The histone deacetylase inhibitor butyrate improves metabolism and reduces muscle atrophy during aging

Aging Cell

Volumn 14, Issue 6, 2015, Pages 957-970

  Walsh, Michael E ^a   Bhattacharya, Arunabh ^a,b   Sataranatarajan, Kavithalakshmi ^c   Qaisar, Rizwan ^c   Sloane, Lauren ^b,d   Rahman, Md M ^a   Kinter, Michael ^c   Van Remmen, Holly ^c  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^d SUNY Delhi   (United States)

Author keywords

Aging; Butyrate; Histone deacetylase; Metabolism; Sarcopenia; Skeletal muscle

Indexed keywords

ATROGIN 1; BUTYRIC ACID; ISOCITRATE DEHYDROGENASE 2; PROTEASOME; SUCCINATE DEHYDROGENASE; ANTIOXIDANT; BUTYRIC ACID DERIVATIVE; GLUCOSE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR;

AEROBIC METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BODY COMPOSITION; BODY WEIGHT; BONE DENSITY; BONE MINERAL; CITRIC ACID CYCLE; CONTROLLED STUDY; ENZYMATIC DEGRADATION; ENZYME PHOSPHORYLATION; FAT MASS; FATTY ACID METABOLISM; FEMALE; GENETIC TRANSCRIPTION; GLUCONEOGENESIS; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; GLYCOLYSIS; HINDLIMB MUSCLE; HISTONE ACETYLATION; INSULIN TOLERANCE TEST; LIPID STORAGE; METABOLISM; MITOCHONDRIAL BIOGENESIS; MOUSE; MUSCLE ATROPHY; MUSCLE MASS; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RESPIRATORY CHAIN; RESPIRATORY QUOTIENT; RESTING METABOLIC RATE; SENESCENCE; AGING; ANIMAL; C57BL MOUSE; DRUG EFFECTS; GLUCOSE TOLERANCE TEST; PHYSIOLOGY; SARCOPENIA; SKELETAL MUSCLE;

AGING; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BODY WEIGHT; BUTYRATES; FEMALE; GLUCOSE; GLUCOSE TOLERANCE TEST; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; MICE; MICE, INBRED C57BL; MUSCLE, SKELETAL; OXIDATIVE STRESS; OXYGEN CONSUMPTION; SARCOPENIA;

EID: 84954384433     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12387     Document Type: Article

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