Lactobacillus rhamnosus GG increases Toll-like receptor 3 gene expression in murine small intestine ex vivo and in vivo

Beneficial Microbes

Volumn 7, Issue 3, 2016, Pages 421-429

  Aoki Yoshida, A ^a,b   Saito, S ^b   Fukiya, S ^b   Aoki, R ^c   Takayama, Y ^c   Suzuki, C ^c   Sonoyama, K ^b  

^a UNIVERSITY OF TOKYO   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF LIVESTOCK AND GRASSLAND SCIENCE   (Japan)

Author keywords

CXCL1; Interferon ; Intestinal organoids; Probiotics; Rotavirus

Indexed keywords

ALPHA INTERFERON; CXCL1 CHEMOKINE; MESSENGER RNA; PROBIOTIC AGENT; TOLL LIKE RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BIFIDOBACTERIUM BIFIDUM; CONTROLLED STUDY; CXCL1 GENE; EX VIVO STUDY; FEMALE; GENE EXPRESSION REGULATION; IMMUNOSTIMULATION; IN VIVO STUDY; INNATE IMMUNITY; INTESTINE CRYPT; LACTOBACILLUS PARACASEI; LACTOBACILLUS RHAMNOSUS; MOUSE; NONHUMAN; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SMALL INTESTINE; SUPPLEMENTATION; TLR3 GENE; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; C57BL MOUSE; CYTOPLASM; DISEASE MODEL; GENE EXPRESSION; GENE EXPRESSION PROFILING; IMMUNOLOGY; PATHOLOGY; ROTAVIRUS INFECTIONS;

ANIMALS; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GENE EXPRESSION PROFILING; INTESTINE, SMALL; LACTOBACILLUS RHAMNOSUS; MICE, INBRED C57BL; MODELS, BIOLOGICAL; ORGANOIDS; PROBIOTICS; REAL-TIME POLYMERASE CHAIN REACTION; ROTAVIRUS INFECTIONS; TOLL-LIKE RECEPTOR 3;

EID: 84971612033     PISSN: 18762883     EISSN: 18762891     Source Type: Journal    
DOI: 10.3920/BM2015.0169     Document Type: Article

References (32)

1. Abreu, M.T., Fukata, M. and Arditi, M., 2005. TLR signaling in the gut in health and disease. Journal of Immunology 174: 4453-4460.
2. Alexopoulou, L., Holt, A.C., Medzhitov, R. and Flavell, R.A., 2001. Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3. Nature 413: 732-738.
3. Basu, S., Paul, D.K., Ganguly, S., Chatterjee, M. and Chandra, P.K., 2009. Efficacy of high-dose Lactobacillus rhamnosus GG in controlling acute watery diarrhea in Indian children: a randomized controlled trial. Journal of Clinical Gastroenterology 43: 208-213.
4. Estes, M.K. and Morris, A.P., 1999. A viral enterotoxin. A new mechanism of virus-induced pathogenesis. Advances in Experimental Medicine and Biology 473: 73-82.
5. Feng, N.G., Jaimes, M.C., Lazarus, N.H., Monak, D. and Zhang, C.Q., 2006. Redundant role of chemokines CCL25/TECK and CCL28/MEC in IgA+ plasmablast recruitment to the intestinal lamina propria after RV infection. Journal of Immunology 176: 5749-5759.
6. Finkbeiner, S.R., Zeng, X.L., Utama, B., Atmar, R.L., Shroyer, N.F. and Estes, M.K., 2012. Stem cell-derived human intestinal organoids as an infection model for rotaviruses. mBio 3: e00159-12.
7. Foulke-Abel, J., In, J., Kovbasnjuk, O., Zachos, N.C., Ettayebi, K., Blutt, S.E., Hyser, J.M., Zeng, X.L., Crawford, S.E., Broughman, J.R., Estes, M.K. and Donowitz, M., 2014. Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract. Experimental Biology and Medicine 239: 1124-1134.
8. Guandalini, S., Pensabene, L., Zikri, M.A., Dias, J.A., Casali, L.G., Hoekstra, H., Kolacek, S., Massar, K., Micetic-Turk, D., Papadopoulou, A., De Sousa, J.S., Sandhu, B., Szajewska, H. and Weizman, Z., 2000. Lactobacillus GG administered in oral rehydration solution to children with acute diarrhea: a multicenter European trial. Journal of Pediatric Gastroenterology and Nutrition 30: 54-60.
9. Hill, C., Guarner, F., Reid, G., Gibson, G.R., Merenstein, D.J., Pot, B., Morelli, L., Canani, R.B., Flint, H.J., Salminen, S., Calder, P.C. and Sanders, M.E., 2014. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nature Reviews, Gastroenterology and Hepatology 11: 506-514.
10. Imaizumi, T., Aizawa, T., Segawa, C., Shimada, M., Tsuruga, K., Kawaguchi, S., Matsumiya, T., Yoshida, H., Joh, K. and Tanaka, H., 2014. Toll-like receptor 3 signalling contributes to the expression of a neutrophil chemoattractant, CXCL1 in human mesangial cells. Clinical and Experimental Nephrology 19: 761-770.
11. Isolauri, E., 2004. The role of probiotics in paediatrics. Current Paediatrics 14: 104-109.
12. Kaila, M., Isolauri, E., Saxelin, M., Arvilommi, H. and Vesikari, T., 1995. Viable versus inactivated Lactobacillus strain GG in acute RV diarrhea. Archives of Disease in Childhood 72: 51-53.
13. Kawai, T. and Akira, S., 2006. TLR signaling. Cell Death and Differentiation 13: 816-825.
14. Kovbasnjuk, O., Zachos, N.C., In, J., Foulke-Abel, J., Ettayebi, K., Hyser, J.M., Broughman, J.R., Zeng, X.L., Middendorp, S., De Jonge, H.R., Estes, M.K. and Donowitz, M., 2013. Human enteroids: preclinical models of non-inflammatory diarrhoea. Stem Cell Research and Therapy 4 Suppl. 1: S3.
15. Liévin-Le Moal, V. and Servin, A.L., 2014. Anti-infective activities of Lactobacillus strains in the human intestinal microbiota: from probiotics to gastrointestinal anti- infectious biotherapeutic agents. Clinical Microbiology Reviews 27: 167-199.
16. Liu, F., Li, G., Wen, K., Bui, T., Cao, D., Zhang, Y. and Yuan, L., 2010. Porcine small intestinal epithelial cell line (IPEC-J2) of rotavirus infection as a new model for the study of innate immune responses to rotaviruses and probiotics. Viral Immunology 23: 135-149.
17. Majamaa, H., Isolauri, E., Saxelin, M. and Vesikari, T., 1995. Lactic acid bacteria in the treatment of acute rotavirus gastroenteritis. Journal of Pediatric Gastroenterology and Nutrition 20: 333-338.
18. Maragkoudakis, P.A., Chingwaru, W., Gradisnik, L., Tsakalidou, E. and Cencic, A., 2010. Lactic acid bacteria efficiently protect human and animal intestinal epithelial and immune cells from enteric virus infection. International Journal of Food Microbiology 141 Suppl. 1: S91-S97.
19. Matsumoto, M. and Seya, T., 2008. TLR3: interferon induction by double-stranded RNA including poly(I:C). Advanced Drug Delivery Reviews 60: 805-812.
20. Pant, A.R., Graham, S.M., Allen, S.J., Harikul, S., Sabchareon, A., Cuevas, L. and Hart, C.A., 1996. Lactobacillus GG and acute diarrhoea in young children in the tropics. Journal of Tropical Pediatrics 42: 162-165.
21. Pott, J., Stockinger, S., Torow, N., Smoczek, A., Lindner, C., McInerney, G., Bäckhed, F., Baumann, U., Pabst, O., Bleich, A. and Hornef, M.W., 2012. Age-dependent TLR3 expression of the intestinal epithelium contributes to rotavirus susceptibility. PLoS Pathogens 8: e1002670.
22. Rautanen, T., Isolauri, E., Salo, E. and Vesikari, T., 1998. Management of acute diarrhoea with low osmolarity oral rehydration solutions and Lactobacillus strain GG. Archives of Disease in Childhood 79: 157-160.
23. Saavedra, J.M., Bauman, N.A., Oung, I., Perman, J.A. and Yolken, R.H., 1994. Feeding of Bifidobacterium bifidum and Streptococcus thermophilus to infants in hospital for prevention of diarrhoea and shedding of rotavirus. The Lancet 344: 1046-1049.
24. Sarker, S.A., Sultana, S., Fuchs, G.J., Alam, N.H., Azim, T., Brüssow, H. and Hammarström, L., 2005. Lactobacillus paracasei strain ST11 has no effect on rotavirus but ameliorates the outcome of nonrotavirus diarrhea in children from Bangladesh. Pediatrics 116: e221-e228.
25. Sato, A., Iizuka, M., Nakagomi, O., Suzuki, M., Horie, Y., Konno, S., Hirasawa, F., Sasaki, K., Shindo, K. and Watanabe, S., 2006. Rotavirus double-stranded RNA induces apoptosis and diminishes wound repair in rat intestinal epithelial cells. Journal of Gastroenterology and Hepatology 21: 521-530.
26. Sato, T., Vries, R.G., Snippert, H.J., Van de Wetering, M., Barker, N., Stange, D.E., Van Es, J.H., Abo, A., Kujala, P., Peters, P.J. and Clevers, H., 2009. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459: 262-265.
27. Sugata, K., Taniguchi, K., Yui, A., Miyake, F. and Suqa, S., 2008. Analysis of rotavirus antigenemia and extra-intestinal manifestation in children with rotavirus gastroenteritis. Pediatrics 122: 329-397.
28. Wen, K., Tin, C., Wang, H., Yang, X., Li, G., Giri-Rachman, E., Kocher, J., Bui, T., Clark-Deener, S. and Yuan, L., 2014. Probiotic Lactobacillus rhamnosus GG enhanced Th1 cellular immunity but did not affect antibody responses in a human gut microbiota transplanted neonatal gnotobiotic pig model. PLoS One 9: e94504.
29. Wilson, S.S., Tocchi, A., Holly, M.K., Parks, W.C. and Smith, J.G., 2015. A small intestinal organoid model of non-invasive enteric pathogenepithelial cell interactions. Mucosal Immunology 8: 352-361.
30. Yin, Y., Bijvelds, M., Dang, W., Xu, L., Van der Eijk, A.A., Knipping, K., Tuysuz, N., Dekkers, J.F., Wang, Y., De Jonge, J., Sprengers, D., Van der Laan, L.J., Beekman, J.M., Ten Berge, D., Metselaar, H.J., De Jonge, H., Koopmans, M.P., Peppelenbosch, M.P. and Pan, Q., 2015. Modeling rotavirus infection and antiviral therapy using primary intestinal organoids. Antiviral Research 123: 120-131.
31. Yu, S. and Gao, N., 2015. Compartmentalizing intestinal epithelial cell toll-like receptors for immune surveillance. Cellular and Molecular Life Sciences 72: 3343-3353.
32. Zhou, R., Wei, H., Sun, R. and Tian, Z., 2007. Recognition of doublestranded RNA by TLR3 induces severe small intestinal injury in mice. Journal of Immunology 178: 4548-4556.