NADPH oxidase deficiency underlies dysfunction of aged CD8+ Tregs

Journal of Clinical Investigation

Volumn 126, Issue 5, 2016, Pages 1953-1967

  Wen, Zhenke ^a   Shimojima, Yasuhiro ^a,b   Shirai, Tsuyoshi ^a   Li, Yinyin ^a   Ju, Jihang ^a   Yang, Zhen ^a   Tian, Lu ^a   Goronzy, Jörg J ^a   Weyand, Cornelia M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; PREDNISONE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; CCR7 PROTEIN, HUMAN; CHEMOKINE RECEPTOR CCR7; CYBB PROTEIN, HUMAN; MEMBRANE PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL AGING; CELL EXPANSION; CLINICAL ARTICLE; CONTROLLED STUDY; EX VIVO STUDY; EXOSOME; FEMALE; GIANT CELL ARTERITIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PSORIATIC ARTHRITIS; REGULATORY T LYMPHOCYTE; SMALL VESSEL VASCULITIS; T LYMPHOCYTE ACTIVATION; AGING; DEFICIENCY; ENZYMOLOGY; IMMUNOLOGY; METABOLISM; MIDDLE AGED; PATHOLOGY; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AGING; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; EXOSOMES; FEMALE; GIANT CELL ARTERITIS; HUMANS; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; NADPH OXIDASE; RECEPTORS, CCR7;

EID: 84971309786     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI84181     Document Type: Article

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