메뉴 건너뛰기




Volumn 57, Issue 6, 2016, Pages 943-954

Short- and medium-chain fatty acids in energy metabolism: The cellular perspective

Author keywords

Long chain fatty acids; Mitochondria; Short chain fatty acids

Indexed keywords

ACETIC ACID; BUTYRIC ACID; CARBOHYDRATE; CARNITINE; DECANOIC ACID; FATTY ACID BINDING PROTEIN; FORMIC ACID; HEXANOIC ACID; LAURIC ACID; LIPID; MEDIUM CHAIN FATTY ACID; NONANOIC ACID; OCTANOIC ACID; PALMITOYL COENZYME A HYDROLASE; PROPIONIC ACID; REACTIVE OXYGEN METABOLITE; SHORT CHAIN FATTY ACID; TRIACYLGLYCEROL; UNDECANOIC ACID; VALERIC ACID; ACYL COENZYME A; ADENOSINE TRIPHOSPHATE; FATTY ACID;

EID: 84971510696     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.R067629     Document Type: Review
Times cited : (700)

References (161)
  • 2
    • 0023276469 scopus 로고
    • Short chain fatty acids in human large intestine, portal, hepatic and venous blood
    • Cummings, J. H., E. W. J. Pomare, H. W. J. Branch, C. P. E. Naylor, and G. T. MacFarlane. 1987. Short chain fatty acids in human large intestine, portal, hepatic and venous blood. Gut. 28: 1221-1227.
    • (1987) Gut , vol.28 , pp. 1221-1227
    • Cummings, J.H.1    Pomare, E.W.J.2    Branch, H.W.J.3    Naylor, C.P.E.4    MacFarlane, G.T.5
  • 4
    • 0025321505 scopus 로고
    • Energy contributions of volatile fatty acids from the gastrointestinal tract in various species
    • Bergman, E. N. 1990. Energy contributions of volatile fatty acids from the gastrointestinal tract in various species. Physiol. Rev. 70: 567-590.
    • (1990) Physiol. Rev , vol.70 , pp. 567-590
    • Bergman, E.N.1
  • 5
    • 0025232254 scopus 로고
    • Dietary fiber, vegetables, and colon cancer: Critical review and meta-analyses of the epidemiologic evidence
    • Trock, B., E. Lanza, and P. Greenwald. 1990. Dietary fiber, vegetables, and colon cancer: critical review and meta-analyses of the epidemiologic evidence. J. Natl. Cancer Inst. 82: 650-661.
    • (1990) J. Natl. Cancer Inst. , vol.82 , pp. 650-661
    • Trock, B.1    Lanza, E.2    Greenwald, P.3
  • 6
    • 0028859161 scopus 로고
    • Apoptosis in colorectal tumour cells: Induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int
    • Hague, A., D. J. Elder, D. J. Hicks, and C. Paraskeva. 1995. Apoptosis in colorectal tumour cells: induction by the short chain fatty acids butyrate, propionate and acetate and by the bile salt deoxycholate. Int. J. Cancer. 60: 400-406.
    • (1995) J. Cancer. , vol.60 , pp. 400-406
    • Hague, A.1    Elder, D.J.2    Hicks, D.J.3    Paraskeva, C.4
  • 9
    • 84941183248 scopus 로고    scopus 로고
    • The role of short chain fatty acids in appetite regulation and energy homeostasis
    • Byrne, C. S., E. S. Chambers, D. J. Morrison, and G. Frost. 2015. The role of short chain fatty acids in appetite regulation and energy homeostasis. Int. J. Obes. (Lond). 39: 1331-1338.
    • (2015) Int. J. Obes. (Lond) , vol.39 , pp. 1331-1338
    • Byrne, C.S.1    Chambers, E.S.2    Morrison, D.J.3    Frost, G.4
  • 11
    • 84897628732 scopus 로고    scopus 로고
    • Role of the gut microbiota in human nutrition and metabolism
    • Ramakrishna, B. S. 2013. Role of the gut microbiota in human nutrition and metabolism. J. Gastroenterol. Hepatol. 28(Suppl. 4): 9-17.
    • (2013) J. Gastroenterol. Hepatol , vol.28 , pp. 9-17
    • Ramakrishna, B.S.1
  • 12
    • 84866271175 scopus 로고    scopus 로고
    • Mechanism of gene regulation by fatty acids
    • Georgiadi, A., and S. Kersten. 2012. Mechanism of gene regulation by fatty acids. Adv. Nutr. 3: 127-134.
    • (2012) Adv. Nutr , vol.3 , pp. 127-134
    • Georgiadi, A.1    Kersten, S.2
  • 13
    • 84863111550 scopus 로고    scopus 로고
    • PPARs: Fatty acid sensors controlling metabolism
    • Poulsen, L., M. Siersbæk, and S. Mandrup. 2012. PPARs: fatty acid sensors controlling metabolism. Semin. Cell Dev. Biol. 23: 631-639.
    • (2012) Semin. Cell Dev. Biol , vol.23 , pp. 631-639
    • Poulsen, L.1    Siersbæk, M.2    Mandrup, S.3
  • 14
    • 84892144705 scopus 로고    scopus 로고
    • Regulation of the energy metabolism by long-chain fatty acid
    • Nakamura, M. T., B. E. Yudell, and J. J. Loor. 2014. Regulation of the energy metabolism by long-chain fatty acid. Prog. Lipid Res. 53: 124-144.
    • (2014) Prog. Lipid Res , vol.53 , pp. 124-144
    • Nakamura, M.T.1    Yudell, B.E.2    Loor, J.J.3
  • 17
    • 0038555374 scopus 로고    scopus 로고
    • Short-chain fatty acid inhibitors of histone deacetylases: Promising anticancer therapeutics? Curr
    • Chen, J. S., D. V. Faller, and R. A. Spanjaard. 2003. Short-chain fatty acid inhibitors of histone deacetylases: promising anticancer therapeutics? Curr. Cancer Drug Targets. 3: 219-236.
    • (2003) Cancer Drug Targets , vol.3 , pp. 219-236
    • Chen, J.S.1    Faller, D.V.2    Spanjaard, R.A.3
  • 18
    • 79952626445 scopus 로고    scopus 로고
    • Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death
    • Tang, Y., Y. Chen, H. Jiang, and D. Nie. 2011. Short-chain fatty acids induced autophagy serves as an adaptive strategy for retarding mitochondria-mediated apoptotic cell death. Cell Death Differ. 18: 602-618.
    • (2011) Cell Death Differ , vol.18 , pp. 602-618
    • Tang, Y.1    Chen, Y.2    Jiang, H.3    Nie, D.4
  • 19
    • 84890464769 scopus 로고    scopus 로고
    • Induction of apoptosis by the medium-chain length fatty acid lauric acid in colon cancer cells due to induction of oxidative stress
    • Fauser, J. K., G. M. Matthew, A. G. Cummins, and G. S. Howart. 2013. Induction of apoptosis by the medium-chain length fatty acid lauric acid in colon cancer cells due to induction of oxidative stress. Chemotherapy. 59: 214-224.
    • (2013) Chemotherapy , vol.59 , pp. 214-224
    • Fauser, J.K.1    Matthew, G.M.2    Cummins, A.G.3    Howart, G.S.4
  • 21
    • 0020420292 scopus 로고
    • Medium-chain triglycerides: An update. Am
    • Bach, A. C., and V. K. Babayan. 1982. Medium-chain triglycerides: an update. Am. J. Clin. Nutr. 36: 950-962.
    • (1982) J. Clin. Nutr. , vol.36 , pp. 950-962
    • Bach, A.C.1    Babayan, V.K.2
  • 22
    • 0032570977 scopus 로고    scopus 로고
    • Medium chain fatty acid metabolism and energy expenditure: Obesity treatment implications
    • Papamandjaris, A. A., D. E. MacDougall, and P. J. H. Jones. 1998. Medium chain fatty acid metabolism and energy expenditure: obesity treatment implications. Life Sci. 62: 1203-1215.
    • (1998) Life Sci , vol.62 , pp. 1203-1215
    • Papamandjaris, A.A.1    MacDougall, D.E.2    Jones, P.J.H.3
  • 23
    • 0027384310 scopus 로고
    • Effect of fatty acids on the energy coupling processes in mitochondria
    • Wojtczak, L., and P. Schönfeld. 1993. Effect of fatty acids on the energy coupling processes in mitochondria. Biochim. Biophys. Acta. 1183: 41-57.
    • (1993) Biochim. Biophys. Acta , vol.1183 , pp. 41-57
    • Wojtczak, L.1    Schönfeld, P.2
  • 24
    • 0022181816 scopus 로고
    • Membrane lipid composition and cellular function
    • Spector, A. A., and M. A. Yorek. 1985. Membrane lipid composition and cellular function. J. Lipid Res. 26: 1015-1035.
    • (1985) J. Lipid Res. , vol.26 , pp. 1015-1035
    • Spector, A.A.1    Yorek, M.A.2
  • 25
    • 0028881927 scopus 로고
    • Fatty acid composition of adipose tissue in humans. Implications for the dietary fat-serum cholesterol-CHD issue
    • Seidelin, K. N. 1995. Fatty acid composition of adipose tissue in humans. Implications for the dietary fat-serum cholesterol-CHD issue. Prog. Lipid Res. 34: 199-217.
    • (1995) Prog. Lipid Res , vol.34 , pp. 199-217
    • Seidelin, K.N.1
  • 27
    • 33947483856 scopus 로고
    • Dimerization of anions of long-chain fatty acids in aqueous solutions and the hydrophobic properties of the acids
    • Mukerjee, P. 1965. Dimerization of anions of long-chain fatty acids in aqueous solutions and the hydrophobic properties of the acids. J. Phys. Chem. 69: 2821-2827.
    • (1965) J. Phys. Chem. , vol.69 , pp. 2821-2827
    • Mukerjee, P.1
  • 28
    • 0001586373 scopus 로고
    • Hydrophobicity of long chain n-alkyl carboxylic acids as measured by their distribution between heptane and aqueous solutions
    • Smith, R., and C. Tanford. 1973. Hydrophobicity of long chain n-alkyl carboxylic acids as measured by their distribution between heptane and aqueous solutions. Proc. Natl. Acad. Sci. USA. 70: 289-293.
    • (1973) Proc. Natl. Acad. Sci. USA , vol.70 , pp. 289-293
    • Smith, R.1    Tanford, C.2
  • 29
    • 0029885061 scopus 로고    scopus 로고
    • Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes
    • Evtodienko, V. Y., O. N. Kovbasnjuk, Y. N. Antonenko, and L. S. Yaguzhinsky. 1996. Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. Biochim. Biophys. Acta. 1281: 245-251.
    • (1996) Biochim. Biophys. Acta , vol.1281 , pp. 245-251
    • Evtodienko, V.Y.1    Kovbasnjuk, O.N.2    Antonenko, Y.N.3    Yaguzhinsky, L.S.4
  • 30
    • 33747881291 scopus 로고    scopus 로고
    • How fatty acids of different chain length enter and leave cells by free diffusion
    • Kamp, F., and J. A. Hamilton. 2006. How fatty acids of different chain length enter and leave cells by free diffusion. Prostaglandins Leukot. Essent. Fatty Acids. 75: 149-159.
    • (2006) Prostaglandins Leukot. Essent. Fatty Acids , vol.75 , pp. 149-159
    • Kamp, F.1    Hamilton, J.A.2
  • 31
    • 0037050765 scopus 로고    scopus 로고
    • Selfassembled vesicles of monocarboxylic acids and alcohols: Conditions for stability and for encapsulation of biopolymers
    • Apel, C. L., D. W. Deamer, and M. N. Mautner. 2002. Selfassembled vesicles of monocarboxylic acids and alcohols: conditions for stability and for encapsulation of biopolymers. Biochim. Biophys. Acta. 1559: 1-9.
    • (2002) Biochim. Biophys. Acta , vol.1559 , pp. 1-9
    • Apel, C.L.1    Deamer, D.W.2    Mautner, M.N.3
  • 32
    • 0021198314 scopus 로고
    • The ionization behavior of fatty acids and bile acids in micelles and membranes
    • Small, D. M., D. J. Cabral, D. P. Cistola, J. S. Parks, and J. A. Hamilton. 1984. The ionization behavior of fatty acids and bile acids in micelles and membranes. Hepatology. 4(Suppl): 77S-79S.
    • (1984) Hepatology , vol.4 , pp. 77S-79S
    • Small, D.M.1    Cabral, D.J.2    Cistola, D.P.3    Parks, J.S.4    Hamilton, J.A.5
  • 33
    • 0029415097 scopus 로고
    • Apparent pKa of the fatty acids within ordered mixtures of model human stratum corneum lipids
    • Lieckfeldt, R., J. Villalaín, J. C. Gómez-Fernández, and G. Lee. 1995. Apparent pKa of the fatty acids within ordered mixtures of model human stratum corneum lipids. Pharm. Res. 12: 1614-1617.
    • (1995) Pharm. Res. , vol.12 , pp. 1614-1617
    • Lieckfeldt, R.1    Villalaín, J.2    Gómez-Fernández, J.C.3    Lee, G.4
  • 34
    • 0029882856 scopus 로고    scopus 로고
    • Pathways of acetate, propionate, and butyrate formation by the human fecal microbial flora
    • Miller, T. L., and M. J. Wolin. 1996. Pathways of acetate, propionate, and butyrate formation by the human fecal microbial flora. Appl. Environ. Microbiol. 62: 1589-1592.
    • (1996) Appl. Environ. Microbiol , vol.62 , pp. 1589-1592
    • Miller, T.L.1    Wolin, M.J.2
  • 35
    • 0021755004 scopus 로고
    • On the dehydration of (R)-lactate in the fermentation of alanine to propionate by Clostridium propionicum
    • Schweiger, G., and W. Buckel. 1984. On the dehydration of (R)-lactate in the fermentation of alanine to propionate by Clostridium propionicum. FEBS Lett. 171: 79-84.
    • (1984) FEBS Lett. , vol.171 , pp. 79-84
    • Schweiger, G.1    Buckel, W.2
  • 36
    • 0019776566 scopus 로고
    • Role of Megasphaera elsdenii in the fermentation of dl-[2-C]lactate in the rumen of dairy cattle
    • Counotte, G. H., R. A. Prins, R. H. A. M. Janssen, and M. J. A. Debie. 1981. Role of Megasphaera elsdenii in the fermentation of dl-[2-C]lactate in the rumen of dairy cattle. Appl. Environ. Microbiol. 42: 649-655.
    • (1981) Appl. Environ. Microbiol , vol.42 , pp. 649-655
    • Counotte, G.H.1    Prins, R.A.2    Janssen, R.H.A.M.3    Debie, M.J.A.4
  • 38
    • 0018718884 scopus 로고
    • The effect of meat protein and dietary fiber on colonic function and metabolism. II. Bacterial metabolites in feces and urine. Am
    • Cummings, J. H., M. J. Hill, E. S. Bone, W. J. Branch, and D. J. Jenkins. 1979. The effect of meat protein and dietary fiber on colonic function and metabolism. II. Bacterial metabolites in feces and urine. Am. J. Clin. Nutr. 32: 2094-2101.
    • (1979) J. Clin. Nutr. , vol.32 , pp. 2094-2101
    • Cummings, J.H.1    Hill, M.J.2    Bone, E.S.3    Branch, W.J.4    Jenkins, D.J.5
  • 39
    • 51449119654 scopus 로고    scopus 로고
    • Roles of short-chain fatty acid receptors, GPR41 and GPR43, on colonic functions
    • Tazoe, H., Y. Otomo, I. Kaji, R. Tanaka, S. I. Karaki, and A. Kuwahara. 2008. Roles of short-chain fatty acid receptors, GPR41 and GPR43, on colonic functions. J. Physiol. Pharmacol. 59(Suppl. 2): 251-262.
    • (2008) J. Physiol. Pharmacol , vol.59 , pp. 251-262
    • Tazoe, H.1    Otomo, Y.2    Kaji, I.3    Tanaka, R.4    Karaki, S.I.5    Kuwahara, A.6
  • 41
    • 0025313322 scopus 로고
    • A carbohydrate-rich diet not only leads to incorporation of medium-chain fatty acids (6:0-14:0) in milk triglycerides but also in each milk-phospholipid subclass
    • van Beusekom, C., I. A. Martini, H. M. Rutgers, E. R. Boersma, and F. A. Muskiet. 1990. A carbohydrate-rich diet not only leads to incorporation of medium-chain fatty acids (6:0-14:0) in milk triglycerides but also in each milk-phospholipid subclass. Am. J. Clin. Nutr. 52: 326-334.
    • (1990) Am. J. Clin. Nutr. , vol.52 , pp. 326-334
    • Van Beusekom, C.1    Martini, I.A.2    Rutgers, H.M.3    Boersma, E.R.4    Muskiet, A.F.5
  • 42
    • 17244364697 scopus 로고    scopus 로고
    • Fatty acid composition of human milk in Western Iran. Eur
    • Bahrami, G., and Z. Rahimi. 2005. Fatty acid composition of human milk in Western Iran. Eur. J. Clin. Nutr. 59: 494-497.
    • (2005) J. Clin. Nutr. , vol.59 , pp. 494-497
    • Bahrami, G.1    Rahimi, Z.2
  • 43
    • 77957032462 scopus 로고    scopus 로고
    • The peroxisome
    • Principles of Medical Biology3. E. E. Bittar and N. Bittar, editors
    • Masters, C., and D. Crane. 1996. The peroxisome. In Principles of Medical Biology. Vol. 3. E. E. Bittar and N. Bittar, editors. Elsevier, Amsterdam. 39-58.
    • (1996) Elsevier, Amsterdam , pp. 39-58
    • Masters, C.1    Crane, D.2
  • 44
    • 84864125549 scopus 로고    scopus 로고
    • The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism
    • Hunt, M. C., M. I. Siponen, and S. H. E. Alexson. 2012. The emerging role of acyl-CoA thioesterases and acyltransferases in regulating peroxisomal lipid metabolism. Biochim. Biophys. Acta. 1822: 1397-1410.
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1397-1410
    • Hunt, M.C.1    Siponen, M.I.2    Alexson, S.H.E.3
  • 45
    • 0028821792 scopus 로고
    • Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders
    • Onkenhout, W., V. Venizelos, P. F. H. van der Poel, M. P. M. van den Heuvel, and B. J. H. M. Poorthuis. 1995. Identification and quantification of intermediates of unsaturated fatty acid metabolism in plasma of patients with fatty acid oxidation disorders. Clin. Chem. 41: 1467-1474.
    • (1995) Clin. Chem , vol.41 , pp. 1467-1474
    • Onkenhout, W.1    Venizelos, V.2    Van Der Poel, P.F.H.3    Van Den Heuvel, M.P.M.4    Poorthuis, B.J.H.M.5
  • 46
    • 84860241971 scopus 로고    scopus 로고
    • Toxicity of octanoate and decanoate in rat peripheral tissues: Evidence of bioenergetic dysfunction and oxidative damage induction in liver and skeletal muscle
    • Scaini, G., K. R. Simon, A. M. Tonin, E. N. Busanello, A. O. Moura, G. C. Ferreira, M. Wajner, E. L. Streck, and P. F. Schuck. 2012. Toxicity of octanoate and decanoate in rat peripheral tissues: evidence of bioenergetic dysfunction and oxidative damage induction in liver and skeletal muscle. Mol. Cell. Biochem. 361: 329-335.
    • (2012) Mol. Cell. Biochem , vol.361 , pp. 329-335
    • Scaini, G.1    Simon, K.R.2    Tonin, A.M.3    Busanello, E.N.4    Moura, A.O.5    Ferreira, G.C.6    Wajner, M.7    Streck, E.L.8    Schuck, P.F.9
  • 47
    • 0020643332 scopus 로고
    • On the biologic origin of C6-C10-dicarboxylic C6-C10-ω-1-hydroxy monocarboxylic acids in human and rat with acyl-CoA dehydrogenation deficiencies: In vitro studies on the ω- and ω-1-oxidation of medium-chain (c6-c12) fatty acids in human and rat liver
    • Gregersen, N., P. B. Mortensen, and S. Kølvraa. 1983. On the biologic origin of C6-C10-dicarboxylic C6-C10-ω-1-hydroxy monocarboxylic acids in human and rat with acyl-CoA dehydrogenation deficiencies: in vitro studies on the ω- and ω-1-oxidation of medium-chain (C6-C12) fatty acids in human and rat liver. Pediatr. Res. 17: 828-834.
    • (1983) Pediatr. Res. , vol.17 , pp. 828-834
    • Gregersen, N.1    Mortensen, P.B.2    Kølvraa, S.3
  • 48
    • 0021903443 scopus 로고
    • The acyl-CoA dehydrogenation deficiencies. Recent advances in the enzymic characterization and understanding of the metabolic and pathophysiological disturbances in patients with acyl-CoA dehydrogenation deficiencies. Scand
    • Gregersen, N. 1985. The acyl-CoA dehydrogenation deficiencies. Recent advances in the enzymic characterization and understanding of the metabolic and pathophysiological disturbances in patients with acyl-CoA dehydrogenation deficiencies. Scand. J. Clin. Lab. Invest. Suppl. 174: 1-60.
    • (1985) J. Clin. Lab. Invest. Suppl. , vol.174 , pp. 1-60
    • Gregersen, N.1
  • 49
    • 77955441420 scopus 로고    scopus 로고
    • 13 C-Breath tests for clinical investigation of liver mitochondrial function. Eur
    • Grattagliano, I., B. H. Lautenburg, G. Palasciano, and P. Portincasa. 2010.13 C-Breath tests for clinical investigation of liver mitochondrial function. Eur. J. Clin. Invest. 40: 843-850.
    • (2010) J. Clin. Invest , vol.40 , pp. 843-850
    • Grattagliano, I.1    Lautenburg, B.H.2    Palasciano, G.3    Portincasa, P.4
  • 52
    • 0043212093 scopus 로고    scopus 로고
    • Molecular features, regulation, and function of monocarboxylate transporters: Implications for drug delivery
    • Enerson, B. E., and L. R. Drewes. 2003. Molecular features, regulation, and function of monocarboxylate transporters: implications for drug delivery. J. Pharm. Sci. 92: 1531-1544.
    • (2003) J. Pharm. Sci. , vol.92 , pp. 1531-1544
    • Enerson, B.E.1    Drewes, L.R.2
  • 53
    • 84887903682 scopus 로고    scopus 로고
    • Butyrate and colorectal cancer: The role of butyrate transport
    • Gonçalves, P., and F. Martel. 2013. Butyrate and colorectal cancer: the role of butyrate transport. Curr. Drug Metab. 14: 994-1008.
    • (2013) Curr. Drug Metab , vol.14 , pp. 994-1008
    • Gonçalves, P.1    Martel, F.2
  • 54
    • 0028168257 scopus 로고
    • Apical membrane Clbutyrate exchange mechanism of short chain fatty acid stimulation of active chloride absorption in rat distal colon
    • Rajendran, V. M., and H. J. Binder. 1994. Apical membrane Clbutyrate exchange mechanism of short chain fatty acid stimulation of active chloride absorption in rat distal colon. J. Membr. Biol. 141: 51-58.
    • (1994) J. Membr. Biol. , vol.141 , pp. 51-58
    • Rajendran, M.1    Binder, H.J.2
  • 55
    • 0025834234 scopus 로고
    • Mechanism of short-chain fatty acid uptake by apical membrane vesicles of rat distal colon
    • Mascolo, N., V. M. Rajendran, and H. J. Binder. 1991. Mechanism of short-chain fatty acid uptake by apical membrane vesicles of rat distal colon. Gastroenterology. 101: 331-338.
    • (1991) Gastroenterology , vol.101 , pp. 331-338
    • Mascolo, N.1    Rajendran, V.M.2    Binder, H.J.3
  • 56
    • 0031898619 scopus 로고    scopus 로고
    • Nonionic diffusion of short-chain fatty acids across rat colon. Am
    • Charney, A. N., L. Micic, and R. W. Egnor. 1998. Nonionic diffusion of short-chain fatty acids across rat colon. Am. J. Physiol. 274: G518-G524.
    • (1998) J. Physiol. , vol.274 , pp. G518-G524
    • Charney, A.N.1    Micic, L.2    Egnor, R.W.3
  • 57
    • 0025296813 scopus 로고
    • Short-chain fatty acid absorption in the human colon in vitro
    • Sellin, J. H., and R. DeSoignie. 1990. Short-chain fatty acid absorption in the human colon in vitro. Gastroenterology. 99: 676-683.
    • (1990) Gastroenterology , vol.99 , pp. 676-683
    • Sellin, J.H.1    DeSoignie, R.2
  • 58
    • 0022629666 scopus 로고
    • Effects of absorption of large amounts of volatile fatty acids on rat liver metabolism
    • Demigné, C., C. Yacoub, and C. Rémésy. 1986. Effects of absorption of large amounts of volatile fatty acids on rat liver metabolism. J. Nutr. 116: 77-86.
    • (1986) J. Nutr. , vol.116 , pp. 77-86
    • Demigné, C.1    Yacoub, C.2    Rémésy, C.3
  • 59
    • 0015502031 scopus 로고
    • Medium chain fatty acid binding to human plasma albumin
    • Ashbrook, J. D., A. A. Spector, and J. E. Fletcher. 1972. Medium chain fatty acid binding to human plasma albumin. J. Biol. Chem. 247: 7038-7042.
    • (1972) J. Biol. Chem. , vol.247 , pp. 7038-7042
    • Ashbrook, J.D.1    Spector, A.A.2    Fletcher, J.E.3
  • 61
    • 0023849374 scopus 로고
    • Fatty acid metabolism in hepatocytes isolated from rats adapted to high-fat diets containing long- or medium-chain triacylglycerols
    • Pégorier, J. P., P. H. Duée, C. Herbin, P. Y. Laulan, C. Bladée, J. Peret, and J. Girard. 1988. Fatty acid metabolism in hepatocytes isolated from rats adapted to high-fat diets containing long- or medium-chain triacylglycerols. Biochem. J. 249: 801-806.
    • (1988) Biochem J. , vol.249 , pp. 801-806
    • Pégorier, J.P.1    Duée, P.H.2    Herbin, C.3    Laulan, P.Y.4    Bladée, C.5    Peret, J.6    Girard, J.7
  • 62
    • 84926168202 scopus 로고    scopus 로고
    • Effects of different fatty acid chain lengths on fatty acid oxidation-related protein expression levels in rat skeletal muscles
    • Ishizawa, R., K. Masuda, S. Sakata, and A. Nakatani. 2015. Effects of different fatty acid chain lengths on fatty acid oxidation-related protein expression levels in rat skeletal muscles. J. Oleo Sci. 64: 415-421.
    • (2015) J. Oleo Sci. , vol.64 , pp. 415-421
    • Ishizawa, R.1    Masuda, K.2    Sakata, S.3    Nakatani, A.4
  • 64
    • 0035968175 scopus 로고    scopus 로고
    • Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy
    • Hajri, T., A. Ibrahimi, C. T. Coburn, F. F. Knapp, Jr., T. Kurtz, M. Praveneci, and N. A. Abumrad. 2001. Defective fatty acid uptake in the spontaneously hypertensive rat is a primary determinant of altered glucose metabolism, hyperinsulinemia, and myocardial hypertrophy. J. Biol. Chem. 276: 23661-23666.
    • (2001) J. Biol. Chem. , vol.276 , pp. 23661-23666
    • Hajri, T.1    Ibrahimi, A.2    Coburn, C.T.3    Knapp, F.F.4    Kurtz, T.5    Praveneci, M.6    Abumrad, N.A.7
  • 67
    • 84910255215 scopus 로고
    • The concentration of acetate in blood during alcohol metabolism in man
    • Lundquist, F. 1960. The concentration of acetate in blood during alcohol metabolism in man. Acta Physiol. Scand. 175: 97-105.
    • (1960) Acta Physiol. Scand , vol.175 , pp. 97-105
    • Lundquist, F.1
  • 68
    • 0016374763 scopus 로고
    • Formation of free acetate by isolated perfused livers from normal, starved and diabetic rats
    • Seufert, C. D., M. Graf, G. Janson, A. Kuhn, and H. D. Söling. 1974. Formation of free acetate by isolated perfused livers from normal, starved and diabetic rats. Biochem. Biophys. Res. Commun. 57: 901-909.
    • (1974) Biochem. Biophys. Res. Commun. , vol.57 , pp. 901-909
    • Seufert, C.D.1    Graf, M.2    Janson, G.3    Kuhn, A.4    Söling, H.D.5
  • 69
    • 0018341234 scopus 로고
    • Acetyl-coenzyme A deacylase activity in liver is not an artefact. Subcellular distribution and substrate specificity of acetyl-coenzyme A deacylase activities in rat liver
    • Grigat, K. P., K. Koppe, C. D. Seufert, and H. D. Söling. 1979. Acetyl-coenzyme A deacylase activity in liver is not an artefact. Subcellular distribution and substrate specificity of acetyl-coenzyme A deacylase activities in rat liver. Biochem. J. 177: 71-79.
    • (1979) Biochem. J. , vol.177 , pp. 71-79
    • Grigat, K.P.1    Koppe, K.2    Seufert, C.D.3    Söling, H.D.4
  • 70
    • 0035978425 scopus 로고    scopus 로고
    • Production of acetate in the liver and its utilization in peripheral tissues
    • Yamashita, H., T. Kaneyuki, and K. Tagawa. 2001. Production of acetate in the liver and its utilization in peripheral tissues. Biochim. Biophys. Acta. 1532: 79-87.
    • (2001) Biochim. Biophys. Acta , vol.1532 , pp. 79-87
    • Yamashita, H.1    Kaneyuki, T.2    Tagawa, K.3
  • 71
    • 0016440795 scopus 로고
    • The activation of short-chain fatty acids by the soluble fraction of Guinea-pig heart and liver mitochondria
    • Groot, P. H. E. 1975. The activation of short-chain fatty acids by the soluble fraction of guinea-pig heart and liver mitochondria. The search for distinct propionyl-CoA synthase. Biochim. Biophys. Acta. 380: 12-20.
    • (1975) The search for distinct propionyl-CoA synthase. Biochim. Biophys. Acta , vol.380 , pp. 12-20
    • Groot, P.H.E.1
  • 72
    • 0016827869 scopus 로고
    • Organ and intracellular localization of short-chain acyl-CoA synthetases in rat and guineapig
    • Scholte, H. R., and P. H. E. Groot. 1975. Organ and intracellular localization of short-chain acyl-CoA synthetases in rat and guineapig. Biochim. Biophys. Acta. 409: 283-296.
    • (1975) Biochim. Biophys. Acta , vol.409 , pp. 283-296
    • Scholte, H.R.1    Groot, P.H.E.2
  • 73
    • 0035815751 scopus 로고    scopus 로고
    • Acetyl-CoA synthase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate
    • Fujino, T., J. Kondo, M. Ishikawa, K. Morikawa, and T. T. Yamamoto. 2001. Acetyl-CoA synthase 2, a mitochondrial matrix enzyme involved in the oxidation of acetate. J. Biol. Chem. 276: 11420-11426.
    • (2001) J. Biol. Chem. , vol.276 , pp. 11420-11426
    • Fujino, T.1    Kondo, J.2    Ishikawa, M.3    Morikawa, K.4    Yamamoto, T.T.5
  • 74
    • 0015212004 scopus 로고
    • The subcellular distribution of short-chain acyl-CoA synthetase activity in rat tissues
    • Barth, C., M. Sladek, and K. Decker. 1971. The subcellular distribution of short-chain acyl-CoA synthetase activity in rat tissues. Biochim. Biophys. Acta. 248: 24-33.
    • (1971) Biochim. Biophys. Acta , vol.248 , pp. 24-33
    • Barth, C.1    Sladek, M.2    Decker, K.3
  • 75
    • 0018818082 scopus 로고
    • Contribution of cytosolic and mitochondrial acetyl-CoA synthetases to the activation of lipogenic acetate in rat liver
    • Goldberg, R. P., and H. Brunengraber. 1980. Contribution of cytosolic and mitochondrial acetyl-CoA synthetases to the activation of lipogenic acetate in rat liver. Adv. Exp. Med. Biol. 132: 413-418.
    • (1980) Adv. Exp. Med. Biol , vol.132 , pp. 413-418
    • Goldberg, R.P.1    Brunengraber, H.2
  • 79
    • 0014426846 scopus 로고
    • Short-chain fatty acid activation in rat liver. A new assay procedure for the enzymes and studies on their intracellular localization
    • Aas, M., and J. Bremer. 1968. Short-chain fatty acid activation in rat liver. A new assay procedure for the enzymes and studies on their intracellular localization. Biochim. Biophys. Acta. 164: 157-166.
    • (1968) Biochim. Biophys. Acta , vol.164 , pp. 157-166
    • Aas, M.1    Bremer, J.2
  • 80
    • 0032806660 scopus 로고    scopus 로고
    • Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acids
    • Vessey, D. A., M. Kelley, and R. S. Warren. 1999. Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acids. Biochim. Biophys. Acta. 1428: 455-462.
    • (1999) Biochim. Biophys. Acta , vol.1428 , pp. 455-462
    • Vessey, D.A.1    Kelley, M.2    Warren, R.S.3
  • 81
    • 70349612067 scopus 로고    scopus 로고
    • Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines
    • Boomgaarden, I., C. Vock, M. Klapper, and F. Döring. 2009. Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines. Biochem. Genet. 47: 739-748.
    • (2009) Biochem. Genet , vol.47 , pp. 739-748
    • Boomgaarden, I.1    Vock, C.2    Klapper, M.3    Döring, F.4
  • 84
    • 1942481514 scopus 로고    scopus 로고
    • Colonic digestion and absorption of energy from carbohydrates and medium-chain fat in small bowel failure. JPEN
    • Jeppesen, P. B., and P. B. Mortensen. 1999. Colonic digestion and absorption of energy from carbohydrates and medium-chain fat in small bowel failure. JPEN J. Parenter. Enteral Nutr. 23: S101-S105.
    • (1999) J. Parenter. Enteral Nutr. , vol.23 , pp. S101-S105
    • Jeppesen, P.B.1    Mortensen, P.B.2
  • 86
    • 0014055187 scopus 로고
    • Enrichment of depot fat with odd and even numbered medium chain fatty acids
    • Zurier, R. B., R. G. Campbell, S. A. Hashim, and T. B. van Itallie. 1967. Enrichment of depot fat with odd and even numbered medium chain fatty acids. Am. J. Physiol. 212: 291-294.
    • (1967) Am. J. Physiol. , vol.212 , pp. 291-294
    • Zurier, R.B.1    Campbell, R.G.2    Hashim, S.A.3    Van Itallie, T.B.4
  • 87
    • 42549121281 scopus 로고    scopus 로고
    • Medium-chain fatty acids as metabolic therapy in cardiac disease
    • Labarthe, F., R. Gélinas, and C. Des Rosiers. 2008. Medium-chain fatty acids as metabolic therapy in cardiac disease. Cardiovasc. Drugs Ther. 22: 97-106.
    • (2008) Cardiovasc. Drugs Ther , vol.22 , pp. 97-106
    • Labarthe, F.1    Gélinas, R.2    Rosiers, C.D.3
  • 88
    • 84951573076 scopus 로고    scopus 로고
    • Revisiting the metabolism and physiological functions of caprylic acid (C8:0) with special focus on ghrelin octanoylation
    • Lemarié, F., E. Beauchamp, P. Legrand, and V. Rioux. 2016. Revisiting the metabolism and physiological functions of caprylic acid (C8:0) with special focus on ghrelin octanoylation. Biochimie. 120: 40-48.
    • (2016) Biochimie , vol.120 , pp. 40-48
    • Lemarié, F.1    Beauchamp, E.2    Legrand, P.3    Rioux, V.4
  • 89
    • 0016162832 scopus 로고
    • Effects of octanoate and oleate on energy metabolism in the perfused rat liver
    • Debeer, L. J., G. Mannaerts, and P. J. de Scheppe. 1974. Effects of octanoate and oleate on energy metabolism in the perfused rat liver. Eur. J. Biochem. 47: 591-600.
    • (1974) Eur. J. Biochem. , vol.47 , pp. 591-600
    • Debeer, L.J.1    Mannaerts, G.2    De Scheppe, P.J.3
  • 91
    • 0021272481 scopus 로고
    • Influence of fatty acids on energy metabolism1. Stimulation of oxygen consumption, ketogenesis and CO2 production following addition of octanoate and oleate in perfused rat liver
    • Scholz, R., U. Schwabe, and S. Soboll. 1984. Influence of fatty acids on energy metabolism. 1. Stimulation of oxygen consumption, ketogenesis and CO2 production following addition of octanoate and oleate in perfused rat liver. Eur. J. Biochem. 141: 223-230.
    • (1984) Eur. J. Biochem , vol.141 , pp. 223-230
    • Scholz, R.1    Schwabe, U.2    Soboll, S.3
  • 92
    • 0021263925 scopus 로고
    • Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver
    • Soboll, S., S. Gründel, and R. Scholz. 1984. Influence of fatty acids on energy metabolism. 2. Kinetics of changes in metabolic rates and changes in subcellular adenine nucleotide contents and pH gradients following addition of octanoate and oleate in perfused rat liver. Eur. J. Biochem. 141: 231-236.
    • (1984) Eur. J. Biochem , vol.141 , pp. 231-236
    • Soboll, S.1    Gründel, S.2    Scholz, R.3
  • 93
    • 0142149277 scopus 로고    scopus 로고
    • 13 C-NMR spectroscopy in rat skeletal muscle, heart, and liver
    • Walton, M. E., D. Ebert, and R. G. Haller. 2003. Octanoate oxidation measured by 13 C-NMR spectroscopy in rat skeletal muscle, heart, and liver. J. Appl. Physiol. 95: 1908-1916.
    • (2003) J. Appl. Physiol. , vol.95 , pp. 1908-1916
    • Walton, M.E.1    Ebert, D.2    Haller, R.G.3
  • 94
    • 0037707488 scopus 로고    scopus 로고
    • Energy contribution of octanoate to intact rat brain metabolism measured by13 C nuclear magnetic resonance spectroscopy
    • Ebert, D., R. G. Haller, and M. E. Walton. 2003. Energy contribution of octanoate to intact rat brain metabolism measured by13 C nuclear magnetic resonance spectroscopy. J. Neurosci. 23: 5928-5935.
    • (2003) J. Neurosci. , vol.23 , pp. 5928-5935
    • Ebert, D.1    Haller, R.G.2    Walton, M.E.3
  • 95
    • 0023930956 scopus 로고
    • Fatty acid transport through the blood-brain barrier
    • Spector, R. 1988. Fatty acid transport through the blood-brain barrier. J. Neurochem. 50: 639-643.
    • (1988) J. Neurochem. , vol.50 , pp. 639-643
    • Spector, R.1
  • 96
    • 0034938816 scopus 로고    scopus 로고
    • Butyrate impairs energy metabolism in isolated perfused liver of fed rats
    • Beauvieux, M-C., P. Tissier, H. Gin, P. Canioni, and J-L. Gallis. 2001. Butyrate impairs energy metabolism in isolated perfused liver of fed rats. J. Nutr. 131: 1986-1992.
    • (2001) J. Nutr. , vol.131 , pp. 1986-1992
    • Beauvieux, M.-C.1    Tissier, P.2    Gin, H.3    Canioni, P.4    Gallis, J.-L.5
  • 97
    • 35748981809 scopus 로고    scopus 로고
    • Decrease in oxidative phosphorylation yield in presence of butyrate in perfused liver isolated from fed rats
    • Gallis, J-L., P. Tissier, H. Gin, and M-C. Beauvieux. 2007. Decrease in oxidative phosphorylation yield in presence of butyrate in perfused liver isolated from fed rats. BMC Physiol. 7: 8.
    • (2007) BMC Physiol , vol.7 , pp. 8
    • Gallis, J.-L.1    Tissier, P.2    Gin, H.3    Beauvieux, M.-C.4
  • 98
    • 79958769922 scopus 로고    scopus 로고
    • A metabolic link between mitochondrial ATP synthesis and liver glycogen metabolism: NMR study in rats re-fed with butyrate and/or glucose
    • Gallis, J-L., H. Gin, H. Roumes, and M-C. Beauvieux. 2011. A metabolic link between mitochondrial ATP synthesis and liver glycogen metabolism: NMR study in rats re-fed with butyrate and/or glucose. Nutr. Metab. (Lond). 8: 38.
    • (2011) Nutr. Metab.(Lond) , vol.8 , pp. 38
    • Gallis, J.-L.1    Gin, H.2    Roumes, H.3    Beauvieux, M.-C.4
  • 100
    • 0024239555 scopus 로고
    • On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids
    • Schönfeld, P., A. B. Wojtczak, M. J. H. Geelen, W. Kunz, and L. Wojtczak. 1988. On the mechanism of the so-called uncoupling effect of medium- and short-chain fatty acids. Biochim. Biophys. Acta. 936: 280-288.
    • (1988) Biochim. Biophys. Acta , vol.936 , pp. 280-288
    • Schönfeld, P.1    Wojtczak, A.B.2    Geelen, M.J.H.3    Kunz, W.4    Wojtczak, L.5
  • 101
    • 0025308492 scopus 로고
    • The mechanism of stimulation of respiration by fatty acids in isolated hepatocytes
    • Nobes, C. D., W. W. Hay, Jr., and M. D. Brand. 1990. The mechanism of stimulation of respiration by fatty acids in isolated hepatocytes. J. Biol. Chem. 265: 12910-12915.
    • (1990) J. Biol. Chem. , vol.265 , pp. 12910-12915
    • Nobes, C.D.1    Hay, W.W.2    Brand, M.D.3
  • 103
    • 70350539537 scopus 로고    scopus 로고
    • Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: Potent tissue-specific effects of medium-chain fatty acids
    • Turner, N., K. Hariharan, J. TidAng, G. Frangioudakis, S. M. Beale, L. E. Wright, X. Y. Zeng, S. J. Leslie, J. Y. Li, E. W. Kraegen, et al. 2009. Enhancement of muscle mitochondrial oxidative capacity and alterations in insulin action are lipid species dependent: potent tissue-specific effects of medium-chain fatty acids. Diabetes. 58: 2547-2554.
    • (2009) Diabetes , vol.58 , pp. 2547-2554
    • Turner, N.1    Hariharan, K.2    TidAng, J.3    Frangioudakis, G.4    Beale, S.M.5    Wright, L.E.6    Zeng, X.Y.7    Leslie, S.J.8    Li, J.Y.9    Kraegen, E.W.10
  • 105
    • 0036071008 scopus 로고    scopus 로고
    • Treatment of cardiomyopathy and rhabdomyolysis in longchain fat oxidation disorders using an anaplerotic odd-chain triglyceride
    • Roe, C. R., L. Sweetman, D. S. Roe, F. David, and H. Brunengraber. 2002. Treatment of cardiomyopathy and rhabdomyolysis in longchain fat oxidation disorders using an anaplerotic odd-chain triglyceride. J. Clin. Invest. 110: 259-269.
    • (2002) J. Clin. Invest. , vol.110 , pp. 259-269
    • Roe, C.R.1    Sweetman, L.2    Roe, D.S.3    David, F.4    Brunengraber, H.5
  • 106
    • 0026063978 scopus 로고
    • 13c: A comparison of oxidation after oral or parenteral administration in humans
    • Metges, C. C., and G. Wolfram. 1991. Medium- and long-chain triglycerides labelled with 13 C: A comparison of oxidation after oral or parenteral administration in humans. J. Nutr. 121: 31-36.
    • (1991) J. Nutr. , vol.121 , pp. 31-36
    • Metges, C.C.1    Wolfram, G.2
  • 107
    • 0021063825 scopus 로고
    • Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis
    • Nomura, T., A. Iguchi, N. Sakamoto, and R. A. Harris. 1983. Effects of octanoate and acetate upon hepatic glycolysis and lipogenesis. Biochim. Biophys. Acta. 754: 315-320.
    • (1983) Biochim. Biophys. Acta , vol.754 , pp. 315-320
    • Nomura, T.1    Iguchi, A.2    Sakamoto, N.3    Harris, R.A.4
  • 108
    • 0028233560 scopus 로고
    • Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats
    • Morand, C., C. Besson, C. Demigne, and C. Remesy. 1994. Importance of the modulation of glycolysis in the control of lactate metabolism by fatty acids in isolated hepatocytes from fed rats. Arch. Biochem. Biophys. 309: 254-260.
    • (1994) Arch. Biochem. Biophys , vol.309 , pp. 254-260
    • Morand, C.1    Besson, C.2    Demigne, C.3    Remesy, C.4
  • 110
    • 0038481114 scopus 로고    scopus 로고
    • Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules
    • Winiarska, K., J. Dro¿ak, M. Wȩgrzynowicz, A. K. Jagielski, and J. Bryła. 2003. Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules. Metabolism. 52: 739-746.
    • (2003) Metabolism , vol.52 , pp. 739-746
    • Winiarska, K.1    Droiak, J.2    Wȩgrzynowicz, M.3    Jagielski, A.K.4    Bryła, J.5
  • 111
    • 0022352027 scopus 로고
    • Regulation of flux through pyruvate dehydrogenase and pyruvate carboxylase in rat hepatocytes. Eur
    • Agius, L., and G. M. M. Alberti. 1985. Regulation of flux through pyruvate dehydrogenase and pyruvate carboxylase in rat hepatocytes. Eur. J. Biochem. 152: 699-707.
    • (1985) J. Biochem. , vol.152 , pp. 699-707
    • Agius, L.1    Alberti, G.M.M.2
  • 112
    • 0028059889 scopus 로고
    • Medium-chain fatty acids as short-term regulators of hepatic lipogenesis
    • Geelen, M. J. 1994. Medium-chain fatty acids as short-term regulators of hepatic lipogenesis. Biochem. J. 302: 141-146.
    • (1994) Biochem J. , vol.302 , pp. 141-146
    • Geelen, M.J.1
  • 114
    • 0014398336 scopus 로고
    • Interrelationships between fatty acid oxidation and the control of gluconeogenesis in perfused rat liver
    • Williamson, J. R., E. T. Browing, and M. S. Olson. 1968. Interrelationships between fatty acid oxidation and the control of gluconeogenesis in perfused rat liver. Adv. Enzyme Regul. 6: 67-100.
    • (1968) Adv. Enzyme Regul , vol.6 , pp. 67-100
    • Williamson, J.R.1    Browing, E.T.2    Olson, M.S.3
  • 115
    • 70450233538 scopus 로고    scopus 로고
    • Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome
    • Hu, G-X., G-R. Chen, H. Xu, R-S. Ge, and J. Lin. 2010. Activation of the AMP activated protein kinase by short-chain fatty acids is the main mechanism underlying the beneficial effect of a high fiber diet on the metabolic syndrome. Med. Hypotheses. 74: 123-126.
    • (2010) Med. Hypotheses , vol.74 , pp. 123-126
    • Hu, G.-X.1    Chen, G.-R.2    Xu, H.3    Ge, R.-S.4    Lin, J.5
  • 116
    • 84884942214 scopus 로고    scopus 로고
    • 10-Hydroxy-2-decenoic acid, a unique medium-chain fatty acid, activates 5?-AMP-activated protein kinase in L6 myotubes and mice
    • Takikawa, M., A. Kumagai, H. Hirata, M. Soga, Y. Yamashita, M. Ueda, H. Ashida, and T. Tsuda. 2013. 10-Hydroxy-2-decenoic acid, a unique medium-chain fatty acid, activates 5?-AMP-activated protein kinase in L6 myotubes and mice. Mol. Nutr. Food Res. 57: 1794-1802.
    • (2013) Mol. Nutr. Food Res , vol.57 , pp. 1794-1802
    • Takikawa, M.1    Kumagai, A.2    Hirata, H.3    Soga, M.4    Yamashita, Y.5    Ueda, M.6    Ashida, H.7    Tsuda, T.8
  • 117
    • 0041709459 scopus 로고    scopus 로고
    • Octanoate inhibits triglyceride synthesis in 3T3-LI and human adipocytes
    • Guo, W., T. Lei, B. E. Corkey, and J. Han. 2003. Octanoate inhibits triglyceride synthesis in 3T3-LI and human adipocytes. J. Nutr. 133: 2512-2518.
    • (2003) J. Nutr. , vol.133 , pp. 2512-2518
    • Guo, W.1    Lei, T.2    Corkey, B.E.3    Han, J.4
  • 120
    • 84943171033 scopus 로고    scopus 로고
    • Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporal membrane oxygenation in infant swine model. Am
    • Kajimoto, M., D. R. Ledee, A. K. Olson, N. G. Isern, C. Des Rosiers, and M. P. Portman. 2015. Differential effects of octanoate and heptanoate on myocardial metabolism during extracorporal membrane oxygenation in infant swine model. Am. J. Physiol. Heart Circ. Physiol. 309: H1157-H1165.
    • (2015) J. Physiol. Heart Circ. Physiol. , vol.309 , pp. H1157-H1165
    • Kajimoto, M.1    Ledee, D.R.2    Olson, A.K.3    Isern, N.G.4    Rosiers, C.D.5    Portman, M.P.6
  • 121
    • 33745105118 scopus 로고    scopus 로고
    • Anaplerotic molecules: Current and Future
    • Brunengraber, H., and C. R. Roe. 2006. Anaplerotic molecules: current and Future. J. Inherit. Metab. Dis. 29: 327-331.
    • (2006) J. Inherit. Metab. Dis. , vol.29 , pp. 327-331
    • Brunengraber, H.1    Roe, C.R.2
  • 122
    • 84873411637 scopus 로고    scopus 로고
    • Heptanoate as neural fuel: Energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain
    • Marin-Valencia, I., L. B. Good, Q. Ma, C. R. Malloy, and J. M. Pascual. 2013. Heptanoate as neural fuel: energetic and neurotransmitter precursors in normal and glucose transporter I-deficient (G1D) brain. J. Cereb. Blood Flow Metab. 33: 175-182.
    • (2013) J. Cereb. Blood Flow Metab. , vol.33 , pp. 175-182
    • Marin-Valencia, I.1    Good, L.B.2    Ma, Q.3    Malloy, C.R.4    Pascual, J.M.5
  • 124
    • 77957790307 scopus 로고    scopus 로고
    • Anticonvulsant effects of triheptanoin diet in two mouse chronic seizure models
    • Willis, S., J. Stoll, L. Sweetman, and K. Borges. 2010. Anticonvulsant effects of triheptanoin diet in two mouse chronic seizure models. Neurobiol. Dis. 40: 565-572.
    • (2010) Neurobiol. Dis , vol.40 , pp. 565-572
    • Willis, S.1    Stoll, J.2    Sweetman, L.3    Borges, K.4
  • 125
    • 84864090873 scopus 로고    scopus 로고
    • Triheptanoin-A mediumchain triglyceride with odd chain fatty acids: A new anaperotic anticonvulsant treatment
    • Borges, K., and U. Sonnewald. 2012. Triheptanoin-a mediumchain triglyceride with odd chain fatty acids: a new anaperotic anticonvulsant treatment. Epilepsy Res. 100: 239-244.
    • (2012) Epilepsy Res , vol.100 , pp. 239-244
    • Borges, K.1    Sonnewald, U.2
  • 126
    • 84897115053 scopus 로고    scopus 로고
    • Triheptanoin partially restores levels of tricarboxylic cycle intermediates in the mouse pilocarpine model of epilepsy
    • Hadera, M. G., O. B. Smeland, T. S. McDonald, K. Ni Tan, U. Sonnewald, and K. Borges. 2014. Triheptanoin partially restores levels of tricarboxylic cycle intermediates in the mouse pilocarpine model of epilepsy. J. Neurochem. 129: 107-119.
    • (2014) J. Neurochem. , vol.129 , pp. 107-119
    • Hadera, M.G.1    Smeland, O.B.2    McDonald, T.S.3    Tan, K.N.4    Sonnewald, U.5    Borges, K.6
  • 127
    • 84930637918 scopus 로고    scopus 로고
    • Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin
    • Schwarzkopf, T. M., K. Koch, and J. Klein. 2015. Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience. 300: 201-209.
    • (2015) Neuroscience , vol.300 , pp. 201-209
    • Schwarzkopf, T.M.1    Koch, K.2    Klein, J.3
  • 128
    • 78650179808 scopus 로고    scopus 로고
    • Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
    • Al-Lahham, S. H., M. P. Peppelenbosch, H. Roelofsen, R. J. Vonk, and K. Venema. 2010. Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. Biochim. Biophys. Acta. 1801: 1175-1183.
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 1175-1183
    • Al-Lahham, S.H.1    Peppelenbosch, M.P.2    Roelofsen, H.3    Vonk, R.J.4    Venema, K.5
  • 129
    • 0025930608 scopus 로고
    • Fatty acid circuit as a physiological mechanism of uncoupling of oxidative phosphorylation
    • Skulachev, V. P. 1991. Fatty acid circuit as a physiological mechanism of uncoupling of oxidative phosphorylation. FEBS Lett. 294: 158-162.
    • (1991) FEBS Lett. , vol.294 , pp. 158-162
    • Skulachev, V.P.1
  • 130
    • 0033387853 scopus 로고    scopus 로고
    • Anion carriers in fatty acid-mediated physiological uncoupling
    • Skulachev, V. P. 1999. Anion carriers in fatty acid-mediated physiological uncoupling. J. Bioenerg. Biomembr. 31: 431-445.
    • (1999) J. Bioenerg. Biomembr. , vol.31 , pp. 431-445
    • Skulachev, V.P.1
  • 131
    • 0342614207 scopus 로고    scopus 로고
    • The mechanisms of fatty acid-induced proton permeability of the inner mitochondrial membrane
    • Wojtczak, L., and M. R. Wiȩckowski. 1999. The mechanisms of fatty acid-induced proton permeability of the inner mitochondrial membrane. J. Bioenerg. Biomembr. 31: 447-455.
    • (1999) J. Bioenerg. Biomembr. , vol.31 , pp. 447-455
    • Wojtczak, L.1    Wiȩckowski, M.R.2
  • 132
    • 0036044373 scopus 로고    scopus 로고
    • Mitochondrial energy dissipation by fatty acids: Mechanisms and implications for cell death
    • Bernardi, P., D. Penzo, and L. Wojtczak. 2002. Mitochondrial energy dissipation by fatty acids: Mechanisms and implications for cell death. Vitam. Horm. 65: 97-126.
    • (2002) Vitam. Horm , vol.65 , pp. 97-126
    • Bernardi, P.1    Penzo, D.2    Wojtczak, L.3
  • 133
    • 58049209810 scopus 로고    scopus 로고
    • Evidence for involvement of nonesterified fatty acid protonophoric uncoupling during mitochondrial dysfunction caused by hypoxia and reoxygenation
    • Feldkamp, T., J. M. Weinberg, M. Hörbelt, C. von Kropff, O. Witzke, J. Nürnberger, and A. Kribben. 2009. Evidence for involvement of nonesterified fatty acid protonophoric uncoupling during mitochondrial dysfunction caused by hypoxia and reoxygenation. Nephrol. Dial. Transplant. 24: 43-51.
    • (2009) Nephrol. Dial. Transplant , vol.24 , pp. 43-51
    • Feldkamp, T.1    Weinberg, J.M.2    Hörbelt, M.3    Von Kropff, C.4    Witzke, O.5    Nürnberger, J.6    Kribben, A.7
  • 135
    • 0024388778 scopus 로고
    • Long-chain fatty acids act as protonophoric uncouplers of oxidative phosphorylation in rat liver mitochondria
    • Schönfeld, P., L. Schild, and W. Kunz. 1989. Long-chain fatty acids act as protonophoric uncouplers of oxidative phosphorylation in rat liver mitochondria. Biochim. Biophys. Acta. 977: 266-272.
    • (1989) Biochim. Biophys. Acta , vol.977 , pp. 266-272
    • Schönfeld, P.1    Schild, L.2    Kunz, W.3
  • 136
    • 50949102396 scopus 로고    scopus 로고
    • Within brown-fat cells, UCP1-mediated fatty acid-induced uncoupling is independent of fatty acid metabolism
    • Shabalina, I. G., W. C. Backlund, J. Bar-Tana, B. Cannon, and J. Nedergaard. 2008. Within brown-fat cells, UCP1-mediated fatty acid-induced uncoupling is independent of fatty acid metabolism. Biochim. Biophys. Acta. 1777: 642-650.
    • (2008) Biochim. Biophys. Acta , vol.1777 , pp. 642-650
    • Shabalina, I.G.1    Backlund, W.C.2    Bar-Tana, J.3    Cannon, B.4    Nedergaard, J.5
  • 137
    • 0021350933 scopus 로고
    • Monocarboxylic permeation through lipid bilayer membrane
    • Walter, A., and J. Gutknecht. 1984. Monocarboxylic permeation through lipid bilayer membrane. J. Membr. Biol. 77: 255-264.
    • (1984) J. Membr. Biol. , vol.77 , pp. 255-264
    • Walter, A.1    Gutknecht, J.2
  • 138
    • 0019877735 scopus 로고
    • Fatty acyl coenzyme A-sensitive adenine nucleotide transport in a reconstituted liposome system
    • Woldegiorgis, G., E. Shrago, J. Gipp, and M. Yatvin. 1981. Fatty acyl coenzyme A-sensitive adenine nucleotide transport in a reconstituted liposome system. J. Biol. Chem. 256: 12297-12300.
    • (1981) J. Biol. Chem. , vol.256 , pp. 12297-12300
    • Woldegiorgis, G.1    Shrago, E.2    Gipp, J.3    Yatvin, M.4
  • 139
    • 0021933212 scopus 로고
    • Quantitative analysis of intermediary metabolism in hepatocytes incubated in the presence and absence of glucagon with a substrate mixture containing glucose, ribose, fructose, alanine and acetate
    • Rabkin, M., and J. J. Blum. 1985. Quantitative analysis of intermediary metabolism in hepatocytes incubated in the presence and absence of glucagon with a substrate mixture containing glucose, ribose, fructose, alanine and acetate. Biochem. J. 225: 761-786.
    • (1985) Biochem J. , vol.225 , pp. 761-786
    • Rabkin, M.1    Blum, J.J.2
  • 140
    • 0024591141 scopus 로고
    • Evidence that the production of acetate in rat hepatocytes is a predominantly cytoplasmic process
    • Crabtree, B., M. J. Souter, and S. E. Anderson. 1989. Evidence that the production of acetate in rat hepatocytes is a predominantly cytoplasmic process. Biochem. J. 257: 673-678.
    • (1989) Biochem J. , vol.257 , pp. 673-678
    • Crabtree, B.1    Souter, M.J.2    Anderson, S.E.3
  • 141
    • 0025079711 scopus 로고
    • Measurement of the rates of acetyl-CoA hydrolysis and synthesis from acetate in rat hepatocytes and the role of these fluxes in substrate cycling
    • Crabtree, B., M. J. Gordon, and S. L. Christie. 1990. Measurement of the rates of acetyl-CoA hydrolysis and synthesis from acetate in rat hepatocytes and the role of these fluxes in substrate cycling. Biochem. J. 270: 219-225.
    • (1990) Biochem J. , vol.270 , pp. 219-225
    • Crabtree, B.1    Gordon, M.J.2    Christie, S.L.3
  • 142
    • 0017854835 scopus 로고
    • Intramitochondrial and extramitochondrial concentrations of adenine nucleotides and inorganic phosphate in isolated hepatocytes from fasted rats
    • Akerboom, T. P. M., H. Bookelman, P. F. Zuurendonk, R. van den Meer, and J. M. Tager. 1978. Intramitochondrial and extramitochondrial concentrations of adenine nucleotides and inorganic phosphate in isolated hepatocytes from fasted rats. Eur. J. Biochem. 84: 413-420.
    • (1978) Eur. J. Biochem , vol.84 , pp. 413-420
    • Akerboom, T.P.M.1    Bookelman, H.2    Zuurendonk, P.F.3    Van Den Meer, R.4    Tager, J.M.5
  • 143
    • 0021333872 scopus 로고
    • Relationship of the ATP/ADP ratio to the site of octanoate activation
    • Otto, D. A. 1984. Relationship of the ATP/ADP ratio to the site of octanoate activation. J. Biol. Chem. 259: 5490-5494.
    • (1984) J. Biol. Chem , vol.259 , pp. 5490-5494
    • Otto, D.A.1
  • 144
    • 0021809711 scopus 로고
    • Inhibition of citrulline synthesis by octanoate and its modulation by adenine nucleotides
    • Lutz, W. H., T. P. Geisbuhler, J. D. Pollack, H. J. McClung, and A. J. Merola. 1985. Inhibition of citrulline synthesis by octanoate and its modulation by adenine nucleotides. Biochem. Med. 34: 1-10.
    • (1985) Biochem. Med , vol.34 , pp. 1-10
    • Lutz, W.H.1    Geisbuhler, T.P.2    Pollack, J.D.3    McClung, H.J.4    Merola, A.J.5
  • 145
    • 0025942391 scopus 로고
    • Intramitochondrial fatty acid activation enhances control strength of the adenine nucleotide translocase
    • Schönfeld, P., and R. Bohnensack. 1991. Intramitochondrial fatty acid activation enhances control strength of the adenine nucleotide translocase. Biomed. Biochim. Acta. 50: 841-849.
    • (1991) Biomed. Biochim. Acta , vol.50 , pp. 841-849
    • Schönfeld, P.1    Bohnensack, R.2
  • 146
    • 0020035826 scopus 로고
    • Enhanced thermogenesis and diminished deposition of fat in response to overfeeding with diet containing medium chain triglyceride. Am
    • Baba, N., E. F. Bracco, and S. A. Hashim. 1982. Enhanced thermogenesis and diminished deposition of fat in response to overfeeding with diet containing medium chain triglyceride. Am. J. Clin. Nutr. 35: 678-682.
    • (1982) J. Clin. Nutr. , vol.35 , pp. 678-682
    • Baba, N.1    Bracco, E.F.2    Hashim, S.A.3
  • 147
    • 0038546461 scopus 로고    scopus 로고
    • Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men
    • St-Onge, M. P., R. Ross, W. D. Parsons, and P. J. H. Jones. 2003. Medium-chain triglycerides increase energy expenditure and decrease adiposity in overweight men. Obes. Res. 11: 395-402.
    • (2003) Obes. Res , vol.11 , pp. 395-402
    • St-Onge, M.P.1    Ross, R.2    Parsons, W.D.3    Jones, P.J.H.4
  • 148
    • 40549115644 scopus 로고    scopus 로고
    • Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil. Am
    • St-Onge, M. P., and A. Bosarge. 2008. Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil. Am. J. Clin. Nutr. 87: 621-626.
    • (2008) J. Clin. Nutr. , vol.87 , pp. 621-626
    • St-Onge, M.P.1    Bosarge, A.2
  • 150
    • 84855503248 scopus 로고    scopus 로고
    • Long- and medium-chain fatty acids induce insulin resistance to a similar extent in humans despite marked differences in muscle fat accumulation
    • Hoeks, J., M. Mensink, M. K. C. Hesselink, K. Ekroos, and P. Schrauwen. 2012. Long- and medium-chain fatty acids induce insulin resistance to a similar extent in humans despite marked differences in muscle fat accumulation. J. Clin. Endocrinol. Metab. 97: 208-216.
    • (2012) J. Clin. Endocrinol. Metab. , vol.97 , pp. 208-216
    • Hoeks, J.1    Mensink, M.2    Hesselink, M.K.C.3    Ekroos, K.4    Schrauwen, P.5
  • 152
    • 52949084673 scopus 로고    scopus 로고
    • Impact of short- and medium-chain organic acids, acylcarnitines, and acyl-CoAs on mitochondrial energy metabolism
    • Sauer, S. W., J. G. Okub, G. F. Hoffmann, S. Koelker, and M. A. Morath. 2008. Impact of short- and medium-chain organic acids, acylcarnitines, and acyl-CoAs on mitochondrial energy metabolism. Biochim. Biophys. Acta. 1777: 1276-1282.
    • (2008) Biochim. Biophys. Acta , vol.1777 , pp. 1276-1282
    • Sauer, S.W.1    Okub, J.G.2    Hoffmann, G.F.3    Koelker, S.4    Morath, M.A.5
  • 153
    • 0037160091 scopus 로고    scopus 로고
    • Topology of superoxide production from different sites in the mitochondrial electron transport chain
    • St-Pierre, J., J. A. Buckingham, S. J. Roebuck, and M. D. Brand. 2002. Topology of superoxide production from different sites in the mitochondrial electron transport chain. J. Biol. Chem. 277: 44784-44790.
    • (2002) J. Biol. Chem. , vol.277 , pp. 44784-44790
    • St-Pierre, J.1    Buckingham, J.A.2    Roebuck, S.J.3    Brand, M.D.4
  • 154
    • 67650248980 scopus 로고    scopus 로고
    • Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions
    • Hoffman, D. L., and P. S. Brookes. 2009. Oxygen sensitivity of mitochondrial reactive oxygen species generation depends on metabolic conditions. J. Biol. Chem. 284: 16236-16245.
    • (2009) J. Biol. Chem. , vol.284 , pp. 16236-16245
    • Hoffman, D.L.1    Brookes, P.S.2
  • 155
    • 77949322975 scopus 로고    scopus 로고
    • Electron transport chain-dependent and independent mechanisms of mitochondrial H2 O2 emission during long-chain fatty acid oxidation
    • Seifert, E. L., C. Estey, J. Y. Xuan, and M. E. Harper. 2010. Electron transport chain-dependent and independent mechanisms of mitochondrial H2 O2 emission during long-chain fatty acid oxidation. J. Biol. Chem. 285: 5748-5758.
    • (2010) J. Biol. Chem. , vol.285 , pp. 5748-5758
    • Seifert, E.L.1    Estey, C.2    Xuan, J.Y.3    Harper, M.E.4
  • 156
    • 77953809888 scopus 로고    scopus 로고
    • Mitochondrial fatty acid oxidation and oxidative stress: Lack of reverse electron transfer-associated production of reactive oxygen species
    • Schönfeld, P., M. R. Wiȩckowski, M. Lebiedzińska, and L. Wojtczak. 2010. Mitochondrial fatty acid oxidation and oxidative stress: Lack of reverse electron transfer-associated production of reactive oxygen species. Biochim. Biophys. Acta. 1797: 929-938.
    • (2010) Biochim. Biophys. Acta , vol.1797 , pp. 929-938
    • Schönfeld, P.1    Wiȩckowski, M.R.2    Lebiedzińska, M.3    Wojtczak, L.4
  • 157
    • 84878009179 scopus 로고    scopus 로고
    • Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria
    • Perevoshchikova, I. V., C. L. Quinlan, A. L. Orr, A. A. Gerencser, and M. D. Brand. 2013. Sites of superoxide and hydrogen peroxide production during fatty acid oxidation in rat skeletal muscle mitochondria. Free Radic. Biol. Med. 61: 298-309.
    • (2013) Free Radic. Biol. Med , vol.61 , pp. 298-309
    • Perevoshchikova, I.V.1    Quinlan, C.L.2    Orr, A.L.3    Gerencser, A.A.4    Brand, M.D.5
  • 158
    • 84855794688 scopus 로고    scopus 로고
    • Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state
    • Schönfeld, P., and L. Wojtczak. 2012. Brown adipose tissue mitochondria oxidizing fatty acids generate high levels of reactive oxygen species irrespective of the uncoupling protein-1 activity state. Biochim. Biophys. Acta. 1817: 410-418.
    • (2012) Biochim. Biophys. Acta , vol.1817 , pp. 410-418
    • Schönfeld, P.1    Wojtczak, L.2
  • 159
    • 79960884485 scopus 로고    scopus 로고
    • Dietary long-chain, but not medium-chain triglycerides, impair exercise performance and uncouple cardiac mitochondria in rats
    • Murray, A. J., N. S. Knight, S. E. Little, L. E. Cochlin, M. Clements, and K. Clarke. 2011. Dietary long-chain, but not medium-chain triglycerides, impair exercise performance and uncouple cardiac mitochondria in rats. Nutr. Metab. (Lond). 8: 55.
    • (2011) Nutr. Metab.(Lond) , vol.8 , pp. 55
    • Murray, A.J.1    Knight, N.S.2    Little, S.E.3    Cochlin, L.E.4    Clements, M.5    Clarke, K.6
  • 160
    • 46449087496 scopus 로고    scopus 로고
    • Fatty acids as modulators of the cellular production of reactive oxygen species
    • Schönfeld, P., and L. Wojtczak. 2008. Fatty acids as modulators of the cellular production of reactive oxygen species. Free Radic. Biol. Med. 45: 231-241.
    • (2008) Free Radic. Biol. Med , vol.45 , pp. 231-241
    • Schönfeld, P.1    Wojtczak, L.2
  • 161
    • 64049107461 scopus 로고    scopus 로고
    • Medium-chain fatty acids accumulating in MCAD deficiency elicit lipid and protein oxidative damage and decrease non-enzymatic antioxidant defenses in rat brain
    • Schuck, P. F., G. C. Ferreira, A. P. Moura, E. N. B. Busanello, A. M. Tonin, C. S. Dutra-Filho, and M. Wajner. 2009. Medium-chain fatty acids accumulating in MCAD deficiency elicit lipid and protein oxidative damage and decrease non-enzymatic antioxidant defenses in rat brain. Neurochem. Int. 54: 519-525.
    • (2009) Neurochem. Int , vol.54 , pp. 519-525
    • Schuck, P.F.1    Ferreira, G.C.2    Moura, A.P.3    Busanello, E.N.B.4    Tonin, A.M.5    Dutra-Filho, C.S.6    Wajner, M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.