Site-specific structural constraints on protein sequence evolutionary divergence: Local packing density versus solvent exposure

Molecular Biology and Evolution

Volumn 31, Issue 1, 2014, Pages 135-139

  Yeh, So Wei ^a   Liu, Jen Wei ^a   Yu, Sung Huan ^a   Shih, Chien Hua ^a   Hwang, Jenn Kang ^a   Echave, Julian ^b  

^a NATIONAL CHIAO TUNG UNIVERSITY   (Taiwan)

^b UNIVERSIDAD NACIONAL DE SAN MARTÍN   (Argentina)

Author keywords

contact number; local packing density; protein evolution; protein structure; relative solvent accessibility; site specific evolutionary rate; weighted contact number

Indexed keywords

AMINO ACID; ENZYME; PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; COMPARATIVE STUDY; CORRELATIONAL STUDY; EVOLUTIONARY RATE; MOLECULAR EVOLUTION; MUTATION; PROTEIN FUNCTION; PROTEIN STRUCTURE;

CONTACT NUMBER; LOCAL PACKING DENSITY; PROTEIN EVOLUTION; PROTEIN STRUCTURE; RELATIVE SOLVENT ACCESSIBILITY; SITE-SPECIFIC EVOLUTIONARY RATE; WEIGHTED CONTACT NUMBER;

AMINO ACID SUBSTITUTION; ENZYMES; EVOLUTION, MOLECULAR; MUTATION; PROTEIN CONFORMATION; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84891761205     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mst178     Document Type: Article

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