NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death during Liver Fibrosis Development

PLoS ONE

Volumn 7, Issue 9, 2012, Pages

  Sancho, Patricia ^a   Mainez, Jèssica ^a   Crosas Molist, Eva ^a   Roncero, César ^b   Fernández Rodriguez, Conrado M ^c   Pinedo, Fernando ^c   Huber, Heidemarie ^d   Eferl, Robert ^d   Mikulits, Wolfgang ^d   Fabregat, Isabel ^a,e  

^a BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c HOSPITAL UNIVERSITARIO FUNDACIÓN ALCORCÓN   (Spain)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TRANSFORMING GROWTH FACTOR BETA;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL DIFFERENTIATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ENZYME ACTIVITY; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION; HEPATITIS C; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER BIOPSY; LIVER CELL; LIVER FIBROSIS; MALE; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; STELLATE CELL; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BIOPSY; CARBON TETRACHLORIDE; CELL TRANSDIFFERENTIATION; CYCLIN-DEPENDENT KINASE INHIBITOR P16; GENE EXPRESSION; HEPACIVIRUS; HEPATIC STELLATE CELLS; HEPATITIS C, CHRONIC; HEPATOCYTES; HUMANS; LIVER; LIVER CIRRHOSIS; MICE; MICE, KNOCKOUT; MYOFIBROBLASTS; NADPH OXIDASE; P-GLYCOPROTEINS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMALIA; HEPATITIS C VIRUS; MUS;

EID: 84866851052     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0045285     Document Type: Article

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