메뉴 건너뛰기




Volumn 145, Issue , 2016, Pages 197-206

Metabolic profiling of potential lung cancer biomarkers using bronchoalveolar lavage fluid and the integrated direct infusion/ gas chromatography mass spectrometry platform

Author keywords

Biomarkers; Bronchoalveolar fluid; Direct infusion mass spectrometry; Gas chromatography mass spectrometry; Lung cancer; Metabolomics

Indexed keywords

ACETIC ACID; ACETYLCARNITINE; ACETYLCHOLINE; ADENINE; ARGININE; BENZOIC ACID; CARNITINE; CHOLINE; CREATINE; GALACTOSE; GLUTAMIC ACID; GLUTAMINE; GLYCEROL; GLYCEROPHOSPHORYLCHOLINE; INOSINE; ISOCITRIC ACID; LACTIC ACID; LYSOPHOSPHOLIPID; OLEIC ACID; PALMITIC ACID; PHOSPHOETHANOLAMINE; PHOSPHORIC ACID; PHOSPHORYLCHOLINE; PLASMALOGEN; PYROGLUTAMIC ACID; SERINE; STEARIC ACID; TUMOR MARKER; UREA; VALINE;

EID: 84973171653     PISSN: 18743919     EISSN: 18767737     Source Type: Journal    
DOI: 10.1016/j.jprot.2016.05.030     Document Type: Article
Times cited : (63)

References (62)
  • 1
    • 84871036375 scopus 로고    scopus 로고
    • Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study 2010
    • [1] Lozano, R., Naghavi, M., Foreman, K., Lim, S., Shibuya, K., Aboyans, V., et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the global burden of disease study 2010. Lancet 380 (2012), 2095–2128, 10.1016/S0140-6736(12)61728-0.
    • (2012) Lancet , vol.380 , pp. 2095-2128
    • Lozano, R.1    Naghavi, M.2    Foreman, K.3    Lim, S.4    Shibuya, K.5    Aboyans, V.6
  • 3
    • 84925516170 scopus 로고    scopus 로고
    • Metabolomic Profiling of Human Serum in Lung Cancer Patients Using Liquid Chromatography / Hybrid Quadrupole Time-of-Flight Mass Spectrometry and Gas Chromatography / Mass Spectrometry
    • [3] Chen, Y., Ma, Z., Li, A., Li, H., Wang, B., Zhong, J., et al. Metabolomic Profiling of Human Serum in Lung Cancer Patients Using Liquid Chromatography / Hybrid Quadrupole Time-of-Flight Mass Spectrometry and Gas Chromatography / Mass Spectrometry. 2015, 705–718, 10.1007/s00432–014–1846-5.
    • (2015) , pp. 705-718
    • Chen, Y.1    Ma, Z.2    Li, A.3    Li, H.4    Wang, B.5    Zhong, J.6
  • 4
    • 82755177807 scopus 로고    scopus 로고
    • Diagnosis of lung cancer based on direct-infusion electrospray mass spectrometry of blood plasma metabolites
    • [4] Lokhov, P.G., Kharybin, O.N., Archakov, A.I., Diagnosis of lung cancer based on direct-infusion electrospray mass spectrometry of blood plasma metabolites. Int. J. Mass Spectrom. 309 (2012), 200–205, 10.1016/j.ijms.2011.10.002.
    • (2012) Int. J. Mass Spectrom. , vol.309 , pp. 200-205
    • Lokhov, P.G.1    Kharybin, O.N.2    Archakov, A.I.3
  • 5
    • 80053636773 scopus 로고    scopus 로고
    • Serum discrimination of early-stage lung cancer patients using electrospray-ionization mass spectrometry
    • [5] Hocker, J.R., Peyton, M.D., Lerner, M.R., Mitchell, S.L., Lightfoot, S.A., Lander, T.J., et al. Serum discrimination of early-stage lung cancer patients using electrospray-ionization mass spectrometry. Lung Cancer 74 (2011), 206–211, 10.1016/j.lungcan.2011.03.014.
    • (2011) Lung Cancer , vol.74 , pp. 206-211
    • Hocker, J.R.1    Peyton, M.D.2    Lerner, M.R.3    Mitchell, S.L.4    Lightfoot, S.A.5    Lander, T.J.6
  • 8
    • 84881089210 scopus 로고    scopus 로고
    • Exploratory investigation of plasma metabolomics in human lung adenocarcinoma
    • [8] Wen, T., Gao, L., Wen, Z., Wu, C., Tan, C.S., Toh, W.Z., et al. Exploratory investigation of plasma metabolomics in human lung adenocarcinoma. Mol. BioSyst. 9 (2013), 2370–2378, 10.1039/c3mb70138g.
    • (2013) Mol. BioSyst. , vol.9 , pp. 2370-2378
    • Wen, T.1    Gao, L.2    Wen, Z.3    Wu, C.4    Tan, C.S.5    Toh, W.Z.6
  • 9
    • 1542268299 scopus 로고    scopus 로고
    • Metabonomics and its role in drug development and disease diagnosis
    • [9] Lindon, J.C., Holmes, E., Nicholson, J.K., Metabonomics and its role in drug development and disease diagnosis. Expert. Rev. Mol. Diagn. 4 (2004), 189–199, 10.1586/14737159.4.2.189.
    • (2004) Expert. Rev. Mol. Diagn. , vol.4 , pp. 189-199
    • Lindon, J.C.1    Holmes, E.2    Nicholson, J.K.3
  • 10
    • 0035913738 scopus 로고    scopus 로고
    • Biochemical analysis using high-resolution magic angle spinning NMR spectroscopy distinguishes lipoma-like well-differentiated liposarcoma from normal fat
    • [10] Chen, J.-H., Enloe, B.M., Fletcher, C.D., Cory, D.G., Singer, S., Biochemical analysis using high-resolution magic angle spinning NMR spectroscopy distinguishes lipoma-like well-differentiated liposarcoma from normal fat. J. Am. Chem. Soc. 123 (2001), 9200–9201, 10.1021/ja016182u.
    • (2001) J. Am. Chem. Soc. , vol.123 , pp. 9200-9201
    • Chen, J.-H.1    Enloe, B.M.2    Fletcher, C.D.3    Cory, D.G.4    Singer, S.5
  • 11
    • 33646123072 scopus 로고    scopus 로고
    • Capillary electrophoresis in metabolomics
    • [11] Ramautar, R., Demirci, A., de Jong, G.J., Capillary electrophoresis in metabolomics. TrAC Trends Anal. Chem. 25 (2006), 455–466, 10.1016/j.trac.2006.02.004.
    • (2006) TrAC Trends Anal. Chem. , vol.25 , pp. 455-466
    • Ramautar, R.1    Demirci, A.2    de Jong, G.J.3
  • 12
    • 84876973252 scopus 로고    scopus 로고
    • Ultra high performance liquid chromatography tandem mass spectrometry determination and profiling of prohibited steroids in human biological matrices. A review
    • [12] Gosetti, F., Mazzucco, E., Gennaro, M.C., Marengo, E., Ultra high performance liquid chromatography tandem mass spectrometry determination and profiling of prohibited steroids in human biological matrices. A review. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 927 (2013), 22–36, 10.1016/j.jchromb.2012.12.003.
    • (2013) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.927 , pp. 22-36
    • Gosetti, F.1    Mazzucco, E.2    Gennaro, M.C.3    Marengo, E.4
  • 13
    • 84990002815 scopus 로고    scopus 로고
    • Preliminary results of metabolite in serum and urine of lung cancer patients detected by metabolomics
    • [13] Niu, Y., Jiang, Y., Xu, C., Wang, X., Liu, Y., Zhao, H., et al. Preliminary results of metabolite in serum and urine of lung cancer patients detected by metabolomics. Zhongguo Fei Ai Za Zhi 15 (2012), 195–201, 10.3779/j.issn.1009-3419.2012.04.01.
    • (2012) Zhongguo Fei Ai Za Zhi , vol.15 , pp. 195-201
    • Niu, Y.1    Jiang, Y.2    Xu, C.3    Wang, X.4    Liu, Y.5    Zhao, H.6
  • 14
    • 84919742683 scopus 로고    scopus 로고
    • Using direct infusion mass spectrometry for serum metabolomics in Alzheimer's disease
    • [14] González-Domínguez, R., García-Barrera, T., Gómez-Ariza, J.L., Using direct infusion mass spectrometry for serum metabolomics in Alzheimer's disease. Anal. Bioanal. Chem. 406 (2014), 7137–7148, 10.1007/s00216-014-8102-3.
    • (2014) Anal. Bioanal. Chem. , vol.406 , pp. 7137-7148
    • González-Domínguez, R.1    García-Barrera, T.2    Gómez-Ariza, J.L.3
  • 15
    • 84874393708 scopus 로고    scopus 로고
    • Flow infusion electrospray ionisation mass spectrometry for high throughput, non-targeted metabolite fingerprinting: a review
    • [15] Draper, J., Lloyd, A.J., Goodacre, R., Beckmann, M., Flow infusion electrospray ionisation mass spectrometry for high throughput, non-targeted metabolite fingerprinting: a review. Metabolomics 9 (2012), 4–29, 10.1007/s11306-012-0449-x.
    • (2012) Metabolomics , vol.9 , pp. 4-29
    • Draper, J.1    Lloyd, A.J.2    Goodacre, R.3    Beckmann, M.4
  • 16
    • 84903640571 scopus 로고    scopus 로고
    • Metabolomic study of lipids in serum for biomarker discovery in Alzheimer's disease using direct infusion mass spectrometry
    • [16] González-Domínguez, R., García-Barrera, T., Gómez-Ariza, J.L., Metabolomic study of lipids in serum for biomarker discovery in Alzheimer's disease using direct infusion mass spectrometry. J. Pharm. Biomed. Anal. 98 (2014), 321–326, 10.1016/j.jpba.2014.05.023.
    • (2014) J. Pharm. Biomed. Anal. , vol.98 , pp. 321-326
    • González-Domínguez, R.1    García-Barrera, T.2    Gómez-Ariza, J.L.3
  • 17
    • 49049100226 scopus 로고    scopus 로고
    • Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry
    • [17] Takahashi, H., Kai, K., Shinbo, Y., Tanaka, K., Ohta, D., Oshima, T., et al. Metabolomics approach for determining growth-specific metabolites based on Fourier transform ion cyclotron resonance mass spectrometry. Anal. Bioanal. Chem. 391 (2008), 2769–2782, 10.1007/s00216-008-2195-5.
    • (2008) Anal. Bioanal. Chem. , vol.391 , pp. 2769-2782
    • Takahashi, H.1    Kai, K.2    Shinbo, Y.3    Tanaka, K.4    Ohta, D.5    Oshima, T.6
  • 18
    • 84856230471 scopus 로고    scopus 로고
    • Cord blood metabolomic profiling in intrauterine growth restriction
    • [18] Favretto, D., Cosmi, E., Ragazzi, E., Visentin, S., Tucci, M., Fais, P., et al. Cord blood metabolomic profiling in intrauterine growth restriction. Anal. Bioanal. Chem. 402 (2012), 1109–1121, 10.1007/s00216-011-5540-z.
    • (2012) Anal. Bioanal. Chem. , vol.402 , pp. 1109-1121
    • Favretto, D.1    Cosmi, E.2    Ragazzi, E.3    Visentin, S.4    Tucci, M.5    Fais, P.6
  • 19
    • 84866496952 scopus 로고    scopus 로고
    • Probing gender-specific lipid metabolites and diagnostic biomarkers for lung cancer using Fourier transform ion cyclotron resonance mass spectrometry
    • [19] Guo, Y., Wang, X., Qiu, L., Qin, X., Liu, H., Wang, Y., et al. Probing gender-specific lipid metabolites and diagnostic biomarkers for lung cancer using Fourier transform ion cyclotron resonance mass spectrometry. Clin. Chim. Acta 414 (2012), 135–141, 10.1016/j.cca.2012.08.010.
    • (2012) Clin. Chim. Acta , vol.414 , pp. 135-141
    • Guo, Y.1    Wang, X.2    Qiu, L.3    Qin, X.4    Liu, H.5    Wang, Y.6
  • 20
    • 78650314877 scopus 로고    scopus 로고
    • Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study
    • [20] Maeda, J., Higashiyama, M., Imaizumi, A., Nakayama, T., Yamamoto, H., Daimon, T., et al. Possibility of multivariate function composed of plasma amino acid profiles as a novel screening index for non-small cell lung cancer: a case control study. BMC Cancer, 10, 2010, 690, 10.1186/1471-2407-10-690.
    • (2010) BMC Cancer , vol.10 , pp. 690
    • Maeda, J.1    Higashiyama, M.2    Imaizumi, A.3    Nakayama, T.4    Yamamoto, H.5    Daimon, T.6
  • 21
    • 79951518482 scopus 로고    scopus 로고
    • Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine
    • [21] Carrola, J., Rocha, C.M., Barros, A.S., Gil, A.M., Goodfellow, B.J., Carreira, I.M., et al. Metabolic signatures of lung cancer in biofluids: NMR-based metabonomics of urine. J. Proteome Res. 10 (2011), 221–230, 10.1021/pr100899x.
    • (2011) J. Proteome Res. , vol.10 , pp. 221-230
    • Carrola, J.1    Rocha, C.M.2    Barros, A.S.3    Gil, A.M.4    Goodfellow, B.J.5    Carreira, I.M.6
  • 23
    • 77952792141 scopus 로고    scopus 로고
    • Urinary metabonomic study of lung cancer by a fully automatic hyphenated hydrophilic interaction/RPLC-MS system
    • [23] Yang, Q., Shi, X., Wang, Y., Wang, W., He, H., Lu, X., et al. Urinary metabonomic study of lung cancer by a fully automatic hyphenated hydrophilic interaction/RPLC-MS system. J. Sep. Sci. 33 (2010), 1495–1503, 10.1002/jssc.200900798.
    • (2010) J. Sep. Sci. , vol.33 , pp. 1495-1503
    • Yang, Q.1    Shi, X.2    Wang, Y.3    Wang, W.4    He, H.5    Lu, X.6
  • 24
    • 84881071578 scopus 로고    scopus 로고
    • Proteomic analysis of non-small cell lung cancer tissue interstitial fluids
    • [24] Li, S., Wang, R., Zhang, M., Wang, L., Cheng, S., Proteomic analysis of non-small cell lung cancer tissue interstitial fluids. World J. Surg. Oncol., 11, 2013, 173, 10.1186/1477-7819-11-173.
    • (2013) World J. Surg. Oncol. , vol.11 , pp. 173
    • Li, S.1    Wang, R.2    Zhang, M.3    Wang, L.4    Cheng, S.5
  • 25
    • 77649187288 scopus 로고    scopus 로고
    • Comparison of squamous cell carcinoma and adenocarcinoma of the lung by metabolomic analysis of tissue-serum pairs
    • [25] Jordan, K.W., Adkins, C.B., Su, L., Halpern, E.F., Mark, E.J., Christiani, D.C., et al. Comparison of squamous cell carcinoma and adenocarcinoma of the lung by metabolomic analysis of tissue-serum pairs. Lung Cancer 68 (2010), 44–50, 10.1016/j.lungcan.2009.05.012.
    • (2010) Lung Cancer , vol.68 , pp. 44-50
    • Jordan, K.W.1    Adkins, C.B.2    Su, L.3    Halpern, E.F.4    Mark, E.J.5    Christiani, D.C.6
  • 26
    • 73649147390 scopus 로고    scopus 로고
    • Metabolic profiling of human lung cancer tissue by 1H high resolution magic angle spinning (HRMAS) NMR spectroscopy
    • [26] Rocha, C.M., Barros, A.S., Gil, A.M., Goodfellow, B.J., Humpfer, E., Spraul, M., et al. Metabolic profiling of human lung cancer tissue by 1H high resolution magic angle spinning (HRMAS) NMR spectroscopy. J. Proteome Res. 9 (2010), 319–332, 10.1021/pr9006574.
    • (2010) J. Proteome Res. , vol.9 , pp. 319-332
    • Rocha, C.M.1    Barros, A.S.2    Gil, A.M.3    Goodfellow, B.J.4    Humpfer, E.5    Spraul, M.6
  • 27
    • 19044398693 scopus 로고    scopus 로고
    • Técnicas fibrobroncoscópicas especiales: lavado broncoalveolar, biopsia bronquial y biopsia transbronquial
    • [27] Escribano Montaner, A., Moreno Galdó, A., Técnicas fibrobroncoscópicas especiales: lavado broncoalveolar, biopsia bronquial y biopsia transbronquial. An. Pediatr. 62 (2005), 352–366, 10.1157/13073249.
    • (2005) An. Pediatr. , vol.62 , pp. 352-366
    • Escribano Montaner, A.1    Moreno Galdó, A.2
  • 28
    • 84905371232 scopus 로고    scopus 로고
    • Metabolomics reveals inflammatory-linked pulmonary metabolic alterations in a murine model of house dust mite-induced allergic asthma
    • [28] Ho, W.E., Xu, Y.-J., Cheng, C., Peh, H.Y., Tannenbaum, S.R., Wong, W.S.F., et al. Metabolomics reveals inflammatory-linked pulmonary metabolic alterations in a murine model of house dust mite-induced allergic asthma. J. Proteome Res. 13 (2014), 3771–3782, 10.1021/pr5003615.
    • (2014) J. Proteome Res. , vol.13 , pp. 3771-3782
    • Ho, W.E.1    Xu, Y.-J.2    Cheng, C.3    Peh, H.Y.4    Tannenbaum, S.R.5    Wong, W.S.F.6
  • 29
    • 38049148476 scopus 로고    scopus 로고
    • Microbes and metals: interactions in the environment
    • [29] Haferburg, G., Kothe, E., Microbes and metals: interactions in the environment. J. Basic Microbiol. 47 (2007), 453–467, 10.1002/jobm.200700275.
    • (2007) J. Basic Microbiol. , vol.47 , pp. 453-467
    • Haferburg, G.1    Kothe, E.2
  • 30
    • 84893854125 scopus 로고    scopus 로고
    • Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health
    • [30] Evans, C.R., Karnovsky, A., Kovach, M.A., Standiford, T.J., Burant, C.F., Stringer, K.A., Untargeted LC-MS metabolomics of bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health. J. Proteome Res. 13 (2014), 640–649, 10.1021/pr4007624.
    • (2014) J. Proteome Res. , vol.13 , pp. 640-649
    • Evans, C.R.1    Karnovsky, A.2    Kovach, M.A.3    Standiford, T.J.4    Burant, C.F.5    Stringer, K.A.6
  • 31
    • 84877618376 scopus 로고    scopus 로고
    • Metabolic profiling in human lung injuries by high-resolution nuclear magnetic resonance spectroscopy of bronchoalveolar lavage fluid (BALF)
    • [31] Rai, R.K., Azim, A., Sinha, N., Sahoo, J.N., Singh, C., Ahmed, A., et al. Metabolic profiling in human lung injuries by high-resolution nuclear magnetic resonance spectroscopy of bronchoalveolar lavage fluid (BALF). Metabolomics 9 (2012), 667–676, 10.1007/s11306-012-0472-y.
    • (2012) Metabolomics , vol.9 , pp. 667-676
    • Rai, R.K.1    Azim, A.2    Sinha, N.3    Sahoo, J.N.4    Singh, C.5    Ahmed, A.6
  • 32
    • 84902125525 scopus 로고    scopus 로고
    • Metabolomics of bronchoalveolar lavage differentiate healthy HIV-1-infected subjects from controls
    • [32] Park, Y., Guidot, D.M., Martin, G.S., Brown, L.A., Lennox, J., Jones, D.P., Metabolomics of bronchoalveolar lavage differentiate healthy HIV-1-infected subjects from controls. AIDS Res. Hum. Retrovir. 30 (2014), 579–585, 10.1089/aid.2013.0198.
    • (2014) AIDS Res. Hum. Retrovir. , vol.30 , pp. 579-585
    • Park, Y.1    Guidot, D.M.2    Martin, G.S.3    Brown, L.A.4    Lennox, J.5    Jones, D.P.6
  • 33
    • 66149145894 scopus 로고    scopus 로고
    • Metabolomic analysis of bronchoalveolar lavage fluid from cystic fibrosis patients
    • [33] Wolak, J.E., Esther, C.R., O'Connell, T.M., Metabolomic analysis of bronchoalveolar lavage fluid from cystic fibrosis patients. Biomarkers 14 (2009), 55–60, 10.1080/13547500802688194.
    • (2009) Biomarkers , vol.14 , pp. 55-60
    • Wolak, J.E.1    Esther, C.R.2    O'Connell, T.M.3
  • 34
    • 34347405493 scopus 로고    scopus 로고
    • Data processing for mass spectrometry-based metabolomics
    • [34] Katajamaa, M., Oresic, M., Data processing for mass spectrometry-based metabolomics. J. Chromatogr. A 1158 (2007), 318–328, 10.1016/j.chroma.2007.04.021.
    • (2007) J. Chromatogr. A , vol.1158 , pp. 318-328
    • Katajamaa, M.1    Oresic, M.2
  • 35
    • 32444446805 scopus 로고    scopus 로고
    • XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification
    • [35] Smith, C.A., Want, E.J., O'Maille, G., Abagyan, R., Siuzdak, G., XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal. Chem. 78 (2006), 779–787, 10.1021/ac051437y.
    • (2006) Anal. Chem. , vol.78 , pp. 779-787
    • Smith, C.A.1    Want, E.J.2    O'Maille, G.3    Abagyan, R.4    Siuzdak, G.5
  • 36
    • 79961006349 scopus 로고    scopus 로고
    • Optimized preprocessing of ultra-performance liquid chromatography/mass spectrometry urinary metabolic profiles for improved information recovery
    • [36] Veselkov, K.A., Vingara, L.K., Masson, P., Robinette, S.L., Want, E., Li, J.V., et al. Optimized preprocessing of ultra-performance liquid chromatography/mass spectrometry urinary metabolic profiles for improved information recovery. Anal. Chem. 83 (2011), 5864–5872, 10.1021/ac201065j.
    • (2011) Anal. Chem. , vol.83 , pp. 5864-5872
    • Veselkov, K.A.1    Vingara, L.K.2    Masson, P.3    Robinette, S.L.4    Want, E.5    Li, J.V.6
  • 37
    • 33747019547 scopus 로고    scopus 로고
    • Centering, scaling, and transformations: improving the biological information content of metabolomics data
    • [37] van den Berg, R.A., Hoefsloot, H.C.J., Westerhuis, J.A., Smilde, A.K., van der Werf, M.J., Centering, scaling, and transformations: improving the biological information content of metabolomics data. BMC Genomics, 7, 2006, 142, 10.1186/1471-2164-7-142.
    • (2006) BMC Genomics , vol.7 , pp. 142
    • van den Berg, R.A.1    Hoefsloot, H.C.J.2    Westerhuis, J.A.3    Smilde, A.K.4    van der Werf, M.J.5
  • 38
    • 77956550520 scopus 로고    scopus 로고
    • MetPA: a web-based metabolomics tool for pathway analysis and visualization
    • [38] Xia, J., Wishart, D.S., MetPA: a web-based metabolomics tool for pathway analysis and visualization. Bioinformatics 26 (2010), 2342–2344, 10.1093/bioinformatics/btq418.
    • (2010) Bioinformatics , vol.26 , pp. 2342-2344
    • Xia, J.1    Wishart, D.S.2
  • 39
    • 0029045178 scopus 로고
    • Plasma amino acid imbalance in patients with lung and breast cancer
    • [39] Cascino, A., Muscaritoli, M., Cangiano, C., Conversano, L., Laviano, A., Ariemma, S., et al. Plasma amino acid imbalance in patients with lung and breast cancer. Anticancer Res. 15 (1995), 507–510 (http://www.scopus.com/inward/record.url?eid=2-s2.0-0029045178&partnerID=tZOtx3y1).
    • (1995) Anticancer Res. , vol.15 , pp. 507-510
    • Cascino, A.1    Muscaritoli, M.2    Cangiano, C.3    Conversano, L.4    Laviano, A.5    Ariemma, S.6
  • 40
    • 0038078469 scopus 로고    scopus 로고
    • Breast and lung cancer are associated with a decrease in blood cell amino acid content
    • [40] Proenza, A.M., Oliver, J., Palou, A., Roca, P., Breast and lung cancer are associated with a decrease in blood cell amino acid content. J. Nutr. Biochem. 14 (2003), 133–138, 10.1016/S0955-2863(02)00225-5.
    • (2003) J. Nutr. Biochem. , vol.14 , pp. 133-138
    • Proenza, A.M.1    Oliver, J.2    Palou, A.3    Roca, P.4
  • 41
    • 23044469168 scopus 로고    scopus 로고
    • Plasma free amino acid profile in cancer patients
    • [41] Lai, H.-S., Lee, J.-C., Lee, P.-H., Wang, S.-T., Chen, W.-J., Plasma free amino acid profile in cancer patients. Semin. Cancer Biol. 15 (2005), 267–276, 10.1016/j.semcancer.2005.04.003.
    • (2005) Semin. Cancer Biol. , vol.15 , pp. 267-276
    • Lai, H.-S.1    Lee, J.-C.2    Lee, P.-H.3    Wang, S.-T.4    Chen, W.-J.5
  • 42
    • 0026529517 scopus 로고
    • Amino acid profiles correlate diagnostically with organ site in three kinds of malignant tumors
    • [42] Kubota, A., Meguid, M.M., Hitch, D.C., Amino acid profiles correlate diagnostically with organ site in three kinds of malignant tumors. Cancer 69 (1992), 2343–2348 (http://www.scopus.com/inward/record.url?eid=2-s2.0-0026529517&partnerID=tZOtx3y1).
    • (1992) Cancer , vol.69 , pp. 2343-2348
    • Kubota, A.1    Meguid, M.M.2    Hitch, D.C.3
  • 43
    • 0023928169 scopus 로고
    • Preoperative and postoperative levels of plasma protein and amino acid in esophageal and lung cancer patients
    • [43] Naini, A.B., Dickerson, J.W.T., Brown, M.M., Preoperative and postoperative levels of plasma protein and amino acid in esophageal and lung cancer patients. Cancer 62 (1988), 355–360 (http://www.scopus.com/inward/record.url?eid=2-s2.0-0023928169&partnerID=tZOtx3y1).
    • (1988) Cancer , vol.62 , pp. 355-360
    • Naini, A.B.1    Dickerson, J.W.T.2    Brown, M.M.3
  • 44
    • 84867130104 scopus 로고    scopus 로고
    • Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth
    • [44] van den Heuvel, A.P.J., Jing, J., Wooster, R.F., Bachman, K.E., Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth. Cancer Biol. Ther. 13 (2012), 1185–1194, 10.4161/cbt.21348.
    • (2012) Cancer Biol. Ther. , vol.13 , pp. 1185-1194
    • van den Heuvel, A.P.J.1    Jing, J.2    Wooster, R.F.3    Bachman, K.E.4
  • 45
    • 0347790944 scopus 로고
    • Methods in Enzymology
    • Academic Press, New York, USA C·Hirs
    • [45] Blomback, B., Methods in Enzymology. 1967, Academic Press, New York, USA, C·Hirs.
    • (1967)
    • Blomback, B.1
  • 46
    • 65549096661 scopus 로고    scopus 로고
    • De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy
    • [46] Mashima, T., Seimiya, H., Tsuruo, T., De novo fatty-acid synthesis and related pathways as molecular targets for cancer therapy. Br. J. Cancer 100 (2009), 1369–1372, 10.1038/sj.bjc.6605007.
    • (2009) Br. J. Cancer , vol.100 , pp. 1369-1372
    • Mashima, T.1    Seimiya, H.2    Tsuruo, T.3
  • 47
    • 0030879973 scopus 로고    scopus 로고
    • Lactate production by the lungs in acute lung injury
    • [47] De Backer, D., Creteur, J., Zhang, H., Norrenberg, M., Vincent, J.L., Lactate production by the lungs in acute lung injury. Am. J. Respir. Crit. Care Med. 156 (1997), 1099–1104 (http://www.scopus.com/inward/record.url?eid=2-s2.0-0030879973&partnerID=tZOtx3y1).
    • (1997) Am. J. Respir. Crit. Care Med. , vol.156 , pp. 1099-1104
    • De Backer, D.1    Creteur, J.2    Zhang, H.3    Norrenberg, M.4    Vincent, J.L.5
  • 48
    • 84873327998 scopus 로고    scopus 로고
    • Metabolomics reveals altered metabolic pathways in experimental asthma
    • [48] Ho, W.E., Xu, Y.-J., Xu, F., Cheng, C., Peh, H.Y., Tannenbaum, S.R., et al. Metabolomics reveals altered metabolic pathways in experimental asthma. Am. J. Respir. Cell Mol. Biol. 48 (2013), 204–211, 10.1165/rcmb.2012-0246OC.
    • (2013) Am. J. Respir. Cell Mol. Biol. , vol.48 , pp. 204-211
    • Ho, W.E.1    Xu, Y.-J.2    Xu, F.3    Cheng, C.4    Peh, H.Y.5    Tannenbaum, S.R.6
  • 49
    • 84944750031 scopus 로고    scopus 로고
    • Anti-malarial drug artesunate restores metabolic changes in experimental allergic asthma
    • [49] Ho, W.E., Xu, Y.-J., Xu, F., Cheng, C., Peh, H.Y., Huang, S.-M., et al. Anti-malarial drug artesunate restores metabolic changes in experimental allergic asthma. Metabolomics 11 (2014), 380–390, 10.1007/s11306-014-0699-x.
    • (2014) Metabolomics , vol.11 , pp. 380-390
    • Ho, W.E.1    Xu, Y.-J.2    Xu, F.3    Cheng, C.4    Peh, H.Y.5    Huang, S.-M.6
  • 51
    • 0018664862 scopus 로고
    • Adenine nucleotide degradation during energy depletion in human lymphoblasts. Adenosine accumulation and adenylate energy charge correlation
    • [51] Matsumoto, S.S., Raivio, K.O., Seegmiller, J.E., Adenine nucleotide degradation during energy depletion in human lymphoblasts. Adenosine accumulation and adenylate energy charge correlation. J. Biol. Chem. 254 (1979), 8956–8962 (http://www.scopus.com/inward/record.url?eid=2-s2.0-0018664862&partnerID=tZOtx3y1).
    • (1979) J. Biol. Chem. , vol.254 , pp. 8956-8962
    • Matsumoto, S.S.1    Raivio, K.O.2    Seegmiller, J.E.3
  • 52
    • 0020371232 scopus 로고
    • Isolation, characterization, and purification to homogeneity of a rat brain protein (GABA-modulin)
    • [52] Guidotti, A., Konkel, D.R., Ebstein, B., Corda, M.G., Wise, B.C., Krutzsch, H., et al. Isolation, characterization, and purification to homogeneity of a rat brain protein (GABA-modulin). Proc. Natl. Acad. Sci. 79 (1982), 6084–6088, 10.1073/pnas.79.19.6084.
    • (1982) Proc. Natl. Acad. Sci. , vol.79 , pp. 6084-6088
    • Guidotti, A.1    Konkel, D.R.2    Ebstein, B.3    Corda, M.G.4    Wise, B.C.5    Krutzsch, H.6
  • 53
    • 0023148729 scopus 로고
    • A novel acyl-CoA-binding protein from bovine liver. Effect on fatty acid synthesis
    • [53] Mogensen, I.B., Schulenberg, H., Hansen, H.O., Spener, F., Knudsen, J., A novel acyl-CoA-binding protein from bovine liver. Effect on fatty acid synthesis. Biochem. J. 241 (1987), 189–192 (http://www.scopus.com/inward/record.url?eid=2-s2.0-0023148729&partnerID=tZOtx3y1).
    • (1987) Biochem. J. , vol.241 , pp. 189-192
    • Mogensen, I.B.1    Schulenberg, H.2    Hansen, H.O.3    Spener, F.4    Knudsen, J.5
  • 54
    • 0023875877 scopus 로고
    • Isolation and characterization of porcine diazepam-binding inhibitor, a polypeptide not only of cerebral occurrence but also common in intestinal tissues and with effects on regulation of insulin release
    • [54] Chen, Z., Agerberth, B., Gell, K., Andersson, M., Mutt, V., Ostenson, C.-G., et al. Isolation and characterization of porcine diazepam-binding inhibitor, a polypeptide not only of cerebral occurrence but also common in intestinal tissues and with effects on regulation of insulin release. Eur. J. Biochem. 174 (1988), 244–245, 10.1111/j.1432-1033.1988.tb14089.x.
    • (1988) Eur. J. Biochem. , vol.174 , pp. 244-245
    • Chen, Z.1    Agerberth, B.2    Gell, K.3    Andersson, M.4    Mutt, V.5    Ostenson, C.-G.6
  • 55
    • 0028296147 scopus 로고
    • Acyl-CoA-binding protein (ACBP) can mediate intermembrane acyl-CoA transport and donate acyl-CoA for β-oxidation and glycerolipid synthesis
    • [55] Rasmussen, J.T., Faergeman, N.J., Kristiansen, K., Knudsen, J., Acyl-CoA-binding protein (ACBP) can mediate intermembrane acyl-CoA transport and donate acyl-CoA for β-oxidation and glycerolipid synthesis. Biochem. J. 299 (1994), 165–170 (http://www.scopus.com/inward/record.url?eid=2-s2.0-0028296147&partnerID=tZOtx3y1).
    • (1994) Biochem. J. , vol.299 , pp. 165-170
    • Rasmussen, J.T.1    Faergeman, N.J.2    Kristiansen, K.3    Knudsen, J.4
  • 56
    • 33748260777 scopus 로고    scopus 로고
    • Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer
    • [56] Liu, Y., Fatty acid oxidation is a dominant bioenergetic pathway in prostate cancer. Prostate Cancer Prostatic Dis. 9 (2006), 230–234, 10.1038/sj.pcan.4500879.
    • (2006) Prostate Cancer Prostatic Dis. , vol.9 , pp. 230-234
    • Liu, Y.1
  • 58
    • 0020426260 scopus 로고
    • Abnormalities in glucose and protein metabolism in noncachectic lung cancer patients
    • [58] Heber, D., Chlebowski, R.T., Ishibashi, D.E., Herrold, J.N., Block, J.B., Abnormalities in glucose and protein metabolism in noncachectic lung cancer patients. Cancer Res. 42 (1982), 4815–4819 (http://www.scopus.com/inward/record.url?eid=2-s2.0-0020426260&partnerID=tZOtx3y1).
    • (1982) Cancer Res. , vol.42 , pp. 4815-4819
    • Heber, D.1    Chlebowski, R.T.2    Ishibashi, D.E.3    Herrold, J.N.4    Block, J.B.5
  • 59
    • 0028807102 scopus 로고
    • Low plasma cholesterol predicts an increased risk of lung-cancer in elderly women
    • [59] Chang, A.K., Barrettconnor, E., Edelstein, S., Low plasma cholesterol predicts an increased risk of lung-cancer in elderly women. Prev. Med. (Baltimore) 24 (1995), 557–562, 10.1006/pmed.1995.1089.
    • (1995) Prev. Med. (Baltimore) , vol.24 , pp. 557-562
    • Chang, A.K.1    Barrettconnor, E.2    Edelstein, S.3
  • 60
    • 3042562283 scopus 로고    scopus 로고
    • Molecular causes of the aberrant choline phospholipid metabolism in breast cancer
    • [60] Glunde, K., Jie, C., Bhujwalla, Z.M., Molecular causes of the aberrant choline phospholipid metabolism in breast cancer. Cancer Res. 64 (2004), 4270–4276, 10.1158/0008-5472.CAN-03-3829.
    • (2004) Cancer Res. , vol.64 , pp. 4270-4276
    • Glunde, K.1    Jie, C.2    Bhujwalla, Z.M.3
  • 61
    • 84873471978 scopus 로고    scopus 로고
    • Cancer biomarkers and mass spectrometry-based analyses of phospholipids in body fluids
    • [61] Jelonek, K., Ros, M., Pietrowska, M., Widlak, P., Cancer biomarkers and mass spectrometry-based analyses of phospholipids in body fluids. Clin. Lipidol. 8 (2013), 137–150, 10.2217/clp.12.79.
    • (2013) Clin. Lipidol. , vol.8 , pp. 137-150
    • Jelonek, K.1    Ros, M.2    Pietrowska, M.3    Widlak, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.