Fe2+ binding on amyloid β-peptide promotes aggregation

Proteins: Structure, Function and Bioinformatics

Volumn 84, Issue 9, 2016, Pages 1257-1274

  Boopathi, Subramaniam ^a   Kolandaivel, Ponmalai ^a  

^a BHARATHIAR UNIVERSITY   (India)

Author keywords

Alzheimer's diseases; amyloid peptide; metal ions; molecular dynamics simulation; U shaped conformation

Indexed keywords

AMYLOID BETA PROTEIN; COPPER ION; FERROUS ION; HISTIDINE; WATER; ZINC ION; AMYLOID BETA-PROTEIN (1-42); COPPER; DIVALENT CATION; IRON; PEPTIDE FRAGMENT; PROTEIN AGGREGATE; ZINC;

AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BINDING AFFINITY; CONFORMATIONAL TRANSITION; DENSITY FUNCTIONAL THEORY; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; STRUCTURE ANALYSIS; ALPHA HELIX; CHEMICAL PHENOMENA; CHEMISTRY; HUMAN; QUANTUM THEORY; THERMODYNAMICS;

AMYLOID BETA-PEPTIDES; CATIONS, DIVALENT; COPPER; HISTIDINE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IRON; MOLECULAR DYNAMICS SIMULATION; PEPTIDE FRAGMENTS; PROTEIN AGGREGATES; PROTEIN CONFORMATION, ALPHA-HELICAL; PROTEIN CONFORMATION, BETA-STRAND; QUANTUM THEORY; THERMODYNAMICS; WATER; ZINC;

EID: 84973377131     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.25075     Document Type: Article

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