The Size of Activating and Inhibitory Killer Ig-like Receptor Nanoclusters Is Controlled by the Transmembrane Sequence and Affects Signaling

Cell Reports

Volumn 15, Issue 9, 2016, Pages 1957-1972

  Oszmiana, Anna ^a   Williamson, David J ^a   Cordoba, Shaun Paul ^b   Morgan, David J ^a   Kennedy, Philippa R ^a   Stacey, Kevin ^a   Davis, Daniel M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2 RECEPTOR ALPHA; KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DL1; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 2DS1; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE PHOSPHATASE SHP 1; UNCLASSIFIED DRUG; KIR2DL1 PROTEIN, HUMAN; KIR2DS1 PROTEIN, HUMAN; MEMBRANE PROTEIN; NANOPARTICLE; PROTEIN BINDING; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TYROBP PROTEIN, HUMAN; ZAP70 PROTEIN, HUMAN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; CELL CLONE; CELL LINE; CELL MEMBRANE; CHEMISTRY; METABOLISM; NATURAL KILLER CELL; PHOSPHORYLATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SUBSTITUTION; CELL LINE; CELL MEMBRANE; CLONE CELLS; HUMANS; KILLER CELLS, NATURAL; MEMBRANE PROTEINS; NANOPARTICLES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTORS, KIR; RECEPTORS, KIR2DL1; SIGNAL TRANSDUCTION; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 84971254839     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.04.075     Document Type: Article

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