to proceed from a histone- to a protamine-based chromatin structure in spermatid nuclei of Drosophila melanogaster
    • Awe S, Renkawitz-Pohl R. Histone H4 acetylation is essential to proceed from a histone- to a protamine-based chromatin structure in spermatid nuclei of Drosophila melanogaster. Syst Biol Reprod Med 2010; 56: 44-61.
    • (2010) Syst Biol Reprod Med , vol.56 , pp. 44-61
    • Awe, S.1    Renkawitz-Pohl, R.2
  • 80
    • 84907583499 scopus 로고    scopus 로고
    • Genome-scale acetylation-dependent histone eviction during spermatogenesis
    • Goudarzi A, Shiota H, Rousseaux S, Khochbin S. Genome-scale acetylation-dependent histone eviction during spermatogenesis. J Mol Biol 2014; 426: 3342-9.
    • (2014) J Mol Biol , vol.426 , pp. 3342-3349
    • Goudarzi, A.1    Shiota, H.2    Rousseaux, S.3    Khochbin, S.4
  • 81
    • 33748986324 scopus 로고    scopus 로고
    • Transmission of modified nucleosomes from the mouse male germline to the zygote and subsequent remodeling of paternal chromatin
    • van der Heijden GW, Derijck AA, Ramos L, Giele M, van der Vlag J, et al. Transmission of modified nucleosomes from the mouse male germline to the zygote and subsequent remodeling of paternal chromatin. Dev Biol 2006; 298: 458-69.
    • (2006) Dev Biol , vol.298 , pp. 458-469
    • Van Der-Heijden, G.W.1    Derijck, A.A.2    Ramos, L.3    Giele, M.4    Van Der-Vlag, J.5
  • 82
    • 84857046239 scopus 로고    scopus 로고
    • Histone crotonylation specifically marks the haploid male germ cell gene expression program: Post-meiotic male-specific gene expression
    • Montellier E, Rousseaux S, Zhao Y, Khochbin S. Histone crotonylation specifically marks the haploid male germ cell gene expression program: post-meiotic male-specific gene expression. Bioessays 2012; 34: 187-93.
    • (2012) Bioessays , vol.34 , pp. 187-193
    • Montellier, E.1    Rousseaux, S.2    Zhao, Y.3    Khochbin, S.4
  • 83
    • 0023280058 scopus 로고
    • Phosphorylation state of protamines 1 and 2 in human spermatids and spermatozoa
    • Pruslin FH, Imesch E, Winston R, Rodman TC. Phosphorylation state of protamines 1 and 2 in human spermatids and spermatozoa. Gamete Res 1987; 18: 179-90.
    • (1987) Gamete Res , vol.18 , pp. 179-190
    • Pruslin, F.H.1    Imesch, E.2    Winston, R.3    Rodman, T.C.4
  • 84
    • 0027364429 scopus 로고
    • Phosphorylation of human sperm protamines HP1 and HP2: Identification of phosphorylation sites
    • Chirat F, Arkhis A, Martinage A, Jaquinod M, Chevaillier P, et al. Phosphorylation of human sperm protamines HP1 and HP2: identification of phosphorylation sites. Biochim Biophys Acta 1993; 1203: 109-14.
    • (1993) Biochim Biophys Acta , vol.1203 , pp. 109-114
    • Chirat, F.1    Arkhis, A.2    Martinage, A.3    Jaquinod, M.4    Chevaillier, P.5
  • 85
    • 0028280420 scopus 로고
    • Identification of phosphoseryl residues in protamines from mature mammalian spermatozoa
    • Pirhonen A, Linnala-Kankkunen A, Mäenpää PH. Identification of phosphoseryl residues in protamines from mature mammalian spermatozoa. Biol Reprod 1994; 50: 981-6.
    • (1994) Biol Reprod , vol.50 , pp. 981-986
    • Pirhonen, A.1    Linnala-Kankkunen, A.2    Mäenpää, P.H.3
  • 86
    • 0018411008 scopus 로고
    • The formation of disulfide bonds in human protamines during sperm maturation
    • Saowaros W, Panyim S. The formation of disulfide bonds in human protamines during sperm maturation. Experientia 1979; 35: 191-2.
    • (1979) Experientia , vol.35 , pp. 191-192
    • Saowaros, W.1    Panyim, S.2
  • 87
    • 84934444885 scopus 로고    scopus 로고
    • Structure of chromatin in spermatozoa
    • Björndahl L, Kvist U. Structure of chromatin in spermatozoa. Adv Exp Med Biol 2014; 791: 1-11.
    • (2014) Adv Exp Med Biol , vol.791 , pp. 1-11
    • Björndahl, L.1    Kvist, U.2
  • 88
    • 0017580166 scopus 로고
    • Studies on sex-organ development. Changes in nuclear and chromatin composition and genomic activity during spermatogenesis in the maturing rooster testis
    • Mezquita C, Teng CS. Studies on sex-organ development. Changes in nuclear and chromatin composition and genomic activity during spermatogenesis in the maturing rooster testis. Biochem J 1977; 164: 99-111.
    • (1977) Biochem J , vol.164 , pp. 99-111
    • Mezquita, C.1    Teng, C.S.2
  • 89
    • 0015869217 scopus 로고
    • Protamines. Isolation, characterization, structure and function
    • Ando T, Yamasaki M, Suzuki K. Protamines. Isolation, characterization, structure and function. Mol Biol Biochem Biophys 1973; 12: 1-114.
    • (1973) Mol Biol Biochem Biophys , vol.12 , pp. 1-114
    • Ando, T.1    Yamasaki, M.2    Suzuki, K.3
  • 90
    • 55449099360 scopus 로고    scopus 로고
    • The aetiology of sperm protamine abnormalities and their potential impact on the sperm epigenome
    • Carrell DT, Emery BR, Hammoud S. The aetiology of sperm protamine abnormalities and their potential impact on the sperm epigenome. Int J Androl 2008; 31: 537-45.
    • (2008) Int J Androl , vol.31 , pp. 537-545
    • Carrell, D.T.1    Emery, B.R.2    Hammoud, S.3
  • 91
    • 0023030892 scopus 로고
    • Marked differences in the ability of distinct protamines to disassemble nucleosomal core particles in vitro
    • Oliva R, Mezquita C. Marked differences in the ability of distinct protamines to disassemble nucleosomal core particles in vitro. Biochemistry 1986; 25: 6508-11.
    • (1986) Biochemistry , vol.25 , pp. 6508-6511
    • Oliva, R.1    Mezquita, C.2
  • 92
    • 0346648550 scopus 로고    scopus 로고
    • Marked differences in protamine content and P1/P2 ratios in sperm cells from percoll fractions between patients and controls
    • Mengual L, Ballescá JL, Ascaso C, Oliva R. Marked differences in protamine content and P1/P2 ratios in sperm cells from percoll fractions between patients and controls. J Androl 2003; 24: 438-47.
    • (2003) J Androl , vol.24 , pp. 438-447
    • Mengual, L.1    Ballescá, J.L.2    Ascaso, C.3    Oliva, R.4
  • 93
    • 84896784289 scopus 로고    scopus 로고
    • The top-down, middle-down, and bottom-up mass spectrometry approaches for characterization of histone variants and their post-translational modifications
    • Moradian A, Kalli A, Sweredoski MJ, Hess S. The top-down, middle-down, and bottom-up mass spectrometry approaches for characterization of histone variants and their post-translational modifications. Proteomics 2014; 14: 489-97.
    • (2014) Proteomics , vol.14 , pp. 489-497
    • Moradian, A.1    Kalli, A.2    Sweredoski, M.J.3    Hess, S.4
  • 94
    • 0027340148 scopus 로고
    • Rapid analysis of mammalian sperm nuclear proteins
    • de Yebra L, Oliva R. Rapid analysis of mammalian sperm nuclear proteins. Anal Biochem 1993; 209: 201-3.
    • (1993) Anal Biochem , vol.209 , pp. 201-203
    • De Yebra, L.1    Oliva, R.2
  • 95
    • 61449164141 scopus 로고    scopus 로고
    • Protamine 2 precursors (Pre-P2), protamine 1 to protamine 2 ratio (P1/P2), and assisted reproduction outcome
    • de Mateo S, Gázquez C, Guimerà M, Balasch J, Meistrich ML, et al. Protamine 2 precursors (Pre-P2), protamine 1 to protamine 2 ratio (P1/P2), and assisted reproduction outcome. Fertil Steril 2009; 91: 715-22.
    • (2009) Fertil Steril , vol.91 , pp. 715-722
    • De Mateo, S.1    Gázquez, C.2    Guimerà, M.3    Balasch, J.4    Meistrich, M.L.5
  • 96
    • 79955589981 scopus 로고    scopus 로고
    • Improvement in chromatin maturity of human spermatozoa selected through density gradient centrifugation
    • de Mateo S, Ramos L, van der Vlag J, de Boer P, Oliva R. Improvement in chromatin maturity of human spermatozoa selected through density gradient centrifugation. Int J Androl 2011; 34: 256-67.
    • (2011) Int J Androl , vol.34 , pp. 256-267
    • De Mateo, S.1    Ramos, L.2    Van Der-Vlag, J.3    De Boer, P.4    Oliva, R.5
  • 98
    • 84931366631 scopus 로고    scopus 로고
    • The effect of tetrabromobisphenol A on protamine content and DNA integrity in mouse spermatozoa
    • Zatecka E, Castillo J, Elzeinova F, Kubatova A, Ded L, et al. The effect of tetrabromobisphenol A on protamine content and DNA integrity in mouse spermatozoa. Andrology 2014; 2: 910-7.
    • (2014) Andrology , vol.2 , pp. 910-917
    • Zatecka, E.1    Castillo, J.2    Elzeinova, F.3    Kubatova, A.4    Ded, L.5
  • 99
    • 0031977267 scopus 로고    scopus 로고
    • Detection of P2 precursors in the sperm cells of infertile patients who have reduced protamine P2 levels
    • de Yebra L, Ballescá JL, Vanrell JA, Corzett M, Balhorn R, et al. Detection of P2 precursors in the sperm cells of infertile patients who have reduced protamine P2 levels. Fertil Steril 1998; 69: 755-9.
    • (1998) Fertil Steril , vol.69 , pp. 755-759
    • De Yebra, L.1    Ballescá, J.L.2    Vanrell, J.A.3    Corzett, M.4    Balhorn, R.5
  • 100
    • 0031807090 scopus 로고    scopus 로고
    • Protein and DNA contents in sperm from an infertile human male possessing protamine defects that vary over time
    • Bench G, Corzett MH, De Yebra L, Oliva R, Balhorn R. Protein and DNA contents in sperm from an infertile human male possessing protamine defects that vary over time. Mol Reprod Dev 1998; 50: 345-53.
    • (1998) Mol Reprod Dev , vol.50 , pp. 345-353
    • Bench, G.1    Corzett, M.H.2    De Yebra, L.3    Oliva, R.4    Balhorn, R.5
  • 101
    • 84872388084 scopus 로고    scopus 로고
    • Head and flagella subcompartmental proteomic analysis of human spermatozoa
    • Baker MA, Naumovski N, Hetherington L, Weinberg A, Velkov T, et al. Head and flagella subcompartmental proteomic analysis of human spermatozoa. Proteomics 2013; 13: 61-74.
    • (2013) Proteomics , vol.13 , pp. 61-74
    • Baker, M.A.1    Naumovski, N.2    Hetherington, L.3    Weinberg, A.4    Velkov, T.5
  • 102
    • 33751510977 scopus 로고    scopus 로고
    • Genomic and functional evolution of the Drosophila melanogaster sperm proteome
    • Dorus S, Busby SA, Gerike U, Shabanowitz J, Hunt DF, et al. Genomic and functional evolution of the Drosophila melanogaster sperm proteome. Nat Genet 2006; 38: 1440-5.
    • (2006) Nat Genet , vol.38 , pp. 1440-1445
    • Dorus, S.1    Busby, S.A.2    Gerike, U.3    Shabanowitz, J.4    Hunt, D.F.5
  • 103
    • 37049034594 scopus 로고    scopus 로고
    • Identification of gene products present in Triton X-100 soluble and insoluble fractions of human spermatozoa lysates using LC-MS/MS analysis
    • Baker MA, Reeves G, Hetherington L, Müller J, Baur I, et al. Identification of gene products present in Triton X-100 soluble and insoluble fractions of human spermatozoa lysates using LC-MS/MS analysis. Proteomics Clin Appl 2007; 1: 524-32.
    • (2007) Proteomics Clin Appl , vol.1 , pp. 524-532
    • Baker, M.A.1    Reeves, G.2    Hetherington, L.3    Müller, J.4    Baur, I.5
  • 105
    • 84934443766 scopus 로고    scopus 로고
    • Methods for the analysis of the sperm proteome
    • de Mateo S, Estanyol JM, Oliva R. Methods for the analysis of the sperm proteome. Methods Mol Biol 2013; 927: 411-22.
    • (2013) Methods Mol Biol , vol.927 , pp. 411-422
    • De Mateo, S.1    Estanyol, J.M.2    Oliva, R.3
  • 106
    • 84872418742 scopus 로고    scopus 로고
    • In-depth proteomic analysis of the human sperm reveals complex protein compositions
    • Wang G, Guo Y, Zhou T, Shi X, Yu J, et al. In-depth proteomic analysis of the human sperm reveals complex protein compositions. J Proteomics 2013; 79: 114-22.
    • (2013) J Proteomics , vol.79 , pp. 114-122
    • Wang, G.1    Guo, Y.2    Zhou, T.3    Shi, X.4    Yu, J.5
  • 107
    • 84889633604 scopus 로고    scopus 로고
    • The combined human sperm proteome: Cellular pathways and implications for basic and clinical science
    • Amaral A, Castillo J, Ramalho-Santos J, Oliva R. The combined human sperm proteome: cellular pathways and implications for basic and clinical science. Hum Reprod Update 2014; 20: 40-62.
    • (2014) Hum Reprod Update , vol.20 , pp. 40-62
    • Amaral, A.1    Castillo, J.2    Ramalho-Santos, J.3    Oliva, R.4
  • 109
    • 0042090936 scopus 로고    scopus 로고
    • Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein
    • Pivot-Pajot C, Caron C, Govin J, Vion A, Rousseaux S, et al. Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein. Mol Cell Biol 2003; 23: 5354-65.
    • (2003) Mol Cell Biol , vol.23 , pp. 5354-5365
    • Pivot-Pajot, C.1    Caron, C.2    Govin, J.3    Vion, A.4    Rousseaux, S.5
  • 110
    • 77956202078 scopus 로고    scopus 로고
    • The interaction of modified histones with the bromodomain testis-specific (BRDT) gene and its mRNA level in sperm of fertile donors and subfertile men
    • Steilmann C, Cavalcanti MC, Bartkuhn M, Pons-Kuhnemann J, Schuppe HC, et al. The interaction of modified histones with the bromodomain testis-specific (BRDT) gene and its mRNA level in sperm of fertile donors and subfertile men. Reproduction 2010; 140: 435-43.
    • (2010) Reproduction , vol.140 , pp. 435-443
    • Steilmann, C.1    Cavalcanti, M.C.2    Bartkuhn, M.3    Pons-Kuhnemann, J.4    Schuppe, H.C.5
  • 111
    • 82255183199 scopus 로고    scopus 로고
    • Handpicking epigenetic marks with PHD fingers
    • Musselman CA, Kutateladze TG. Handpicking epigenetic marks with PHD fingers. Nucleic Acids Res 2011; 39: 9061-71.
    • (2011) Nucleic Acids Res , vol.39 , pp. 9061-9071
    • Musselman, C.A.1    Kutateladze, T.G.2
  • 112
    • 14344256084 scopus 로고    scopus 로고
    • An endogenous nuclease in hamster, mouse, and human spermatozoa cleaves DNA into loop-sized fragments
    • Sotolongo B, Huang TT, Isenberger E, Ward WS. An endogenous nuclease in hamster, mouse, and human spermatozoa cleaves DNA into loop-sized fragments. J Androl 2005; 26: 272-80.
    • (2005) J Androl , vol.26 , pp. 272-280
    • Sotolongo, B.1    Huang, T.T.2    Isenberger, E.3    Ward, W.S.4
  • 113
    • 0024437995 scopus 로고
    • DNA topoisomerase II activity in nonreplicating, transcriptionally inactive, chicken late spermatids
    • Roca J, Mezquita C. DNA topoisomerase II activity in nonreplicating, transcriptionally inactive, chicken late spermatids. EMBO J 1989; 8: 1855-60.
    • (1989) EMBO J , vol.8 , pp. 1855-1860
    • Roca, J.1    Mezquita, C.2
  • 114
    • 84896443644 scopus 로고    scopus 로고
    • Double-stranded DNA breaks hidden in the neutral Comet assay suggest a role of the sperm nuclear matrix in DNA integrity maintenance
    • Ribas-Maynou J, Gawecka JE, Benet J, Ward WS. Double-stranded DNA breaks hidden in the neutral Comet assay suggest a role of the sperm nuclear matrix in DNA integrity maintenance. Mol Hum Reprod 2014; 20: 330-40.
    • (2014) Mol Hum Reprod , vol.20 , pp. 330-340
    • Ribas-Maynou, J.1    Gawecka, J.E.2    Benet, J.3    Ward, W.S.4
  • 115
    • 77957194585 scopus 로고    scopus 로고
    • Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility
    • Hammoud SS, Purwar J, Pflueger C, Cairns BR, Carrell DT. Alterations in sperm DNA methylation patterns at imprinted loci in two classes of infertility. Fertil Steril 2010; 94: 1728-33.
    • (2010) Fertil Steril , vol.94 , pp. 1728-1733
    • Hammoud, S.S.1    Purwar, J.2    Pflueger, C.3    Cairns, B.R.4    Carrell, D.T.5
  • 116
    • 77954416527 scopus 로고    scopus 로고
    • Idiopathic male infertility is strongly associated with aberrant methylation of MEST and IGF2/H19 ICR1
    • Poplinski A, Tüttelmann F, Kanber D, Horsthemke B, Gromoll J. Idiopathic male infertility is strongly associated with aberrant methylation of MEST and IGF2/H19 ICR1. Int J Androl 2010; 33: 642-9.
    • (2010) Int J Androl , vol.33 , pp. 642-649
    • Poplinski, A.1    Tüttelmann, F.2    Kanber, D.3    Horsthemke, B.4    Gromoll, J.5
  • 117
    • 79957968811 scopus 로고    scopus 로고
    • Integrative DNA methylation and gene expression analyses identify DNA packaging and epigenetic regulatory genes associated with low motility sperm
    • Pacheco SE, Houseman EA, Christensen BC, Marsit CJ, Kelsey KT, et al. Integrative DNA methylation and gene expression analyses identify DNA packaging and epigenetic regulatory genes associated with low motility sperm. PLoS One 2011; 6: e20280.
    • (2011) PLoS One , vol.6 , pp. e20280
    • Pacheco, S.E.1    Houseman, E.A.2    Christensen, B.C.3    Marsit, C.J.4    Kelsey, K.T.5
  • 118
    • 84862908733 scopus 로고    scopus 로고
    • Sperm-borne microRNA-34c is required for the first cleavage division in mouse
    • Liu WM, Pang RT, Chiu PC, Wong BP, Lao K, et al. Sperm-borne microRNA-34c is required for the first cleavage division in mouse. Proc Natl Acad Sci U S A 2012; 109: 490-4.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 490-494
    • Liu, W.M.1    Pang, R.T.2    Chiu, P.C.3    Wong, B.P.4    Lao, K.5
  • 119
    • 80051949165 scopus 로고    scopus 로고
    • Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men
    • Hammoud SS, Nix DA, Hammoud AO, Gibson M, Cairns BR, et al. Genome-wide analysis identifies changes in histone retention and epigenetic modifications at developmental and imprinted gene loci in the sperm of infertile men. Hum Reprod 2011; 26: 2558-69.
    • (2011) Hum Reprod , vol.26 , pp. 2558-2569
    • Hammoud, S.S.1    Nix, D.A.2    Hammoud, A.O.3    Gibson, M.4    Cairns, B.R.5
  • 120
    • 84900793731 scopus 로고    scopus 로고
    • High-throughput sperm differential proteomics suggests that epigenetic alterations contribute to failed assisted reproduction
    • Azpiazu R, Amaral A, Castillo J, Estanyol JM, Guimerà M, et al. High-throughput sperm differential proteomics suggests that epigenetic alterations contribute to failed assisted reproduction. Hum Reprod 2014; 29: 1225-37.
    • (2014) Hum Reprod , vol.29 , pp. 1225-1237
    • Azpiazu, R.1    Amaral, A.2    Castillo, J.3    Estanyol, J.M.4    Guimerà, M.5
  • 121
    • 0023839404 scopus 로고
    • Aberrant protamine 1/protamine 2 ratios in sperm of infertile human males
    • Balhorn R, Reed S, Tanphaichitr N. Aberrant protamine 1/protamine 2 ratios in sperm of infertile human males. Experientia 1988; 44: 52-5.
    • (1988) Experientia , vol.44 , pp. 52-55
    • Balhorn, R.1    Reed, S.2    Tanphaichitr, N.3
  • 122
    • 84901642367 scopus 로고    scopus 로고
    • Paternal poly (ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression
    • Ihara M, Meyer-Ficca ML, Leu NA, Rao S, Li F, et al. Paternal poly (ADP-ribose) metabolism modulates retention of inheritable sperm histones and early embryonic gene expression. PLoS Genet 2014; 10: e1004317.
    • (2014) PLoS Genet , vol.10 , pp. e1004317
    • Ihara, M.1    Meyer-Ficca, M.L.2    Leu, N.A.3    Rao, S.4    Li, F.5
  • 123
    • 84876410606 scopus 로고    scopus 로고
    • The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility
    • Kovac JR, Pastuszak AW, Lamb DJ. The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility. Fertil Steril 2013; 99: 998-1007.
    • (2013) Fertil Steril , vol.99 , pp. 998-1007
    • Kovac, J.R.1    Pastuszak, A.W.2    Lamb, D.J.3
  • 124
    • 0027317135 scopus 로고
    • Identification of the elemental packing unit of DNA in mammalian sperm cells by atomic force microscopy
    • Hud NV, Allen MJ, Downing KH, Lee J, Balhorn R. Identification of the elemental packing unit of DNA in mammalian sperm cells by atomic force microscopy. Biochem Biophys Res Commun 1993; 193: 1347-54.
    • (1993) Biochem Biophys Res Commun , vol.193 , pp. 1347-1354
    • Hud, N.V.1    Allen, M.J.2    Downing, K.H.3    Lee, J.4    Balhorn, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.