메뉴 건너뛰기




Volumn 6, Issue 5, 2011, Pages

Functional analysis of the borrelia burgdorferi bba64 gene product in murine infection via tick infestation

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM MUTANT; BBA64 GENE; BORRELIA BURGDORFERI; CONTROLLED STUDY; DERMIS; FEMALE; GENE EXPRESSION; INFECTION SENSITIVITY; INNATE IMMUNITY; LYME DISEASE; MOUSE; NONHUMAN; NYMPH; PHENOTYPE; SALIVARY GLAND; TICK BITE; TICK INFESTATION; ANIMAL; C57BL MOUSE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; IXODES; METABOLISM; METHODOLOGY; MICROBIOLOGY; MUTATION; PH; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKIN; TRANSGENIC MOUSE;

EID: 79955764702     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019536     Document Type: Article
Times cited : (27)

References (57)
  • 1
    • 0024722869 scopus 로고
    • Epizootiology of Borrelia in Ixodes tick vectors and reservoir hosts
    • Anderson JF, (1989) Epizootiology of Borrelia in Ixodes tick vectors and reservoir hosts. Rev Infect Dis 11 (Suppl 6): S1451-1459.
    • (1989) Rev Infect Dis , vol.11 , Issue.SUPPL. 6
    • Anderson, J.F.1
  • 2
    • 0141671799 scopus 로고    scopus 로고
    • Adaptation of Borrelia burgdorferi in the tick and the mammalian host
    • Anguita J, Hedrick MN, Fikrig E, (2003) Adaptation of Borrelia burgdorferi in the tick and the mammalian host. FEMS Microbiol Rev 27: 493-504.
    • (2003) FEMS Microbiol Rev , vol.27 , pp. 493-504
    • Anguita, J.1    Hedrick, M.N.2    Fikrig, E.3
  • 3
    • 0035849985 scopus 로고    scopus 로고
    • Lyme disease
    • Steere AC, (2001) Lyme disease. N Engl J Med 345: 115-125.
    • (2001) N Engl J Med , vol.345 , pp. 115-125
    • Steere, A.C.1
  • 5
    • 34547965447 scopus 로고    scopus 로고
    • Tick-host-pathogen interactions in Lyme borreliosis
    • Hovius JW, van Dam AP, Fikrig E, (2007) Tick-host-pathogen interactions in Lyme borreliosis. Trends Parasitol 23: 434-438.
    • (2007) Trends Parasitol , vol.23 , pp. 434-438
    • Hovius, J.W.1    van Dam, A.P.2    Fikrig, E.3
  • 6
    • 0032967572 scopus 로고    scopus 로고
    • Effects of environmental pH on membrane proteins in Borrelia burgdorferi
    • Carroll JA, Garon CF, Schwan TG, (1999) Effects of environmental pH on membrane proteins in Borrelia burgdorferi. Infect Immun 67: 3181-3187.
    • (1999) Infect Immun , vol.67 , pp. 3181-3187
    • Carroll, J.A.1    Garon, C.F.2    Schwan, T.G.3
  • 7
    • 0034441169 scopus 로고    scopus 로고
    • Identification of 11 pH-regulated genes in Borrelia burgdorferi localizing to linear plasmids
    • Carroll JA, Cordova RM, Garon CF, (2000) Identification of 11 pH-regulated genes in Borrelia burgdorferi localizing to linear plasmids. Infect Immun 68: 6677-6684.
    • (2000) Infect Immun , vol.68 , pp. 6677-6684
    • Carroll, J.A.1    Cordova, R.M.2    Garon, C.F.3
  • 8
    • 33846247458 scopus 로고    scopus 로고
    • Borrelia burgdorferi alters its gene expression and antigenic profile in response to CO2 levels
    • Hyde JA, Trzeciakowski JP, Skare JT, (2007) Borrelia burgdorferi alters its gene expression and antigenic profile in response to CO2 levels. J Bacteriol 189: 437-445.
    • (2007) J Bacteriol , vol.189 , pp. 437-445
    • Hyde, J.A.1    Trzeciakowski, J.P.2    Skare, J.T.3
  • 9
    • 0345535124 scopus 로고    scopus 로고
    • Profiling of temperature-induced changes in Borrelia burgdorferi gene expression by using whole genome arrays
    • Ojaimi C, Brooks C, Casjens S, Rosa P, Elias A, et al. (2003) Profiling of temperature-induced changes in Borrelia burgdorferi gene expression by using whole genome arrays. Infect Immun 71: 1689-1705.
    • (2003) Infect Immun , vol.71 , pp. 1689-1705
    • Ojaimi, C.1    Brooks, C.2    Casjens, S.3    Rosa, P.4    Elias, A.5
  • 10
    • 0035085033 scopus 로고    scopus 로고
    • Borrelia burgdorferi proteins whose expression is similarly affected by culture temperature and pH
    • Ramamoorthy R, Scholl-Meeker D, (2001) Borrelia burgdorferi proteins whose expression is similarly affected by culture temperature and pH. Infect Immun 69: 2739-2742.
    • (2001) Infect Immun , vol.69 , pp. 2739-2742
    • Ramamoorthy, R.1    Scholl-Meeker, D.2
  • 11
    • 1342323757 scopus 로고    scopus 로고
    • Dissolved oxygen levels alter gene expression and antigen profiles in Borrelia burgdorferi
    • Seshu J, Boylan JA, Gherardini FC, Skare JT, (2004) Dissolved oxygen levels alter gene expression and antigen profiles in Borrelia burgdorferi. Infect Immun 72: 1580-1586.
    • (2004) Infect Immun , vol.72 , pp. 1580-1586
    • Seshu, J.1    Boylan, J.A.2    Gherardini, F.C.3    Skare, J.T.4
  • 12
    • 0028828202 scopus 로고
    • Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi
    • Stevenson B, Schwan TG, Rosa PA, (1995) Temperature-related differential expression of antigens in the Lyme disease spirochete, Borrelia burgdorferi. Infect Immun 63: 4535-4539.
    • (1995) Infect Immun , vol.63 , pp. 4535-4539
    • Stevenson, B.1    Schwan, T.G.2    Rosa, P.A.3
  • 13
    • 0033778628 scopus 로고    scopus 로고
    • Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi
    • Yang X, Goldberg MS, Popova TG, Schoeler GB, Wikel SK, et al. (2000) Interdependence of environmental factors influencing reciprocal patterns of gene expression in virulent Borrelia burgdorferi. Mol Microbiol 37: 1470-1479.
    • (2000) Mol Microbiol , vol.37 , pp. 1470-1479
    • Yang, X.1    Goldberg, M.S.2    Popova, T.G.3    Schoeler, G.B.4    Wikel, S.K.5
  • 14
    • 0037022354 scopus 로고    scopus 로고
    • DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete
    • Revel AT, Talaat AM, Norgard MV, (2002) DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete. Proc Natl Acad Sci U S A 99: 1562-1567.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 1562-1567
    • Revel, A.T.1    Talaat, A.M.2    Norgard, M.V.3
  • 15
    • 4544350205 scopus 로고    scopus 로고
    • Combined effects of blood and temperature shift on Borrelia burgdorferi gene expression as determined by whole genome DNA array
    • Tokarz R, Anderton JM, Katona LI, Benach JL, (2004) Combined effects of blood and temperature shift on Borrelia burgdorferi gene expression as determined by whole genome DNA array. Infect Immun 72: 5419-5432.
    • (2004) Infect Immun , vol.72 , pp. 5419-5432
    • Tokarz, R.1    Anderton, J.M.2    Katona, L.I.3    Benach, J.L.4
  • 16
    • 0032832201 scopus 로고    scopus 로고
    • Evolution of the linear DNA replicons of the Borrelia spirochetes
    • Casjens S, (1999) Evolution of the linear DNA replicons of the Borrelia spirochetes. Curr Opin Microbiol 2: 529-534.
    • (1999) Curr Opin Microbiol , vol.2 , pp. 529-534
    • Casjens, S.1
  • 17
    • 0027527770 scopus 로고
    • Variation in the size of the ospA-containing linear plasmid, but not the linear chromosome, among the three Borrelia species associated with Lyme disease
    • Samuels DS, Marconi RT, Garon CF, (1993) Variation in the size of the ospA-containing linear plasmid, but not the linear chromosome, among the three Borrelia species associated with Lyme disease. J Gen Microbiol 139: 2445-2449.
    • (1993) J Gen Microbiol , vol.139 , pp. 2445-2449
    • Samuels, D.S.1    Marconi, R.T.2    Garon, C.F.3
  • 18
    • 29644440332 scopus 로고    scopus 로고
    • Identification of Borrelia burgdorferi outer surface proteins
    • Brooks CS, Vuppala SR, Jett AM, Akins DR, (2006) Identification of Borrelia burgdorferi outer surface proteins. Infect Immun 74: 296-304.
    • (2006) Infect Immun , vol.74 , pp. 296-304
    • Brooks, C.S.1    Vuppala, S.R.2    Jett, A.M.3    Akins, D.R.4
  • 19
    • 34249868443 scopus 로고    scopus 로고
    • Temporal expression analysis of the Borrelia burgdorferi paralogous gene family 54 genes BBA64, BBA65, and BBA66 during persistent infection in mice
    • Gilmore RD Jr, Howison RR, Schmit VL, Nowalk AJ, Clifton DR, et al. (2007) Temporal expression analysis of the Borrelia burgdorferi paralogous gene family 54 genes BBA64, BBA65, and BBA66 during persistent infection in mice. Infect Immun 75: 2753-2764.
    • (2007) Infect Immun , vol.75 , pp. 2753-2764
    • Gilmore Jr., R.D.1    Howison, R.R.2    Schmit, V.L.3    Nowalk, A.J.4    Clifton, D.R.5
  • 21
    • 1642535449 scopus 로고    scopus 로고
    • Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins
    • Kraiczy P, Hellwage J, Skerka C, Becker H, Kirschfink M, et al. (2004) Complement resistance of Borrelia burgdorferi correlates with the expression of BbCRASP-1, a novel linear plasmid-encoded surface protein that interacts with human factor H and FHL-1 and is unrelated to Erp proteins. J Biol Chem 279: 2421-2429.
    • (2004) J Biol Chem , vol.279 , pp. 2421-2429
    • Kraiczy, P.1    Hellwage, J.2    Skerka, C.3    Becker, H.4    Kirschfink, M.5
  • 22
    • 34047197022 scopus 로고    scopus 로고
    • Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks
    • Neelakanta G, Li X, Pal U, Liu X, Beck DS, et al. (2007) Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks. PLoS Pathog 3: e33.
    • (2007) PLoS Pathog , vol.3
    • Neelakanta, G.1    Li, X.2    Pal, U.3    Liu, X.4    Beck, D.S.5
  • 23
    • 8344262276 scopus 로고    scopus 로고
    • TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi
    • Pal U, Li X, Wang T, Montgomery RR, Ramamoorthi N, et al. (2004) TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi. Cell 119: 457-468.
    • (2004) Cell , vol.119 , pp. 457-468
    • Pal, U.1    Li, X.2    Wang, T.3    Montgomery, R.R.4    Ramamoorthi, N.5
  • 24
    • 1542283705 scopus 로고    scopus 로고
    • Essential role for OspA/B in the life cycle of the Lyme disease spirochete
    • Yang XF, Pal U, Alani SM, Fikrig E, Norgard MV, (2004) Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J Exp Med 199: 641-648.
    • (2004) J Exp Med , vol.199 , pp. 641-648
    • Yang, X.F.1    Pal, U.2    Alani, S.M.3    Fikrig, E.4    Norgard, M.V.5
  • 25
    • 1642528894 scopus 로고    scopus 로고
    • Molecular characterization of a 35-kilodalton protein of Borrelia burgdorferi, an antigen of diagnostic importance in early Lyme disease
    • Gilmore RD Jr, Kappel KJ, Johnson BJ, (1997) Molecular characterization of a 35-kilodalton protein of Borrelia burgdorferi, an antigen of diagnostic importance in early Lyme disease. J Clin Microbiol 35: 86-91.
    • (1997) J Clin Microbiol , vol.35 , pp. 86-91
    • Gilmore Jr., R.D.1    Kappel, K.J.2    Johnson, B.J.3
  • 26
    • 34547879640 scopus 로고    scopus 로고
    • Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle
    • Caimano MJ, Iyer R, Eggers CH, Gonzalez C, Morton EA, et al. (2007) Analysis of the RpoS regulon in Borrelia burgdorferi in response to mammalian host signals provides insight into RpoS function during the enzootic cycle. Mol Microbiol 65: 1193-1217.
    • (2007) Mol Microbiol , vol.65 , pp. 1193-1217
    • Caimano, M.J.1    Iyer, R.2    Eggers, C.H.3    Gonzalez, C.4    Morton, E.A.5
  • 27
    • 38849106830 scopus 로고    scopus 로고
    • Analysis of the determinants of bba64 (P35) gene expression in Borrelia burgdorferi using a gfp reporter
    • Gautam A, Hathaway M, McClain N, Ramesh G, Ramamoorthy R, (2008) Analysis of the determinants of bba64 (P35) gene expression in Borrelia burgdorferi using a gfp reporter. Microbiology 154: 275-285.
    • (2008) Microbiology , vol.154 , pp. 275-285
    • Gautam, A.1    Hathaway, M.2    McClain, N.3    Ramesh, G.4    Ramamoorthy, R.5
  • 28
    • 79251480381 scopus 로고    scopus 로고
    • CsrA modulates levels of lipoproteins and key regulators of gene expression critical for pathogenic mechanisms of Borrelia burgdorferi
    • Karna SL, Sanjuan E, Esteve-Gassent MD, Miller CL, Maruskova M, et al. (2011) CsrA modulates levels of lipoproteins and key regulators of gene expression critical for pathogenic mechanisms of Borrelia burgdorferi. Infect Immun 79: 732-744.
    • (2011) Infect Immun , vol.79 , pp. 732-744
    • Karna, S.L.1    Sanjuan, E.2    Esteve-Gassent, M.D.3    Miller, C.L.4    Maruskova, M.5
  • 29
    • 72049128621 scopus 로고    scopus 로고
    • BosR (BB0647) governs virulence expression in Borrelia burgdorferi
    • Ouyang Z, Kumar M, Kariu T, Haq S, Goldberg M, et al. (2009) BosR (BB0647) governs virulence expression in Borrelia burgdorferi. Mol Microbiol 74: 1331-1343.
    • (2009) Mol Microbiol , vol.74 , pp. 1331-1343
    • Ouyang, Z.1    Kumar, M.2    Kariu, T.3    Haq, S.4    Goldberg, M.5
  • 30
    • 0038104769 scopus 로고    scopus 로고
    • Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals
    • Brooks CS, Hefty PS, Jolliff SE, Akins DR, (2003) Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infect Immun 71: 3371-3383.
    • (2003) Infect Immun , vol.71 , pp. 3371-3383
    • Brooks, C.S.1    Hefty, P.S.2    Jolliff, S.E.3    Akins, D.R.4
  • 31
    • 0034802110 scopus 로고    scopus 로고
    • Analysis of Borrelia burgdorferi gene expression during life cycle phases of the tick vector Ixodes scapularis
    • Gilmore RD Jr, Mbow ML, Stevenson B, (2001) Analysis of Borrelia burgdorferi gene expression during life cycle phases of the tick vector Ixodes scapularis. Microbes Infect 3: 799-808.
    • (2001) Microbes Infect , vol.3 , pp. 799-808
    • Gilmore Jr., R.D.1    Mbow, M.L.2    Stevenson, B.3
  • 32
    • 0030951048 scopus 로고    scopus 로고
    • Cell-density-dependent expression of Borrelia burgdorferi lipoproteins in vitro
    • Indest KJ, Ramamoorthy R, Sole M, Gilmore RD, Johnson BJ, et al. (1997) Cell-density-dependent expression of Borrelia burgdorferi lipoproteins in vitro. Infect Immun 65: 1165-1171.
    • (1997) Infect Immun , vol.65 , pp. 1165-1171
    • Indest, K.J.1    Ramamoorthy, R.2    Sole, M.3    Gilmore, R.D.4    Johnson, B.J.5
  • 33
    • 77952166427 scopus 로고    scopus 로고
    • The bba64 gene of Borrelia burgdorferi, the Lyme disease agent, is critical for mammalian infection via tick bite transmission
    • Gilmore RD Jr, Howison RR, Dietrich G, Patton TG, Clifton DR, et al. (2010) The bba64 gene of Borrelia burgdorferi, the Lyme disease agent, is critical for mammalian infection via tick bite transmission. Proc Natl Acad Sci U S A 107: 7515-7520.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 7515-7520
    • Gilmore Jr., R.D.1    Howison, R.R.2    Dietrich, G.3    Patton, T.G.4    Clifton, D.R.5
  • 34
    • 37749028452 scopus 로고    scopus 로고
    • Role of the BBA64 locus of Borrelia burgdorferi in early stages of infectivity in a murine model of Lyme disease
    • Maruskova M, Esteve-Gassent MD, Sexton VL, Seshu J, (2008) Role of the BBA64 locus of Borrelia burgdorferi in early stages of infectivity in a murine model of Lyme disease. Infect Immun 76: 391-402.
    • (2008) Infect Immun , vol.76 , pp. 391-402
    • Maruskova, M.1    Esteve-Gassent, M.D.2    Sexton, V.L.3    Seshu, J.4
  • 36
    • 0033984294 scopus 로고    scopus 로고
    • Temporal changes in outer surface proteins A and C of the lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice
    • Schwan TG, Piesman J, (2000) Temporal changes in outer surface proteins A and C of the lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice. J Clin Microbiol 38: 382-388.
    • (2000) J Clin Microbiol , vol.38 , pp. 382-388
    • Schwan, T.G.1    Piesman, J.2
  • 37
    • 70350440467 scopus 로고    scopus 로고
    • GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle
    • Jewett MW, Lawrence KA, Bestor A, Byram R, Gherardini F, et al. (2009) GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle. J Bacteriol 191: 6231-6241.
    • (2009) J Bacteriol , vol.191 , pp. 6231-6241
    • Jewett, M.W.1    Lawrence, K.A.2    Bestor, A.3    Byram, R.4    Gherardini, F.5
  • 38
    • 18744400258 scopus 로고    scopus 로고
    • bptA (bbe16) is essential for the persistence of the Lyme disease spirochete, Borrelia burgdorferi, in its natural tick vector
    • Revel AT, Blevins JS, Almazan C, Neil L, Kocan KM, et al. (2005) bptA (bbe16) is essential for the persistence of the Lyme disease spirochete, Borrelia burgdorferi, in its natural tick vector. Proc Natl Acad Sci U S A 102: 6972-6977.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 6972-6977
    • Revel, A.T.1    Blevins, J.S.2    Almazan, C.3    Neil, L.4    Kocan, K.M.5
  • 39
    • 70349428512 scopus 로고    scopus 로고
    • BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle
    • Zhang X, Yang X, Kumar M, Pal U, (2009) BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle. J Infect Dis 200: 1318-1330.
    • (2009) J Infect Dis , vol.200 , pp. 1318-1330
    • Zhang, X.1    Yang, X.2    Kumar, M.3    Pal, U.4
  • 40
    • 33846217722 scopus 로고    scopus 로고
    • The Lyme disease agent Borrelia burgdorferi requires BB0690, a Dps homologue, to persist within ticks
    • Li X, Pal U, Ramamoorthi N, Liu X, Desrosiers DC, et al. (2007) The Lyme disease agent Borrelia burgdorferi requires BB0690, a Dps homologue, to persist within ticks. Mol Microbiol 63: 694-710.
    • (2007) Mol Microbiol , vol.63 , pp. 694-710
    • Li, X.1    Pal, U.2    Ramamoorthi, N.3    Liu, X.4    Desrosiers, D.C.5
  • 41
    • 39349089426 scopus 로고    scopus 로고
    • A differential role for BB0365 in the persistence of Borrelia burgdorferi in mice and ticks
    • Pal U, Dai J, Li X, Neelakanta G, Luo P, et al. (2008) A differential role for BB0365 in the persistence of Borrelia burgdorferi in mice and ticks. J Infect Dis 197: 148-155.
    • (2008) J Infect Dis , vol.197 , pp. 148-155
    • Pal, U.1    Dai, J.2    Li, X.3    Neelakanta, G.4    Luo, P.5
  • 42
    • 0023248582 scopus 로고
    • Adult Ixodes dammini on rabbits: a hypothesis for the development and transmission of Borrelia burgdorferi
    • Benach JL, Coleman JL, Skinner RA, Bosler EM, (1987) Adult Ixodes dammini on rabbits: a hypothesis for the development and transmission of Borrelia burgdorferi. J Infect Dis 155: 1300-1306.
    • (1987) J Infect Dis , vol.155 , pp. 1300-1306
    • Benach, J.L.1    Coleman, J.L.2    Skinner, R.A.3    Bosler, E.M.4
  • 43
    • 0028842880 scopus 로고
    • Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding
    • De Silva AM, Fikrig E, (1995) Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding. Am J Trop Med Hyg 53: 397-404.
    • (1995) Am J Trop Med Hyg , vol.53 , pp. 397-404
    • de Silva, A.M.1    Fikrig, E.2
  • 44
    • 0023100179 scopus 로고
    • Dissemination and salivary delivery of Lyme disease spirochetes in vector ticks (Acari: Ixodidae)
    • Ribeiro JM, Mather TN, Piesman J, Spielman A, (1987) Dissemination and salivary delivery of Lyme disease spirochetes in vector ticks (Acari: Ixodidae). J Med Entomol 24: 201-205.
    • (1987) J Med Entomol , vol.24 , pp. 201-205
    • Ribeiro, J.M.1    Mather, T.N.2    Piesman, J.3    Spielman, A.4
  • 45
    • 79953221166 scopus 로고    scopus 로고
    • Detection of Borrelia burgdorferi DNA in tick feces provides evidence for organism shedding during vector feeding
    • Patton TG, Dietrich G, Gilmore RD, (2011) Detection of Borrelia burgdorferi DNA in tick feces provides evidence for organism shedding during vector feeding. Vector Borne Zoonotic Dis 33: 197-200.
    • (2011) Vector Borne Zoonotic Dis , vol.33 , pp. 197-200
    • Patton, T.G.1    Dietrich, G.2    Gilmore, R.D.3
  • 46
    • 20544474210 scopus 로고    scopus 로고
    • Pathogen recognition with Toll-like receptors
    • Kawai T, Akira S, (2005) Pathogen recognition with Toll-like receptors. Curr Opin Immunol 17: 338-344.
    • (2005) Curr Opin Immunol , vol.17 , pp. 338-344
    • Kawai, T.1    Akira, S.2
  • 47
    • 0032133278 scopus 로고    scopus 로고
    • MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways
    • Medzhitov R, Preston-Hurlburt P, Kopp E, Stadlen A, Chen C, et al. (1998) MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways. Mol Cell 2: 253-258.
    • (1998) Mol Cell , vol.2 , pp. 253-258
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Kopp, E.3    Stadlen, A.4    Chen, C.5
  • 48
    • 33645510634 scopus 로고    scopus 로고
    • MyD88 deficiency enhances acquisition and transmission of Borrelia burgdorferi by Ixodes scapularis ticks
    • Bockenstedt LK, Liu N, Schwartz I, Fish D, (2006) MyD88 deficiency enhances acquisition and transmission of Borrelia burgdorferi by Ixodes scapularis ticks. Infect Immun 74: 2154-2160.
    • (2006) Infect Immun , vol.74 , pp. 2154-2160
    • Bockenstedt, L.K.1    Liu, N.2    Schwartz, I.3    Fish, D.4
  • 49
    • 14844317314 scopus 로고    scopus 로고
    • Chemokines and Toll-like receptors in Lyme disease pathogenesis
    • Guerau-de-Arellano M, Huber BT, (2005) Chemokines and Toll-like receptors in Lyme disease pathogenesis. Trends Mol Med 11: 114-120.
    • (2005) Trends Mol Med , vol.11 , pp. 114-120
    • Guerau-de-Arellano, M.1    Huber, B.T.2
  • 50
    • 77749308350 scopus 로고    scopus 로고
    • BBA52 facilitates Borrelia burgdorferi transmission from feeding ticks to murine hosts
    • Kumar M, Yang X, Coleman AS, Pal U, (2010) BBA52 facilitates Borrelia burgdorferi transmission from feeding ticks to murine hosts. J Infect Dis 201: 1084-1095.
    • (2010) J Infect Dis , vol.201 , pp. 1084-1095
    • Kumar, M.1    Yang, X.2    Coleman, A.S.3    Pal, U.4
  • 51
    • 70350143371 scopus 로고    scopus 로고
    • Borrelia burgdorferi small lipoprotein Lp6.6 is a member of multiple protein complexes in the outer membrane and facilitates pathogen transmission from ticks to mice
    • Promnares K, Kumar M, Shroder DY, Zhang X, Anderson JF, et al. (2009) Borrelia burgdorferi small lipoprotein Lp6.6 is a member of multiple protein complexes in the outer membrane and facilitates pathogen transmission from ticks to mice. Mol Microbiol 74: 112-125.
    • (2009) Mol Microbiol , vol.74 , pp. 112-125
    • Promnares, K.1    Kumar, M.2    Shroder, D.Y.3    Zhang, X.4    Anderson, J.F.5
  • 52
    • 77953952245 scopus 로고    scopus 로고
    • Role of the surface lipoprotein BBA07 in the enzootic cycle of Borrelia burgdorferi
    • Xu H, He M, He JJ, Yang XF, (2010) Role of the surface lipoprotein BBA07 in the enzootic cycle of Borrelia burgdorferi. Infect Immun 78: 2910-2918.
    • (2010) Infect Immun , vol.78 , pp. 2910-2918
    • Xu, H.1    He, M.2    He, J.J.3    Yang, X.F.4
  • 53
    • 0036126988 scopus 로고    scopus 로고
    • Clonal polymorphism of Borrelia burgdorferi strain B31 MI: implications for mutagenesis in an infectious strain background
    • Elias AF, Stewart PE, Grimm D, Caimano MJ, Eggers CH, et al. (2002) Clonal polymorphism of Borrelia burgdorferi strain B31 MI: implications for mutagenesis in an infectious strain background. Infect Immun 70: 2139-2150.
    • (2002) Infect Immun , vol.70 , pp. 2139-2150
    • Elias, A.F.1    Stewart, P.E.2    Grimm, D.3    Caimano, M.J.4    Eggers, C.H.5
  • 54
    • 0027357117 scopus 로고
    • Standard system for infecting ticks (Acari: Ixodidae) with the Lyme disease spirochete, Borrelia burgdorferi
    • Piesman J, (1993) Standard system for infecting ticks (Acari: Ixodidae) with the Lyme disease spirochete, Borrelia burgdorferi. J Med Entomol 30: 199-203.
    • (1993) J Med Entomol , vol.30 , pp. 199-203
    • Piesman, J.1
  • 55
    • 0024365376 scopus 로고
    • Ear punch biopsy method for detection and isolation of Borrelia burgdorferi from rodents
    • Sinsky RJ, Piesman J, (1989) Ear punch biopsy method for detection and isolation of Borrelia burgdorferi from rodents. J Clin Microbiol 27: 1723-1727.
    • (1989) J Clin Microbiol , vol.27 , pp. 1723-1727
    • Sinsky, R.J.1    Piesman, J.2
  • 56
    • 0028117289 scopus 로고
    • Absence of acquired resistance to nymphal Ixodes ricinus ticks in BALB/c mice developing cutaneous reactions
    • Mbow ML, Christe M, Rutti B, Brossard M, (1994) Absence of acquired resistance to nymphal Ixodes ricinus ticks in BALB/c mice developing cutaneous reactions. J Parasitol 80: 81-87.
    • (1994) J Parasitol , vol.80 , pp. 81-87
    • Mbow, M.L.1    Christe, M.2    Rutti, B.3    Brossard, M.4
  • 57
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.