Insulin elicits a ROS-activated and an IP3-dependent Ca2+ release, which both impinge on GLUT4 translocation

Journal of Cell Science

Volumn 127, Issue 9, 2014, Pages 1911-1923

  Contreras Ferrat, Ariel ^a,b   Llanos, Paola ^a,b   Vásquez, César ^a   Espinosa, Alejandra ^a   Osorio Fuentealba, César ^a   Arias Calderon, Manuel ^a   Lavandero, Sergio ^a   Klip, Amira ^c   Hidalgo, Cecilia ^a   Jaimovich, Enrique ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Inositol 1,4,5 trisphosphate; Metabolic control; Nox2; Ryr1; Skeletal muscle

Indexed keywords

ACETYLCYSTEINE; ALPHA,BETA PHOSPHATIDYLINOSITOL 3 KINASE; CALCIUM; GLUCOSE TRANSPORTER 4; HYDROGEN PEROXIDE; INOSITOL 1,4,5 TRISPHOSPHATE; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE C; PROTEIN KINASE B; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; RYANODINE RECEPTOR; TROLOX C; UNCLASSIFIED DRUG; CYBB PROTEIN, RAT; MEMBRANE PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVATION; GLUCOSE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; ANIMAL; CELL CULTURE; DRUG EFFECTS; METABOLISM; PROTEIN TRANSPORT; RAT; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CALCIUM; CELLS, CULTURED; GLUCOSE TRANSPORTER TYPE 4; HYDROGEN PEROXIDE; INOSITOL 1,4,5-TRISPHOSPHATE; INSULIN; MEMBRANE GLYCOPROTEINS; MUSCLE, SKELETAL; NADPH OXIDASE; PROTEIN TRANSPORT; RATS; REACTIVE OXYGEN SPECIES;

EID: 84899745823     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.138982     Document Type: Article

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