Functional Sites Induce Long-Range Evolutionary Constraints in Enzymes

PLoS Biology

Volumn 14, Issue 5, 2016, Pages

  Jack, Benjamin R ^a   Meyer, Austin G ^a   Echave, Julian ^b   Wilke, Claus O ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b UNIVERSIDAD NACIONAL DE SAN MARTÍN   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME; MONOMER; POLYMER; SOLVENT;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME ANALYSIS; MOLECULAR EVOLUTION; PROTEIN DATABASE; PROTEIN PROTEIN INTERACTION; SURFACE AREA; CHEMISTRY; CONSERVED SEQUENCE; METABOLISM; PROTEIN CONFORMATION; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CONSERVED SEQUENCE; DATABASES, PROTEIN; ENZYMES; EVOLUTION, MOLECULAR; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 84971655027     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1002452     Document Type: Article

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