Hepatitis C Virus NS5A Protein Triggers Oxidative Stress by Inducing NADPH Oxidases 1 and 4 and Cytochrome P450 2E1

Oxidative Medicine and Cellular Longevity

Volumn 2016, Issue , 2016, Pages

  Smirnova, Olga A ^a   Ivanova, Olga N ^a   Bartosch, Birke ^b   Valuev Elliston, Vladimir T ^a   Mukhtarov, Furkat ^a   Kochetkov, Sergey N ^a   Ivanov, Alexander V ^a  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b CENTRE DE RECHERCHE EN CANCÉROLOGIE DE LYON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; ENZYME INHIBITION; VIRUSES;

CALCIUM HOMEOSTASIS; CHRONIC HEPATITIS; CYTOCHROME P450; HEPATITIS C VIRUS; INTRACELLULAR CALCIUM; MULTI-STEP MECHANISM; REACTIVE OXYGEN SPECIES; TRANSFORMING GROWTH FACTORS;

OXIDATIVE STRESS;

CALCIUM; CELL PROTEIN; CYTOCHROME P450 2E1; ERO1 PROTEIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; HYDROGEN PEROXIDE; NONSTRUCTURAL PROTEIN 5A; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; CYCLOOXYGENASE 2; ERO1L PROTEIN, HUMAN; ERO1LB PROTEIN, HUMAN; ION; MEMBRANE PROTEIN; NOX1 PROTEIN, HUMAN; NOX4 PROTEIN, HUMAN; NS-5 PROTEIN, HEPATITIS C VIRUS; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; VIRAL PROTEIN;

ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CHRONIC HEPATITIS C; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME INDUCTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PROTEIN DOMAIN; PROTEIN EXPRESSION; VIRUS REPLICATION; BIOSYNTHESIS; CALCIUM SIGNALING; CHEMISTRY; HEPACIVIRUS; METABOLISM; TUMOR CELL LINE;

CALCIUM; CALCIUM SIGNALING; CELL LINE, TUMOR; CYCLOOXYGENASE 2; CYTOCHROME P-450 CYP2E1; ENDOPLASMIC RETICULUM; ENZYME INDUCTION; HEPACIVIRUS; HUMANS; IONS; MEMBRANE GLYCOPROTEINS; NADPH OXIDASE; OXIDATIVE STRESS; OXIDOREDUCTASES; OXIDOREDUCTASES ACTING ON SULFUR GROUP DONORS; PROTEIN DOMAINS; REACTIVE OXYGEN SPECIES; TRANSFORMING GROWTH FACTOR BETA1; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84971483469     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2016/8341937     Document Type: Article

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