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Volumn 81, Issue 6, 2013, Pages 2012-2021

Motility is crucial for the infectious life cycle of borrelia burgdorferi

Author keywords

[No Author keywords available]

Indexed keywords

PLASMID DNA;

EID: 84877811303     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01228-12     Document Type: Article
Times cited : (64)

References (117)
  • 4
    • 84855900042 scopus 로고    scopus 로고
    • Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes
    • Radolf JD, Caimano MJ, Stevenson B, Hu LT. 2012. Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes. Nat. Rev. Microbiol. 10:87-99.
    • (2012) Nat. Rev. Microbiol. , vol.10 , pp. 87-99
    • Radolf, J.D.1    Caimano, M.J.2    Stevenson, B.3    Hu, L.T.4
  • 6
    • 79953281641 scopus 로고    scopus 로고
    • Tick interactions
    • Samuels DS, Radolf JD (ed), Caister Academic Press, Norfolk, United Kingdom
    • Pal U, Fikrig E. 2010. Tick interactions, p 279-298. In Samuels DS, Radolf JD (ed), Borrelia: molecular biology, host interaction and pathogenesis. Caister Academic Press, Norfolk, United Kingdom.
    • (2010) Borrelia: molecular biology, host interaction and pathogenesis , pp. 279-298
    • Pal, U.1    Fikrig, E.2
  • 7
    • 0023100179 scopus 로고
    • Dissemination and salivary delivery of Lyme disease spirochetes in vector ticks (Acari: Ixodidae)
    • Ribeiro JM, Mather TN, Piesman J, Spielman A. 1987. Dissemination and salivary delivery of Lyme disease spirochetes in vector ticks (Acari: Ixodidae). J. Med. Entomol. 24:201-205.
    • (1987) J. Med. Entomol. , vol.24 , pp. 201-205
    • Ribeiro, J.M.1    Mather, T.N.2    Piesman, J.3    Spielman, A.4
  • 8
    • 77949392836 scopus 로고    scopus 로고
    • Inactivation of a putative flagellar motor switch protein FliG1 prevents Borrelia burgdorferi from swimming in highly viscous media and blocks its infectivity
    • Li C, Xu H, Zhang K, Liang FT. 2010. Inactivation of a putative flagellar motor switch protein FliG1 prevents Borrelia burgdorferi from swimming in highly viscous media and blocks its infectivity. Mol. Microbiol. 75:1563-1576.
    • (2010) Mol. Microbiol. , vol.75 , pp. 1563-1576
    • Li, C.1    Xu, H.2    Zhang, K.3    Liang, F.T.4
  • 9
    • 84864821396 scopus 로고    scopus 로고
    • Borrelia burgdorferi needs chemotaxis to establish infection in mammals and to accomplish its enzootic cycle
    • Sze CW, Zhang K, Kariu T, Pal U, Li C. 2012. Borrelia burgdorferi needs chemotaxis to establish infection in mammals and to accomplish its enzootic cycle. Infect. Immun. 80:2485-2492.
    • (2012) Infect. Immun. , vol.80 , pp. 2485-2492
    • Sze, C.W.1    Zhang, K.2    Kariu, T.3    Pal, U.4    Li, C.5
  • 10
    • 46449086457 scopus 로고    scopus 로고
    • Real-time high resolution 3D imaging of the Lyme disease spirochete adhering to and escaping from the vasculature of a living host
    • doi:10.1371/journal.ppat.1000090
    • Moriarty TJ, Norman MU, Colarusso P, Bankhead T, Kubes P, Chaconas G. 2008. Real-time high resolution 3D imaging of the Lyme disease spirochete adhering to and escaping from the vasculature of a living host. PLoS Pathog. 4:e1000090. doi:10.1371/journal.ppat.1000090.
    • (2008) PLoS Pathog. , vol.4
    • Moriarty, T.J.1    Norman, M.U.2    Colarusso, P.3    Bankhead, T.4    Kubes, P.5    Chaconas, G.6
  • 11
    • 55449126064 scopus 로고    scopus 로고
    • Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host
    • doi:10 .1371/journal.ppat.1000169
    • Norman MU, Moriarty TJ, Dresser AR, Millen B, Kubes P, Chaconas G. 2008. Molecular mechanisms involved in vascular interactions of the Lyme disease pathogen in a living host. PLoS Pathog. 4:e1000169. doi:10 .1371/journal.ppat.1000169.
    • (2008) PLoS Pathog. , vol.4
    • Norman, M.U.1    Moriarty, T.J.2    Dresser, A.R.3    Millen, B.4    Kubes, P.5    Chaconas, G.6
  • 13
    • 45449115552 scopus 로고    scopus 로고
    • Clocking the Lyme spirochete
    • doi:10.1371/journal.pone.0001633
    • Malawista SE, de Boisfleury CA. 2008. Clocking the Lyme spirochete. PLoS One 3:e1633. doi:10.1371/journal.pone.0001633.
    • (2008) PLoS One , vol.3
    • Malawista, S.E.1    de Boisfleury, C.A.2
  • 19
    • 79956117013 scopus 로고    scopus 로고
    • Chemoreceptors and flagellar motors are subterminally located in close proximity at the two cell poles in spirochetes
    • Xu H, Raddi G, Liu J, Charon NW, Li C. 2011. Chemoreceptors and flagellar motors are subterminally located in close proximity at the two cell poles in spirochetes. J. Bacteriol. 193:2652-2656.
    • (2011) J. Bacteriol. , vol.193 , pp. 2652-2656
    • Xu, H.1    Raddi, G.2    Liu, J.3    Charon, N.W.4    Li, C.5
  • 20
    • 0036948288 scopus 로고    scopus 로고
    • Genetics of motility and chemotaxis of a fascinating group of bacteria: the spirochetes
    • Charon NW, Goldstein SF. 2002. Genetics of motility and chemotaxis of a fascinating group of bacteria: the spirochetes. Annu. Rev. Genet. 36:47-73.
    • (2002) Annu. Rev. Genet. , vol.36 , pp. 47-73
    • Charon, N.W.1    Goldstein, S.F.2
  • 25
    • 67749093018 scopus 로고    scopus 로고
    • Intact flagellar motor of Borrelia burgdorferi revealed by cryo-electron tomography: evidence for stator ring curvature and rotor/C-ring assembly flexion
    • Liu J, Lin T, Botkin DJ, McCrum E, Winkler H, Norris SJ. 2009. Intact flagellar motor of Borrelia burgdorferi revealed by cryo-electron tomography: evidence for stator ring curvature and rotor/C-ring assembly flexion. J. Bacteriol. 191:5026-5036.
    • (2009) J. Bacteriol. , vol.191 , pp. 5026-5036
    • Liu, J.1    Lin, T.2    Botkin, D.J.3    McCrum, E.4    Winkler, H.5    Norris, S.J.6
  • 26
    • 40449134876 scopus 로고    scopus 로고
    • Borrelia burgdorferi uniquely regulates its motility genes and has an intricate flagellar hook-basal body structure
    • Sal MS, Li C, Motalab MA, Shibata S, Aizawa S, Charon NW. 2008. Borrelia burgdorferi uniquely regulates its motility genes and has an intricate flagellar hook-basal body structure. J. Bacteriol. 190:1912-1921.
    • (2008) J. Bacteriol. , vol.190 , pp. 1912-1921
    • Sal, M.S.1    Li, C.2    Motalab, M.A.3    Shibata, S.4    Aizawa, S.5    Charon, N.W.6
  • 27
    • 84863130864 scopus 로고    scopus 로고
    • A single-domain FlgJ contributes to flagellar hook and filament formation in the Lyme disease spirochete Borrelia burgdorferi
    • Zhang K, Tong BA, Liu J, Li C. 2012. A single-domain FlgJ contributes to flagellar hook and filament formation in the Lyme disease spirochete Borrelia burgdorferi. J. Bacteriol. 194:866-874.
    • (2012) J. Bacteriol. , vol.194 , pp. 866-874
    • Zhang, K.1    Tong, B.A.2    Liu, J.3    Li, C.4
  • 28
    • 0031965752 scopus 로고    scopus 로고
    • Structure and expression of the FlaA periplasmic flagellar protein of Borrelia burgdorferi
    • Ge Y, Li C, Corum L, Slaughter CA, Charon NW. 1998. Structure and expression of the FlaA periplasmic flagellar protein of Borrelia burgdorferi. J. Bacteriol. 180:2418-2425.
    • (1998) J. Bacteriol. , vol.180 , pp. 2418-2425
    • Ge, Y.1    Li, C.2    Corum, L.3    Slaughter, C.A.4    Charon, N.W.5
  • 29
    • 2942605826 scopus 로고    scopus 로고
    • The decrease in FlaA observed in a flaB mutant of Borrelia burgdorferi occurs posttranscriptionally
    • Motaleb MA, Sal MS, Charon NW. 2004. The decrease in FlaA observed in a flaB mutant of Borrelia burgdorferi occurs posttranscriptionally. J. Bacteriol. 186:3703-3711.
    • (2004) J. Bacteriol. , vol.186 , pp. 3703-3711
    • Motaleb, M.A.1    Sal, M.S.2    Charon, N.W.3
  • 30
    • 49449118209 scopus 로고    scopus 로고
    • Genetic analysis of spirochete flagellin proteins and their involvement in motility, filament assembly, and flagellar morphology
    • Li C, Wolgemuth CW, Marko M, Morgan DG, Charon NW. 2008. Genetic analysis of spirochete flagellin proteins and their involvement in motility, filament assembly, and flagellar morphology. J. Bacteriol. 190: 5607-5615.
    • (2008) J. Bacteriol. , vol.190 , pp. 5607-5615
    • Li, C.1    Wolgemuth, C.W.2    Marko, M.3    Morgan, D.G.4    Charon, N.W.5
  • 31
    • 68449102172 scopus 로고    scopus 로고
    • Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans
    • Malmström J, Beck M, Schmidt A, Lange V, Deutsch EW, Aebersold R. 2009. Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans. Nature 460:762-765.
    • (2009) Nature , vol.460 , pp. 762-765
    • Malmström, J.1    Beck, M.2    Schmidt, A.3    Lange, V.4    Deutsch, E.W.5    Aebersold, R.6
  • 32
    • 85047688053 scopus 로고    scopus 로고
    • FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath
    • Lambert A, Picardeau M, Haake DA, Sermswan RW, Srikram A, Adler B, Murray GA. 2012. FlaA proteins in Leptospira interrogans are essential for motility and virulence but are not required for formation of the flagellum sheath. Infect. Immun. 80:2019-2025.
    • (2012) Infect. Immun. , vol.80 , pp. 2019-2025
    • Lambert, A.1    Picardeau, M.2    Haake, D.A.3    Sermswan, R.W.4    Srikram, A.5    Adler, B.6    Murray, G.A.7
  • 33
    • 77952061602 scopus 로고    scopus 로고
    • Differential regulation of the multiple flagellins in spirochetes
    • Li C, Sal M, Marko M, Charon NW. 2010. Differential regulation of the multiple flagellins in spirochetes. J. Bacteriol. 192:2596-2603.
    • (2010) J. Bacteriol. , vol.192 , pp. 2596-2603
    • Li, C.1    Sal, M.2    Marko, M.3    Charon, N.W.4
  • 34
    • 0030873720 scopus 로고    scopus 로고
    • - mutants of Serpulina hyodysenteriae: both flagellin subunits, FlaA and FlaB, are necessary for full motility and intestinal colonization
    • - mutants of Serpulina hyodysenteriae: both flagellin subunits, FlaA and FlaB, are necessary for full motility and intestinal colonization. FEMS Microbiol. Lett. 153:119-128.
    • (1997) FEMS Microbiol. Lett. , vol.153 , pp. 119-128
    • Kennedy, M.J.1    Rosey, E.L.2    Yancey Jr., R.J.3
  • 35
    • 0029838666 scopus 로고    scopus 로고
    • Dual flaA1 flaB1 mutant of Serpulina hyodysenteriae expressing periplasmic flagella is severely attenuated in a murine model of swine dysentery
    • Rosey EL, Kennedy MJ, Yancey RJ, Jr. 1996. Dual flaA1 flaB1 mutant of Serpulina hyodysenteriae expressing periplasmic flagella is severely attenuated in a murine model of swine dysentery. Infect. Immun. 64:4154-4162.
    • (1996) Infect. Immun. , vol.64 , pp. 4154-4162
    • Rosey, E.L.1    Kennedy, M.J.2    Yancey Jr., R.J.3
  • 36
    • 0035050686 scopus 로고    scopus 로고
    • First evidence for gene replacement in Leptospira spp. Inactivation of L. biflexa flaB results in non-motile mutants deficient in endoflagella
    • Picardeau M, Brenot A, Saint Girons I. 2001. First evidence for gene replacement in Leptospira spp. Inactivation of L. biflexa flaB results in non-motile mutants deficient in endoflagella. Mol. Microbiol. 40:189-199.
    • (2001) Mol. Microbiol. , vol.40 , pp. 189-199
    • Picardeau, M.1    Brenot, A.2    Saint Girons, I.3
  • 37
    • 0025766135 scopus 로고
    • The bent-end morphology of Treponema phagedenis is associated with short, lefthanded, periplasmic flagella
    • Charon NW, Goldstein SF, Curci K, Limberger RJ. 1991. The bent-end morphology of Treponema phagedenis is associated with short, lefthanded, periplasmic flagella. J. Bacteriol. 173:4820-4826.
    • (1991) J. Bacteriol. , vol.173 , pp. 4820-4826
    • Charon, N.W.1    Goldstein, S.F.2    Curci, K.3    Limberger, R.J.4
  • 39
    • 0034462476 scopus 로고    scopus 로고
    • The spirochete FlaA periplasmic flagellar sheath protein impacts flagellar helicity
    • Li C, Corum L, Morgan D, Rosey EL, Stanton TB, Charon NW. 2000. The spirochete FlaA periplasmic flagellar sheath protein impacts flagellar helicity. J. Bacteriol. 182:6698-6706.
    • (2000) J. Bacteriol. , vol.182 , pp. 6698-6706
    • Li, C.1    Corum, L.2    Morgan, D.3    Rosey, E.L.4    Stanton, T.B.5    Charon, N.W.6
  • 40
    • 0036128606 scopus 로고    scopus 로고
    • Helicobacter pylori uses motility for initial colonization and to attain robust infection
    • Ottemann KM, Lowenthal AC. 2002. Helicobacter pylori uses motility for initial colonization and to attain robust infection. Infect. Immun. 70:1984-1990.
    • (2002) Infect. Immun. , vol.70 , pp. 1984-1990
    • Ottemann, K.M.1    Lowenthal, A.C.2
  • 41
    • 33846948997 scopus 로고    scopus 로고
    • Bacterial factors that mediate colonization of the stomach and virulence of Helicobacter pylori
    • Clyne M, Dolan B, Reeves EP. 2007. Bacterial factors that mediate colonization of the stomach and virulence of Helicobacter pylori. FEMS Microbiol. Lett. 268:135-143.
    • (2007) FEMS Microbiol. Lett. , vol.268 , pp. 135-143
    • Clyne, M.1    Dolan, B.2    Reeves, E.P.3
  • 42
    • 1842737591 scopus 로고    scopus 로고
    • Both chemotaxis and net motility greatly influence the infectivity of Vibrio cholerae
    • Butler SM, Camilli A. 2004. Both chemotaxis and net motility greatly influence the infectivity of Vibrio cholerae. Proc. Natl. Acad. Sci. U. S. A. 101:5018-5023.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 5018-5023
    • Butler, S.M.1    Camilli, A.2
  • 43
    • 22944444886 scopus 로고    scopus 로고
    • Going against the grain: chemotaxis and infection in Vibrio cholerae
    • Butler SM, Camilli A. 2005. Going against the grain: chemotaxis and infection in Vibrio cholerae. Nat. Rev. Microbiol. 3:611-620.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 611-620
    • Butler, S.M.1    Camilli, A.2
  • 44
    • 0036221572 scopus 로고    scopus 로고
    • The role of motility as a virulence factor in bacteria
    • Josenhans C, Suerbaum S. 2002. The role of motility as a virulence factor in bacteria. Int. J. Med. Microbiol. 291:605-614.
    • (2002) Int. J. Med. Microbiol. , vol.291 , pp. 605-614
    • Josenhans, C.1    Suerbaum, S.2
  • 45
    • 73449089074 scopus 로고    scopus 로고
    • Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogans strain Lai
    • doi:10.1186/1471-2180-9-253
    • Liao S, Sun A, Ojcius DM, Wu S, Zhao J, Yan J. 2009. Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogans strain Lai. BMC Microbiol. 9:253. doi:10.1186/1471-2180-9-253.
    • (2009) BMC Microbiol. , vol.9 , pp. 253
    • Liao, S.1    Sun, A.2    Ojcius, D.M.3    Wu, S.4    Zhao, J.5    Yan, J.6
  • 46
    • 33845501160 scopus 로고    scopus 로고
    • Identification of potential virulence determinants by Himar1 transposition of infectious Borrelia burgdorferi B31
    • Botkin DJ, Abbott AN, Stewart PE, Rosa PA, Kawabata H, Watanabe H, Norris SJ. 2006. Identification of potential virulence determinants by Himar1 transposition of infectious Borrelia burgdorferi B31. Infect. Immun. 74:6690-6699.
    • (2006) Infect. Immun. , vol.74 , pp. 6690-6699
    • Botkin, D.J.1    Abbott, A.N.2    Stewart, P.E.3    Rosa, P.A.4    Kawabata, H.5    Watanabe, H.6    Norris, S.J.7
  • 48
    • 0034751688 scopus 로고    scopus 로고
    • Complementation of a nonmotile flaB mutant of Borrelia burgdorferi by chromosomal integration of a plasmid containing a wild-type flaB allele
    • Sartakova ML, Dobrikova EY, Motaleb MA, Godfrey HP, Charon NW, Cabello FC. 2001. Complementation of a nonmotile flaB mutant of Borrelia burgdorferi by chromosomal integration of a plasmid containing a wild-type flaB allele. J. Bacteriol. 183:6558-6564.
    • (2001) J. Bacteriol. , vol.183 , pp. 6558-6564
    • Sartakova, M.L.1    Dobrikova, E.Y.2    Motaleb, M.A.3    Godfrey, H.P.4    Charon, N.W.5    Cabello, F.C.6
  • 52
    • 70350440467 scopus 로고    scopus 로고
    • GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle
    • Jewett MW, Lawrence KA, Bestor A, Byram R, Gherardini F, Rosa PA. 2009. GuaA and GuaB are essential for Borrelia burgdorferi survival in the tick-mouse infection cycle. J. Bacteriol. 191:6231-6241.
    • (2009) J. Bacteriol. , vol.191 , pp. 6231-6241
    • Jewett, M.W.1    Lawrence, K.A.2    Bestor, A.3    Byram, R.4    Gherardini, F.5    Rosa, P.A.6
  • 53
    • 85058203355 scopus 로고    scopus 로고
    • Isolation and characterization of chemotaxis mutants of the Lyme disease spirochete Borrelia burgdorferi using allelic exchange mutagenesis, flow cytometry, and cell tracking
    • Motaleb MA, Miller MR, Bakker RG, Li C, Charon NW. 2007. Isolation and characterization of chemotaxis mutants of the Lyme disease spirochete Borrelia burgdorferi using allelic exchange mutagenesis, flow cytometry, and cell tracking. Methods Enzymol. 422:421-437.
    • (2007) Methods Enzymol. , vol.422 , pp. 421-437
    • Motaleb, M.A.1    Miller, M.R.2    Bakker, R.G.3    Li, C.4    Charon, N.W.5
  • 54
    • 40549124649 scopus 로고    scopus 로고
    • Transposon mutagenesis of the Lyme disease agent Borrelia burgdorferi
    • Stewart PE, Rosa PA. 2008. Transposon mutagenesis of the Lyme disease agent Borrelia burgdorferi. Methods Mol. Biol. 431:85-95.
    • (2008) Methods Mol. Biol. , vol.431 , pp. 85-95
    • Stewart, P.E.1    Rosa, P.A.2
  • 56
    • 79959410913 scopus 로고    scopus 로고
    • Analysis of the Borrelia burgdorferi cyclic-di-GMP binding protein PlzA reveals a role in motility and virulence
    • Pitzer JE, Sultan SZ, Hayakawa Y, Hobbs G, Miller MR, Motaleb MA. 2011. Analysis of the Borrelia burgdorferi cyclic-di-GMP binding protein PlzA reveals a role in motility and virulence. Infect. Immun. 79:1815-1825.
    • (2011) Infect. Immun. , vol.79 , pp. 1815-1825
    • Pitzer, J.E.1    Sultan, S.Z.2    Hayakawa, Y.3    Hobbs, G.4    Miller, M.R.5    Motaleb, M.A.6
  • 57
    • 77953988576 scopus 로고    scopus 로고
    • Analysis of a Borrelia burgdorferi phosphodiesterase demonstrates a role for cyclic-diguanosine monophosphate in motility and virulence
    • Sultan SZ, Pitzer JE, Miller MR, Motaleb MA. 2010. Analysis of a Borrelia burgdorferi phosphodiesterase demonstrates a role for cyclic-diguanosine monophosphate in motility and virulence. Mol. Microbiol. 77:128-142.
    • (2010) Mol. Microbiol. , vol.77 , pp. 128-142
    • Sultan, S.Z.1    Pitzer, J.E.2    Miller, M.R.3    Motaleb, M.A.4
  • 59
    • 57349152190 scopus 로고    scopus 로고
    • In vitro CpG methylation increases the transformation efficiency of Borrelia burgdorferi strains harboring the endogenous linear plasmid lp56
    • Chen Q, Fischer JR, Benoit VM, Dufour NP, Youderian P, Leong JM. 2008. In vitro CpG methylation increases the transformation efficiency of Borrelia burgdorferi strains harboring the endogenous linear plasmid lp56. J. Bacteriol. 190:7885-7891.
    • (2008) J. Bacteriol. , vol.190 , pp. 7885-7891
    • Chen, Q.1    Fischer, J.R.2    Benoit, V.M.3    Dufour, N.P.4    Youderian, P.5    Leong, J.M.6
  • 61
    • 4644249919 scopus 로고    scopus 로고
    • Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycle
    • Grimm D, Eggers CH, Caimano MJ, Tilly K, Stewart PE, Elias AF, Radolf JD, Rosa PA. 2004. Experimental assessment of the roles of linear plasmids lp25 and lp28-1 of Borrelia burgdorferi throughout the infectious cycle. Infect. Immun. 72:5938-5946.
    • (2004) Infect. Immun. , vol.72 , pp. 5938-5946
    • Grimm, D.1    Eggers, C.H.2    Caimano, M.J.3    Tilly, K.4    Stewart, P.E.5    Elias, A.F.6    Radolf, J.D.7    Rosa, P.A.8
  • 63
    • 79961113805 scopus 로고    scopus 로고
    • Analysis of the HD-GYP domain cyclic-di-GMP phosphodiesterase reveals a role in motility and enzootic life cycle of Borrelia burgdorferi
    • Sultan SZ, Pitzer JE, Boquoi T, Hobbs G, Miller MR, Motaleb MA. 2011. Analysis of the HD-GYP domain cyclic-di-GMP phosphodiesterase reveals a role in motility and enzootic life cycle of Borrelia burgdorferi. Infect. Immun. 79:3273-3283.
    • (2011) Infect. Immun. , vol.79 , pp. 3273-3283
    • Sultan, S.Z.1    Pitzer, J.E.2    Boquoi, T.3    Hobbs, G.4    Miller, M.R.5    Motaleb, M.A.6
  • 64
    • 79959326635 scopus 로고    scopus 로고
    • A novel gene inactivation system reveals an altered periplasmic flagellar orientation in a Borrelia burgdorferi fliL mutant
    • Motaleb MA, Pitzer JE, Sultan SZ, Liu J. 2011. A novel gene inactivation system reveals an altered periplasmic flagellar orientation in a Borrelia burgdorferi fliL mutant. J. Bacteriol. 193:3324-3331.
    • (2011) J. Bacteriol. , vol.193 , pp. 3324-3331
    • Motaleb, M.A.1    Pitzer, J.E.2    Sultan, S.Z.3    Liu, J.4
  • 65
    • 13444293534 scopus 로고    scopus 로고
    • The burgeoning molecular genetics of the Lyme disease spirochaete
    • Rosa PA, Tilly K, Stewart PE. 2005. The burgeoning molecular genetics of the Lyme disease spirochaete. Nat. Rev. Microbiol. 3:129-143.
    • (2005) Nat. Rev. Microbiol. , vol.3 , pp. 129-143
    • Rosa, P.A.1    Tilly, K.2    Stewart, P.E.3
  • 66
    • 0037767321 scopus 로고    scopus 로고
    • Plasmid stability during in vitro propagation of Borrelia burgdorferi assessed at a clonal level
    • Grimm D, Elias AF, Tilly K, Rosa PA. 2003. Plasmid stability during in vitro propagation of Borrelia burgdorferi assessed at a clonal level. Infect. Immun. 71:3138-3145.
    • (2003) Infect. Immun. , vol.71 , pp. 3138-3145
    • Grimm, D.1    Elias, A.F.2    Tilly, K.3    Rosa, P.A.4
  • 68
    • 0142026236 scopus 로고    scopus 로고
    • Experimental infection of Ixodes scapularis larvae (Acari: Ixodidae) by immersion in low passage cultures of Borrelia burgdorferi
    • Policastro PF, Schwan TG. 2003. Experimental infection of Ixodes scapularis larvae (Acari: Ixodidae) by immersion in low passage cultures of Borrelia burgdorferi. J. Med. Entomol. 40:364-370.
    • (2003) J. Med. Entomol. , vol.40 , pp. 364-370
    • Policastro, P.F.1    Schwan, T.G.2
  • 69
    • 42949083309 scopus 로고    scopus 로고
    • A tightly regulated surface protein of Borrelia burgdorferi is not essential to the mouse-tick infectious cycle
    • Stewart PE, Bestor A, Cullen JN, Rosa PA. 2008. A tightly regulated surface protein of Borrelia burgdorferi is not essential to the mouse-tick infectious cycle. Infect. Immun. 76:1970-1978.
    • (2008) Infect. Immun. , vol.76 , pp. 1970-1978
    • Stewart, P.E.1    Bestor, A.2    Cullen, J.N.3    Rosa, P.A.4
  • 71
    • 55849126646 scopus 로고    scopus 로고
    • Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector
    • Battisti JM, Bono JL, Rosa PA, Schrumpf ME, Schwan TG, Policastro PF. 2008. Outer surface protein A protects Lyme disease spirochetes from acquired host immunity in the tick vector. Infect. Immun. 76: 5228-5237.
    • (2008) Infect. Immun. , vol.76 , pp. 5228-5237
    • Battisti, J.M.1    Bono, J.L.2    Rosa, P.A.3    Schrumpf, M.E.4    Schwan, T.G.5    Policastro, P.F.6
  • 72
    • 0025977648 scopus 로고
    • Antibody to a 39-kilodalton Borrelia burgdorferi antigen (P39) as a marker for infection in experimentally and naturally inoculated animals
    • Simpson WJ, Burgdorfer W, Schrumpf ME, Karstens RH, Schwan TG. 1991. Antibody to a 39-kilodalton Borrelia burgdorferi antigen (P39) as a marker for infection in experimentally and naturally inoculated animals. J. Clin. Microbiol. 29:236-243.
    • (1991) J. Clin. Microbiol. , vol.29 , pp. 236-243
    • Simpson, W.J.1    Burgdorfer, W.2    Schrumpf, M.E.3    Karstens, R.H.4    Schwan, T.G.5
  • 73
    • 1542283705 scopus 로고    scopus 로고
    • Essential role for OspA/B in the life cycle of the Lyme disease spirochete
    • Yang XF, Pal U, Alani SM, Fikrig E, Norgard MV. 2004. Essential role for OspA/B in the life cycle of the Lyme disease spirochete. J. Exp. Med. 199:641-648.
    • (2004) J. Exp. Med. , vol.199 , pp. 641-648
    • Yang, X.F.1    Pal, U.2    Alani, S.M.3    Fikrig, E.4    Norgard, M.V.5
  • 74
    • 70349428512 scopus 로고    scopus 로고
    • BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle
    • Zhang X, Yang X, Kumar M, Pal U. 2009. BB0323 function is essential for Borrelia burgdorferi virulence and persistence through tick-rodent transmission cycle. J. Infect. Dis. 200:1318-1330.
    • (2009) J. Infect. Dis. , vol.200 , pp. 1318-1330
    • Zhang, X.1    Yang, X.2    Kumar, M.3    Pal, U.4
  • 75
    • 65249125095 scopus 로고    scopus 로고
    • Borrelia burgdorferi bba74 is expressed exclusively during tick feeding and is regulated by both arthropod- and mammalian host-specific signals
    • Mulay VB, Caimano MJ, Iyer R, Dunham-Ems S, Liveris D, Petzke MM, Schwartz I, Radolf JD. 2009. Borrelia burgdorferi bba74 is expressed exclusively during tick feeding and is regulated by both arthropod- and mammalian host-specific signals. J. Bacteriol. 191:2783-2794.
    • (2009) J. Bacteriol. , vol.191 , pp. 2783-2794
    • Mulay, V.B.1    Caimano, M.J.2    Iyer, R.3    Dunham-Ems, S.4    Liveris, D.5    Petzke, M.M.6    Schwartz, I.7    Radolf, J.D.8
  • 76
    • 79955764702 scopus 로고    scopus 로고
    • Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation
    • doi:10 .1371/journal.pone.0019536
    • Patton TG, Dietrich G, Dolan MC, Piesman J, Carroll JA, Gilmore RD, Jr. 2011. Functional analysis of the Borrelia burgdorferi bba64 gene product in murine infection via tick infestation. PLoS One 6:e19536. doi:10 .1371/journal.pone.0019536.
    • (2011) PLoS One , vol.6
    • Patton, T.G.1    Dietrich, G.2    Dolan, M.C.3    Piesman, J.4    Carroll, J.A.5    Gilmore Jr., R.D.6
  • 77
    • 0025814578 scopus 로고
    • A flagella-less mutant of Borrelia burgdorferi. Structural, molecular, and in vitro functional characterization
    • Sadziene A, Thomas DD, Bundoc VG, Holt SC, Barbour AG. 1991. A flagella-less mutant of Borrelia burgdorferi. Structural, molecular, and in vitro functional characterization. J. Clin. Invest. 88:82-92.
    • (1991) J. Clin. Invest. , vol.88 , pp. 82-92
    • Sadziene, A.1    Thomas, D.D.2    Bundoc, V.G.3    Holt, S.C.4    Barbour, A.G.5
  • 78
    • 0025973276 scopus 로고
    • Analysis of the Borrelia burgdorferi GeHo fla gene and antigenic characterization of its gene product
    • Gassmann GS, Jacobs E, Deutzmann R, Gobel UB. 1991. Analysis of the Borrelia burgdorferi GeHo fla gene and antigenic characterization of its gene product. J. Bacteriol. 173:1452-1459.
    • (1991) J. Bacteriol. , vol.173 , pp. 1452-1459
    • Gassmann, G.S.1    Jacobs, E.2    Deutzmann, R.3    Gobel, U.B.4
  • 80
    • 0141814623 scopus 로고    scopus 로고
    • The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi
    • Yang XF, Alani SM, Norgard MV. 2003. The response regulator Rrp2 is essential for the expression of major membrane lipoproteins in Borrelia burgdorferi. Proc. Natl. Acad. Sci. U. S. A. 100:11001-11006.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 11001-11006
    • Yang, X.F.1    Alani, S.M.2    Norgard, M.V.3
  • 81
    • 79960963391 scopus 로고    scopus 로고
    • Borrelia burgdorferi requires glycerol for maximum fitness during the tick phase of the enzootic cycle
    • doi:10 .1371/journal.ppat.1002102
    • Pappas CJ, Iyer R, Petzke MM, Caimano MJ, Radolf J, Schwartz I. 2011. Borrelia burgdorferi requires glycerol for maximum fitness during the tick phase of the enzootic cycle. PLoS Pathog. 7:e1002102. doi:10 .1371/journal.ppat.1002102.
    • (2011) PLoS Pathog. , vol.7
    • Pappas, C.J.1    Iyer, R.2    Petzke, M.M.3    Caimano, M.J.4    Radolf, J.5    Schwartz, I.6
  • 82
    • 0034610332 scopus 로고    scopus 로고
    • Correlation between plasmid content and infectivity in Borrelia burgdorferi
    • Purser JE, Norris SJ. 2000. Correlation between plasmid content and infectivity in Borrelia burgdorferi. Proc. Natl. Acad. Sci. U. S. A. 97: 13865-13870.
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 13865-13870
    • Purser, J.E.1    Norris, S.J.2
  • 83
    • 0029779949 scopus 로고    scopus 로고
    • Correlation of plasmids with infectivity of Borrelia burgdorferi sensu stricto type strain B31
    • Xu YN, Kodner C, Coleman L, Johnson RC. 1996. Correlation of plasmids with infectivity of Borrelia burgdorferi sensu stricto type strain B31. Infect. Immun. 64:3870-3876.
    • (1996) Infect. Immun. , vol.64 , pp. 3870-3876
    • Xu, Y.N.1    Kodner, C.2    Coleman, L.3    Johnson, R.C.4
  • 84
    • 0035168567 scopus 로고    scopus 로고
    • Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1
    • Labandeira-Rey M, Skare JT. 2001. Decreased infectivity in Borrelia burgdorferi strain B31 is associated with loss of linear plasmid 25 or 28-1. Infect. Immun. 69:446-455.
    • (2001) Infect. Immun. , vol.69 , pp. 446-455
    • Labandeira-Rey, M.1    Skare, J.T.2
  • 86
    • 23644454421 scopus 로고    scopus 로고
    • Role of Borrelia burgdorferi linear plasmid 25 in infection of Ixodes scapularis ticks
    • Strother KO, De Silva A. 2005. Role of Borrelia burgdorferi linear plasmid 25 in infection of Ixodes scapularis ticks. J. Bacteriol. 187:5776-5781.
    • (2005) J. Bacteriol. , vol.187 , pp. 5776-5781
    • Strother, K.O.1    De Silva, A.2
  • 87
    • 25144520842 scopus 로고    scopus 로고
    • The ability of Proteus mirabilis to sense surfaces and regulate virulence gene expression involves FliL, a flagellar basal body protein
    • Belas R, Suvanasuthi R. 2005. The ability of Proteus mirabilis to sense surfaces and regulate virulence gene expression involves FliL, a flagellar basal body protein. J. Bacteriol. 187:6789-6803.
    • (2005) J. Bacteriol. , vol.187 , pp. 6789-6803
    • Belas, R.1    Suvanasuthi, R.2
  • 88
    • 84855295481 scopus 로고    scopus 로고
    • Polar flagellar biosynthesis and a regulator of flagellar number influence spatial parameters of cell division in Campylobacter jejuni
    • doi:10.1371/journal .ppat.1002420
    • Balaban M, Hendrixson DR. 2011. Polar flagellar biosynthesis and a regulator of flagellar number influence spatial parameters of cell division in Campylobacter jejuni. PLoS Pathog. 7:e1002420. doi:10.1371/journal .ppat.1002420.
    • (2011) PLoS Pathog. , vol.7
    • Balaban, M.1    Hendrixson, D.R.2
  • 89
    • 0037022354 scopus 로고    scopus 로고
    • DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete
    • Revel AT, Talaat AM, Norgard MV. 2002. DNA microarray analysis of differential gene expression in Borrelia burgdorferi, the Lyme disease spirochete. Proc. Natl. Acad. Sci. U. S. A. 99:1562-1567.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 1562-1567
    • Revel, A.T.1    Talaat, A.M.2    Norgard, M.V.3
  • 90
    • 79960955642 scopus 로고    scopus 로고
    • The hybrid sensory histidine kinase Hk1 (BB0420) of Borrelia burgdorferi is part of a twocomponent system essential for survival in feeding larval and nymphal Ixodes scapularis ticks
    • Caimano MJ, Kenedy MR, Kairu T, Desrosiers DD, Harman M, Dunham-Ems S, Akins D, Pal U, Radolf JD. 2011. The hybrid sensory histidine kinase Hk1 (BB0420) of Borrelia burgdorferi is part of a twocomponent system essential for survival in feeding larval and nymphal Ixodes scapularis ticks. Infect. Immun. 79:3117-3130.
    • (2011) Infect. Immun. , vol.79 , pp. 3117-3130
    • Caimano, M.J.1    Kenedy, M.R.2    Kairu, T.3    Desrosiers, D.D.4    Harman, M.5    Dunham-Ems, S.6    Akins, D.7    Pal, U.8    Radolf, J.D.9
  • 91
    • 0029642016 scopus 로고
    • Notice to readers recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease
    • CDC
    • CDC. 1995. Notice to readers recommendations for test performance and interpretation from the Second National Conference on Serologic Diagnosis of Lyme Disease. MMWR Morb. Mort. Wkly. Rep. 44:590-591.
    • (1995) MMWR Morb. Mort. Wkly. Rep. , vol.44 , pp. 590-591
  • 92
    • 0028836597 scopus 로고
    • Immunoblot interpretation criteria for serodiagnosis of early Lyme disease
    • Engstrom SM, Shoop E, Johnson RC. 1995. Immunoblot interpretation criteria for serodiagnosis of early Lyme disease. J. Clin. Microbiol. 33: 419-427.
    • (1995) J. Clin. Microbiol. , vol.33 , pp. 419-427
    • Engstrom, S.M.1    Shoop, E.2    Johnson, R.C.3
  • 93
    • 48849115545 scopus 로고    scopus 로고
    • A genome-wide proteome array reveals a limited set of immunogens in natural infections of humans and white-footed mice with Borrelia burgdorferi
    • Barbour AG, Jasinskas A, Kayala MA, Davies DH, Steere AC, Baldi P, Felgner PL. 2008. A genome-wide proteome array reveals a limited set of immunogens in natural infections of humans and white-footed mice with Borrelia burgdorferi. Infect. Immun. 76:3374-3389.
    • (2008) Infect. Immun. , vol.76 , pp. 3374-3389
    • Barbour, A.G.1    Jasinskas, A.2    Kayala, M.A.3    Davies, D.H.4    Steere, A.C.5    Baldi, P.6    Felgner, P.L.7
  • 94
    • 70350461399 scopus 로고    scopus 로고
    • Overexpression of CsrA (BB0184) alters the morphology and antigen profiles of Borrelia burgdorferi
    • Sanjuan E, Esteve-Gassent MD, Maruskova M, Seshu J. 2009. Overexpression of CsrA (BB0184) alters the morphology and antigen profiles of Borrelia burgdorferi. Infect. Immun. 77:5149-5162.
    • (2009) Infect. Immun. , vol.77 , pp. 5149-5162
    • Sanjuan, E.1    Esteve-Gassent, M.D.2    Maruskova, M.3    Seshu, J.4
  • 97
    • 79251480381 scopus 로고    scopus 로고
    • Bb modulates levels of lipoproteins and key regulators of gene expression (RpoS and BosR) critical for pathogenic mechanisms of Borrelia burgdorferi
    • Bb modulates levels of lipoproteins and key regulators of gene expression (RpoS and BosR) critical for pathogenic mechanisms of Borrelia burgdorferi. Infect. Immun. 79:732-744.
    • (2011) Infect. Immun. , vol.79 , pp. 732-744
    • Karna, S.L.R.1    Sanjuan, E.2    Esteve-Gassent, M.D.3    Miller, C.L.4    Maruskova, M.5    Seshu, J.6
  • 98
    • 62449269945 scopus 로고    scopus 로고
    • Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions
    • Rogers EA, Terekhova D, Zhang HM, Hovis KM, Schwartz I, Marconi RT. 2009. Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator of Borrelia burgdorferi core cellular functions. Mol. Microbiol. 71:1551-1573.
    • (2009) Mol. Microbiol. , vol.71 , pp. 1551-1573
    • Rogers, E.A.1    Terekhova, D.2    Zhang, H.M.3    Hovis, K.M.4    Schwartz, I.5    Marconi, R.T.6
  • 100
    • 74549116385 scopus 로고    scopus 로고
    • Investigation of the genes involved in antigenic switching at the vlsE locus in Borrelia burgdorferi: an essential role for the RuvAB branch migrase
    • doi:10.1371/journal.ppat.1000680
    • Dresser AR, Hardy PO, Chaconas G. 2009. Investigation of the genes involved in antigenic switching at the vlsE locus in Borrelia burgdorferi: an essential role for the RuvAB branch migrase. PLoS Pathog. 5:e1000680. doi:10.1371/journal.ppat.1000680.
    • (2009) PLoS Pathog. , vol.5
    • Dresser, A.R.1    Hardy, P.O.2    Chaconas, G.3
  • 101
    • 0031887898 scopus 로고    scopus 로고
    • The Pseudomonas aeruginosa flagellar cap protein, FliD, is responsible for mucin adhesion
    • Arora SK, Ritchings BW, Almira EC, Lory S, Ramphal R. 1998. The Pseudomonas aeruginosa flagellar cap protein, FliD, is responsible for mucin adhesion. Infect. Immun. 66:1000-1007.
    • (1998) Infect. Immun. , vol.66 , pp. 1000-1007
    • Arora, S.K.1    Ritchings, B.W.2    Almira, E.C.3    Lory, S.4    Ramphal, R.5
  • 105
    • 0033945351 scopus 로고    scopus 로고
    • Motility is required to initiate host cell invasion by Yersinia enterocolitica
    • Young GM, Badger JL, Miller VL. 2000. Motility is required to initiate host cell invasion by Yersinia enterocolitica. Infect. Immun. 68:4323-4326.
    • (2000) Infect. Immun. , vol.68 , pp. 4323-4326
    • Young, G.M.1    Badger, J.L.2    Miller, V.L.3
  • 106
    • 0037150709 scopus 로고    scopus 로고
    • Pseudomonas-Candida interactions: an ecological role for virulence factors
    • Hogan DA, Kolter R. 2002. Pseudomonas-Candida interactions: an ecological role for virulence factors. Science 296:2229-2232.
    • (2002) Science , vol.296 , pp. 2229-2232
    • Hogan, D.A.1    Kolter, R.2
  • 107
    • 69049116272 scopus 로고    scopus 로고
    • The RNA binding protein CsrA is a pleiotropic regulator of the locus of enterocyte effacement pathogenicity island of enteropathogenic Escherichia coli
    • Bhatt S, Edwards AN, Nguyen HT, Merlin D, Romeo T, Kalman D. 2009. The RNA binding protein CsrA is a pleiotropic regulator of the locus of enterocyte effacement pathogenicity island of enteropathogenic Escherichia coli. Infect. Immun. 77:3552-3568.
    • (2009) Infect. Immun. , vol.77 , pp. 3552-3568
    • Bhatt, S.1    Edwards, A.N.2    Nguyen, H.T.3    Merlin, D.4    Romeo, T.5    Kalman, D.6
  • 108
    • 0025823864 scopus 로고
    • Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets
    • Eaton KA, Brooks CL, Morgan DR, Krakowka S. 1991. Essential role of urease in pathogenesis of gastritis induced by Helicobacter pylori in gnotobiotic piglets. Infect. Immun. 59:2470-2475.
    • (1991) Infect. Immun. , vol.59 , pp. 2470-2475
    • Eaton, K.A.1    Brooks, C.L.2    Morgan, D.R.3    Krakowka, S.4
  • 109
    • 0026680505 scopus 로고
    • Motility as a factor in the colonisation of gnotobiotic piglets by Helicobacter pylori
    • Eaton KA, Morgan DR, Krakowka S. 1992. Motility as a factor in the colonisation of gnotobiotic piglets by Helicobacter pylori. J. Med. Microbiol. 37:123-127.
    • (1992) J. Med. Microbiol. , vol.37 , pp. 123-127
    • Eaton, K.A.1    Morgan, D.R.2    Krakowka, S.3
  • 110
    • 34047197022 scopus 로고    scopus 로고
    • Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks
    • doi:10.1371/journal.ppat.0030033
    • Neelakanta G, Li X, Pal U, Liu X, Beck DS, Deponte K, Fish D, Kantor FS, Fikrig E. 2007. Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks. PLoS Pathog. 3:e33. doi:10.1371/journal.ppat.0030033.
    • (2007) PLoS Pathog. , vol.3
    • Neelakanta, G.1    Li, X.2    Pal, U.3    Liu, X.4    Beck, D.S.5    Deponte, K.6    Fish, D.7    Kantor, F.S.8    Fikrig, E.9
  • 112
    • 34547965447 scopus 로고    scopus 로고
    • Tick-host-pathogen interactions in Lyme borreliosis
    • Hovius JW, Van Dam AP, Fikrig E. 2007. Tick-host-pathogen interactions in Lyme borreliosis. Trends Parasitol. 23:434-438.
    • (2007) Trends Parasitol. , vol.23 , pp. 434-438
    • Hovius, J.W.1    Van Dam, A.P.2    Fikrig, E.3
  • 114
    • 52049119719 scopus 로고    scopus 로고
    • Molecular characterization and related aspects of the innate immune response in ticks
    • Sonenshine DE, Hynes WL. 2008. Molecular characterization and related aspects of the innate immune response in ticks. Front. Biosci. 13: 7046-7063.
    • (2008) Front. Biosci. , vol.13 , pp. 7046-7063
    • Sonenshine, D.E.1    Hynes, W.L.2
  • 115
    • 0141457796 scopus 로고    scopus 로고
    • Expression of defensin-like peptides in tick hemolymph and midgut in response to challenge with Borrelia burgdorferi, Escherichia coli and Bacillus subtilis
    • Sonenshine DE, Ceraul SM, Hynes WE, Macaluso KR, Azad AF. 2002. Expression of defensin-like peptides in tick hemolymph and midgut in response to challenge with Borrelia burgdorferi, Escherichia coli and Bacillus subtilis. Exp. Appl. Acarol. 28:127-134.
    • (2002) Exp. Appl. Acarol. , vol.28 , pp. 127-134
    • Sonenshine, D.E.1    Ceraul, S.M.2    Hynes, W.E.3    Macaluso, K.R.4    Azad, A.F.5
  • 117
    • 0031587871 scopus 로고    scopus 로고
    • Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice
    • Coleman JL, Gebbia JA, Piesman J, Degen JL, Bugge TH, Benach JL. 1997. Plasminogen is required for efficient dissemination of B. burgdorferi in ticks and for enhancement of spirochetemia in mice. Cell 89:1111-1119.
    • (1997) Cell , vol.89 , pp. 1111-1119
    • Coleman, J.L.1    Gebbia, J.A.2    Piesman, J.3    Degen, J.L.4    Bugge, T.H.5    Benach, J.L.6


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