Molecular modeling of the Jak3 kinase domains and structural basis for severe combined immunodeficiency

Clinical Immunology

Volumn 96, Issue 2, 2000, Pages 108-118

  Vihinen, Mauno ^a,b   Villa, Anna ^c   Mella, Patrizia ^d   Schumacher, R Fabian ^d   Savoldi, Gianfranco ^d   O'Shea, John J ^e   Candotti, Fabio ^d   Notarangelo, Luigi D ^d  

^a UNIVERSITY OF TAMPERE   (Finland)

^b TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^c Ist Tecnologie Biomediche A   (Italy)

^d UNIVERSITY OF BRESCIA   (Italy)

^e NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

B cells; Disease causing mutations; Immunodeficiency; JAK3base; Structural basis of disease; Structure function relationships; T cells

Indexed keywords

JANUS KINASE;

ARTICLE; COMBINED IMMUNODEFICIENCY; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; HUMAN; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN;

EID: 0033859365     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.2000.4880     Document Type: Article

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