메뉴 건너뛰기




Volumn 84, Issue 6, 2016, Pages 1743-1752

Borrelia burgdorferi CheD promotes various functions in chemotaxis and the pathogenic life cycle of the spirochete

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; METHYL ACCEPTING CHEMOTAXIS PROTEIN; PHOSPHATASE; PROTEIN CHEX; UNCLASSIFIED DRUG; CHED PROTEIN, BACILLUS SUBTILIS; ISOPROTEIN; RECOMBINANT PROTEIN;

EID: 84971524653     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01347-15     Document Type: Article
Times cited : (22)

References (68)
  • 1
    • 22944444886 scopus 로고    scopus 로고
    • Going against the grain: Chemotaxis and infection in Vibrio cholerae
    • Butler SM, Camilli A. 2005. Going against the grain: chemotaxis and infection in Vibrio cholerae. Nat Rev Microbiol 3: 611-620. http://dx.doi.org/10.1038/nrmicro1207.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 611-620
    • Butler, S.M.1    Camilli, A.2
  • 2
    • 80053238890 scopus 로고    scopus 로고
    • Motility and chemotaxis in Campylobacter and Helicobacter
    • Lertsethtakarn P, Ottemann KM, Hendrixson DR. 2011. Motility and chemotaxis in Campylobacter and Helicobacter. Annu Rev Microbiol 65: 389-410. http://dx.doi.org/10.1146/annurev-micro-090110-102908.
    • (2011) Annu Rev Microbiol , vol.65 , pp. 389-410
    • Lertsethtakarn, P.1    Ottemann, K.M.2    Hendrixson, D.R.3
  • 3
    • 84923271143 scopus 로고    scopus 로고
    • The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi
    • Novak EA, Sultan SZ, Motaleb MA. 2014. The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, Borrelia burgdorferi. Front Cell Infect Microbiol 4: 56. http://dx.doi.org/10.3389/fcimb.2014.00056.
    • (2014) Front Cell Infect Microbiol , vol.4 , pp. 56
    • Novak, E.A.1    Sultan, S.Z.2    Motaleb, M.A.3
  • 6
    • 84945949541 scopus 로고    scopus 로고
    • Spirochetal motility and chemotaxis in the natural enzootic cycle and development of Lyme disease
    • Motaleb M, Liu J, Wooten RM. 2015. Spirochetal motility and chemotaxis in the natural enzootic cycle and development of Lyme disease. Curr Opin Microbiol 28: 106-113. http://dx.doi.org/10.1016/j.mib.2015.09.006.
    • (2015) Curr Opin Microbiol , vol.28 , pp. 106-113
    • Motaleb, M.1    Liu, J.2    Wooten, R.M.3
  • 7
    • 84864821396 scopus 로고    scopus 로고
    • Borrelia burgdorferi needs chemotaxis to establish infection in mammals and to accomplish its enzootic cycle
    • Sze CW, Zhang K, Kariu T, Pal U, Li C. 2012. Borrelia burgdorferi needs chemotaxis to establish infection in mammals and to accomplish its enzootic cycle. Infect Immun 80: 2485-2492. http://dx.doi.org/10.1128/IAI.00145-12.
    • (2012) Infect Immun , vol.80 , pp. 2485-2492
    • Sze, C.W.1    Zhang, K.2    Kariu, T.3    Pal, U.4    Li, C.5
  • 9
    • 84928184720 scopus 로고    scopus 로고
    • Motor rotation is essential for the formation of the periplasmic flagellar ribbon, cellular morphology, and Borrelia burgdorferi persistence within Ixodes scapularis tick and murine hosts
    • Sultan SZ, Sekar P, Zhao X, Manne A, Liu J, Wooten RM, Motaleb MA. 2015. Motor rotation is essential for the formation of the periplasmic flagellar ribbon, cellular morphology, and Borrelia burgdorferi persistence within Ixodes scapularis tick and murine hosts. Infect Immun 83: 1765-1777. http://dx.doi.org/10.1128/IAI.03097-14.
    • (2015) Infect Immun , vol.83 , pp. 1765-1777
    • Sultan, S.Z.1    Sekar, P.2    Zhao, X.3    Manne, A.4    Liu, J.5    Wooten, R.M.6    Motaleb, M.A.7
  • 10
    • 77949392836 scopus 로고    scopus 로고
    • Inactivation of a putative flagellar motor switch protein FliG1 prevents Borrelia burgdorferi from swimming in highly viscous media and blocks its infectivity
    • Li C, Xu H, Zhang K, Liang FT. 2010. Inactivation of a putative flagellar motor switch protein FliG1 prevents Borrelia burgdorferi from swimming in highly viscous media and blocks its infectivity. Mol Microbiol 75: 1563-1576. http://dx.doi.org/10.1111/j.1365-2958.2010.07078.x.
    • (2010) Mol Microbiol , vol.75 , pp. 1563-1576
    • Li, C.1    Xu, H.2    Zhang, K.3    Liang, F.T.4
  • 11
    • 85047688053 scopus 로고    scopus 로고
    • FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath
    • Lambert A, Picardeau M, Haake DA, Sermswan RW, Srikram A, Adler B, Murray GA. 2012. FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath. Infect Immun 80: 2019-2025. http://dx.doi.org/10.1128/IAI.00131-12.
    • (2012) Infect Immun , vol.80 , pp. 2019-2025
    • Lambert, A.1    Picardeau, M.2    Haake, D.A.3    Sermswan, R.W.4    Srikram, A.5    Adler, B.6    Murray, G.A.7
  • 12
    • 84883245007 scopus 로고    scopus 로고
    • Periplasmic flagellar export apparatus protein, FliH, is involved in post-transcriptional regulation of FlaB, motility and virulence of the relapsing fever spirochete Borrelia hermsii
    • Guyard C, Raffel SJ, Schrumpf ME, Dahlstrom E, Sturdevant D, Ricklefs SM, Martens C, Hayes SF, Fischer ER, Hansen BT. 2013. Periplasmic flagellar export apparatus protein, FliH, is involved in post-transcriptional regulation of FlaB, motility and virulence of the relapsing fever spirochete Borrelia hermsii. PLoS One 8: e72550. http://dx.doi.org/10.1371/journal.pone.0072550.
    • (2013) PLoS One , vol.8 , pp. e72550
    • Guyard, C.1    Raffel, S.J.2    Schrumpf, M.E.3    Dahlstrom, E.4    Sturdevant, D.5    Ricklefs, S.M.6    Martens, C.7    Hayes, S.F.8    Fischer, E.R.9    Hansen, B.T.10
  • 13
    • 84936935603 scopus 로고    scopus 로고
    • Mutations in the Borrelia burgdorferi flagellar type III secretion system genes fliH and fliI pro-foundly affect spirochete flagellar assembly, morphology, motility, structure, and cell division
    • Lin T, Gao L, Zhao X, Liu J, Norris SJ. 2015. Mutations in the Borrelia burgdorferi flagellar type III secretion system genes fliH and fliI pro-foundly affect spirochete flagellar assembly, morphology, motility, structure, and cell division. mBio 6: e00579-15. http://dx.doi.org/10.1128/mBio.00579-15.
    • (2015) mBio , vol.6 , pp. e00579-e00615
    • Lin, T.1    Gao, L.2    Zhao, X.3    Liu, J.4    Norris, S.J.5
  • 16
    • 0015966184 scopus 로고
    • Effect of viscosity on bacterial motility
    • Schneider WR, Doetsch RN. 1974. Effect of viscosity on bacterial motility. J Bacteriol 117: 696-701.
    • (1974) J Bacteriol , vol.117 , pp. 696-701
    • Schneider, W.R.1    Doetsch, R.N.2
  • 17
    • 0005673441 scopus 로고
    • The measurement of bacterial motility
    • Shoesmith J. 1960. The measurement of bacterial motility. J Gen Microbiol 22: 528-535. http://dx.doi.org/10.1099/00221287-22-2-528.
    • (1960) J Gen Microbiol , vol.22 , pp. 528-535
    • Shoesmith, J.1
  • 18
    • 0023835736 scopus 로고
    • Motility of the spirochete Leptospira
    • Goldstein SF, Charon NW. 1988. Motility of the spirochete Leptospira. Cell Motil Cytoskeleton 9: 101-110. http://dx.doi.org/10.1002/cm.970090202.
    • (1988) Cell Motil Cytoskeleton , vol.9 , pp. 101-110
    • Goldstein, S.F.1    Charon, N.W.2
  • 19
    • 0027651128 scopus 로고
    • Viscosity-dependent locomotion of oral spirochetes
    • Klitorinos A, Noble P, Siboo R, Chan E. 1993. Viscosity-dependent locomotion of oral spirochetes. Oral Microbiol Immunol 8: 242-244. http://dx.doi.org/10.1111/j.1399-302X.1993.tb00567.x.
    • (1993) Oral Microbiol Immunol , vol.8 , pp. 242-244
    • Klitorinos, A.1    Noble, P.2    Siboo, R.3    Chan, E.4
  • 20
    • 33646170854 scopus 로고    scopus 로고
    • Improvement in motion efficiency of the spirochete Brachyspira pilosicoli in viscous environments
    • Nakamura S, Adachi Y, Goto T, Magariyama Y. 2006. Improvement in motion efficiency of the spirochete Brachyspira pilosicoli in viscous environments. Biophys J 90: 3019-3026. http://dx.doi.org/10.1529/biophysj.105.074336.
    • (2006) Biophys J , vol.90 , pp. 3019-3026
    • Nakamura, S.1    Adachi, Y.2    Goto, T.3    Magariyama, Y.4
  • 21
    • 84907381226 scopus 로고    scopus 로고
    • Review: Unraveling Lyme disease
    • Bockenstedt LK, Wormser GP. 2014. Review: unraveling Lyme disease. Arthritis Rheumatol 66: 2313-2323. http://dx.doi.org/10.1002/art.38756.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 2313-2323
    • Bockenstedt, L.K.1    Wormser, G.P.2
  • 22
    • 84951325747 scopus 로고    scopus 로고
    • Bacterial chemotaxis: Information processing, thermodynamics, and behavior
    • Micali G, Endres RG. 2016. Bacterial chemotaxis: information processing, thermodynamics, and behavior. Curr Opin Microbiol 30: 8-15. http://dx.doi.org/10.1016/j.mib.2015.12.001.
    • (2016) Curr Opin Microbiol , vol.30 , pp. 8-15
    • Micali, G.1    Endres, R.G.2
  • 23
    • 84861836686 scopus 로고    scopus 로고
    • Responding to chemical gradients: Bacterial chemotaxis
    • Sourjik V, Wingreen NS. 2012. Responding to chemical gradients: bacterial chemotaxis. Curr Opin Cell Biol 24: 262-268. http://dx.doi.org/10.1016/j.ceb.2011.11.008.
    • (2012) Curr Opin Cell Biol , vol.24 , pp. 262-268
    • Sourjik, V.1    Wingreen, N.S.2
  • 24
    • 84925492168 scopus 로고    scopus 로고
    • Bacterial chemoreceptors and chemoeffectors
    • Bi S, Lai L. 2015. Bacterial chemoreceptors and chemoeffectors. Cell Mol Life Sci 72: 691-708. http://dx.doi.org/10.1007/s00018-014-1770-5.
    • (2015) Cell Mol Life Sci , vol.72 , pp. 691-708
    • Bi, S.1    Lai, L.2
  • 25
    • 77952679686 scopus 로고    scopus 로고
    • Chemotaxis signaling protein CheY binds to the rotor protein FliN to control the direction of flagellar rotation in Escherichia coli
    • Sarkar MK, Paul K, Blair D. 2010. Chemotaxis signaling protein CheY binds to the rotor protein FliN to control the direction of flagellar rotation in Escherichia coli. Proc Natl Acad SciUSA 107: 9370-9375. http://dx.doi.org/10.1073/pnas.1000935107.
    • (2010) Proc Natl Acad SciUSA , vol.107 , pp. 9370-9375
    • Sarkar, M.K.1    Paul, K.2    Blair, D.3
  • 26
    • 0033049757 scopus 로고    scopus 로고
    • Throwing the switch in bacterial chemotaxis
    • Silversmith RE, Bourret RB. 1999. Throwing the switch in bacterial chemotaxis. Trends Microbiol 7: 16-22. http://dx.doi.org/10.1016/S0966-842X(98)01409-7.
    • (1999) Trends Microbiol , vol.7 , pp. 16-22
    • Silversmith, R.E.1    Bourret, R.B.2
  • 27
    • 0037067781 scopus 로고    scopus 로고
    • Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis
    • Kristich CJ, Ordal GW. 2002. Bacillus subtilis CheD is a chemoreceptor modification enzyme required for chemotaxis. J Biol Chem 277:25356-25362. http://dx.doi.org/10.1074/jbc.M201334200.
    • (2002) J Biol Chem , vol.277 , pp. 25356-25362
    • Kristich, C.J.1    Ordal, G.W.2
  • 28
    • 84870718488 scopus 로고    scopus 로고
    • The importance of the interaction of CheD with CheC and the chemoreceptors compared to its enzymatic activity during chemotaxis in Bacillus subtilis
    • Yuan W, Glekas GD, Allen GM, Walukiewicz HE, Rao CV, Ordal GW. 2012. The importance of the interaction of CheD with CheC and the chemoreceptors compared to its enzymatic activity during chemotaxis in Bacillus subtilis. PLoS One 7: e50689. http://dx.doi.org/10.1371/journal.pone.0050689.
    • (2012) PLoS One , vol.7 , pp. e50689
    • Yuan, W.1    Glekas, G.D.2    Allen, G.M.3    Walukiewicz, H.E.4    Rao, C.V.5    Ordal, G.W.6
  • 29
    • 32044444785 scopus 로고    scopus 로고
    • A receptor-modifying deamidase in complex with a signaling phosphatase reveals reciprocal regulation
    • Chao X, Muff TJ, Park S, Zhang S, Pollard AM, Ordal GW, Bilwes AM, Crane BR. 2006. A receptor-modifying deamidase in complex with a signaling phosphatase reveals reciprocal regulation. Cell 124: 561-571. http://dx.doi.org/10.1016/j.cell.2005.11.046.
    • (2006) Cell , vol.124 , pp. 561-571
    • Chao, X.1    Muff, T.J.2    Park, S.3    Zhang, S.4    Pollard, A.M.5    Ordal, G.W.6    Bilwes, A.M.7    Crane, B.R.8
  • 30
    • 53049108740 scopus 로고    scopus 로고
    • The three adaptation systems of Bacillus subtilis chemotaxis
    • Rao CV, Glekas GD, Ordal GW. 2008. The three adaptation systems of Bacillus subtilis chemotaxis. Trends Microbiol 16: 480-487. http://dx.doi.org/10.1016/j.tim.2008.07.003.
    • (2008) Trends Microbiol , vol.16 , pp. 480-487
    • Rao, C.V.1    Glekas, G.D.2    Ordal, G.W.3
  • 32
    • 34447107130 scopus 로고    scopus 로고
    • Phosphorylation assays of chemotaxis two-component system proteins in Borrelia burgdor-feri
    • Motaleb MA, Miller MR, Li C, Charon NW. 2007. Phosphorylation assays of chemotaxis two-component system proteins in Borrelia burgdor-feri. Methods Enzymol 422: 438-447. http://dx.doi.org/10.1016/S0076-6879(06)22022-6.
    • (2007) Methods Enzymol , vol.422 , pp. 438-447
    • Motaleb, M.A.1    Miller, M.R.2    Li, C.3    Charon, N.W.4
  • 34
    • 76649097688 scopus 로고    scopus 로고
    • Identical phosphatase mechanisms achieved through distinct modes of binding phosphoprotein substrate
    • Pazy Y, Motaleb MA, Guarnieri MT, Charon NW, Zhao R, Silversmith RE. 2010. Identical phosphatase mechanisms achieved through distinct modes of binding phosphoprotein substrate. Proc Natl Acad Sci U S A 107: 1924-1929. http://dx.doi.org/10.1073/pnas.0911185107.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 1924-1929
    • Pazy, Y.1    Motaleb, M.A.2    Guarnieri, M.T.3    Charon, N.W.4    Zhao, R.5    Silversmith, R.E.6
  • 35
    • 79955642814 scopus 로고    scopus 로고
    • Analysis of the Borrelia burgdorferi cyclic-di-GMP-binding protein PlzA reveals a role in motility and virulence
    • Pitzer JE, Sultan SZ, Hayakawa Y, Hobbs G, Miller MR, Motaleb MA. 2011. Analysis of the Borrelia burgdorferi cyclic-di-GMP-binding protein PlzA reveals a role in motility and virulence. Infect Immun 79: 1815-1825. http://dx.doi.org/10.1128/IAI.00075-11.
    • (2011) Infect Immun , vol.79 , pp. 1815-1825
    • Pitzer, J.E.1    Sultan, S.Z.2    Hayakawa, Y.3    Hobbs, G.4    Miller, M.R.5    Motaleb, M.A.6
  • 36
    • 0034002143 scopus 로고    scopus 로고
    • Efficient targeted mutagenesis in Borrelia burgdorferi
    • Bono JL, Elias AF, Kupko JJ III, Stevenson B, Tilly K, Rosa P. 2000. Efficient targeted mutagenesis in Borrelia burgdorferi. J Bacteriol 182: 2445-2452. http://dx.doi.org/10.1128/JB.182.9.2445-2452.2000.
    • (2000) J Bacteriol , vol.182 , pp. 2445-2452
    • Bono, J.L.1    Elias, A.F.2    Kupko, J.J.3    Stevenson, B.4    Tilly, K.5    Rosa, P.6
  • 39
    • 0033975239 scopus 로고    scopus 로고
    • A bacterial genome in flux: The twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burg-dorferi
    • Casjens S, Palmer N, Van Vugt R, Mun Huang W, Stevenson B, Rosa P, Lathigra R, Sutton G, Peterson J, Dodson RJ. 2000. A bacterial genome in flux: the twelve linear and nine circular extrachromosomal DNAs in an infectious isolate of the Lyme disease spirochete Borrelia burg-dorferi. Mol Microbiol 35: 490-516.
    • (2000) Mol Microbiol , vol.35 , pp. 490-516
    • Casjens, S.1    Palmer, N.2    Van Vugt, R.3    Mun Huang, W.4    Stevenson, B.5    Rosa, P.6    Lathigra, R.7    Sutton, G.8    Peterson, J.9    Dodson, R.J.10
  • 40
    • 70350440467 scopus 로고    scopus 로고
    • GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle
    • Jewett MW, Lawrence KA, Bestor A, Byram R, Gherardini F, Rosa PA. 2009. GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle. J Bacteriol 191: 6231-6241. http://dx.doi.org/10.1128/JB.00450-09.
    • (2009) J Bacteriol , vol.191 , pp. 6231-6241
    • Jewett, M.W.1    Lawrence, K.A.2    Bestor, A.3    Byram, R.4    Gherardini, F.5    Rosa, P.A.6
  • 41
    • 85058203355 scopus 로고    scopus 로고
    • Isolation and characterization of chemotaxis mutants of the Lyme disease spirochete Borrelia burgdorferi using allelic exchange mutagenesis, flow cytometry, and cell tracking
    • Motaleb MA, Miller MR, Bakker RG, Li C, Charon NW. 2007. Isolation and characterization of chemotaxis mutants of the Lyme disease spirochete Borrelia burgdorferi using allelic exchange mutagenesis, flow cytometry, and cell tracking. Methods Enzymol 422: 421-437. http://dx.doi.org/10.1016/S0076-6879(06)22021-4.
    • (2007) Methods Enzymol , vol.422 , pp. 421-437
    • Motaleb, M.A.1    Miller, M.R.2    Bakker, R.G.3    Li, C.4    Charon, N.W.5
  • 42
    • 40549124649 scopus 로고    scopus 로고
    • Transposon mutagenesis of the Lyme disease agent Borrelia burgdorferi
    • Stewart PE, Rosa PA. 2008. Transposon mutagenesis of the Lyme disease agent Borrelia burgdorferi. Methods Mol Biol 431: 85-95.
    • (2008) Methods Mol Biol , vol.431 , pp. 85-95
    • Stewart, P.E.1    Rosa, P.A.2
  • 45
    • 77953988576 scopus 로고    scopus 로고
    • Analysis of a Borrelia burgdorferi phosphodiesterase demonstrates a role for cyclic-diguanosine monophosphate in motility and virulence
    • Sultan SZ, Pitzer JE, Miller MR, Motaleb MA. 2010. Analysis of a Borrelia burgdorferi phosphodiesterase demonstrates a role for cyclic-diguanosine monophosphate in motility and virulence. Mol Microbiol 77: 128-142. http://dx.doi.org/10.1111/j.1365-2958.2010.07191.x.
    • (2010) Mol Microbiol , vol.77 , pp. 128-142
    • Sultan, S.Z.1    Pitzer, J.E.2    Miller, M.R.3    Motaleb, M.A.4
  • 46
    • 70349428512 scopus 로고    scopus 로고
    • BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle
    • Zhang X, Yang X, Kumar M, Pal U. 2009. BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle. J Infect Dis 200: 1318-1330. http://dx.doi.org/10.1086/605846.
    • (2009) J Infect Dis , vol.200 , pp. 1318-1330
    • Zhang, X.1    Yang, X.2    Kumar, M.3    Pal, U.4
  • 48
    • 2942605826 scopus 로고    scopus 로고
    • The decrease in FlaA observed in a flaB mutant of Borrelia burgdorferi occurs posttranscriptionally
    • Motaleb MA, Sal MS, Charon NW. 2004. The decrease in FlaA observed in a flaB mutant of Borrelia burgdorferi occurs posttranscriptionally. J Bacteriol 186: 3703-3711. http://dx.doi.org/10.1128/JB.186.12.3703-3711.2004.
    • (2004) J Bacteriol , vol.186 , pp. 3703-3711
    • Motaleb, M.A.1    Sal, M.S.2    Charon, N.W.3
  • 49
    • 79961113805 scopus 로고    scopus 로고
    • Analysis of the HD-GYP domain cyclic dimeric GMP phosphodiesterase reveals a role in motility and the enzootic life cycle of Borrelia burg-dorferi
    • Sultan SZ, Pitzer JE, Boquoi T, Hobbs G, Miller MR, Motaleb MA. 2011. Analysis of the HD-GYP domain cyclic dimeric GMP phosphodiesterase reveals a role in motility and the enzootic life cycle of Borrelia burg-dorferi. Infect Immun 79: 3273-3283. http://dx.doi.org/10.1128/IAI.05153-11.
    • (2011) Infect Immun , vol.79 , pp. 3273-3283
    • Sultan, S.Z.1    Pitzer, J.E.2    Boquoi, T.3    Hobbs, G.4    Miller, M.R.5    Motaleb, M.A.6
  • 50
    • 67549109657 scopus 로고    scopus 로고
    • A role for the EAL-like protein STM1344 in regulation of CsgD expression and motility in Salmonella enterica serovar Typhimurium
    • Simm R, Remminghorst U, Ahmad I, Zakikhany K, Romling U. 2009. A role for the EAL-like protein STM1344 in regulation of CsgD expression and motility in Salmonella enterica serovar Typhimurium. J Bacteriol 191: 3928-3937. http://dx.doi.org/10.1128/JB.00290-09.
    • (2009) J Bacteriol , vol.191 , pp. 3928-3937
    • Simm, R.1    Remminghorst, U.2    Ahmad, I.3    Zakikhany, K.4    Romling, U.5
  • 51
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2-flflCT method
    • Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-flflCT method. Methods 25: 402-408. http://dx.doi.org/10.1006/meth.2001.1262.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 52
    • 0142183479 scopus 로고    scopus 로고
    • Investigation of the role of electrostatic charge in activation of the Escherichia coli response regulator CheY
    • Smith JG, Latiolais JA, Guanga GP, Citineni S, Silversmith RE, Bourret RB. 2003. Investigation of the role of electrostatic charge in activation of the Escherichia coli response regulator CheY. J Bacteriol 185: 6385-6391. http://dx.doi.org/10.1128/JB.185.21.6385-6391.2003.
    • (2003) J Bacteriol , vol.185 , pp. 6385-6391
    • Smith, J.G.1    Latiolais, J.A.2    Guanga, G.P.3    Citineni, S.4    Silversmith, R.E.5    Bourret, R.B.6
  • 53
    • 79959326874 scopus 로고    scopus 로고
    • CheY3 of Borrelia burgdorferi is the key response regulator essential for chemotaxis and forms a long-lived phosphorylated intermediate
    • Motaleb MA, Sultan SZ, Miller MR, Li C, Charon NW. 2011. CheY3 of Borrelia burgdorferi is the key response regulator essential for chemotaxis and forms a long-lived phosphorylated intermediate. J Bacteriol 193: 3332-3341. http://dx.doi.org/10.1128/JB.00362-11.
    • (2011) J Bacteriol , vol.193 , pp. 3332-3341
    • Motaleb, M.A.1    Sultan, S.Z.2    Miller, M.R.3    Li, C.4    Charon, N.W.5
  • 54
    • 0031592943 scopus 로고    scopus 로고
    • Distinct regions of bacterial flagellar switch protein FliM interact with FliG, FliN and CheY
    • Toker AS, Macnab RM. 1997. Distinct regions of bacterial flagellar switch protein FliM interact with FliG, FliN and CheY. J Mol Biol 273: 623-634. http://dx.doi.org/10.1006/jmbi.1997.1335.
    • (1997) J Mol Biol , vol.273 , pp. 623-634
    • Toker, A.S.1    Macnab, R.M.2
  • 55
    • 0030817793 scopus 로고    scopus 로고
    • Catalytic mechanism of phosphorylation and dephosphorylation of CheY: Kinetic characterization of imidazole phosphates as phosphodonors and the role of acid catalysis
    • Silversmith RE, Appleby JL, Bourret RB. 1997. Catalytic mechanism of phosphorylation and dephosphorylation of CheY: kinetic characterization of imidazole phosphates as phosphodonors and the role of acid catalysis. Biochemistry 36: 14965-14974. http://dx.doi.org/10.1021/bi9715573.
    • (1997) Biochemistry , vol.36 , pp. 14965-14974
    • Silversmith, R.E.1    Appleby, J.L.2    Bourret, R.B.3
  • 56
    • 13444293534 scopus 로고    scopus 로고
    • The burgeoning molecular genetics of the Lyme disease spirochaete
    • Rosa PA, Tilly K, Stewart PE. 2005. The burgeoning molecular genetics of the Lyme disease spirochaete. Nat Rev Microbiol 3: 129-143. http://dx.doi.org/10.1038/nrmicro1086.
    • (2005) Nat Rev Microbiol , vol.3 , pp. 129-143
    • Rosa, P.A.1    Tilly, K.2    Stewart, P.E.3
  • 57
    • 79959326635 scopus 로고    scopus 로고
    • A novel gene inactivation system reveals altered periplasmic flagellar orientation in a Borrelia burg-dorferi fliL mutant
    • Motaleb MA, Pitzer JE, Sultan SZ, Liu J. 2011. A novel gene inactivation system reveals altered periplasmic flagellar orientation in a Borrelia burg-dorferi fliL mutant. J Bacteriol 193: 3324-3331. http://dx.doi.org/10.1128/JB.00202-11.
    • (2011) J Bacteriol , vol.193 , pp. 3324-3331
    • Motaleb, M.A.1    Pitzer, J.E.2    Sultan, S.Z.3    Liu, J.4
  • 58
    • 42949083309 scopus 로고    scopus 로고
    • A tightly regulated surface protein of Borrelia burgdorferi is not essential to the mouse-tick infectious cycle
    • Stewart PE, Bestor A, Cullen JN, Rosa PA. 2008. A tightly regulated surface protein of Borrelia burgdorferi is not essential to the mouse-tick infectious cycle. Infect Immun 76: 1970-1978. http://dx.doi.org/10.1128/IAI.00714-07.
    • (2008) Infect Immun , vol.76 , pp. 1970-1978
    • Stewart, P.E.1    Bestor, A.2    Cullen, J.N.3    Rosa, P.A.4
  • 60
    • 0025977648 scopus 로고
    • Antibody to a 39-kilodalton Borrelia burgdorferi antigen (P39) as a marker for infection in experimentally and naturally inoculated animals
    • Simpson WJ, Burgdorfer W, Schrumpf ME, Karstens RH, Schwan TG. 1991. Antibody to a 39-kilodalton Borrelia burgdorferi antigen (P39) as a marker for infection in experimentally and naturally inoculated animals. J Clin Microbiol 29: 236-243.
    • (1991) J Clin Microbiol , vol.29 , pp. 236-243
    • Simpson, W.J.1    Burgdorfer, W.2    Schrumpf, M.E.3    Karstens, R.H.4    Schwan, T.G.5
  • 61
    • 0037767321 scopus 로고    scopus 로고
    • Plasmid stability during in vitro propagation of Borrelia burgdorferi assessed at a clonal level
    • Grimm D, Elias AF, Tilly K, Rosa PA. 2003. Plasmid stability during in vitro propagation of Borrelia burgdorferi assessed at a clonal level. Infect Immun 71: 3138-3145. http://dx.doi.org/10.1128/IAI.71.6.3138-3145.2003.
    • (2003) Infect Immun , vol.71 , pp. 3138-3145
    • Grimm, D.1    Elias, A.F.2    Tilly, K.3    Rosa, P.A.4
  • 62
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorferi
    • Purser JE, Norris SJ. 2000. Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc Natl Acad Sci U S A 97: 13865-13870. http://dx.doi.org/10.1073/pnas.97.25.13865.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 63
    • 1542283705 scopus 로고    scopus 로고
    • Essential role for OspA/B in the life cycle of the Lyme disease spirochete
    • Yang XF, Pal U, Alani SM, Fikrig E, Norgard MV. 2004. Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J Exp Med 199: 641-648. http://dx.doi.org/10.1084/jem.20031960.
    • (2004) J Exp Med , vol.199 , pp. 641-648
    • Yang, X.F.1    Pal, U.2    Alani, S.M.3    Fikrig, E.4    Norgard, M.V.5
  • 64
    • 65249125095 scopus 로고    scopus 로고
    • Borrelia burgdorferi bba74 is expressed exclusively during tick feeding and is regulated by both arthropod- and mammalian host-specific signals
    • Mulay VB, Caimano MJ, Iyer R, Dunham-Ems S, Liveris D, Petzke MM, Schwartz I, Radolf JD. 2009. Borrelia burgdorferi bba74 is expressed exclusively during tick feeding and is regulated by both arthropod- and mammalian host-specific signals. J Bacteriol 191: 2783-2794. http://dx.doi.org/10.1128/JB.01802-08.
    • (2009) J Bacteriol , vol.191 , pp. 2783-2794
    • Mulay, V.B.1    Caimano, M.J.2    Iyer, R.3    Dunham-ems, S.4    Liveris, D.5    Petzke, M.M.6    Schwartz, I.7    Radolf, J.D.8
  • 65
    • 79955764702 scopus 로고    scopus 로고
    • Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation
    • Patton TG, Dietrich G, Dolan MC, Piesman J, Carroll JA, Gilmore RD, Jr. 2011. Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation. PLoS One 6: e19536. http://dx.doi.org/10.1371/journal.pone.0019536.
    • (2011) PLoS One , vol.6 , pp. e19536
    • Patton, T.G.1    Dietrich, G.2    Dolan, M.C.3    Piesman, J.4    Carroll, J.A.5    Gilmore, R.D.6
  • 66
    • 8844239143 scopus 로고    scopus 로고
    • Structure and function of an unusual family of protein phosphatases: The bacterial chemotaxis proteins CheC and CheX
    • Park S, Chao X, Gonzalez-Bonet G, Beel BD, Bilwes AM, Crane BR. 2004. Structure and function of an unusual family of protein phosphatases: the bacterial chemotaxis proteins CheC and CheX. Mol Cell 16: 563-574.
    • (2004) Mol Cell , vol.16 , pp. 563-574
    • Park, S.1    Chao, X.2    Gonzalez-bonet, G.3    Beel, B.D.4    Bilwes, A.M.5    Crane, B.R.6
  • 67
    • 84908548325 scopus 로고    scopus 로고
    • Interactions among the three adaptation systems of Bacillus subtilis chemotaxis as revealed by an in vitro receptor-kinase assay
    • Walukiewicz HE, Tohidifar P, Ordal GW, Rao CV. 2014. Interactions among the three adaptation systems of Bacillus subtilis chemotaxis as revealed by an in vitro receptor-kinase assay. Mol Microbiol 93: 1104-1118. http://dx.doi.org/10.1111/mmi.12721.
    • (2014) Mol Microbiol , vol.93 , pp. 1104-1118
    • Walukiewicz, H.E.1    Tohidifar, P.2    Ordal, G.W.3    Rao, C.V.4
  • 68
    • 0034819849 scopus 로고    scopus 로고
    • Motility and chemotaxis in tissue penetration of oral epithelial cell layers by Treponema denticola
    • Lux R, Miller JN, Park NH, Shi W. 2001. Motility and chemotaxis in tissue penetration of oral epithelial cell layers by Treponema denticola. Infect Immun 69: 6276-6283. http://dx.doi.org/10.1128/IAI.69.10.6276-6283.2001.
    • (2001) Infect Immun , vol.69 , pp. 6276-6283
    • Lux, R.1    Miller, J.N.2    Park, N.H.3    Shi, W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.