Two C4-sterol methyl oxidases (Erg25) catalyse ergosterol intermediate demethylation and impact environmental stress adaptation in Aspergillus fumigatus

Microbiology (United Kingdom)

Volumn 160, Issue , 2014, Pages 2492-2506

  Blosser, Sara J ^a   Merriman, Brittney ^a   Grahl, Nora ^a,b   Chung, Dawoon ^a,b   Cramer, Robert A ^a,b  

^a MONTANA STATE UNIVERSITY   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; C4 DEMETHYLASE; C4 METHYL STEROL; C4 STEROL METHYL OXIDASE; CORTICOSTEROID; ERGOSTEROL; FLUCONAZOLE; FUNGAL ENZYME; STEROL; UNCLASSIFIED DRUG; VORICONAZOLE; FUNGAL PROTEIN; METHYLSTEROL MONOOXYGENASE; MIXED FUNCTION OXIDASE;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIFUNGAL SUSCEPTIBILITY; ARTICLE; ASPERGILLUS FUMIGATUS; BIOSYNTHESIS; CONTROLLED STUDY; DEMETHYLATION; ENDOPLASMIC RETICULUM STRESS; ENVIRONMENTAL STRESS; ESSENTIAL GENE; FEMALE; FUNGAL GENE; FUNGAL VIRULENCE; FUNGUS GROWTH; FUNGUS MUTATION; GALLERIA MELLONELLA; GENE DELETION; HYPOXIA; INVASIVE ASPERGILLOSIS; LUNG ASPERGILLOSIS; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; STEROL SYNTHESIS; ASPERGILLOSIS; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; METHYLATION; MICROBIOLOGY; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; ERGOSTEROL; FUNGAL PROTEINS; HUMANS; METHYLATION; MIXED FUNCTION OXYGENASES;

EID: 84964313028     PISSN: 13500872     EISSN: 14652080     Source Type: Journal    
DOI: 10.1099/mic.0.080440-0     Document Type: Article

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