Variants within the SP110 nuclear body protein modify risk of canine degenerative myelopathy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 22, 2016, Pages E3091-E3100

  Ivansson, Emma L ^a,b,g   Megquier, Kate ^a,b   Kozyrev, Sergey V ^a   Murén, Eva ^a   Körberg, Izabella Baranowska ^c,h   Swofford, Ross ^b   Koltookian, Michele ^b   Tonomura, Noriko ^b,d   Zeng, Rong ^e   Kolicheski, Ana L ^e   Hansen, Liz ^e   Katz, Martin L ^f   Johnson, Gayle C ^e   Johnson, Gary S ^e   Coates, Joan R ^e   Lindblad Toh, Kerstin ^a,b  

^a UPPSALA UNIVERSITY   (Sweden)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^d TUFTS UNIVERSITY   (United States)

^e UNIVERSITY OF MISSOURI   (United States)

^f University of Missouri   (United States)

^g KAROLINSKA INSTITUTE   (Sweden)

^h KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

ALS; Amyotrophic lateral sclerosis; Degenerative myelopathy; SOD1; SP110

Indexed keywords

NUCLEAR PROTEIN; SP110 NUCLEAR BODY PROTEIN; UNCLASSIFIED DRUG; MESSENGER RNA; SUPEROXIDE DISMUTASE;

ALLELE; ALTERNATIVE RNA SPLICING; ARTICLE; BINDING AFFINITY; BREED; CANINE DEGENERATIVE MYELOPATHY; CHROMOSOME; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOG DISEASE; EXON; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPE; NONHUMAN; ONSET AGE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN MODIFICATION; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; SPINAL CORD DISEASE; ANIMAL; DISEASE MODEL; DOG; FEMALE; GENETICS; HOMOZYGOTE; MALE; MUSCLE DISEASE; MUTATION; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGE OF ONSET; ANIMALS; DISEASE MODELS, ANIMAL; DOG DISEASES; DOGS; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HOMOZYGOTE; MALE; MUSCULAR DISEASES; MUTATION; NEURODEGENERATIVE DISEASES; NUCLEAR PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPINAL CORD DISEASES; SUPEROXIDE DISMUTASE;

EID: 84973096924     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1600084113     Document Type: Article

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