Crystal structure of the FERM-SH2 module of human Jak2

PLoS ONE

Volumn 11, Issue 5, 2016, Pages

  McNally, Randall ^a,b   Toms, Angela V ^a,b,c   Eck, Michael J ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Forma Therapeutics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; JANUS KINASE 2; JANUS KINASE 3; PROTEIN FERM; PROTEIN KINASE TYK2; PROTEIN SH2; UNCLASSIFIED DRUG; JAK2 PROTEIN, HUMAN; PROTEIN BINDING;

ANIMAL CELL; ARTICLE; CRYSTAL STRUCTURE; DNA FLANKING REGION; HUMAN; HYDROPHOBICITY; MUTATIONAL ANALYSIS; NONHUMAN; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; RECEPTOR BINDING; SEVERE COMBINED IMMUNODEFICIENCY; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR MODEL; MUTATION; PHOSPHORYLATION; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; JANUS KINASE 2; MODELS, MOLECULAR; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS;

EID: 84971463428     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0156218     Document Type: Article

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