-
1
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai, T., Hasegawa, M., Akiyama, H., Ikeda, K., Nonaka, T., Mori, H., Mann, D., Tsuchiya, K., Yoshida, M., Hashizume, Y., and Oda, T. (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 351, 602-611
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
2
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann, M., Sampathu, D. M., Kwong, L. K., Truax, A. C., Micsenyi, M. C., Chou, T. T., Bruce, J., Schuck, T., Grossman, M., Clark, C. M., McCluskey, L. F., Miller, B. L., Masliah, E., Mackenzie, I. R., Feldman, H., Feiden, W., Kretzschmar, H. A., Trojanowski, J. Q., and Lee, V. M. (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314, 130-133
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.19
-
3
-
-
78751616191
-
TDP-43 regulates its mRNA levels through a negative feed-back loop
-
Ayala, Y. M., De Conti, L., Avendaño-Vázquez, S. E., Dhir, A., Romano, M., D'Ambrogio, A., Tollervey, J., Ule, J., Baralle, M., Buratti, E., and Baralle, F. E. (2011) TDP-43 regulates its mRNA levels through a negative feed-back loop. EMBO J. 30, 277-288
-
(2011)
EMBO J
, vol.30
, pp. 277-288
-
-
Ayala, Y.M.1
De Conti, L.2
Avendaño-Vázquez, S.E.3
Dhir, A.4
Romano, M.5
D'Ambrogio, A.6
Tollervey, J.7
Ule, J.8
Baralle, M.9
Buratti, E.10
Baralle, F.E.11
-
4
-
-
59549094064
-
Structural determinants of the cellular localization and shuttling of TDP-43
-
Ayala, Y. M., Zago, P., D'Ambrogio, A., Xu, Y. F., Petrucelli, L., Buratti, E., and Baralle, F. E. (2008) Structural determinants of the cellular localization and shuttling of TDP-43. J. Cell Sci. 121, 3778-3785
-
(2008)
J. Cell Sci.
, vol.121
, pp. 3778-3785
-
-
Ayala, Y.M.1
Zago, P.2
D'Ambrogio, A.3
Xu, Y.F.4
Petrucelli, L.5
Buratti, E.6
Baralle, F.E.7
-
5
-
-
38449102667
-
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
-
Buratti, E., and Baralle, F. E. (2008) Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease. Front. Biosci. 13, 867-878
-
(2008)
Front. Biosci
, vol.13
, pp. 867-878
-
-
Buratti, E.1
Baralle, F.E.2
-
6
-
-
0029066110
-
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
-
Ou, S. H., Wu, F., Harrich, D., García-Martínez, L. F., and Gaynor, R. B. (1995) Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J. Virol. 69, 3584-3596
-
(1995)
J. Virol.
, vol.69
, pp. 3584-3596
-
-
Ou, S.H.1
Wu, F.2
Harrich, D.3
García-Martínez, L.F.4
Gaynor, R.B.5
-
7
-
-
0037108967
-
Higher order arrangement of the eukaryotic nuclear bodies
-
Wang, I. F., Reddy, N. M., and Shen, C. K. (2002) Higher order arrangement of the eukaryotic nuclear bodies. Proc. Natl. Acad. Sci. U.S.A. 99, 13583-13588
-
(2002)
Proc. Natl. Acad. Sci. U.S.A
, vol.99
, pp. 13583-13588
-
-
Wang, I.F.1
Reddy, N.M.2
Shen, C.K.3
-
8
-
-
17144426507
-
Human, Drosophila, and C. Elegans TDP43: Nucleic acid binding properties and splicing regulatory function
-
Ayala, Y. M., Pantano, S., D'Ambrogio, A., Buratti, E., Brindisi, A., Marchetti, C., Romano, M., and Baralle, F. E. (2005) Human, Drosophila, and C. elegans TDP43: nucleic acid binding properties and splicing regulatory function. J. Mol. Biol. 348, 575-588
-
(2005)
J. Mol. Biol.
, vol.348
, pp. 575-588
-
-
Ayala, Y.M.1
Pantano, S.2
D'Ambrogio, A.3
Buratti, E.4
Brindisi, A.5
Marchetti, C.6
Romano, M.7
Baralle, F.E.8
-
9
-
-
0035965309
-
Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9
-
Buratti, E., and Baralle, F. E. (2001) Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9. J. Biol. Chem. 276, 36337-36343
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36337-36343
-
-
Buratti, E.1
Baralle, F.E.2
-
10
-
-
27844514227
-
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: An important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
-
Buratti, E., Brindisi, A., Giombi, M., Tisminetzky, S., Ayala, Y. M., and Baralle, F. E. (2005) TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. J. Biol. Chem. 280, 37572-37584
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37572-37584
-
-
Buratti, E.1
Brindisi, A.2
Giombi, M.3
Tisminetzky, S.4
Ayala, Y.M.5
Baralle, F.E.6
-
11
-
-
54249100481
-
TDP-43: An emerging new player in neurodegenerative diseases
-
Wang, I. F., Wu, L. S., and Shen, C. K. (2008) TDP-43: an emerging new player in neurodegenerative diseases. Trends Mol. Med. 14, 479-485
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 479-485
-
-
Wang, I.F.1
Wu, L.S.2
Shen, C.K.3
-
12
-
-
84939506533
-
Neurodegeneration: Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein
-
Goedert, M. (2015) Neurodegeneration: Alzheimer's and Parkinson's diseases: the prion concept in relation to assembled Aβ, tau, and α-synuclein. Science 349, 1255555
-
(2015)
Science
, vol.349
-
-
Goedert, M.1
-
13
-
-
47949086625
-
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Hasegawa, M., Arai, T., Nonaka, T., Kametani, F., Yoshida, M., Hashizume, Y., Beach, T. G., Buratti, E., Baralle, F., Morita, M., Nakano, I., Oda, T., Tsuchiya, K., and Akiyama, H. (2008) Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann. Neurol. 64, 60-70
-
(2008)
Ann. Neurol.
, vol.64
, pp. 60-70
-
-
Hasegawa, M.1
Arai, T.2
Nonaka, T.3
Kametani, F.4
Yoshida, M.5
Hashizume, Y.6
Beach, T.G.7
Buratti, E.8
Baralle, F.9
Morita, M.10
Nakano, I.11
Oda, T.12
Tsuchiya, K.13
Akiyama, H.14
-
14
-
-
74949135753
-
Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis
-
Barmada, S. J., Skibinski, G., Korb, E., Rao, E. J., Wu, J. Y., and Finkbeiner, S. (2010) Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis. J. Neurosci. 30, 639-649
-
(2010)
J. Neurosci
, vol.30
, pp. 639-649
-
-
Barmada, S.J.1
Skibinski, G.2
Korb, E.3
Rao, E.J.4
Wu, J.Y.5
Finkbeiner, S.6
-
15
-
-
67649797399
-
Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies
-
Igaz, L. M., Kwong, L. K., Chen-Plotkin, A., Winton, M. J., Unger, T. L., Xu, Y., Neumann, M., Trojanowski, J. Q., and Lee, V. M. (2009) Expression of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies. J. Biol. Chem. 284, 8516-8524
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 8516-8524
-
-
Igaz, L.M.1
Kwong, L.K.2
Chen-Plotkin, A.3
Winton, M.J.4
Unger, T.L.5
Xu, Y.6
Neumann, M.7
Trojanowski, J.Q.8
Lee, V.M.9
-
16
-
-
58149498300
-
Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells
-
Nonaka, T., Arai, T., Buratti, E., Baralle, F. E., Akiyama, H., and Hasegawa, M. (2009) Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells. FEBS Lett. 583, 394-400
-
(2009)
FEBS Lett.
, vol.583
, pp. 394-400
-
-
Nonaka, T.1
Arai, T.2
Buratti, E.3
Baralle, F.E.4
Akiyama, H.5
Hasegawa, M.6
-
17
-
-
67650113333
-
Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43
-
Nonaka, T., Kametani, F., Arai, T., Akiyama, H., and Hasegawa, M. (2009) Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43. Hum. Mol. Genet. 18, 3353-3364
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 3353-3364
-
-
Nonaka, T.1
Kametani, F.2
Arai, T.3
Akiyama, H.4
Hasegawa, M.5
-
18
-
-
44749091997
-
Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
-
Winton, M. J., Igaz, L. M., Wong, M. M., Kwong, L. K., Trojanowski, J. Q., and Lee, V. M. (2008) Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J. Biol. Chem. 283, 13302-13309
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13302-13309
-
-
Winton, M.J.1
Igaz, L.M.2
Wong, M.M.3
Kwong, L.K.4
Trojanowski, J.Q.5
Lee, V.M.6
-
19
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang, Y. J., Xu, Y. F., Cook, C., Gendron, T. F., Roettges, P., Link, C. D., Lin, W. L., Tong, J., Castanedes-Casey, M., Ash, P., Gass, J., Rangachari, V., Buratti, E., Baralle, F., Golde, T. E., Dickson, D. W., and Petrucelli, L. (2009) Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc. Natl. Acad. Sci. U.S.A. 106, 7607-7612
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.J.1
Xu, Y.F.2
Cook, C.3
Gendron, T.F.4
Roettges, P.5
Link, C.D.6
Lin, W.L.7
Tong, J.8
Castanedes-Casey, M.9
Ash, P.10
Gass, J.11
Rangachari, V.12
Buratti, E.13
Baralle, F.14
Golde, T.E.15
Dickson, D.W.16
Petrucelli, L.17
-
20
-
-
84897052708
-
Casein kinase II induced polymerization of soluble TDP-43 into filaments is inhibited by heat shock proteins
-
Carlomagno, Y., Zhang, Y., Davis, M., Lin, W. L., Cook, C., Dunmore, J., Tay, W., Menkosky, K., Cao, X., Petrucelli, L., and Deture, M. (2014) Casein kinase II induced polymerization of soluble TDP-43 into filaments is inhibited by heat shock proteins. PLoS ONE 9, e90452
-
(2014)
PLoS ONE
, vol.9
-
-
Carlomagno, Y.1
Zhang, Y.2
Davis, M.3
Lin, W.L.4
Cook, C.5
Dunmore, J.6
Tay, W.7
Menkosky, K.8
Cao, X.9
Petrucelli, L.10
Deture, M.11
-
21
-
-
84893012138
-
TDP-43 Phosphorylation by casein kinase I∈ promotes oligomerization and enhances toxicity in vivo
-
Choksi, D. K., Roy, B., Chatterjee, S., Yusuff, T., Bakhoum, M. F., Sengupta, U., Ambegaokar, S., Kayed, R., and Jackson, G. R. (2014) TDP-43 Phosphorylation by casein kinase I∈ promotes oligomerization and enhances toxicity in vivo. Hum. Mol. Genet. 23, 1025-1035
-
(2014)
Hum. Mol. Genet.
, vol.23
, pp. 1025-1035
-
-
Choksi, D.K.1
Roy, B.2
Chatterjee, S.3
Yusuff, T.4
Bakhoum, M.F.5
Sengupta, U.6
Ambegaokar, S.7
Kayed, R.8
Jackson, G.R.9
-
22
-
-
78649750391
-
Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy
-
Liachko, N. F., Guthrie, C. R., and Kraemer, B. C. (2010) Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy. J. Neurosci. 30, 16208-16219
-
(2010)
J. Neurosci
, vol.30
, pp. 16208-16219
-
-
Liachko, N.F.1
Guthrie, C.R.2
Kraemer, B.C.3
-
23
-
-
84883297079
-
CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration
-
Liachko, N. F., McMillan, P. J., Guthrie, C. R., Bird, T. D., Leverenz, J. B., and Kraemer, B. C. (2013) CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration. Ann. Neurol. 74, 39-52
-
(2013)
Ann. Neurol.
, vol.74
, pp. 39-52
-
-
Liachko, N.F.1
McMillan, P.J.2
Guthrie, C.R.3
Bird, T.D.4
Leverenz, J.B.5
Kraemer, B.C.6
-
24
-
-
84919663858
-
The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43
-
Liachko, N. F., McMillan, P. J., Strovas, T. J., Loomis, E., Greenup, L., Murrell, J. R., Ghetti, B., Raskind, M. A., Montine, T. J., Bird, T. D., Leverenz, J. B., and Kraemer, B. C. (2014) The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43. PLoS Genet. 10, e1004803
-
(2014)
PLoS Genet.
, vol.10
-
-
Liachko, N.F.1
McMillan, P.J.2
Strovas, T.J.3
Loomis, E.4
Greenup, L.5
Murrell, J.R.6
Ghetti, B.7
Raskind, M.A.8
Montine, T.J.9
Bird, T.D.10
Leverenz, J.B.11
Kraemer, B.C.12
-
25
-
-
48749088629
-
Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS
-
Inukai, Y., Nonaka, T., Arai, T., Yoshida, M., Hashizume, Y., Beach, T. G., Buratti, E., Baralle, F. E., Akiyama, H., Hisanaga, S., and Hasegawa, M. (2008) Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS. FEBS Lett. 582, 2899-2904
-
(2008)
FEBS Lett.
, vol.582
, pp. 2899-2904
-
-
Inukai, Y.1
Nonaka, T.2
Arai, T.3
Yoshida, M.4
Hashizume, Y.5
Beach, T.G.6
Buratti, E.7
Baralle, F.E.8
Akiyama, H.9
Hisanaga, S.10
Hasegawa, M.11
-
26
-
-
78049376559
-
Seeded aggregation and toxicity of α-synuclein and tau: Cellular models of neurodegenerative diseases
-
Nonaka, T., Watanabe, S. T., Iwatsubo, T., and Hasegawa, M. (2010) Seeded aggregation and toxicity of α-synuclein and tau: cellular models of neurodegenerative diseases. J. Biol. Chem. 285, 34885-34898
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34885-34898
-
-
Nonaka, T.1
Watanabe, S.T.2
Iwatsubo, T.3
Hasegawa, M.4
-
27
-
-
0029131396
-
Role of COOH-terminal phosphorylation in the regulation of casein kinase I δ
-
Graves, P. R., and Roach, P. J. (1995) Role of COOH-terminal phosphorylation in the regulation of casein kinase I δ. J. Biol. Chem. 270, 21689-21694
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 21689-21694
-
-
Graves, P.R.1
Roach, P.J.2
-
28
-
-
1942469505
-
Casein kinase 1 δ phosphorylates tau and disrupts its binding to microtubules
-
Li, G., Yin, H., and Kuret, J. (2004) Casein kinase 1 δ phosphorylates tau and disrupts its binding to microtubules. J. Biol. Chem. 279, 15938-15945
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 15938-15945
-
-
Li, G.1
Yin, H.2
Kuret, J.3
-
29
-
-
79959570401
-
Molecular mechanism of activation of human Cdc7 kinase: Bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition
-
Kitamura, R., Fukatsu, R., Kakusho, N., Cho, Y. S., Taniyama, C., Yamazaki, S., Toh, G. T., Yanagi, K., Arai, N., Chang, H. J., and Masai, H. (2011) Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition. J. Biol. Chem. 286, 23031-23043
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 23031-23043
-
-
Kitamura, R.1
Fukatsu, R.2
Kakusho, N.3
Cho, Y.S.4
Taniyama, C.5
Yamazaki, S.6
Toh, G.T.7
Yanagi, K.8
Arai, N.9
Chang, H.J.10
Masai, H.11
-
30
-
-
84902449696
-
Regulation and roles of Cdc7 kinase under replication stress
-
Yamada, M., Masai, H., and Bartek, J. (2014) Regulation and roles of Cdc7 kinase under replication stress. Cell Cycle 13, 1859-1866
-
(2014)
Cell Cycle
, vol.13
, pp. 1859-1866
-
-
Yamada, M.1
Masai, H.2
Bartek, J.3
-
31
-
-
0035794665
-
Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping
-
Buratti, E., Dörk, T., Zuccato, E., Pagani, F., Romano, M., and Baralle, F. E. (2001) Nuclear factor TDP-43 and SR proteins promote in vitro and in vivo CFTR exon 9 skipping. EMBO J. 20, 1774-1784
-
(2001)
EMBO J
, vol.20
, pp. 1774-1784
-
-
Buratti, E.1
Dörk, T.2
Zuccato, E.3
Pagani, F.4
Romano, M.5
Baralle, F.E.6
-
32
-
-
75649135319
-
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
-
Fiesel, F. C., Voigt, A., Weber, S. S., Van den Haute, C., Waldenmaier, A., Görner, K., Walter, M., Anderson, M. L., Kern, J. V., Rasse, T. M., Schmidt, T., Springer, W., Kirchner, R., Bonin, M., Neumann, M., Baekelandt, V., Alunni-Fabbroni, M., Schulz, J. B., and Kahle, P. J. (2010) Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J. 29, 209-221
-
(2010)
EMBO J
, vol.29
, pp. 209-221
-
-
Fiesel, F.C.1
Voigt, A.2
Weber, S.S.3
Van Den Haute, C.4
Waldenmaier, A.5
Görner, K.6
Walter, M.7
Anderson, M.L.8
Kern, J.V.9
Rasse, T.M.10
Schmidt, T.11
Springer, W.12
Kirchner, R.13
Bonin, M.14
Neumann, M.15
Baekelandt, V.16
Alunni-Fabbroni, M.17
Schulz, J.B.18
Kahle, P.J.19
-
33
-
-
67650088244
-
Casein kinase 1 δ regulates the pace of the mammalian circadian clock
-
Etchegaray, J. P., Machida, K. K., Noton, E., Constance, C. M., Dallmann, R., Di Napoli, M. N., DeBruyne, J. P., Lambert, C. M., Yu, E. A., Reppert, S. M., and Weaver, D. R. (2009) Casein kinase 1 δ regulates the pace of the mammalian circadian clock. Mol. Cell. Biol. 29, 3853-3866
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 3853-3866
-
-
Etchegaray, J.P.1
Machida, K.K.2
Noton, E.3
Constance, C.M.4
Dallmann, R.5
Di Napoli, M.N.6
DeBruyne, J.P.7
Lambert, C.M.8
Yu, E.A.9
Reppert, S.M.10
Weaver, D.R.11
-
34
-
-
79960040173
-
An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity
-
Guo, W., Chen, Y., Zhou, X., Kar, A., Ray, P., Chen, X., Rao, E. J., Yang, M., Ye, H., Zhu, L., Liu, J., Xu, M., Yang, Y., Wang, C., Zhang, D., Bigio, E. H., Mesulam, M., Shen, Y., Xu, Q., Fushimi, K., and Wu, J. Y. (2011) An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity. Nat. Struct. Mol. Biol. 18, 822-830
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 822-830
-
-
Guo, W.1
Chen, Y.2
Zhou, X.3
Kar, A.4
Ray, P.5
Chen, X.6
Rao, E.J.7
Yang, M.8
Ye, H.9
Zhu, L.10
Liu, J.11
Xu, M.12
Yang, Y.13
Wang, C.14
Zhang, D.15
Bigio, E.H.16
Mesulam, M.17
Shen, Y.18
Xu, Q.19
Fushimi, K.20
Wu, J.Y.21
more..
-
35
-
-
84920901644
-
Conformation determines the seeding potencies of native and recombinant Tau aggregates
-
Falcon, B., Cavallini, A., Angers, R., Glover, S., Murray, T. K., Barnham, L., Jackson, S., O'Neill, M. J., Isaacs, A. M., Hutton, M. L., Szekeres, P. G., Goedert, M., and Bose, S. (2015) Conformation determines the seeding potencies of native and recombinant Tau aggregates. J. Biol. Chem. 290, 1049-1065
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 1049-1065
-
-
Falcon, B.1
Cavallini, A.2
Angers, R.3
Glover, S.4
Murray, T.K.5
Barnham, L.6
Jackson, S.7
O'Neill, M.J.8
Isaacs, A.M.9
Hutton, M.L.10
Szekeres, P.G.11
Goedert, M.12
Bose, S.13
-
36
-
-
67649273927
-
Propagation of tau misfolding from the outside to the inside of a cell
-
Frost, B., Jacks, R. L., and Diamond, M. I. (2009) Propagation of tau misfolding from the outside to the inside of a cell. J. Biol. Chem. 284, 12845-12852
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 12845-12852
-
-
Frost, B.1
Jacks, R.L.2
Diamond, M.I.3
-
37
-
-
77954385676
-
The propagation of prion-like protein inclusions in neurodegenerative diseases
-
Goedert, M., Clavaguera, F., and Tolnay, M. (2010) The propagation of prion-like protein inclusions in neurodegenerative diseases. Trends Neurosci. 33, 317-325
-
(2010)
Trends Neurosci
, vol.33
, pp. 317-325
-
-
Goedert, M.1
Clavaguera, F.2
Tolnay, M.3
-
38
-
-
84869109864
-
Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
-
Luk, K. C., Kehm, V., Carroll, J., Zhang, B., O'Brien, P., Trojanowski, J. Q., and Lee, V. M. (2012) Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice. Science 338, 949-953
-
(2012)
Science
, vol.338
, pp. 949-953
-
-
Luk, K.C.1
Kehm, V.2
Carroll, J.3
Zhang, B.4
O'Brien, P.5
Trojanowski, J.Q.6
Lee, V.M.7
-
39
-
-
84862609075
-
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
-
Luk, K. C., Kehm, V. M., Zhang, B., O'Brien, P., Trojanowski, J. Q., and Lee, V. M. (2012) Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice. J. Exp. Med. 209, 975-986
-
(2012)
J. Exp. Med.
, vol.209
, pp. 975-986
-
-
Luk, K.C.1
Kehm, V.M.2
Zhang, B.3
O'Brien, P.4
Trojanowski, J.Q.5
Lee, V.M.6
-
40
-
-
72149119358
-
Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
-
Luk, K. C., Song, C., O'Brien, P., Stieber, A., Branch, J. R., Brunden, K. R., Trojanowski, J. Q., and Lee, V. M. (2009) Exogenous α-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells. Proc. Natl. Acad. Sci. U.S.A. 106, 20051-20056
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 20051-20056
-
-
Luk, K.C.1
Song, C.2
O'Brien, P.3
Stieber, A.4
Branch, J.R.5
Brunden, K.R.6
Trojanowski, J.Q.7
Lee, V.M.8
-
41
-
-
85048243758
-
Pathological α-synuclein propagates through neural networks
-
Masuda-Suzukake, M., Nonaka, T., Hosokawa, M., Kubo, M., Shimozawa, A., Akiyama, H., and Hasegawa, M. (2014) Pathological α-synuclein propagates through neural networks. Acta Neuropathol. Commun. 2, 88
-
(2014)
Acta Neuropathol. Commun.
, vol.2
, pp. 88
-
-
Masuda-Suzukake, M.1
Nonaka, T.2
Hosokawa, M.3
Kubo, M.4
Shimozawa, A.5
Akiyama, H.6
Hasegawa, M.7
-
42
-
-
84876057762
-
Prion-like spreading of pathological α-synuclein in brain
-
Masuda-Suzukake, M., Nonaka, T., Hosokawa, M., Oikawa, T., Arai, T., Akiyama, H., Mann, D. M., and Hasegawa, M. (2013) Prion-like spreading of pathological α-synuclein in brain. Brain 136, 1128-1138
-
(2013)
Brain
, vol.136
, pp. 1128-1138
-
-
Masuda-Suzukake, M.1
Nonaka, T.2
Hosokawa, M.3
Oikawa, T.4
Arai, T.5
Akiyama, H.6
Mann, D.M.7
Hasegawa, M.8
-
43
-
-
84885484356
-
Prion-like properties of pathological TDP-43 aggregates from diseased brains
-
Nonaka, T., Masuda-Suzukake, M., Arai, T., Hasegawa, Y., Akatsu, H., Obi, T., Yoshida, M., Murayama, S., Mann, D. M., Akiyama, H., and Hasegawa, M. (2013) Prion-like properties of pathological TDP-43 aggregates from diseased brains. Cell Rep 4, 124-134
-
(2013)
Cell Rep
, vol.4
, pp. 124-134
-
-
Nonaka, T.1
Masuda-Suzukake, M.2
Arai, T.3
Hasegawa, Y.4
Akatsu, H.5
Obi, T.6
Yoshida, M.7
Murayama, S.8
Mann, D.M.9
Akiyama, H.10
Hasegawa, M.11
|