Triheptanoin partially restores levels of tricarboxylic acid cycle intermediates in the mouse pilocarpine model of epilepsy

Journal of Neurochemistry

Volumn 129, Issue 1, 2014, Pages 107-119

  Hadera, Mussie G ^a   Smeland, Olav B ^a   McDonald, Tanya S ^b   Tan, Kah Ni ^b   Sonnewald, Ursula ^a   Borges, Karin ^b  

^a NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

anaplerosis; medium chain triglyceride; NMR spectroscopy; seizures; status epilepticus

Indexed keywords

4 AMINOBUTYRIC ACID; ASPARTIC ACID; CARBON 13; CITRIC ACID; MALIC ACID; MESSENGER RNA; PILOCARPINE; PROPIONYL COENZYME A; PYRUVATE CARBOXYLASE; SUCCINIC ACID; TRICARBOXYLIC ACID; TRIHEPTANOIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; CARBOXYLATION; CITRIC ACID CYCLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; EPILEPTIC STATE; FOREBRAIN; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

MUS;

13C ISOTOPE; ANAPLEROSIS; MEDIUM CHAIN TRIGLYCERIDE; NMR SPECTROSCOPY; SEIZURES; STATUS EPILEPTICUS;

ANIMALS; CEREBRAL CORTEX; CITRIC ACID CYCLE; DISEASE MODELS, ANIMAL; EPILEPSY; HIPPOCAMPUS; MALE; MICE; PILOCARPINE; RANDOM ALLOCATION; TRIGLYCERIDES;

EID: 84897115053     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12610     Document Type: Article

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